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Search term: YKL203C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TOR2
SGD link S000001686
Alternative ID YKL203C
Description PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis
Synonyms YKL203C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0891 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA-dependent protein kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g50030 GI:15222859
Caenorhabditis elegans (Cel) CE07705 GI:17505320
Caenorhabditis elegans (Cel) CE27869 GI:17506109
Caenorhabditis elegans (Cel) CE28813 GI:17505322
Drosophila melanogaster (Dme) 7290761 GI:7290761
Drosophila melanogaster (Dme) 7290763 GI:7290763
Drosophila melanogaster (Dme) 7297995
(FBgn0021796)
GI:17864562 Q9VK45
Homo sapiens (Hsa) Hs13654237
(PRKDC)
GI:13654237 P78527
Homo sapiens (Hsa) Hs14719394 GI:14719394
Homo sapiens (Hsa) Hs14778271 GI:14778271
Homo sapiens (Hsa) Hs18765739 GI:18765739
Homo sapiens (Hsa) Hs20562746 GI:20562746
Homo sapiens (Hsa) Hs22067161 GI:22067161
Homo sapiens (Hsa) Hs22067169 GI:22067169
Homo sapiens (Hsa) Hs22067172 GI:20561524
Homo sapiens (Hsa) Hs22070077 GI:22070077
Homo sapiens (Hsa) Hs4826730
(MTOR)
GI:4826730 P42345
Saccharomyces cerevisiae (Sce) YJR066w
(S000003827)
GI:6322526 P35169
Saccharomyces cerevisiae (Sce) YKL203c
(S000001686)
GI:6322646
Schizosaccharomyces pombe (Spo) SPBC216.07c GI:19112151 Q9Y7K2
Schizosaccharomyces pombe (Spo) SPBC30D10.10c GI:19113067 O14356
Arabidopsis thaliana (Ath) At1g50030 GI:15222859
Caenorhabditis elegans (Cel) CE07705 GI:17505320
Caenorhabditis elegans (Cel) CE27869 GI:17506109
Caenorhabditis elegans (Cel) CE28813 GI:17505322
Drosophila melanogaster (Dme) 7290761 GI:7290761
Drosophila melanogaster (Dme) 7290763 GI:7290763
Drosophila melanogaster (Dme) 7297995
(FBgn0021796)
GI:17864562 Q9VK45
Homo sapiens (Hsa) Hs13654237
(PRKDC)
GI:13654237 P78527
Homo sapiens (Hsa) Hs14719394 GI:14719394
Homo sapiens (Hsa) Hs14778271 GI:14778271
Homo sapiens (Hsa) Hs18765739 GI:18765739
Homo sapiens (Hsa) Hs20562746 GI:20562746
Homo sapiens (Hsa) Hs22067161 GI:22067161
Homo sapiens (Hsa) Hs22067169 GI:22067169
Homo sapiens (Hsa) Hs22067172 GI:20561524
Homo sapiens (Hsa) Hs22070077 GI:22070077
Homo sapiens (Hsa) Hs4826730
(MTOR)
GI:4826730 P42345
Saccharomyces cerevisiae (Sce) YJR066w
(S000003827)
GI:6322526 P35169
Saccharomyces cerevisiae (Sce) YKL203c
(S000001686)
GI:6322646
Schizosaccharomyces pombe (Spo) SPBC216.07c GI:19112151 Q9Y7K2
Schizosaccharomyces pombe (Spo) SPBC30D10.10c GI:19113067 O14356


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000003827
GO:0005624 membrane fraction C
IDA
SceS000003827
S000001686
GO:0005634 nucleus C
IDA
SceS000003827
GO:0005654 nucleoplasm C
EXP
HsaPRKDC
GO:0005667 transcription factor complex C
IDA
HsaPRKDC
GO:0005737 cytoplasm C
IDA
HsaMTOR
SceS000003827
SpoSPBC216.07c
SPBC30D10.10c
GO:0005739 mitochondrion C
IDA
SceS000001686
GO:0005774 vacuolar membrane C
IDA
SceS000001686
S000003827
GO:0005829 cytosol C
EXP
HsaMTOR
IDA
SpoSPBC216.07c
SPBC30D10.10c
GO:0005886 plasma membrane C
IDA
SceS000003827
S000001686
GO:0005942 phosphoinositide 3-kinase complex C
NAS
HsaMTOR
GO:0005958 DNA-dependent protein kinase-DNA ligase 4
complex
C
IDA
HsaPRKDC
GO:0010008 endosome membrane C
IDA
SceS000003827
GO:0012505 endomembrane system C
IDA
HsaMTOR
GO:0016020 membrane C
IDA
HsaMTOR
GO:0031234 extrinsic to internal side of plasma
membrane
C
IDA
SceS000001686
S000003827
GO:0031931 TORC1 complex C
IDA
HsaMTOR
SpoSPBC216.07c
IMP
HsaMTOR
IPI
SceS000003827
S000001686
GO:0031932 TORC2 complex C
IDA
HsaMTOR
SpoSPBC30D10.10c
IPI
SceS000001686
GO:0034064 Tor2-Mei2-Ste11 complex C
IDA
SpoSPBC216.07c
GO:0070419 nonhomologous end joining complex C
IDA
HsaPRKDC
GO:0004672 protein kinase activity F
IMP
