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Search term: YLL040C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name VPS13
SGD link S000003963
Alternative ID YLL040C
Description Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention
Synonyms YLL040C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1809 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Vacuolar protein sorting-associated protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g47400 GI:15220189
Arabidopsis thaliana (Ath) At1g48090 GI:12323094
Arabidopsis thaliana (Ath) At3g50380 GI:15229738
Arabidopsis thaliana (Ath) At4g17110 GI:15235973
Arabidopsis thaliana (Ath) At4g17120 GI:15235975
Arabidopsis thaliana (Ath) At4g17130 GI:15235977
Arabidopsis thaliana (Ath) At4g17140 GI:15235978
Caenorhabditis elegans (Cel) CE13443
(WBGene00011629)
GI:17508963
Drosophila melanogaster (Dme) 7301869 GI:7301869
Drosophila melanogaster (Dme) 7304192 GI:7304192
Homo sapiens (Hsa) Hs15619008 GI:15619008 Q9H995
Homo sapiens (Hsa) Hs15619010 GI:15619010
Homo sapiens (Hsa) Hs20550856 GI:20550856
Homo sapiens (Hsa) Hs22048785 GI:22048785
Homo sapiens (Hsa) Hs8922394 GI:8922394
Homo sapiens (Hsa) Hs8923139 GI:8923139
Homo sapiens (Hsa) Hs8923545 GI:8923545
Saccharomyces cerevisiae (Sce) YLL040c
(S000003963)
GI:6322988 Q07878
Schizosaccharomyces pombe (Spo) SPBC16C6.02c GI:19113592 O42926
Schizosaccharomyces pombe (Spo) SPBC21C3.01c GI:19113373 P87319
Schizosaccharomyces pombe (Spo) SPBC31F10.18c GI:19113372
Encephalitozoon cuniculi (Ecu) ECU04g0690 GI:19074146 Q8SS51


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g47400
GO:0005739 mitochondrion C
IDA
SceS000003963
GO:0005768 endosome C
IDA
SceS000003963
ISS
SpoSPBC21C3.01c
SPBC16C6.02c
GO:0005773 vacuole C
IDA
AthAt4g17140
GO:0005829 cytosol C
IDA
SpoSPBC21C3.01c
GO:0009507 chloroplast C
IDA
AthAt1g48090
GO:0019898 extrinsic to membrane C
IDA
SceS000003963
GO:0003674 molecular_function F
ND
AthAt4g17140
At1g47400
SceS000003963
SpoSPBC16C6.02c
SPBC21C3.01c
GO:0035091 phosphoinositide binding F
ISS
AthAt1g48090
GO:0006886 intracellular protein transport P
IC
SpoSPBC16C6.02c
SPBC21C3.01c
GO:0007039 vacuolar protein catabolic process P
IMP
SceS000003963
RCA
SceS000003963
GO:0007165 signal transduction P
ISS
AthAt1g48090
GO:0008150 biological_process P
ND
AthAt4g17140
At1g47400
GO:0030437 ascospore formation P
IMP
SceS000003963
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000003963
ISS
SpoSPBC16C6.02c
SPBC21C3.01c
GO:0045184 establishment of protein localization P
RCA
SceS000003963
GO:0045324 late endosome to vacuole transport P
IGI
SceS000003963
IMP
SceS000003963
ISS
SpoSPBC21C3.01c
SPBC16C6.02c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
22068

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) VPS13A GI:66346674
Pan troglodytes (Ptr) VPS13A GI:114625095
Canis familiaris (Cfa) VPS13A GI:73946751
Mus musculus (Mmu) Vps13a
(MGI:2444304)
GI:66392160 A1ILH6
Rattus norvegicus (Rno) Vps13a GI:109459943
Drosophila melanogaster (Dme) CG2093
(FBgn0033194)
GI:161076367
Anopheles gambiae (Aga) AgaP_AGAP005082 GI:158292535
Caenorhabditis elegans (Cel) T08G11.1
(CE13443;
WBGene00011629)
GI:25143253
Saccharomyces cerevisiae (Sce) VPS13
(S000003963)
GI:6322988 Q07878
Kluyveromyces lactis (Kla) KLLA0E00638g GI:50307959
Eremothecium gossypii (Ego) AGOS_ACL064C GI:45185624
Magnaporthe grisea (Mgr) MGG_06537 GI:145608552
Neurospora crassa (Ncr) NCU05837.1 GI:32410423


