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Search term: YKR095W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MLP1
SGD link S000001803
Alternative ID YKR095W
Description Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs
Synonyms YKR095W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4674 A-DHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved coiled-coil protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g79280 GI:15219336
Drosophila melanogaster (Dme) 7303561 GI:7303561 A1Z8P9
Homo sapiens (Hsa) Hs22044282 GI:22044282
Homo sapiens (Hsa) Hs4507659 GI:4507659
Saccharomyces cerevisiae (Sce) YIL149c
(S000001411)		 GI:6322042 P40457
Saccharomyces cerevisiae (Sce) YKR095w
(S000001803)		 GI:6322948 Q02455
Schizosaccharomyces pombe (Spo) SPAC1486.04c GI:19115004 Q9UTK5
Schizosaccharomyces pombe (Spo) SPAC1F3.06c GI:19113921 Q10411
Schizosaccharomyces pombe (Spo) SPCC162.08c GI:19075736 O74424


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC162.08c
SPAC1486.04c
GO:0005635 nuclear envelope C
IDA
AthAt1g79280
SceS000001803
S000001411
GO:0005643 nuclear pore C
RCA
SceS000001411
S000001803
TAS
SpoSPCC162.08c
GO:0005654 nucleoplasm C
IDA
SceS000001411
S000001803
GO:0005730 nucleolus C
IDA
AthAt1g79280
GO:0005737 cytoplasm C
IDA
SpoSPCC162.08c
GO:0005739 mitochondrion C
IDA
SceS000001411
GO:0005816 spindle pole body C
IDA
SceS000001803
S000001411
SpoSPAC1F3.06c
IPI
SceS000001411
GO:0005829 cytosol C
IDA
AthAt1g79280
GO:0009507 chloroplast C
IDA
AthAt1g79280
GO:0016021 integral to membrane C
RCA
SceS000001803
S000001411
GO:0030529 ribonucleoprotein complex C
IPI
SceS000001803
S000001411
GO:0031097 medial cortex C
IDA
SpoSPAC1486.04c
GO:0031224 intrinsic to membrane C
RCA
SceS000001803
S000001411
GO:0031965 nuclear membrane C
IDA
SpoSPCC162.08c
GO:0032153 cell division site C
IDA
SpoSPAC1486.04c
GO:0034399 nuclear periphery C
IDA
SpoSPCC162.08c
GO:0046930 pore complex C
RCA
SceS000001411
S000001803
GO:0003674 molecular_function F
ND
AthAt1g79280
SpoSPAC1486.04c
GO:0005515 protein binding F
IPI
SpoSPAC1F3.06c
GO:0043021 ribonucleoprotein binding F
IGI
SceS000001803
S000001411
IPI
SceS000001803
S000001411
ISS
SpoSPCC162.08c
GO:0006406 mRNA export from nucleus P
IGI
SceS000001803
S000001411
IMP
SpoSPCC162.08c
IPI
SceS000001803
S000001411
GO:0006606 protein import into nucleus P
IGI
SceS000001411
S000001803
ISS
SpoSPCC162.08c
GO:0006611 protein export from nucleus P
RCA
SceS000001411
GO:0006997 nucleus organization P
RCA
SceS000001411
GO:0006999 nuclear pore organization P
RCA
SceS000001411
GO:0009910 negative regulation of flower development P
IMP
AthAt1g79280
GO:0016973 poly(A)+ mRNA export from nucleus P
IMP
AthAt1g79280
GO:0030476 ascospore wall assembly P
IMP
SpoSPAC1F3.06c
GO:0031322 ascospore-type prospore-specific spindle pole body
modification		 P
IMP
SpoSPAC1F3.06c
GO:0033205 cell cycle cytokinesis P
IMP
SpoSPAC1486.04c
GO:0033234 negative regulation of protein
sumoylation		 P
IMP
AthAt1g79280
GO:0034613 cellular protein localization P
IGI
SpoSPAC1F3.06c
GO:0045449 regulation of transcription P
IEP
SceS000001411
IGI
SceS000001411
GO:0048443 stamen development P
IMP
AthAt1g79280
GO:0051237 maintenance of RNA location P
IMP
SceS000001803
GO:0051300 spindle pole body organization P
IMP
SceS000001411
GO:0051301 cell division P
IMP
SpoSPCC162.08c
GO:0071048 nuclear retention of unspliced pre-mRNA at the
site of transcription		 P
IGI
SceS000001803
IMP
SceS000001803
GO:0090203 transcriptional activation by promoter-terminator
looping		 P
IMP
SceS000001803
GO:0090204 protein localization to nuclear
pore		 P
IMP
SceS000001803