SceS000003827
NAS
DmeFBgn0021796
TAS
HsaPRKDC
GO:0004674 protein serine/threonine kinase
activity
F
EXP
HsaMTOR
IDA
HsaPRKDC
MTOR
SceS000001686
GO:0004677 DNA-dependent protein kinase activity F
IDA
HsaPRKDC
GO:0005515 protein binding F
IPI
AthAt1g50030
HsaMTOR
PRKDC
SceS000003827
S000001686
SpoSPBC216.07c
GO:0008134 transcription factor binding F
IPI
HsaPRKDC
GO:0016301 kinase activity F
IDA
HsaMTOR
TAS
HsaMTOR
GO:0016303 1-phosphatidylinositol-3-kinase
activity
F
ISS
AthAt1g50030
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0035004 phosphoinositide 3-kinase activity F
NAS
SpoSPBC30D10.10c
GO:0043621 protein self-association F
IDA
DmeFBgn0021796
GO:0051219 phosphoprotein binding F
IPI
HsaMTOR
GO:0000080 G1 phase of mitotic cell cycle P
IMP
SceS000003827
TAS
SceS000001686
GO:0001558 regulation of cell growth P
IDA
DmeFBgn0021796
IMP
SceS000003827
TAS
SceS000001686
S000003827
GO:0006464 protein modification process P
TAS
HsaPRKDC
GO:0006468 protein amino acid phosphorylation P
IDA
HsaMTOR
GO:0006793 phosphorus metabolic process P
RCA
SceS000001686
GO:0006796 phosphate metabolic process P
RCA
SceS000001686
GO:0006914 autophagy P
IMP
DmeFBgn0021796
GO:0006970 response to osmotic stress P
IMP
SpoSPBC30D10.10c
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0021796
SceS000003827
RCA
SceS000001686
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC30D10.10c
GO:0007010 cytoskeleton organization P
IMP
SceS000001686
GO:0007047 cellular cell wall organization P
RCA
SceS000001686
GO:0007126 meiosis P
IMP
SceS000003827
GO:0007165 signal transduction P
IGI
SpoSPBC216.07c
NAS
HsaMTOR
TAS
SceS000001686
S000003827
GO:0007266 Rho protein signal transduction P
IMP
SceS000001686
GO:0007569 cell aging P
TAS
SpoSPBC30D10.10c
GO:0007584 response to nutrient P
NAS
HsaMTOR
TAS
DmeFBgn0021796
GO:0008340 determination of adult lifespan P
IMP
DmeFBgn0021796
GO:0008406 gonad development P
IMP
DmeFBgn0021796
GO:0009266 response to temperature stimulus P
IMP
SpoSPBC30D10.10c
GO:0009267 cellular response to starvation P
IMP
SpoSPBC30D10.10c
GO:0009594 detection of nutrient P
TAS
DmeFBgn0021796
GO:0009793 embryo development ending in seed
dormancy
P
IMP
AthAt1g50030
GO:0009966 regulation of signal transduction P
RCA
SceS000001686
GO:0010503 negative regulation of cell cycle arrest in
response to nitrogen starvation
P
IMP
SpoSPBC216.07c
GO:0010507 negative regulation of autophagy P
IMP
SpoSPBC216.07c
GO:0010515 negative regulation of induction of conjugation
with cellular fusion
P
IMP
SpoSPBC216.07c
GO:0010552 positive regulation of gene-specific transcription
from RNA polymerase II promoter
P
IMP
HsaPRKDC
GO:0016049 cell growth P
TAS
HsaMTOR
GO:0016310 phosphorylation P
IDA
HsaMTOR
NAS
DmeFBgn0021796
GO:0018105 peptidyl-serine phosphorylation P
IDA
HsaPRKDC
IMP
HsaMTOR
GO:0030037 actin filament reorganization involved in cell
cycle
P
TAS
SceS000001686
GO:0030163 protein catabolic process P
TAS
HsaMTOR
GO:0030307 positive regulation of cell growth P
NAS
DmeFBgn0021796
TAS
DmeFBgn0021796
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity
P
IMP
SceS000001686
GO:0030996 cell cycle arrest in response to nitrogen
starvation
P
IMP
SpoSPBC216.07c
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC30D10.10c
GO:0031139 positive regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC30D10.10c
GO:0031142 induction of conjugation upon nitrogen
starvation
P
IMP
SpoSPBC30D10.10c
GO:0031505 fungal-type cell wall organization P
IMP
SceS000003827
GO:0031670 cellular response to nutrient P
NAS
SpoSPBC216.07c
GO:0031929 TOR signaling cascade P
IC
SceS000003827
S000001686
IMP
HsaMTOR
SceS000003827
S000001686
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0031930 mitochondria-nucleus signaling
pathway
P
IMP
SceS000003827
GO:0032456 endocytic recycling P
IDA
