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Search term: YKL210W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name UBA1
SGD link S000001693
Alternative ID YKL210W
Description Ubiquitin activating enzyme (E1), involved in ubiquitin-mediated protein degradation and essential for viability
Synonyms YKL210W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2012 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ubiquitin activating enzyme UBA1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g30110 GI:18402264
Arabidopsis thaliana (Ath) At5g06460 GI:18415207
Caenorhabditis elegans (Cel) CE05449
(WBGene00006699)		 GI:17539268
Drosophila melanogaster (Dme) 7303864 GI:17137466
Homo sapiens (Hsa) Hs4507763 GI:4507763
Homo sapiens (Hsa) Hs4507767 GI:4507767
Homo sapiens (Hsa) HsM8922684 GI:8922684
Homo sapiens (Hsa) Hs21361718 GI:11990422 Q8N9E4
Saccharomyces cerevisiae (Sce) YKL210w
(S000001693)		 GI:6322639 P22515
Schizosaccharomyces pombe (Spo) SPBC211.09 GI:19113411
Encephalitozoon cuniculi (Ecu) ECU03g0930 GI:19173051 Q8SS94


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001693
TAS
AthAt5g06460
GO:0005737 cytoplasm C
IDA
SceS000001693
GO:0005886 plasma membrane C
IDA
AthAt2g30110
GO:0004839 ubiquitin activating enzyme activity F
IDA
SceS000001693
IMP
AthAt2g30110
At5g06460
ISS
AthAt5g06460
At2g30110
GO:0004842 ubiquitin-protein ligase activity F
IDA
AthAt2g30110
At5g06460
GO:0000003 reproduction P
IMP
CelWBGene00006699
GO:0002119 nematode larval development P
IMP
CelWBGene00006699
GO:0006508 proteolysis P
RCA
SceS000001693
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
TAS
AthAt5g06460
At2g30110
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00006699
GO:0007283 spermatogenesis P
IMP
CelWBGene00006699
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00006699
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006699
GO:0016567 protein ubiquitination P
IDA
AthAt5g06460
At2g30110
SceS000001693
IMP
CelWBGene00006699
GO:0040007 growth P
IMP
CelWBGene00006699
GO:0045138 tail tip morphogenesis P
IMP
CelWBGene00006699
GO:0046686 response to cadmium ion P
IEP
AthAt2g30110
GO:0048477 oogenesis P
IMP
CelWBGene00006699
GO:0050905 neuromuscular process P
IMP
CelWBGene00006699
GO:0051707 response to other organism P
IMP
AthAt2g30110

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
22002

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) UBA1 GI:23510338
Pan troglodytes (Ptr) UBA1 GI:114691364
Canis familiaris (Cfa) UBA1 GI:74007348
Mus musculus (Mmu) Uba1
(MGI:98890)		 GI:6678483 B9EHN0
Rattus norvegicus (Rno) Uba1 GI:62078893
Drosophila melanogaster (Dme) Uba1
(FBgn0023143)		 GI:28573937
Anopheles gambiae (Aga) AgaP_AGAP011872 GI:158300832
Caenorhabditis elegans (Cel) uba-1
(CE05449;
WBGene00006699)		 GI:86565431
Schizosaccharomyces pombe (Spo) ptr3
(SPBC1604.21c)		 GI:63054800 O94609
Saccharomyces cerevisiae (Sce) UBA1
(S000001693)		 GI:6322639 P22515
Kluyveromyces lactis (Kla) KLLA0B14278g GI:50304433
Eremothecium gossypii (Ego) AGOS_AFR433C GI:45198951
Magnaporthe grisea (Mgr) MGG_01409 GI:39951533
Neurospora crassa (Ncr) NCU04370.1 GI:32406220
Arabidopsis thaliana (Ath) ATUBA1 GI:18402264
Arabidopsis thaliana (Ath) ATUBA2 GI:18415207
Oryza sativa (Osa) Os11g0106400 GI:115483755
Plasmodium falciparum (Pfa) PFL1245w GI:124806199