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
37753

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) TPR GI:114155142
Pan troglodytes (Ptr) TPR GI:114568431
Canis familiaris (Cfa) TPR GI:73961225
Mus musculus (Mmu) Tpr
(MGI:1922066)		 GI:27477057 Q05CS8
Rattus norvegicus (Rno) Tpr
(RGD:1310664)		 GI:109498005
Gallus gallus (Gga) TPR GI:118094253
Drosophila melanogaster (Dme) Mtor
(FBgn0013756)		 GI:24652825
Anopheles gambiae (Aga) AgaP_AGAP001754 GI:158301661
Schizosaccharomyces pombe (Spo) nup211
(SPCC162.08c)		 GI:19075736 O74424
Saccharomyces cerevisiae (Sce) MLP1
(S000001803)		 GI:6322948 Q02455
Kluyveromyces lactis (Kla) KLLA0A00594g GI:50302181
Eremothecium gossypii (Ego) AGOS_AFR286W GI:45198804
Magnaporthe grisea (Mgr) MGG_00594 GI:39974519
Neurospora crassa (Ncr) NCU04059.1 GI:32405530
Arabidopsis thaliana (Ath) NUA GI:186496370
Oryza sativa (Osa) Os02g0741500 GI:115448605


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
HsaTPR
GO:0005634 nucleus C
IDA
DmeFBgn0013756
SpoSPCC162.08c
GO:0005635 nuclear envelope C
IDA
AthNUA
HsaTPR
MmuMGI:1922066
SceS000001803
GO:0005643 nuclear pore C
IDA
DmeFBgn0013756
HsaTPR
NAS
DmeFBgn0013756
RCA
SceS000001803
TAS
SpoSPCC162.08c
GO:0005654 nucleoplasm C
EXP
HsaTPR
IDA
SceS000001803
GO:0005730 nucleolus C
IDA
AthNUA
GO:0005737 cytoplasm C
IDA
SpoSPCC162.08c
GO:0005816 spindle pole body C
IDA
SceS000001803
GO:0005829 cytosol C
IDA
AthNUA
GO:0009507 chloroplast C
IDA
AthNUA
GO:0016021 integral to membrane C
RCA
SceS000001803
GO:0030529 ribonucleoprotein complex C
IPI
SceS000001803
GO:0031224 intrinsic to membrane C
RCA
SceS000001803
GO:0031965 nuclear membrane C
IDA
SpoSPCC162.08c
GO:0034399 nuclear periphery C
IDA
SpoSPCC162.08c
GO:0046930 pore complex C
RCA
SceS000001803
GO:0051233 spindle midzone C
IDA
DmeFBgn0013756
GO:0003674 molecular_function F
ND
AthNUA
MmuMGI:1922066
GO:0005515 protein binding F
IPI
HsaTPR
GO:0043021 ribonucleoprotein binding F
IGI
SceS000001803
IPI
SceS000001803
ISS
SpoSPCC162.08c
GO:0006406 mRNA export from nucleus P
IGI
SceS000001803
IMP
SpoSPCC162.08c
IPI
SceS000001803
GO:0006606 protein import into nucleus P
IGI
SceS000001803
ISS
SpoSPCC162.08c
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IMP
HsaTPR
GO:0008150 biological_process P
ND
MmuMGI:1922066
GO:0009910 negative regulation of flower development P
IMP
AthNUA
GO:0016973 poly(A)+ mRNA export from nucleus P
IMP
AthNUA
GO:0033234 negative regulation of protein
sumoylation		 P
IMP
AthNUA
GO:0048443 stamen development P
IMP
AthNUA
GO:0051225 spindle assembly P
IDA
DmeFBgn0013756
GO:0051237 maintenance of RNA location P
IMP
SceS000001803
GO:0051301 cell division P
IMP
SpoSPCC162.08c
GO:0071048 nuclear retention of unspliced pre-mRNA at the
site of transcription		 P
IGI
SceS000001803
IMP
SceS000001803
GO:0090203 transcriptional activation by promoter-terminator
looping		 P
IMP
SceS000001803
GO:0090204 protein localization to nuclear
pore		 P
IMP
SceS000001803