DmeFBgn0021796
GO:0032869 cellular response to insulin stimulus P
IMP
HsaPRKDC
GO:0032956 regulation of actin cytoskeleton
organization
P
IMP
HsaMTOR
GO:0033554 cellular response to stress P
IGI
SpoSPBC30D10.10c
SPBC216.07c
IMP
SpoSPBC30D10.10c
GO:0035264 multicellular organism growth P
IMP
DmeFBgn0021796
GO:0040007 growth P
NAS
HsaMTOR
TAS
DmeFBgn0021796
GO:0040018 positive regulation of multicellular organism
growth
P
TAS
DmeFBgn0021796
GO:0042254 ribosome biogenesis P
IMP
SceS000003827
S000001686
GO:0042790 transcription of nuclear rRNA large RNA polymerase
I transcript
P
IMP
SceS000003827
GO:0043091 L-arginine import P
IMP
SpoSPBC30D10.10c
GO:0043200 response to amino acid stimulus P
IDA
HsaMTOR
GO:0045793 positive regulation of cell size P
IMP
DmeFBgn0021796
TAS
DmeFBgn0021796
GO:0045807 positive regulation of endocytosis P
IMP
SceS000001686
GO:0046622 positive regulation of organ growth P
TAS
DmeFBgn0021796
GO:0046777 protein amino acid autophosphorylation P
IDA
HsaMTOR
GO:0046854 phosphoinositide phosphorylation P
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0048015 phosphoinositide-mediated signaling P
NAS
SpoSPBC30D10.10c
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0021796
GO:0051726 regulation of cell cycle P
IMP
SceS000003827
TAS
SceS000001686
GO:0060357 regulation of leucine import P
IMP
SpoSPBC30D10.10c
GO:0090070 positive regulation of ribosome
biogenesis
P
IMP
DmeFBgn0021796

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3637

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MTOR GI:4826730 P42345
Canis familiaris (Cfa) MTOR GI:73950926
Mus musculus (Mmu) Mtor
(MGI:1928394)
GI:9910228 Q2KHT0
Rattus norvegicus (Rno) Mtor GI:9845251
Gallus gallus (Gga) FRAP1 GI:118101095
Drosophila melanogaster (Dme) Tor
(FBgn0021796)
GI:17864562 Q9VK45
Anopheles gambiae (Aga) AgaP_AGAP007873 GI:158297382
Schizosaccharomyces pombe (Spo) tor1
(SPBC30D10.10c)
GI:19113067 O14356
Saccharomyces cerevisiae (Sce) TOR2
(S000001686)
GI:42759860
Kluyveromyces lactis (Kla) KLLA0B13948g GI:50304405
Eremothecium gossypii (Ego) AGOS_AFR420W GI:45198938
Arabidopsis thaliana (Ath) TOR GI:22330143
Oryza sativa (Osa) Os05g0235300 GI:115462777


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000808 origin recognition complex C
ISS
AthTOR
GO:0005618 cell wall C
IDA
AthTOR
GO:0005624 membrane fraction C
IDA
SceS000001686
GO:0005625 soluble fraction C
ISO
MmuMGI:1928394
GO:0005634 nucleus C
IDA
MmuMGI:1928394
ISO
MmuMGI:1928394
ISS
AthTOR
GO:0005737 cytoplasm C
IDA
HsaMTOR
SpoSPBC30D10.10c
GO:0005739 mitochondrion C
IDA
SceS000001686
GO:0005774 vacuolar membrane C
IDA
SceS000001686
GO:0005829 cytosol C
EXP
HsaMTOR
IDA
SpoSPBC30D10.10c
ISO
MmuMGI:1928394
GO:0005886 plasma membrane C
IDA
AthTOR
SceS000001686
GO:0005942 phosphoinositide 3-kinase complex C
NAS
HsaMTOR
GO:0009507 chloroplast C
IDA
AthTOR
GO:0010005 cortical microtubule, transverse to long
axis
C
IDA
AthTOR
GO:0012505 endomembrane system C
IDA
HsaMTOR
GO:0016020 membrane C
IDA
HsaMTOR
GO:0030425 dendrite C
ISO
MmuMGI:1928394
GO:0031234 extrinsic to internal side of plasma
membrane
C
IDA
SceS000001686
GO:0031931 TORC1 complex C
IDA
HsaMTOR
IMP
HsaMTOR
IPI
SceS000001686
ISO
MmuMGI:1928394
GO:0031932 TORC2 complex C
IDA
HsaMTOR
SpoSPBC30D10.10c
IPI
SceS000001686
ISO
MmuMGI:1928394
GO:0043025 neuronal cell body C
ISO
MmuMGI:1928394
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthTOR
GO:0000166 nucleotide binding F
ISS
AthTOR
GO:0003677 DNA binding F
ISS
AthTOR
GO:0004672 protein kinase activity F
NAS
DmeFBgn0021796
GO:0004674 protein serine/threonine kinase
activity
F
EXP
HsaMTOR
IDA
HsaMTOR
MmuMGI:1928394
SceS000001686
ISO
MmuMGI:1928394
GO:0005515 protein binding F
IPI
AthTOR
HsaMTOR
MmuMGI:1928394
SceS000001686
GO:0008017 microtubule binding F
IDA
AthTOR
GO:0008144 drug binding F
ISO
MmuMGI:1928394
GO:0010385 double-stranded methylated DNA
binding
F
IDA
AthTOR
GO:0016301 kinase activity F
IDA
HsaMTOR
ISO
MmuMGI:1928394
TAS
HsaMTOR
GO:0016303 1-phosphatidylinositol-3-kinase
activity
F
ISS
AthTOR
TAS
SpoSPBC30D10.10c
GO:0035004 phosphoinositide 3-kinase activity F
NAS
SpoSPBC30D10.10c
GO:0043621 protein self-association F
IDA
DmeFBgn0021796
GO:0051219 phosphoprotein binding F
IPI
HsaMTOR
GO:0000080 G1 phase of mitotic cell cycle P
TAS
SceS000001686
GO:0001558 regulation of cell growth P
IDA
DmeFBgn0021796
TAS
SceS000001686
GO:0001938 positive regulation of endothelial cell
proliferation
P
ISO
MmuMGI:1928394
GO:0005979 regulation of glycogen biosynthetic
process
P
ISO
MmuMGI:1928394
GO:0006109 regulation of carbohydrate metabolic
process
P
ISO
MmuMGI:1928394
GO:0006260 DNA replication P
ISS
AthTOR
GO:0006468 protein amino acid phosphorylation P
IDA
HsaMTOR
ISO
MmuMGI:1928394
GO:0006793 phosphorus metabolic process P
RCA
SceS000001686
GO:0006796 phosphate metabolic process P
RCA
SceS000001686
GO:0006914 autophagy P
IMP
DmeFBgn0021796
GO:0006970 response to osmotic stress P
IMP
SpoSPBC30D10.10c
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0021796
RCA
SceS000001686
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC30D10.10c
GO:0007010 cytoskeleton organization P
IMP
SceS000001686
GO:0007047 cellular cell wall organization P
RCA
SceS000001686
GO:0007165 signal transduction P
NAS
HsaMTOR
TAS
SceS000001686
GO:0007266 Rho protein signal transduction P
IMP
SceS000001686
GO:0007275 multicellular organismal development P
IMP
AthTOR
GO:0007281 germ cell development P
IDA
MmuMGI:1928394
GO:0007569 cell aging P
TAS
SpoSPBC30D10.10c
GO:0007584 response to nutrient P
NAS
HsaMTOR
TAS
DmeFBgn0021796
GO:0008340 determination of adult lifespan P
IMP
DmeFBgn0021796
GO:0008406 gonad development P
IMP
DmeFBgn0021796
GO:0009266 response to temperature stimulus P
IMP
SpoSPBC30D10.10c
GO:0009267 cellular response to starvation P
IMP
SpoSPBC30D10.10c
GO:0009594 detection of nutrient P
TAS
DmeFBgn0021796
GO:0009793 embryo development ending in seed
dormancy
P
IMP
AthTOR
GO:0009826 unidimensional cell growth P
IMP
AthTOR
GO:0009966 regulation of signal transduction P
RCA
SceS000001686
GO:0010031 circumnutation P
IMP
AthTOR
GO:0010592 positive regulation of lamellipodium
assembly
P
IDA
MmuMGI:1928394
GO:0016049 cell growth P
IMP
AthTOR
TAS
HsaMTOR
GO:0016242 negative regulation of macroautophagy P
IMP
MmuMGI:1928394
GO:0016310 phosphorylation P
IDA
HsaMTOR
NAS
DmeFBgn0021796
GO:0018105 peptidyl-serine phosphorylation P
IMP
HsaMTOR
GO:0018107 peptidyl-threonine phosphorylation P
IDA
MmuMGI:1928394
GO:0030030 cell projection organization P
IMP
MmuMGI:1928394
ISO
MmuMGI:1928394
GO:0030037 actin filament reorganization involved in cell
cycle
P
TAS
SceS000001686
GO:0030163 protein catabolic process P
TAS
HsaMTOR
GO:0030307 positive regulation of cell growth P
NAS
DmeFBgn0021796
TAS
DmeFBgn0021796
GO:0030838 positive regulation of actin filament
polymerization
P
IDA
MmuMGI:1928394
IMP
MmuMGI:1928394
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity
P
IMP
SceS000001686
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC30D10.10c
GO:0031139 positive regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC30D10.10c
GO:0031142 induction of conjugation upon nitrogen
starvation
P
IMP
SpoSPBC30D10.10c
GO:0031529 ruffle organization P
IDA
MmuMGI:1928394
GO:0031929 TOR signaling cascade P
IC
SceS000001686
IMP
HsaMTOR
SceS000001686
TAS
SpoSPBC30D10.10c
GO:0031998 regulation of fatty acid beta-oxidation P
ISO
MmuMGI:1928394
GO:0032095 regulation of response to food P
ISO
MmuMGI:1928394
GO:0032314 regulation of Rac GTPase activity P
IMP
MmuMGI:1928394
GO:0032456 endocytic recycling P
IDA
DmeFBgn0021796
