YOGY Home YOGY Help

Search term: YKL216W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name URA1
SGD link S000001699
Alternative ID YKL216W
Description Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid
Synonyms YKL216W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1436 ACDHYP-

KOGs classification KOGs description
METABOLISM Dihydroorotate dehydrogenase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g23300 GI:10177819
Caenorhabditis elegans (Cel) CE14420
(WBGene00020932)		 GI:17509475 O01815
Drosophila melanogaster (Dme) 7299059 GI:17137316
Homo sapiens (Hsa) Hs16753223 GI:16753223
Saccharomyces cerevisiae (Sce) YKL216w
(S000001699)		 GI:6322633 P28272
Schizosaccharomyces pombe (Spo) SPAC57A10.12c GI:19114229 P32747


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001699
GO:0005739 mitochondrion C
IDA
AthAt5g23300
SpoSPAC57A10.12c
GO:0019898 extrinsic to membrane C
IDA
SceS000001699
GO:0004152 dihydroorotate dehydrogenase activity F
IDA
AthAt5g23300
SceS000001699
IGI
AthAt5g23300
IMP
SceS000001699
ISS
AthAt5g23300
GO:0004158 dihydroorotate oxidase activity F
IDA
SpoSPAC57A10.12c
GO:0006207 'de novo' pyrimidine base biosynthetic
process		 P
IDA
SpoSPAC57A10.12c
IMP
SceS000001699
ISS
AthAt5g23300
GO:0009220 pyrimidine ribonucleotide biosynthetic
process		 P
IDA
AthAt5g23300
IGI
AthAt5g23300

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48841

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) URA1
(S000001699)		 GI:6322633 P28272
Kluyveromyces lactis (Kla) KLLA0C19360g GI:50306203


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001699
GO:0019898 extrinsic to membrane C
IDA
SceS000001699
GO:0004152 dihydroorotate dehydrogenase activity F
IDA
SceS000001699
IMP
SceS000001699
GO:0006207 'de novo' pyrimidine base biosynthetic
process		 P
IMP
SceS000001699

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1133

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15732 ENSANGP00000016011
Arabidopsis thaliana (Ath) ath14040 At3g17810.1
Caenorhabditis elegans (Cel) cel2682 C25F6.3
(CE38489;
WBGene00016103)
Dictyostelium discoideum (Ddi) ddi11476 DDB0231100
Drosophila melanogaster (Dme) dme17114 CG2194-PB
(FBgn0016718)
Drosophila melanogaster (Dme) dme17115 CG2194-PC
(FBgn0016718)
Danio rerio (Dre) dre11017 ENSDARP00000019636
Danio rerio (Dre) dre11023 ENSDARP00000027618
(dpyd)		 Q6NYG8
Danio rerio (Dre) dre11021 ENSDARP00000040340
Escherichia coli (Eco) eco2078 16130084
Escherichia coli (Eco) eco2389 16130393
Escherichia coli (Eco) eco2789 16130789
Escherichia coli (Eco) eco3104 16131103
Escherichia coli (Eco) eco2079 49176192
Takifugu rubripes (Fru) fru20557 SINFRUP00000147476
Takifugu rubripes (Fru) fru17743 SINFRUP00000163100
Takifugu rubripes (Fru) fru17742 SINFRUP00000163102
Gallus gallus (Gga) gga22450 ENSGALP00000008827
Gallus gallus (Gga) gga22451 ENSGALP00000008828
(DPYD)
Homo sapiens (Hsa) hsa1541 ENSP00000271131
Kluyveromyces lactis (Kla) kla2063 KLLA0C19360g
Mus musculus (Mmu) mmu17470 ENSMUSP00000039429
(MGI:2139667)		 Q8CHR6
Mus musculus (Mmu) mmu17469 ENSMUSP00000070739
(MGI:1915925)		 Q3V345
Neurospora crassa (Ncr) ncr4194 NCU04318.2
Oryza sativa (Osa) osa7490 2519.m00086
Oryza sativa (Osa) osa29828 4290.m00210
Rattus norvegicus (Rno) rno16928 ENSRNOP00000023227
(RGD:621218)		 O89000
Saccharomyces cerevisiae (Sce) sce3889 YKL216W
(S000001699)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005625 soluble fraction C
ISO
MmuMGI:2139667
GO:0005737 cytoplasm C
IDA
SceS000001699
GO:0005829 cytosol C
IDA
MmuMGI:2139667
ISO
MmuMGI:2139667
GO:0009507 chloroplast C
IDA
AthAt3g17810
GO:0009536 plastid C
IDA
AthAt3g17810
GO:0019898 extrinsic to membrane C
IDA
SceS000001699
GO:0002058 uracil binding F
ISO
MmuMGI:2139667
GO:0004152 dihydroorotate dehydrogenase activity F
IDA
SceS000001699
IMP
SceS000001699
GO:0016627 oxidoreductase activity, acting on the CH-CH group
of donors		 F
ISS
AthAt3g17810
GO:0017113 dihydropyrimidine dehydrogenase (NADP+)
activity		 F
IDA
MmuMGI:2139667
IMP
AthAt3g17810
ISO
MmuMGI:2139667
GO:0042803 protein homodimerization activity F
ISO
MmuMGI:2139667
GO:0050661 NADP or NADPH binding F
ISO
MmuMGI:2139667
GO:0006207 'de novo' pyrimidine base biosynthetic
process		 P
IMP
SceS000001699
ISS
AthAt3g17810
GO:0006208 pyrimidine base catabolic process P
IDA
MmuMGI:2139667
ISO
MmuMGI:2139667
GO:0006212 uracil catabolic process P
IMP
AthAt3g17810
GO:0007584 response to nutrient P
ISO
MmuMGI:2139667
GO:0007623 circadian rhythm P
ISO
MmuMGI:2139667
GO:0019860 uracil metabolic process P
ISO
MmuMGI:2139667
GO:0042493 response to drug P
ISO
MmuMGI:2139667
GO:0043562 cellular response to nitrogen levels P
IEP
AthAt3g17810

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC57A10.12c
(P32747)		 YKL216W
(S000001699)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000001699
GO:0005739 mitochondrion C
IDA
SpoSPAC57A10.12c
GO:0019898 extrinsic to membrane C
IDA
SceS000001699
GO:0004152 dihydroorotate dehydrogenase activity F
IDA
SceS000001699
IMP
SceS000001699
GO:0004158 dihydroorotate oxidase activity F
IDA
SpoSPAC57A10.12c
GO:0006207 'de novo' pyrimidine base biosynthetic
process		 P
IDA
SpoSPAC57A10.12c
IMP
SceS000001699

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk