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Search term: YLL036C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRP19
SGD link S000003959
Alternative ID YLL036C
Description Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases
Synonyms YLL036C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0289 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED mRNA splicing factor

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g04510 GI:15219739
Arabidopsis thaliana (Ath) At2g33340 GI:15225837
Caenorhabditis elegans (Cel) CE02043 GI:17555002
Drosophila melanogaster (Dme) 7302603
(FBgn0013969)		 GI:17647459 Q7KLW9
Homo sapiens (Hsa) Hs7657381
(PRPF19)		 GI:7657381 Q9UMS4
Saccharomyces cerevisiae (Sce) YLL036c
(S000003959)		 GI:6322992 P32523
Schizosaccharomyces pombe (Spo) SPAC29A4.08c GI:19115786 O14011
Arabidopsis thaliana (Ath) At1g04510 GI:15219739
Arabidopsis thaliana (Ath) At2g33340 GI:15225837
Caenorhabditis elegans (Cel) CE02043 GI:17555002
Drosophila melanogaster (Dme) 7302603
(FBgn0013969)		 GI:17647459 Q7KLW9
Homo sapiens (Hsa) Hs7657381
(PRPF19)		 GI:7657381 Q9UMS4
Saccharomyces cerevisiae (Sce) YLL036c
(S000003959)		 GI:6322992 P32523
Schizosaccharomyces pombe (Spo) SPAC29A4.08c GI:19115786 O14011
Arabidopsis thaliana (Ath) At1g04510 GI:15219739
Arabidopsis thaliana (Ath) At2g33340 GI:15225837
Caenorhabditis elegans (Cel) CE02043 GI:17555002
Drosophila melanogaster (Dme) 7302603
(FBgn0013969)		 GI:17647459 Q7KLW9
Homo sapiens (Hsa) Hs7657381
(PRPF19)		 GI:7657381 Q9UMS4
Saccharomyces cerevisiae (Sce) YLL036c
(S000003959)		 GI:6322992 P32523
Schizosaccharomyces pombe (Spo) SPAC29A4.08c GI:19115786 O14011


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
TAS
SpoSPAC29A4.08c
GO:0000974 Prp19 complex C
IDA
SceS000003959
GO:0005618 cell wall C
IDA
AthAt2g33340
GO:0005634 nucleus C
IDA
AthAt1g04510
HsaPRPF19
SceS000003959
SpoSPAC29A4.08c
GO:0005635 nuclear envelope C
IDA
SpoSPAC29A4.08c
GO:0005681 spliceosomal complex C
TAS
SpoSPAC29A4.08c
GO:0005682 U5 snRNP C
RCA
SceS000003959
GO:0005685 U1 snRNP C
RCA
SceS000003959
GO:0005686 U2 snRNP C
RCA
SceS000003959
GO:0005730 nucleolus C
IDA
AthAt1g04510
GO:0005737 cytoplasm C
IDA
HsaPRPF19
SceS000003959
SpoSPAC29A4.08c
ISS
SpoSPAC29A4.08c
GO:0005739 mitochondrion C
IDA
SceS000003959
GO:0005829 cytosol C
IDA
SpoSPAC29A4.08c
GO:0009507 chloroplast C
IDA
AthAt2g33340
GO:0016607 nuclear speck C
IDA
HsaPRPF19
GO:0046540 U4/U6 x U5 tri-snRNP complex C
RCA
SceS000003959
GO:0071006 U2-type catalytic step 1 spliceosome C
IDA
SceS000003959
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt2g33340
At1g04510
GO:0000166 nucleotide binding F
ISS
AthAt2g33340
At1g04510
GO:0000384 first spliceosomal transesterification
activity		 F
IC
SceS000003959
GO:0003723 RNA binding F
RCA
SceS000003959
GO:0004842 ubiquitin-protein ligase activity F
IDA
HsaPRPF19
SceS000003959
IMP
SceS000003959
TAS
SpoSPAC29A4.08c
GO:0005515 protein binding F
IPI
HsaPRPF19
SpoSPAC29A4.08c
GO:0034450 ubiquitin-ubiquitin ligase activity F
IDA
HsaPRPF19
GO:0042802 identical protein binding F
IPI
HsaPRPF19
GO:0000209 protein polyubiquitination P
IDA
HsaPRPF19
GO:0000245 spliceosome assembly P
IMP
HsaPRPF19
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IMP
SceS000003959
GO:0000398 nuclear mRNA splicing, via spliceosome P
TAS
SpoSPAC29A4.08c
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
SpoSPAC29A4.08c
GO:0016071 mRNA metabolic process P
RCA
SceS000003959
GO:0016567 protein ubiquitination P
TAS
SpoSPAC29A4.08c
GO:0022618 ribonucleoprotein complex assembly P
RCA
SceS000003959
GO:0034622 cellular macromolecular complex
assembly		 P
RCA
SceS000003959
GO:0042742 defense response to bacterium P
IGI
AthAt1g04510
At2g33340
GO:0046686 response to cadmium ion P
IEP
AthAt1g04510