GO:0032868 response to insulin stimulus P
IDA
MmuMGI:1928394
GO:0032956 regulation of actin cytoskeleton
organization
P
IMP
HsaMTOR
GO:0033554 cellular response to stress P
IGI
SpoSPBC30D10.10c
IMP
SpoSPBC30D10.10c
GO:0035264 multicellular organism growth P
IMP
DmeFBgn0021796
GO:0040007 growth P
NAS
HsaMTOR
TAS
DmeFBgn0021796
GO:0040018 positive regulation of multicellular organism
growth
P
TAS
DmeFBgn0021796
GO:0042254 ribosome biogenesis P
IMP
SceS000001686
GO:0043091 L-arginine import P
IMP
SpoSPBC30D10.10c
GO:0043200 response to amino acid stimulus P
IDA
HsaMTOR
MmuMGI:1928394
GO:0043610 regulation of carbohydrate utilization P
ISO
MmuMGI:1928394
GO:0045449 regulation of transcription P
IMP
AthTOR
GO:0045727 positive regulation of translation P
ISO
MmuMGI:1928394
GO:0045792 negative regulation of cell size P
IGI
MmuMGI:1928394
ISO
MmuMGI:1928394
GO:0045793 positive regulation of cell size P
IMP
DmeFBgn0021796
TAS
DmeFBgn0021796
GO:0045807 positive regulation of endocytosis P
IMP
SceS000001686
GO:0045859 regulation of protein kinase activity P
IGI
MmuMGI:1928394
GO:0046622 positive regulation of organ growth P
TAS
DmeFBgn0021796
GO:0046686 response to cadmium ion P
IEP
AthTOR
GO:0046777 protein amino acid autophosphorylation P
IDA
HsaMTOR
ISO
MmuMGI:1928394
GO:0046854 phosphoinositide phosphorylation P
TAS
SpoSPBC30D10.10c
GO:0048015 phosphoinositide-mediated signaling P
NAS
SpoSPBC30D10.10c
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0021796
GO:0050731 positive regulation of peptidyl-tyrosine
phosphorylation
P
IMP
MmuMGI:1928394
GO:0051496 positive regulation of stress fiber
assembly
P
IDA
MmuMGI:1928394
GO:0051726 regulation of cell cycle P
TAS
SceS000001686
GO:0051897 positive regulation of protein kinase B signaling
cascade
P
ISO
MmuMGI:1928394
GO:0060357 regulation of leucine import P
IMP
SpoSPBC30D10.10c
GO:0090070 positive regulation of ribosome
biogenesis
P
IMP
DmeFBgn0021796

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1597

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga9806 ENSANGP00000007283
Anopheles gambiae (Aga) aga9807 ENSANGP00000026022
Ashbya gossypii (Ago) ago3612 AFR420W
Arabidopsis thaliana (Ath) ath4280 At1g50030.1
Caenorhabditis elegans (Cel) cel251 B0261.2a
(CE32559;
WBGene00002583)
Caenorhabditis elegans (Cel) cel252 B0261.2b
(CE32560)
Candida glabrata (Cgl) cgl1253 CAGL0F00495g
Candida glabrata (Cgl) cgl3542 CAGL0K00517g
Cryptococcus neoformans (Cne) cne1237 180.m00175
Dictyostelium discoideum (Ddi) ddi12432 DDB0214908
Debaryomyces hansenii (Dha) dha5497 DEHA0F24882g
Drosophila melanogaster (Dme) dme2201 CG5092-PA
(FBgn0021796)
Danio rerio (Dre) dre23020 ENSDARP00000010271
(wu:fc22h08)
Q06RG6
Danio rerio (Dre) dre25644 ENSDARP00000011806
Danio rerio (Dre) dre25645 ENSDARP00000015414
Danio rerio (Dre) dre29140 ENSDARP00000043359
Takifugu rubripes (Fru) fru29001 SINFRUP00000165820
Takifugu rubripes (Fru) fru29002 SINFRUP00000172758
Takifugu rubripes (Fru) fru29000 SINFRUP00000175943
Gallus gallus (Gga) gga12526 ENSGALP00000004892
Gallus gallus (Gga) gga12529 ENSGALP00000005274
(FRAP1)
Homo sapiens (Hsa) hsa267 ENSP00000354558
(MTOR)
P42345
Homo sapiens (Hsa) hsa268 ENSP00000354587
Kluyveromyces lactis (Kla) kla1150 KLLA0B13948g
Mus musculus (Mmu) mmu19434 ENSMUSP00000054164
(MGI:1928394)
Q9JLN9-2
Neurospora crassa (Ncr) ncr5449 NCU05608.2
Oryza sativa (Osa) osa60799 6423.m00115
Rattus norvegicus (Rno) rno24416 ENSRNOP00000014167
(RGD:68371)
P42346
Saccharomyces cerevisiae (Sce) sce3561 YJR066W
(S000003827)
Saccharomyces cerevisiae (Sce) sce3876 YKL203C
(S000001686)
Schizosaccharomyces pombe (Spo) spo2939 SPBC216.07c Q9Y7K2
Schizosaccharomyces pombe (Spo) spo1799 SPBC30D10.10c O14356
Yarrowia lipolytica (Yli) yli5642 YALI0F07084g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000003827
