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Search term: YKR090W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PXL1
SGD link S000001798
Alternative ID YKR090W
Description LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin
Synonyms YKR090W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1703 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Adaptor protein Enigma and related PDZ-LIM proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g19270 GI:15221983
Arabidopsis thaliana (Ath) At2g39830 GI:15225574
Arabidopsis thaliana (Ath) At4g36860 GI:15234545
Arabidopsis thaliana (Ath) At5g17890_2 GI:15238670
Arabidopsis thaliana (Ath) At5g66610 GI:15240017
Arabidopsis thaliana (Ath) At5g66620 GI:15240018
Arabidopsis thaliana (Ath) At5g66630_2 GI:15240045
Arabidopsis thaliana (Ath) At5g66640 GI:15240046
Caenorhabditis elegans (Cel) CE01828 GI:17552362
Caenorhabditis elegans (Cel) CE03650 GI:17542300
Caenorhabditis elegans (Cel) CE05315
(WBGene00007740)		 GI:17505729 Q18208
Caenorhabditis elegans (Cel) CE09891
(WBGene00018000)		 GI:17507103 O44778
Caenorhabditis elegans (Cel) CE16892
(WBGene00016389)		 GI:17505827 O44949
Caenorhabditis elegans (Cel) CE20175
(WBGene00012379)		 GI:17555544 Q9XXT7
Caenorhabditis elegans (Cel) CE23209 GI:17510765
Caenorhabditis elegans (Cel) CE23977 GI:17542302
Caenorhabditis elegans (Cel) CE25530
(WBGene00022030)		 GI:17510387 Q9BL58
Drosophila melanogaster (Dme) 7291703 GI:7291703
Drosophila melanogaster (Dme) 7293274 GI:7293274
Drosophila melanogaster (Dme) 7293275 GI:20129029
Drosophila melanogaster (Dme) 7298573 GI:7298573
Drosophila melanogaster (Dme) 7298768 GI:7298768
Drosophila melanogaster (Dme) 7303036 GI:7303036
Drosophila melanogaster (Dme) 7303038 GI:7303038
Homo sapiens (Hsa) Hs11496885
(PDLIM7)		 GI:11496885 Q9NR12
Homo sapiens (Hsa) Hs13994151
(PDLIM1)		 GI:13994151 O00151
Homo sapiens (Hsa) Hs18597237 GI:18597237
Homo sapiens (Hsa) Hs19923181
(PDLIM4)		 GI:19923181 P50479
Homo sapiens (Hsa) Hs21361591 GI:20562598
Homo sapiens (Hsa) Hs21361888 GI:14042747 Q8TET9
Homo sapiens (Hsa) Hs22055163 GI:22055163
Homo sapiens (Hsa) Hs4506345 GI:4506345
Homo sapiens (Hsa) Hs4758670 GI:4758670 O60711
Homo sapiens (Hsa) Hs5453714 GI:5453714
Homo sapiens (Hsa) Hs7656883 GI:7656883
Homo sapiens (Hsa) HsM11056000 GI:11056000
Homo sapiens (Hsa) HsM7706250 GI:7706250
Saccharomyces cerevisiae (Sce) YDL240w_1 GI:6319961 P35688
Saccharomyces cerevisiae (Sce) YKR090w
(S000001798)		 GI:6322943 P36166
Schizosaccharomyces pombe (Spo) SPBC3F6.05_1 GI:19113535 O43052
Schizosaccharomyces pombe (Spo) SPBC4F6.12 GI:19112904 O74398