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68823

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) PRP19
(S000003959)		 GI:6322992 P32523
Kluyveromyces lactis (Kla) KLLA0D03883g GI:50306529
Eremothecium gossypii (Ego) AGOS_ACL060C GI:45185628


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000974 Prp19 complex C
IDA
SceS000003959
GO:0005634 nucleus C
IDA
SceS000003959
GO:0005682 U5 snRNP C
RCA
SceS000003959
GO:0005685 U1 snRNP C
RCA
SceS000003959
GO:0005686 U2 snRNP C
RCA
SceS000003959
GO:0005737 cytoplasm C
IDA
SceS000003959
GO:0005739 mitochondrion C
IDA
SceS000003959
GO:0046540 U4/U6 x U5 tri-snRNP complex C
RCA
SceS000003959
GO:0071006 U2-type catalytic step 1 spliceosome C
IDA
SceS000003959
GO:0000384 first spliceosomal transesterification
activity		 F
IC
SceS000003959
GO:0003723 RNA binding F
RCA
SceS000003959
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000003959
IMP
SceS000003959
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IMP
SceS000003959
GO:0016071 mRNA metabolic process P
RCA
SceS000003959
GO:0022618 ribonucleoprotein complex assembly P
RCA
SceS000003959
GO:0034622 cellular macromolecular complex
assembly		 P
RCA
SceS000003959

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2150

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2663 ENSANGP00000016070
Ashbya gossypii (Ago) ago989 ACL060C
Arabidopsis thaliana (Ath) ath395 At1g04510.1
Arabidopsis thaliana (Ath) ath10363 At2g33340.1
Arabidopsis thaliana (Ath) ath10364 At2g33340.2
Caenorhabditis elegans (Cel) cel15233 T10F2.4
(CE38104;
WBGene00020423)
Candida glabrata (Cgl) cgl781 CAGL0D02772g
Cryptococcus neoformans (Cne) cne5366 179.m00218
Dictyostelium discoideum (Ddi) ddi4047 DDB0168276
Debaryomyces hansenii (Dha) dha4541 DEHA0F03454g
Drosophila melanogaster (Dme) dme5873 CG5519-PA
(FBgn0013969)
Danio rerio (Dre) dre5054 ENSDARP00000019741
(prp19)		 Q7ZV92
Takifugu rubripes (Fru) fru3751 SINFRUP00000144657
Takifugu rubripes (Fru) fru3750 SINFRUP00000170574
Takifugu rubripes (Fru) fru3752 SINFRUP00000171157
Gallus gallus (Gga) gga26891 ENSGALP00000022524
Gallus gallus (Gga) gga26892 ENSGALP00000022525
(PRPF19)		 Q5ZMA2
Homo sapiens (Hsa) hsa5726 ENSP00000227524
(PRPF19)		 Q9UMS4
Kluyveromyces lactis (Kla) kla2237 KLLA0D03883g
Mus musculus (Mmu) mmu13344 ENSMUSP00000025642
(MGI:106247)		 Q99KP6-2
Neurospora crassa (Ncr) ncr5535 NCU05696.2
Oryza sativa (Osa) osa634 873.m00160
Plasmodium falciparum (Pfa) pfa2738 PFC0365w
Rattus norvegicus (Rno) rno3733 ENSRNOP00000028373
(RGD:708496)		 Q9JMJ4
Saccharomyces cerevisiae (Sce) sce4046 YLL036C
(S000003959)
Schizosaccharomyces pombe (Spo) spo1688 SPAC29A4.08c O14011
Yarrowia lipolytica (Yli) yli1879 YALI0C03982g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
TAS
SpoSPAC29A4.08c
GO:0000974 Prp19 complex C
IDA
SceS000003959
GO:0005618 cell wall C
IDA
AthAt2g33340
GO:0005634 nucleus C
IDA
AthAt1g04510
MmuMGI:106247
SceS000003959
SpoSPAC29A4.08c
ISA
MmuMGI:106247
ISO
MmuMGI:106247
GO:0005635 nuclear envelope C
IDA
SpoSPAC29A4.08c
GO:0005681 spliceosomal complex C
ISA
MmuMGI:106247
TAS
SpoSPAC29A4.08c
GO:0005682 U5 snRNP C
RCA
SceS000003959
GO:0005685 U1 snRNP C
RCA
SceS000003959
GO:0005686 U2 snRNP C
RCA
SceS000003959
GO:0005730 nucleolus C
IDA
AthAt1g04510
GO:0005737 cytoplasm C
IDA
MmuMGI:106247
SceS000003959
SpoSPAC29A4.08c
ISO
MmuMGI:106247
ISS
SpoSPAC29A4.08c
GO:0005739 mitochondrion C
IDA
SceS000003959
GO:0005811 lipid particle C
IDA
MmuMGI:106247
GO:0005829 cytosol C
IDA
SpoSPAC29A4.08c
GO:0009507 chloroplast C
IDA
AthAt2g33340
GO:0016363 nuclear matrix C
ISS
PfaPFC0365w
GO:0046540 U4/U6 x U5 tri-snRNP complex C
RCA
SceS000003959
GO:0071006 U2-type catalytic step 1 spliceosome C
IDA
SceS000003959
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt2g33340
At1g04510
GO:0000166 nucleotide binding F
ISS
AthAt2g33340
At1g04510
GO:0000384 first spliceosomal transesterification
activity		 F
IC
SceS000003959
GO:0003723 RNA binding F
RCA
SceS000003959
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000003959
IMP
SceS000003959
ISO
MmuMGI:106247
TAS
SpoSPAC29A4.08c
GO:0005515 protein binding F
IPI
MmuMGI:106247
SpoSPAC29A4.08c
GO:0034450 ubiquitin-ubiquitin ligase activity F
ISO
MmuMGI:106247
GO:0000003 reproduction P
IMP
CelWBGene00020423
GO:0000209 protein polyubiquitination P
ISO
MmuMGI:106247
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IMP
SceS000003959
GO:0000398 nuclear mRNA splicing, via spliceosome P
TAS
SpoSPAC29A4.08c
GO:0001833 inner cell mass cell proliferation P
IMP
MmuMGI:106247
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00020423
GO:0002119 nematode larval development P
IMP
CelWBGene00020423
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
SpoSPAC29A4.08c
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00020423
GO:0008610 lipid biosynthetic process P
IDA
MmuMGI:106247
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00020423
GO:0016071 mRNA metabolic process P
RCA
SceS000003959
GO:0016567 protein ubiquitination P
TAS
SpoSPAC29A4.08c
GO:0022618 ribonucleoprotein complex assembly P
RCA
SceS000003959
GO:0034622 cellular macromolecular complex
assembly		 P
RCA
SceS000003959
GO:0040002 collagen and cuticulin-based cuticle
development		 P
IMP
CelWBGene00020423
GO:0040007 growth P
IMP
CelWBGene00020423
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00020423
GO:0040011 locomotion P
IMP
CelWBGene00020423
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00020423
GO:0042742 defense response to bacterium P
IGI
AthAt1g04510
At2g33340
GO:0045665 negative regulation of neuron differentiation P
IDA
MmuMGI:106247
GO:0045666 positive regulation of neuron differentiation P
ISA
MmuMGI:106247
GO:0046686 response to cadmium ion P
IEP
AthAt1g04510
GO:0048711 positive regulation of astrocyte
differentiation		 P
IDA
MmuMGI:106247