GO:0005624 membrane fraction C
IDA
SceS000003827
S000001686
GO:0005625 soluble fraction C
ISO
MmuMGI:1928394
GO:0005634 nucleus C
IDA
MmuMGI:1928394
SceS000003827
ISO
MmuMGI:1928394
GO:0005737 cytoplasm C
IDA
CelWBGene00002583
SceS000003827
SpoSPBC216.07c
SPBC30D10.10c
GO:0005739 mitochondrion C
IDA
SceS000001686
GO:0005774 vacuolar membrane C
IDA
SceS000001686
S000003827
GO:0005829 cytosol C
IDA
SpoSPBC216.07c
SPBC30D10.10c
ISO
MmuMGI:1928394
GO:0005886 plasma membrane C
IDA
SceS000003827
S000001686
GO:0010008 endosome membrane C
IDA
SceS000003827
GO:0030425 dendrite C
ISO
MmuMGI:1928394
GO:0031234 extrinsic to internal side of plasma
membrane
C
IDA
SceS000001686
S000003827
GO:0031931 TORC1 complex C
IDA
SpoSPBC216.07c
IPI
SceS000003827
S000001686
ISO
MmuMGI:1928394
GO:0031932 TORC2 complex C
IDA
SpoSPBC30D10.10c
IPI
SceS000001686
ISO
MmuMGI:1928394
GO:0034064 Tor2-Mei2-Ste11 complex C
IDA
SpoSPBC216.07c
GO:0043025 neuronal cell body C
ISO
MmuMGI:1928394
GO:0004672 protein kinase activity F
IMP
SceS000003827
NAS
DmeFBgn0021796
GO:0004674 protein serine/threonine kinase
activity
F
IDA
MmuMGI:1928394
SceS000001686
ISO
MmuMGI:1928394
GO:0005515 protein binding F
IPI
AthAt1g50030
MmuMGI:1928394
SceS000003827
S000001686
SpoSPBC216.07c
GO:0008144 drug binding F
ISO
MmuMGI:1928394
GO:0016301 kinase activity F
ISO
MmuMGI:1928394
GO:0016303 1-phosphatidylinositol-3-kinase
activity
F
ISS
AthAt1g50030
CelWBGene00002583
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0035004 phosphoinositide 3-kinase activity F
NAS
SpoSPBC30D10.10c
GO:0043621 protein self-association F
IDA
DmeFBgn0021796
GO:0000003 reproduction P
IMP
CelWBGene00002583
GO:0000080 G1 phase of mitotic cell cycle P
IMP
SceS000003827
TAS
SceS000001686
GO:0000492 box C/D snoRNP assembly P
IMP
CelWBGene00002583
GO:0001558 regulation of cell growth P
IDA
DmeFBgn0021796
IMP
SceS000003827
TAS
SceS000001686
S000003827
GO:0001938 positive regulation of endothelial cell
proliferation
P
ISO
MmuMGI:1928394
GO:0002119 nematode larval development P
IMP
CelWBGene00002583
GO:0005979 regulation of glycogen biosynthetic
process
P
ISO
MmuMGI:1928394
GO:0006109 regulation of carbohydrate metabolic
process
P
ISO
MmuMGI:1928394
GO:0006412 translation P
IMP
CelWBGene00002583
GO:0006417 regulation of translation P
IMP
CelWBGene00002583
GO:0006468 protein amino acid phosphorylation P
ISO
MmuMGI:1928394
GO:0006629 lipid metabolic process P
IMP
CelWBGene00002583
GO:0006793 phosphorus metabolic process P
RCA
SceS000001686
GO:0006796 phosphate metabolic process P
RCA
SceS000001686
GO:0006914 autophagy P
IMP
DmeFBgn0021796
GO:0006970 response to osmotic stress P
IMP
SpoSPBC30D10.10c
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0021796
SceS000003827
RCA
SceS000001686
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC30D10.10c
GO:0007010 cytoskeleton organization P
IMP
SceS000001686
GO:0007047 cellular cell wall organization P
RCA
SceS000001686
GO:0007126 meiosis P
IMP
SceS000003827
GO:0007165 signal transduction P
IGI
SpoSPBC216.07c
TAS
SceS000001686
S000003827
GO:0007266 Rho protein signal transduction P
IMP
SceS000001686
GO:0007281 germ cell development P
IDA
MmuMGI:1928394
GO:0007569 cell aging P
TAS
SpoSPBC30D10.10c
GO:0007584 response to nutrient P
TAS
DmeFBgn0021796
GO:0008340 determination of adult lifespan P
IGI
CelWBGene00002583
IMP
CelWBGene00002583
DmeFBgn0021796
GO:0008406 gonad development P
IMP
CelWBGene00002583
DmeFBgn0021796
GO:0009266 response to temperature stimulus P
IMP
SpoSPBC30D10.10c
GO:0009267 cellular response to starvation P
IMP
SpoSPBC30D10.10c
GO:0009408 response to heat P
IMP
CelWBGene00002583
GO:0009594 detection of nutrient P
TAS
DmeFBgn0021796
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00002583
GO:0009793 embryo development ending in seed
dormancy
P
IMP
AthAt1g50030
GO:0009966 regulation of signal transduction P
RCA
SceS000001686
GO:0010503 negative regulation of cell cycle arrest in
response to nitrogen starvation
P
IMP
SpoSPBC216.07c
GO:0010507 negative regulation of autophagy P
IMP
SpoSPBC216.07c
GO:0010515 negative regulation of induction of conjugation
with cellular fusion
P
IMP
SpoSPBC216.07c
GO:0010592 positive regulation of lamellipodium
assembly
P
IDA
MmuMGI:1928394
GO:0016242 negative regulation of macroautophagy P
IMP
MmuMGI:1928394
GO:0016310 phosphorylation P
NAS
DmeFBgn0021796
GO:0018107 peptidyl-threonine phosphorylation P
IDA
MmuMGI:1928394
GO:0030030 cell projection organization P
IMP
MmuMGI:1928394
ISO
MmuMGI:1928394
GO:0030037 actin filament reorganization involved in cell
cycle
P
TAS
SceS000001686
GO:0030307 positive regulation of cell growth P
NAS
DmeFBgn0021796
TAS
DmeFBgn0021796
GO:0030838 positive regulation of actin filament
polymerization
P
IDA
MmuMGI:1928394
IMP
MmuMGI:1928394
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity
P
IMP
SceS000001686
GO:0030996 cell cycle arrest in response to nitrogen
starvation
P
IMP
SpoSPBC216.07c
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC30D10.10c
GO:0031139 positive regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC30D10.10c
GO:0031142 induction of conjugation upon nitrogen
starvation
P
IMP
SpoSPBC30D10.10c
GO:0031505 fungal-type cell wall organization P
IMP
SceS000003827
GO:0031529 ruffle organization P
IDA
MmuMGI:1928394
GO:0031670 cellular response to nutrient P
NAS
SpoSPBC216.07c
GO:0031929 TOR signaling cascade P
IC
SceS000003827
S000001686
IMP
CelWBGene00002583
SceS000003827
S000001686
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0031930 mitochondria-nucleus signaling
pathway
P
IMP
SceS000003827
GO:0031998 regulation of fatty acid beta-oxidation P
ISO
MmuMGI:1928394
GO:0032095 regulation of response to food P
ISO
MmuMGI:1928394
GO:0032314 regulation of Rac GTPase activity P
IMP
MmuMGI:1928394
GO:0032456 endocytic recycling P
IDA
DmeFBgn0021796
GO:0032868 response to insulin stimulus P
IDA
MmuMGI:1928394
GO:0033554 cellular response to stress P
IGI
SpoSPBC30D10.10c
SPBC216.07c
IMP
SpoSPBC30D10.10c
GO:0035264 multicellular organism growth P
IMP
DmeFBgn0021796
GO:0040007 growth P
IMP
CelWBGene00002583
TAS
DmeFBgn0021796
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002583
GO:0040018 positive regulation of multicellular organism
growth
P
TAS
DmeFBgn0021796
GO:0042254 ribosome biogenesis P
IMP
SceS000003827
S000001686
GO:0042790 transcription of nuclear rRNA large RNA polymerase
I transcript
P
IMP
SceS000003827
GO:0043053 dauer entry P
IMP
CelWBGene00002583
GO:0043091 L-arginine import P
IMP
SpoSPBC30D10.10c
GO:0043200 response to amino acid stimulus P
IDA
MmuMGI:1928394
GO:0043610 regulation of carbohydrate utilization P
ISO
MmuMGI:1928394
GO:0045727 positive regulation of translation P
IMP
CelWBGene00002583
ISO
MmuMGI:1928394
GO:0045792 negative regulation of cell size P
IGI
MmuMGI:1928394
ISO
MmuMGI:1928394
GO:0045793 positive regulation of cell size P
IMP
DmeFBgn0021796
TAS
DmeFBgn0021796
GO:0045807 positive regulation of endocytosis P
IMP
SceS000001686
GO:0045859 regulation of protein kinase activity P
IGI
MmuMGI:1928394
GO:0046622 positive regulation of organ growth P
TAS
DmeFBgn0021796
GO:0046777 protein amino acid autophosphorylation P
ISO
MmuMGI:1928394
GO:0046854 phosphoinositide phosphorylation P
ISS
CelWBGene00002583
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0048015 phosphoinositide-mediated signaling P
NAS
SpoSPBC30D10.10c
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0021796
GO:0050731 positive regulation of peptidyl-tyrosine
phosphorylation
P
IMP
MmuMGI:1928394
GO:0051496 positive regulation of stress fiber
assembly
P
IDA
MmuMGI:1928394
