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Search term: YLR005W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SSL1
SGD link S000003995
Alternative ID YLR005W
Description Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kinase and DNA-dependent ATPase/helicase activities and is essential for transcription and nucleotide excision repair; interacts with Tfb4p
Synonyms YLR005W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2807 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g05050 GI:15220407
Caenorhabditis elegans (Cel) CE29053
(WBGene00011814)		 GI:17555086 P34567
Drosophila melanogaster (Dme) 7296597 GI:7296597
Homo sapiens (Hsa) Hs6681762
(GTF2H2)		 GI:6681762 Q13888
Saccharomyces cerevisiae (Sce) YLR005w
(S000003995)		 GI:6323033 Q04673
Schizosaccharomyces pombe (Spo) SPCC1682.07 GI:19075300 O74995
Encephalitozoon cuniculi (Ecu) ECU04g0280 GI:19074105 Q8SVX5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000112 nucleotide-excision repair factor 3
complex		 C
IDA
SceS000003995
GO:0000439 core TFIIH complex C
IDA
SceS000003995
GO:0005634 nucleus C
IDA
SpoSPCC1682.07
GO:0005654 nucleoplasm C
EXP
HsaGTF2H2
GO:0005675 holo TFIIH complex C
IDA
HsaGTF2H2
SceS000003995
TAS
SpoSPCC1682.07
GO:0005829 cytosol C
IDA
SpoSPCC1682.07
GO:0003676 nucleic acid binding F
TAS
HsaGTF2H2
GO:0003700 transcription factor activity F
NAS
HsaGTF2H2
GO:0004672 protein kinase activity F
IDA
HsaGTF2H2
GO:0005515 protein binding F
IPI
HsaGTF2H2
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaGTF2H2
GO:0008135 translation factor activity, nucleic acid
binding		 F
TAS
HsaGTF2H2
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity		 F
IDA
HsaGTF2H2
GO:0016251 general RNA polymerase II transcription factor
activity		 F
IDA
SceS000003995
ISS
SpoSPCC1682.07
GO:0047485 protein N-terminus binding F
IPI
HsaGTF2H2
GO:0000718 nucleotide-excision repair, DNA damage
removal		 P
EXP
HsaGTF2H2
GO:0002031 G-protein coupled receptor internalization P
IMP
HsaGTF2H2
GO:0002119 nematode larval development P
IMP
CelWBGene00011814
GO:0006281 DNA repair P
ISS
SpoSPCC1682.07
GO:0006289 nucleotide-excision repair P
IMP
SceS000003995
GO:0006366 transcription from RNA polymerase II
promoter		 P
IDA
HsaGTF2H2
GO:0006367 transcription initiation from RNA polymerase II
promoter		 P
EXP
HsaGTF2H2
IC
SpoSPCC1682.07
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
EXP
HsaGTF2H2
GO:0009411 response to UV P
TAS
HsaGTF2H2
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011814
GO:0010171 body morphogenesis P
IMP
CelWBGene00011814
GO:0032568 general transcription from RNA polymerase II
promoter		 P
IDA
SceS000003995
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011814
GO:0040011 locomotion P
IMP
CelWBGene00011814
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IDA
SceS000003995

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1159

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GTF2H2 GI:6681762 Q13888
Pan troglodytes (Ptr) GTF2H2 GI:114599827
Canis familiaris (Cfa) GTF2H2 GI:73949709
Mus musculus (Mmu) Gtf2h2
(MGI:1345669)		 GI:31981225 Q7TPV0
Rattus norvegicus (Rno) Gtf2h2 GI:34853502
Drosophila melanogaster (Dme) Ssl1
(FBgn0037202)		 GI:21356299
Anopheles gambiae (Aga) AgaP_AGAP010559 GI:158293200
Caenorhabditis elegans (Cel) T16H12.4
(CE29053;
WBGene00011814)		 GI:17555086 P34567
Schizosaccharomyces pombe (Spo) ssl1
(SPCC1682.07)		 GI:19075300 O74995
Saccharomyces cerevisiae (Sce) SSL1
(S000003995)		 GI:6323033 Q04673
Kluyveromyces lactis (Kla) KLLA0E09592g GI:50308759
Eremothecium gossypii (Ego) AGOS_ADR338C GI:45188211
Magnaporthe grisea (Mgr) MGG_06690 GI:39977611
Neurospora crassa (Ncr) NCU01831.1 GI:32415583
Arabidopsis thaliana (Ath) GTF2H2 GI:30679101
Oryza sativa (Osa) Os04g0508900 GI:115459348
Plasmodium falciparum (Pfa) MAL13P1.76 GI:124513058