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPFL1245w
GO:0005634 nucleus C
IDA
SceS000001693
SpoSPBC1604.21c
TAS
AthATUBA2
GO:0005737 cytoplasm C
IDA
SceS000001693
SpoSPBC1604.21c
GO:0005829 cytosol C
IDA
SpoSPBC1604.21c
GO:0005886 plasma membrane C
IDA
AthATUBA1
GO:0030425 dendrite C
IMP
DmeFBgn0023143
GO:0004839 ubiquitin activating enzyme activity F
IDA
SceS000001693
IMP
AthATUBA2
ATUBA1
ISS
AthATUBA2
ATUBA1
DmeFBgn0023143
GO:0004842 ubiquitin-protein ligase activity F
IDA
AthATUBA2
ATUBA1
NAS
DmeFBgn0023143
GO:0005515 protein binding F
IPI
HsaUBA1
GO:0000003 reproduction P
IMP
CelWBGene00006699
GO:0002119 nematode larval development P
IMP
CelWBGene00006699
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC1604.21c
GO:0006508 proteolysis P
RCA
SceS000001693
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
TAS
AthATUBA2
ATUBA1
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00006699
GO:0007283 spermatogenesis P
IMP
CelWBGene00006699
GO:0008283 cell proliferation P
IMP
DmeFBgn0023143
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00006699
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00006699
GO:0016319 mushroom body development P
IMP
DmeFBgn0023143
GO:0016322 neuron remodeling P
IMP
DmeFBgn0023143
GO:0016567 protein ubiquitination P
IDA
AthATUBA1
ATUBA2
SceS000001693
IMP
CelWBGene00006699
DmeFBgn0023143
GO:0019915 lipid storage P
IDA
DmeFBgn0023143
GO:0032446 protein modification by small protein
conjugation		 P
ISS
SpoSPBC1604.21c
GO:0040007 growth P
IMP
CelWBGene00006699
GO:0045138 tail tip morphogenesis P
IMP
CelWBGene00006699
GO:0046578 regulation of Ras protein signal
transduction		 P
IMP
DmeFBgn0023143
GO:0046686 response to cadmium ion P
IEP
AthATUBA1
GO:0048477 oogenesis P
IMP
CelWBGene00006699
GO:0050905 neuromuscular process P
IMP
CelWBGene00006699
GO:0051707 response to other organism P
IMP
AthATUBA1