GO:0051726 regulation of cell cycle P
IMP
SceS000003827
TAS
SceS000001686
GO:0051897 positive regulation of protein kinase B signaling
cascade
P
ISO
MmuMGI:1928394
GO:0060357 regulation of leucine import P
IMP
SpoSPBC30D10.10c
GO:0090070 positive regulation of ribosome
biogenesis
P
IMP
DmeFBgn0021796

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC216.07c
(Q9Y7K2)
YKL203C
(S000001686)
SPBC30D10.10c
(O14356)
YKL203C
(S000001686)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000001686
GO:0005737 cytoplasm C
IDA
SpoSPBC216.07c
SPBC30D10.10c
GO:0005739 mitochondrion C
IDA
SceS000001686
GO:0005774 vacuolar membrane C
IDA
SceS000001686
GO:0005829 cytosol C
IDA
SpoSPBC216.07c
SPBC30D10.10c
GO:0005886 plasma membrane C
IDA
SceS000001686
GO:0031234 extrinsic to internal side of plasma
membrane
C
IDA
SceS000001686
GO:0031931 TORC1 complex C
IDA
SpoSPBC216.07c
IPI
SceS000001686
GO:0031932 TORC2 complex C
IDA
SpoSPBC30D10.10c
IPI
SceS000001686
GO:0034064 Tor2-Mei2-Ste11 complex C
IDA
SpoSPBC216.07c
GO:0004674 protein serine/threonine kinase
activity
F
IDA
SceS000001686
GO:0005515 protein binding F
IPI
SceS000001686
SpoSPBC216.07c
GO:0016303 1-phosphatidylinositol-3-kinase
activity
F
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0035004 phosphoinositide 3-kinase activity F
NAS
SpoSPBC30D10.10c
GO:0000080 G1 phase of mitotic cell cycle P
TAS
SceS000001686
GO:0001558 regulation of cell growth P
TAS
SceS000001686
GO:0006793 phosphorus metabolic process P
RCA
SceS000001686
GO:0006796 phosphate metabolic process P
RCA
SceS000001686
GO:0006970 response to osmotic stress P
IMP
SpoSPBC30D10.10c
GO:0006974 response to DNA damage stimulus P
RCA
SceS000001686
GO:0006995 cellular response to nitrogen starvation P
IMP
SpoSPBC30D10.10c
GO:0007010 cytoskeleton organization P
IMP
SceS000001686
GO:0007047 cellular cell wall organization P
RCA
SceS000001686
GO:0007165 signal transduction P
IGI
SpoSPBC216.07c
TAS
SceS000001686
GO:0007266 Rho protein signal transduction P
IMP
SceS000001686
GO:0007569 cell aging P
TAS
SpoSPBC30D10.10c
GO:0009266 response to temperature stimulus P
IMP
SpoSPBC30D10.10c
GO:0009267 cellular response to starvation P
IMP
SpoSPBC30D10.10c
GO:0009966 regulation of signal transduction P
RCA
SceS000001686
GO:0010503 negative regulation of cell cycle arrest in
response to nitrogen starvation
P
IMP
SpoSPBC216.07c
GO:0010507 negative regulation of autophagy P
IMP
SpoSPBC216.07c
GO:0010515 negative regulation of induction of conjugation
with cellular fusion
P
IMP
SpoSPBC216.07c
GO:0030037 actin filament reorganization involved in cell
cycle
P
TAS
SceS000001686
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity
P
IMP
SceS000001686
GO:0030996 cell cycle arrest in response to nitrogen
starvation
P
IMP
SpoSPBC216.07c
GO:0031137 regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC30D10.10c
GO:0031139 positive regulation of conjugation with cellular
fusion
P
IMP
SpoSPBC30D10.10c
GO:0031142 induction of conjugation upon nitrogen
starvation
P
IMP
SpoSPBC30D10.10c
GO:0031670 cellular response to nutrient P
NAS
SpoSPBC216.07c
GO:0031929 TOR signaling cascade P
IC
SceS000001686
IMP
SceS000001686
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0033554 cellular response to stress P
IGI
SpoSPBC30D10.10c
SPBC216.07c
IMP
SpoSPBC30D10.10c
GO:0042254 ribosome biogenesis P
IMP
SceS000001686
GO:0043091 L-arginine import P
IMP
SpoSPBC30D10.10c
GO:0045807 positive regulation of endocytosis P
IMP
SceS000001686
GO:0046854 phosphoinositide phosphorylation P
TAS
SpoSPBC216.07c
SPBC30D10.10c
GO:0048015 phosphoinositide-mediated signaling P
NAS
SpoSPBC30D10.10c
GO:0051726 regulation of cell cycle P
TAS
SceS000001686
GO:0060357 regulation of leucine import P
IMP
SpoSPBC30D10.10c

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s.khadayate@ucl.ac.uk