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Search term: YKR010C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TOF2
SGD link S000001718
Alternative ID YKR010C
Description Protein required for rDNA silencing and mitotic rDNA condensation; stimulates Cdc14p phosphatase activity and biphasic release to promote rDNA repeat segregation; required for condensin recruitment to the replication fork barrier site
Synonyms YKR010C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC25D12.02c
(O74354)
YKR010C
(S000001718)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
IDA
SceS000001718
SpoSPBC25D12.02c
GO:0005737 cytoplasm C
IDA
SpoSPBC25D12.02c
GO:0005739 mitochondrion C
IDA
SceS000001718
GO:0005819 spindle C
IDA
SpoSPBC25D12.02c
GO:0005515 protein binding F
IPI
SpoSPBC25D12.02c
GO:0019211 phosphatase activator activity F
IDA
SceS000001718
GO:0000183 chromatin silencing at rDNA P
IMP
SceS000001718
SpoSPBC25D12.02c
GO:0007000 nucleolus organization P
IGI
SceS000001718
IMP
SceS000001718
GO:0031030 negative regulation of septation initiation
signaling
P
IGI
SpoSPBC25D12.02c
GO:0034503 protein localization to nucleolar rDNA
repeats
P
IMP
SceS000001718
GO:0070550 rDNA condensation P
IMP
SceS000001718

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