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2444304
GO:0005622 intracellular C
NAS
HsaVPS13A
GO:0005739 mitochondrion C
IDA
SceS000003963
GO:0005768 endosome C
IDA
SceS000003963
GO:0019898 extrinsic to membrane C
IDA
SceS000003963
GO:0003674 molecular_function F
ND
MmuMGI:2444304
SceS000003963
GO:0005515 protein binding F
IPI
HsaVPS13A
GO:0006623 protein targeting to vacuole P
ISS
DmeFBgn0033194
GO:0006895 Golgi to endosome transport P
NAS
HsaVPS13A
GO:0007039 vacuolar protein catabolic process P
IMP
SceS000003963
RCA
SceS000003963
GO:0007399 nervous system development P
IMP
MmuMGI:2444304
GO:0007626 locomotory behavior P
IMP
MmuMGI:2444304
GO:0008104 protein localization P
NAS
HsaVPS13A
GO:0030437 ascospore formation P
IMP
SceS000003963
GO:0035176 social behavior P
IMP
MmuMGI:2444304
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000003963
GO:0045184 establishment of protein localization P
RCA
SceS000003963
GO:0045324 late endosome to vacuole transport P
IGI
SceS000003963
IMP
SceS000003963

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_346

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga462 ENSANGP00000003439
Anopheles gambiae (Aga) aga463 ENSANGP00000027991
Ashbya gossypii (Ago) ago985 ACL064C
Arabidopsis thaliana (Ath) ath4068 At1g48090.1
Arabidopsis thaliana (Ath) ath4069 At1g48090.2
Arabidopsis thaliana (Ath) ath24740 At5g24740.1
Caenorhabditis elegans (Cel) cel15027 T08G11.1a
(CE13443;
WBGene00011629)
Caenorhabditis elegans (Cel) cel15028 T08G11.1b
(CE30353)
Candida glabrata (Cgl) cgl555 CAGL0C03201g
Cryptococcus neoformans (Cne) cne5358 179.m00210
Dictyostelium discoideum (Ddi) ddi7874 DDB0187116
Dictyostelium discoideum (Ddi) ddi3879 DDB0217546
Debaryomyces hansenii (Dha) dha2908 DEHA0D13662g
Drosophila melanogaster (Dme) dme3684 CG2093-PA
(FBgn0033194)
Danio rerio (Dre) dre4492 ENSDARP00000002716
(chac)
Q8AYC0
Danio rerio (Dre) dre4490 ENSDARP00000008960
Danio rerio (Dre) dre23084 ENSDARP00000023634
Danio rerio (Dre) dre23083 ENSDARP00000027043
Danio rerio (Dre) dre4491 ENSDARP00000027680
Encephalitozoon cuniculi (Ecu) ecu784 19074146
Takifugu rubripes (Fru) fru1237 SINFRUP00000134324
Takifugu rubripes (Fru) fru1239 SINFRUP00000134326
Takifugu rubripes (Fru) fru1236 SINFRUP00000134332
Takifugu rubripes (Fru) fru5372 SINFRUP00000154590
Takifugu rubripes (Fru) fru5371 SINFRUP00000154593
Gallus gallus (Gga) gga24993 ENSGALP00000003085
Gallus gallus (Gga) gga3763 ENSGALP00000005861
(VPS13C)
Gallus gallus (Gga) gga3764 ENSGALP00000005863
Gallus gallus (Gga) gga3765 ENSGALP00000005864
Gallus gallus (Gga) gga27838 ENSGALP00000024437
Homo sapiens (Hsa) hsa10733 ENSP00000249837
(VPS13C)
Q709C8-3
Homo sapiens (Hsa) hsa10734 ENSP00000261517
(VPS13C)
Q709C8-1
Homo sapiens (Hsa) hsa31433 ENSP00000348011
(VPS13A)