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000001798
GO:0005575 cellular_component C
ND
AthAt5g66610
At5g66640
At5g17890
GO:0005634 nucleus C
IDA
SpoSPBC3F6.05
GO:0005737 cytoplasm C
IDA
SceS000001798
ISS
SpoSPBC3F6.05
GO:0005826 actomyosin contractile ring C
IDA
SpoSPBC4F6.12
GO:0005829 cytosol C
IDA
SpoSPBC3F6.05
GO:0005886 plasma membrane C
IDA
AthAt4g36860
GO:0005925 focal adhesion C
IDA
HsaPDLIM7
GO:0005933 cellular bud C
IDA
SceS000001798
GO:0005934 cellular bud tip C
IDA
SceS000001798
GO:0005935 cellular bud neck C
IDA
SceS000001798
GO:0015629 actin cytoskeleton C
IDA
HsaPDLIM7
GO:0030054 cell junction C
IDA
HsaPDLIM7
GO:0031097 medial cortex C
IDA
SpoSPBC4F6.12
GO:0032153 cell division site C
IDA
SpoSPBC3F6.05
SPBC4F6.12
GO:0043332 mating projection tip C
IDA
SceS000001798
GO:0051286 cell tip C
IDA
SpoSPBC3F6.05
GO:0003674 molecular_function F
ND
AthAt5g66640
GO:0005100 Rho GTPase activator activity F
ISS
SpoSPBC3F6.05
GO:0005515 protein binding F
IPI
HsaPDLIM7
PDLIM4
SpoSPBC4F6.12
ISS
SceS000001798
GO:0043130 ubiquitin binding F
IPI
AthAt1g19270
GO:0000003 reproduction P
RCA
SceS000001798
GO:0000915 cytokinesis, actomyosin contractile ring
assembly		 P
IGI
SpoSPBC4F6.12
IMP
SpoSPBC4F6.12
GO:0000916 contractile ring contraction involved in cell
cycle cytokinesis		 P
IMP
SpoSPBC4F6.12
GO:0000917 barrier septum formation P
IMP
SpoSPBC3F6.05
GO:0006898 receptor-mediated endocytosis P
TAS
HsaPDLIM7
GO:0006952 defense response P
IMP
AthAt5g17890
ISS
AthAt5g17890
GO:0006979 response to oxidative stress P
TAS
HsaPDLIM1
GO:0008150 biological_process P
ND
AthAt5g66640
GO:0008360 regulation of cell shape P
IMP
SpoSPBC3F6.05
GO:0009272 fungal-type cell wall biogenesis P
IMP
SpoSPBC3F6.05
GO:0009409 response to cold P
IMP
AthAt5g17890
GO:0030011 maintenance of cell polarity P
IMP
SceS000001798
GO:0030036 actin cytoskeleton organization P
IMP
SpoSPBC3F6.05
GO:0032319 regulation of Rho GTPase activity P
ISS
SpoSPBC3F6.05
GO:0032465 regulation of cytokinesis P
IMP
SpoSPBC4F6.12
GO:0034259 negative regulation of Rho GTPase
activity		 P
IMP
SpoSPBC4F6.12
GO:0034613 cellular protein localization P
ISS
SpoSPBC4F6.12
GO:0035023 regulation of Rho protein signal
transduction		 P
IGI
SpoSPBC4F6.12
GO:0035024 negative regulation of Rho protein signal
transduction		 P
IGI
SpoSPBC4F6.12
GO:0045132 meiotic chromosome segregation P
IMP
CelWBGene00016389
GO:0046621 negative regulation of organ growth P
IMP
AthAt1g19270
GO:0048317 seed morphogenesis P
IMP
AthAt1g19270
GO:0048482 ovule morphogenesis P
IMP
AthAt1g19270
GO:0051181 cofactor transport P
RCA
SceS000001798
GO:0051301 cell division P
RCA
SceS000001798
GO:0051666 actin cortical patch localization P
IMP
SpoSPBC3F6.05

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48871

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) PXL1
(S000001798)		 GI:6322943 P36166
Kluyveromyces lactis (Kla) KLLA0E13167g GI:50309073
Eremothecium gossypii (Ego) AGOS_ADR232W GI:45188105


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000001798
GO:0005737 cytoplasm C
IDA
SceS000001798
GO:0005933 cellular bud C
IDA
SceS000001798
GO:0005934 cellular bud tip C
IDA
SceS000001798
GO:0005935 cellular bud neck C
IDA
SceS000001798
GO:0043332 mating projection tip C
IDA
SceS000001798
GO:0005515 protein binding F
ISS
SceS000001798
GO:0000003 reproduction P
RCA
SceS000001798
GO:0030011 maintenance of cell polarity P
IMP
SceS000001798
GO:0051181 cofactor transport P
RCA
SceS000001798
GO:0051301 cell division P
RCA
SceS000001798

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_9360

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1973 ADR232W
Candida glabrata (Cgl) cgl1727 CAGL0G02387g
Cryptococcus neoformans (Cne) cne4925 186.m03833
Dictyostelium discoideum (Ddi) ddi2448 DDB0217814
Debaryomyces hansenii (Dha) dha3486 DEHA0E05610g
Debaryomyces hansenii (Dha) dha3487 DEHA0E05632g
Homo sapiens (Hsa) hsa8293 ENSP00000331829
(PXN)		 Q9BTK0
Kluyveromyces lactis (Kla) kla3541 KLLA0E13167g
Neurospora crassa (Ncr) ncr6484 NCU06668.2
Saccharomyces cerevisiae (Sce) sce3990 YKR090W
(S000001798)
Yarrowia lipolytica (Yli) yli3495 YALI0D18898g