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3412

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3872 ENSANGP00000012828
Ashbya gossypii (Ago) ago3478 AFR286W
Arabidopsis thaliana (Ath) ath7289 At1g79280.1
Caenorhabditis elegans (Cel) cel13550 R07G3.3a
(CE37543;
WBGene00019940)
Caenorhabditis elegans (Cel) cel13551 R07G3.3b
(CE37544)
Candida glabrata (Cgl) cgl1732 CAGL0G02497g
Cryptococcus neoformans (Cne) cne2654 183.m01589
Dictyostelium discoideum (Ddi) ddi7319 DDB0187764
Debaryomyces hansenii (Dha) dha4117 DEHA0E19811g
Drosophila melanogaster (Dme) dme4554 CG8274-PA
(FBgn0013756)
Danio rerio (Dre) dre12849 ENSDARP00000019846
(tpr)		 Q5RI09
Takifugu rubripes (Fru) fru29764 SINFRUP00000167291
Takifugu rubripes (Fru) fru29763 SINFRUP00000174869
Gallus gallus (Gga) gga22399 ENSGALP00000008171
(TPR)
Gallus gallus (Gga) gga22400 ENSGALP00000008172
Homo sapiens (Hsa) hsa2752 ENSP00000264142
Kluyveromyces lactis (Kla) kla21 KLLA0A00594g
Mus musculus (Mmu) mmu1200 ENSMUSP00000006162
Mus musculus (Mmu) mmu1199 ENSMUSP00000066479
(MGI:1922066)		 Q05CS8
Neurospora crassa (Ncr) ncr3935 NCU04059.2
Oryza sativa (Osa) osa78335 7489.m00108
Rattus norvegicus (Rno) rno9232 ENSRNOP00000003318
(RGD:1310664)
Saccharomyces cerevisiae (Sce) sce3995 YKR095W
(S000001803)
Schizosaccharomyces pombe (Spo) spo396 SPCC162.08c O74424
Yarrowia lipolytica (Yli) yli6205 YALI0F20526g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
DmeFBgn0013756
SpoSPCC162.08c
GO:0005635 nuclear envelope C
IDA
AthAt1g79280
MmuMGI:1922066
SceS000001803
GO:0005643 nuclear pore C
IDA
DmeFBgn0013756
NAS
DmeFBgn0013756
RCA
SceS000001803
TAS
SpoSPCC162.08c
GO:0005654 nucleoplasm C
IDA
SceS000001803
GO:0005730 nucleolus C
IDA
AthAt1g79280
GO:0005737 cytoplasm C
IDA
SpoSPCC162.08c
GO:0005816 spindle pole body C
IDA
SceS000001803
GO:0005829 cytosol C
IDA
AthAt1g79280
GO:0009507 chloroplast C
IDA
AthAt1g79280
GO:0016021 integral to membrane C
RCA
SceS000001803
GO:0030529 ribonucleoprotein complex C
IPI
SceS000001803
GO:0031224 intrinsic to membrane C
RCA
SceS000001803
GO:0031965 nuclear membrane C
IDA
SpoSPCC162.08c
GO:0034399 nuclear periphery C
IDA
SpoSPCC162.08c
GO:0046930 pore complex C
RCA
SceS000001803
GO:0051233 spindle midzone C
IDA
DmeFBgn0013756
GO:0003674 molecular_function F
ND
AthAt1g79280
MmuMGI:1922066
GO:0043021 ribonucleoprotein binding F
IGI
SceS000001803
IPI
SceS000001803
ISS
SpoSPCC162.08c
GO:0000003 reproduction P
IMP
CelWBGene00019940
GO:0002119 nematode larval development P
IMP
CelWBGene00019940
GO:0006406 mRNA export from nucleus P
IGI
SceS000001803
IMP
SpoSPCC162.08c
IPI
SceS000001803
GO:0006606 protein import into nucleus P
IGI
SceS000001803
ISS
SpoSPCC162.08c
GO:0008150 biological_process P
ND
MmuMGI:1922066
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019940
GO:0009910 negative regulation of flower development P
IMP
AthAt1g79280
GO:0016973 poly(A)+ mRNA export from nucleus P
IMP
AthAt1g79280
GO:0033234 negative regulation of protein
sumoylation		 P
IMP
AthAt1g79280
GO:0040007 growth P
IMP
CelWBGene00019940
GO:0040011 locomotion P
IMP
CelWBGene00019940
GO:0040015 negative regulation of multicellular organism
growth		 P
IMP
CelWBGene00019940
GO:0048443 stamen development P
IMP
AthAt1g79280
GO:0051225 spindle assembly P
IDA
DmeFBgn0013756
GO:0051237 maintenance of RNA location P
IMP
SceS000001803
GO:0051301 cell division P
IMP
SpoSPCC162.08c
GO:0071048 nuclear retention of unspliced pre-mRNA at the
site of transcription		 P
IGI
SceS000001803
IMP
SceS000001803
GO:0090203 transcriptional activation by promoter-terminator
looping		 P
IMP
SceS000001803
GO:0090204 protein localization to nuclear
pore		 P
IMP
SceS000001803