Homo sapiens (Hsa) hsa31435 ENSP00000349985
(VPS13A)
Q96RL7-2
Homo sapiens (Hsa) hsa31434 ENSP00000350473
Homo sapiens (Hsa) hsa31432 ENSP00000353422
(VPS13A)
Q96RL7-1
Kluyveromyces lactis (Kla) kla2977 KLLA0E00638g
Mus musculus (Mmu) mmu27870 ENSMUSP00000036216
Mus musculus (Mmu) mmu13474 ENSMUSP00000041020
Mus musculus (Mmu) mmu13475 ENSMUSP00000044298
Mus musculus (Mmu) mmu27868 ENSMUSP00000054132
(MGI:2444207)
A1ILG9
Mus musculus (Mmu) mmu13473 ENSMUSP00000068716
(MGI:2444304)
Q5H8C4-1
Mus musculus (Mmu) mmu27871 ENSMUSP00000077040
(MGI:2444207)
Q8BX70-1
Neurospora crassa (Ncr) ncr5675 NCU05837.2
Oryza sativa (Osa) osa19851 3508.m00238
Oryza sativa (Osa) osa24330 3859.m00185
Oryza sativa (Osa) osa24336 3859.m00187
Oryza sativa (Osa) osa28719 4255.m00067
Oryza sativa (Osa) osa28724 4255.m00069
Rattus norvegicus (Rno) rno28859 ENSRNOP00000012501
(RGD:1560364)
Rattus norvegicus (Rno) rno3853 ENSRNOP00000014800
(RGD:1311340)
Rattus norvegicus (Rno) rno3854 ENSRNOP00000015108
(RGD:1311340)
Q7TP07
Rattus norvegicus (Rno) rno3856 ENSRNOP00000015838
Rattus norvegicus (Rno) rno28860 ENSRNOP00000030581
(RGD:1560364)
Saccharomyces cerevisiae (Sce) sce4050 YLL040C
(S000003963)
Schizosaccharomyces pombe (Spo) spo2525 SPBC16C6.02c O42926
Schizosaccharomyces pombe (Spo) spo1122 SPBC21C3.01c P87319
Yarrowia lipolytica (Yli) yli5632 YALI0F06791g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2444304
MGI:2444207
GO:0005739 mitochondrion C
IDA
SceS000003963
GO:0005768 endosome C
IDA
SceS000003963
ISS
SpoSPBC21C3.01c
SPBC16C6.02c
GO:0005829 cytosol C
IDA
SpoSPBC21C3.01c
GO:0009507 chloroplast C
IDA
AthAt1g48090
GO:0019898 extrinsic to membrane C
IDA
SceS000003963
GO:0003674 molecular_function F
ND
MmuMGI:2444304
MGI:2444207
SceS000003963
SpoSPBC16C6.02c
SPBC21C3.01c
GO:0035091 phosphoinositide binding F
ISS
AthAt1g48090
GO:0006623 protein targeting to vacuole P
ISS
DmeFBgn0033194
GO:0006886 intracellular protein transport P
IC
SpoSPBC16C6.02c
SPBC21C3.01c
GO:0007039 vacuolar protein catabolic process P
IMP
SceS000003963
RCA
SceS000003963
GO:0007165 signal transduction P
ISS
AthAt1g48090
GO:0007399 nervous system development P
IMP
MmuMGI:2444304
GO:0007626 locomotory behavior P
IMP
MmuMGI:2444304
GO:0008150 biological_process P
ND
MmuMGI:2444207
GO:0030437 ascospore formation P
IMP
SceS000003963
GO:0035176 social behavior P
IMP
MmuMGI:2444304
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000003963
ISS
SpoSPBC16C6.02c
SPBC21C3.01c
GO:0045184 establishment of protein localization P
RCA
SceS000003963
GO:0045324 late endosome to vacuole transport P
IGI
SceS000003963
IMP
SceS000003963
ISS
SpoSPBC21C3.01c
SPBC16C6.02c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC21C3.01c
(P87319)
YLL040C
(S000003963)
SPBC16C6.02c
(O42926)
YLL040C
(S000003963)