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_441

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9016 ENSANGP00000025488
Anopheles gambiae (Aga) aga9017 ENSANGP00000025877
Ashbya gossypii (Ago) ago3625 AFR433C
Arabidopsis thaliana (Ath) ath9989 At2g30110.1
Arabidopsis thaliana (Ath) ath22843 At5g06460.1
Caenorhabditis elegans (Cel) cel4255 C47E12.5
Candida glabrata (Cgl) cgl3533 CAGL0K00319g
Cryptococcus neoformans (Cne) cne1930 181.m07900
Dictyostelium discoideum (Ddi) ddi2514 DDB0217880
Dictyostelium discoideum (Ddi) ddi11987 DDB0220497
Debaryomyces hansenii (Dha) dha5220 DEHA0F18645g
Drosophila melanogaster (Dme) dme4125 CG1782-PA
(FBgn0023143)
Danio rerio (Dre) dre15363 ENSDARP00000016734
Encephalitozoon cuniculi (Ecu) ecu458 19173051
Takifugu rubripes (Fru) fru24264 SINFRUP00000148258
Takifugu rubripes (Fru) fru15838 SINFRUP00000149320
Takifugu rubripes (Fru) fru15841 SINFRUP00000149324
Takifugu rubripes (Fru) fru15842 SINFRUP00000168623
Takifugu rubripes (Fru) fru15839 SINFRUP00000174166
Takifugu rubripes (Fru) fru15840 SINFRUP00000176907
Gallus gallus (Gga) gga17789 ENSGALP00000019178
(UBE1L2)
Gallus gallus (Gga) gga17793 ENSGALP00000019179
Gallus gallus (Gga) gga17794 ENSGALP00000019180
Gallus gallus (Gga) gga17795 ENSGALP00000019181
Gallus gallus (Gga) gga17790 ENSGALP00000019182
Gallus gallus (Gga) gga17791 ENSGALP00000019183
Gallus gallus (Gga) gga17792 ENSGALP00000019184
Homo sapiens (Hsa) hsa24147 ENSP00000313454
(UBA6)		 A0AVT1-1
Homo sapiens (Hsa) hsa32692 ENSP00000338413
(UBA1)		 P22314
Homo sapiens (Hsa) hsa32691 ENSP00000340158
Kluyveromyces lactis (Kla) kla1164 KLLA0B14278g
Mus musculus (Mmu) mmu28754 ENSMUSP00000001989
(MGI:98890)		 Q02053
Mus musculus (Mmu) mmu20281 ENSMUSP00000035328
(MGI:1913894)		 Q8C7R4
Mus musculus (Mmu) mmu30113 ENSMUSP00000075201
Mus musculus (Mmu) mmu30143 ENSMUSP00000077638
Neurospora crassa (Ncr) ncr4245 NCU04370.2
Oryza sativa (Osa) osa1611 1889.m00188
Oryza sativa (Osa) osa60044 6554.m00150
Oryza sativa (Osa) osa73772 7129.m00132
Oryza sativa (Osa) osa73823 7129.m00183
Oryza sativa (Osa) osa75533 7235.m00155
Oryza sativa (Osa) osa77209 7313.m00141
Oryza sativa (Osa) osa77247 7313.m00179
Oryza sativa (Osa) osa74737 7339.m00161
Plasmodium falciparum (Pfa) pfa5032 PFL1245w
Rattus norvegicus (Rno) rno10231 ENSRNOP00000030667
(RGD:1308324)
Rattus norvegicus (Rno) rno30794 ENSRNOP00000033950
(RGD:1359327)		 Q5U300
Rattus norvegicus (Rno) rno30793 ENSRNOP00000034264
Saccharomyces cerevisiae (Sce) sce3883 YKL210W
(S000001693)
Schizosaccharomyces pombe (Spo) spo4954 SPBC1604.21c O94609
Yarrowia lipolytica (Yli) yli4115 YALI0E06017g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPFL1245w
GO:0005634 nucleus C
IDA
SceS000001693
SpoSPBC1604.21c
TAS
AthAt5g06460
GO:0005737 cytoplasm C
IDA
SceS000001693
SpoSPBC1604.21c
GO:0005829 cytosol C
IDA
SpoSPBC1604.21c
GO:0005886 plasma membrane C
IDA
AthAt2g30110
GO:0030425 dendrite C
IMP
DmeFBgn0023143
GO:0004839 ubiquitin activating enzyme activity F
IDA
SceS000001693
IMP
AthAt2g30110
At5g06460
ISS
AthAt5g06460
At2g30110
DmeFBgn0023143
GO:0004842 ubiquitin-protein ligase activity F
IDA
AthAt2g30110
At5g06460
NAS
DmeFBgn0023143
GO:0005515 protein binding F
IPI
MmuMGI:1913894
GO:0019780 FAT10 activating enzyme activity F
IMP
MmuMGI:1913894
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC1604.21c
GO:0006508 proteolysis P
RCA
SceS000001693
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
IMP
MmuMGI:1913894
TAS
AthAt5g06460
At2g30110
GO:0008283 cell proliferation P
IMP
DmeFBgn0023143
GO:0016319 mushroom body development P
IMP
DmeFBgn0023143
GO:0016322 neuron remodeling P
IMP
DmeFBgn0023143
GO:0016567 protein ubiquitination P
IDA
AthAt5g06460
At2g30110
SceS000001693
IMP
DmeFBgn0023143
MmuMGI:1913894
GO:0019915 lipid storage P
IDA
DmeFBgn0023143
GO:0032446 protein modification by small protein
conjugation		 P
ISS
SpoSPBC1604.21c
GO:0046578 regulation of Ras protein signal
transduction		 P
IMP
DmeFBgn0023143
GO:0046686 response to cadmium ion P
IEP
AthAt2g30110
GO:0051707 response to other organism P
IMP
AthAt2g30110

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1604.21c
(O94609)		 YKL210W
(S000001693)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000001693
SpoSPBC1604.21c
GO:0005737 cytoplasm C
IDA
SceS000001693
SpoSPBC1604.21c
GO:0005829 cytosol C
IDA
SpoSPBC1604.21c
GO:0004839 ubiquitin activating enzyme activity F
IDA
SceS000001693
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC1604.21c
GO:0006508 proteolysis P
RCA
SceS000001693
GO:0016567 protein ubiquitination P
IDA
SceS000001693
GO:0032446 protein modification by small protein
conjugation		 P
ISS
SpoSPBC1604.21c

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