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC29A4.08c
(O14011)		 YLL036C
(S000003959)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
TAS
SpoSPAC29A4.08c
GO:0000974 Prp19 complex C
IDA
SceS000003959
GO:0005634 nucleus C
IDA
SceS000003959
SpoSPAC29A4.08c
GO:0005635 nuclear envelope C
IDA
SpoSPAC29A4.08c
GO:0005681 spliceosomal complex C
TAS
SpoSPAC29A4.08c
GO:0005682 U5 snRNP C
RCA
SceS000003959
GO:0005685 U1 snRNP C
RCA
SceS000003959
GO:0005686 U2 snRNP C
RCA
SceS000003959
GO:0005737 cytoplasm C
IDA
SceS000003959
SpoSPAC29A4.08c
ISS
SpoSPAC29A4.08c
GO:0005739 mitochondrion C
IDA
SceS000003959
GO:0005829 cytosol C
IDA
SpoSPAC29A4.08c
GO:0046540 U4/U6 x U5 tri-snRNP complex C
RCA
SceS000003959
GO:0071006 U2-type catalytic step 1 spliceosome C
IDA
SceS000003959
GO:0000384 first spliceosomal transesterification
activity		 F
IC
SceS000003959
GO:0003723 RNA binding F
RCA
SceS000003959
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000003959
IMP
SceS000003959
TAS
SpoSPAC29A4.08c
GO:0005515 protein binding F
IPI
SpoSPAC29A4.08c
GO:0000349 generation of catalytic spliceosome for first
transesterification step		 P
IMP
SceS000003959
GO:0000398 nuclear mRNA splicing, via spliceosome P
TAS
SpoSPAC29A4.08c
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
ISS
SpoSPAC29A4.08c
GO:0016071 mRNA metabolic process P
RCA
SceS000003959
GO:0016567 protein ubiquitination P
TAS
SpoSPAC29A4.08c
GO:0022618 ribonucleoprotein complex assembly P
RCA
SceS000003959
GO:0034622 cellular macromolecular complex
assembly		 P
RCA
SceS000003959

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GO info in one table:

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