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC162.08c
(O74424)		 YKR095W
(S000001803)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC162.08c
GO:0005635 nuclear envelope C
IDA
SceS000001803
GO:0005643 nuclear pore C
RCA
SceS000001803
TAS
SpoSPCC162.08c
GO:0005654 nucleoplasm C
IDA
SceS000001803
GO:0005737 cytoplasm C
IDA
SpoSPCC162.08c
GO:0005816 spindle pole body C
IDA
SceS000001803
GO:0016021 integral to membrane C
RCA
SceS000001803
GO:0030529 ribonucleoprotein complex C
IPI
SceS000001803
GO:0031224 intrinsic to membrane C
RCA
SceS000001803
GO:0031965 nuclear membrane C
IDA
SpoSPCC162.08c
GO:0034399 nuclear periphery C
IDA
SpoSPCC162.08c
GO:0046930 pore complex C
RCA
SceS000001803
GO:0043021 ribonucleoprotein binding F
IGI
SceS000001803
IPI
SceS000001803
ISS
SpoSPCC162.08c
GO:0006406 mRNA export from nucleus P
IGI
SceS000001803
IMP
SpoSPCC162.08c
IPI
SceS000001803
GO:0006606 protein import into nucleus P
IGI
SceS000001803
ISS
SpoSPCC162.08c
GO:0051237 maintenance of RNA location P
IMP
SceS000001803
GO:0051301 cell division P
IMP
SpoSPCC162.08c
GO:0071048 nuclear retention of unspliced pre-mRNA at the
site of transcription		 P
IGI
SceS000001803
IMP
SceS000001803
GO:0090203 transcriptional activation by promoter-terminator
looping		 P
IMP
SceS000001803
GO:0090204 protein localization to nuclear
pore		 P
IMP
SceS000001803

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GO info in one table:

s.khadayate@ucl.ac.uk