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000112 nucleotide-excision repair factor 3
complex		 C
IDA
SceS000003995
GO:0000439 core TFIIH complex C
IDA
SceS000003995
GO:0005634 nucleus C
IDA
SpoSPCC1682.07
GO:0005654 nucleoplasm C
EXP
HsaGTF2H2
GO:0005675 holo TFIIH complex C
IDA
HsaGTF2H2
SceS000003995
ISS
DmeFBgn0037202
TAS
SpoSPCC1682.07
GO:0005829 cytosol C
IDA
SpoSPCC1682.07
GO:0020011 apicoplast C
RCA
PfaMAL13P1.76
GO:0003676 nucleic acid binding F
TAS
HsaGTF2H2
GO:0003700 transcription factor activity F
NAS
HsaGTF2H2
GO:0004672 protein kinase activity F
IDA
HsaGTF2H2
GO:0005515 protein binding F
IPI
HsaGTF2H2
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaGTF2H2
GO:0008135 translation factor activity, nucleic acid
binding		 F
TAS
HsaGTF2H2
GO:0008353 RNA polymerase II carboxy-terminal domain kinase
activity		 F
IDA
HsaGTF2H2
GO:0016251 general RNA polymerase II transcription factor
activity		 F
IDA
SceS000003995
ISS
DmeFBgn0037202
SpoSPCC1682.07
GO:0047485 protein N-terminus binding F
IPI
HsaGTF2H2
GO:0000718 nucleotide-excision repair, DNA damage
removal		 P
EXP
HsaGTF2H2
GO:0002031 G-protein coupled receptor internalization P
IMP
HsaGTF2H2
GO:0002119 nematode larval development P
IMP
CelWBGene00011814
GO:0006281 DNA repair P
ISS
SpoSPCC1682.07
GO:0006289 nucleotide-excision repair P
IMP
SceS000003995
GO:0006366 transcription from RNA polymerase II
promoter		 P
IDA
HsaGTF2H2
GO:0006367 transcription initiation from RNA polymerase II
promoter		 P
EXP
HsaGTF2H2
IC
SpoSPCC1682.07
ISS
DmeFBgn0037202
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
EXP
HsaGTF2H2
GO:0009411 response to UV P
TAS
HsaGTF2H2
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011814
GO:0010171 body morphogenesis P
IMP
CelWBGene00011814
GO:0032568 general transcription from RNA polymerase II
promoter		 P
IDA
SceS000003995
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011814
GO:0040011 locomotion P
IMP
CelWBGene00011814
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IDA
SceS000003995

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1906

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7524 ENSANGP00000016260
Ashbya gossypii (Ago) ago2079 ADR338C
Arabidopsis thaliana (Ath) ath456 At1g05055.1
Caenorhabditis elegans (Cel) cel15600 T16H12.4
(CE29053;
WBGene00011814)
Candida glabrata (Cgl) cgl1800 CAGL0G04059g
Cryptococcus neoformans (Cne) cne241 162.m02717
Cryptococcus neoformans (Cne) cne242 162.m04095
Dictyostelium discoideum (Ddi) ddi11794 DDB0231032
Debaryomyces hansenii (Dha) dha89 DEHA0A02035g
Drosophila melanogaster (Dme) dme10775 CG11115-PA
(FBgn0037202)
Danio rerio (Dre) dre19105 ENSDARP00000018901
(gtf2h2)		 Q7ZVV4
Encephalitozoon cuniculi (Ecu) ecu743 19074105
Takifugu rubripes (Fru) fru28514 SINFRUP00000155177
Gallus gallus (Gga) gga28184 ENSGALP00000003770
Homo sapiens (Hsa) hsa25358 ENSP00000274400
(GTF2H2)		 Q13888
Homo sapiens (Hsa) hsa25339 ENSP00000328901
(GTF2H2)		 Q13888
Kluyveromyces lactis (Kla) kla3383 KLLA0E09592g
Mus musculus (Mmu) mmu7463 ENSMUSP00000022141
Mus musculus (Mmu) mmu7464 ENSMUSP00000065228
(MGI:1345669)		 Q91YN8
Neurospora crassa (Ncr) ncr1783 NCU01831.2
Oryza sativa (Osa) osa82760 8195.m00163
Plasmodium falciparum (Pfa) pfa4306 MAL13P1.76
Rattus norvegicus (Rno) rno15432 ENSRNOP00000024615
Saccharomyces cerevisiae (Sce) sce4085 YLR005W
(S000003995)
Schizosaccharomyces pombe (Spo) spo2163 SPCC1682.07 O74995
Yarrowia lipolytica (Yli) yli3838 YALI0D26862g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000112 nucleotide-excision repair factor 3
complex		 C
IDA
SceS000003995
GO:0000439 core TFIIH complex C
IDA
SceS000003995
GO:0005634 nucleus C
IDA
SpoSPCC1682.07
GO:0005675 holo TFIIH complex C
IDA
SceS000003995
IGI
AthAt1g05055
ISS
DmeFBgn0037202
TAS
SpoSPCC1682.07
GO:0005829 cytosol C
IDA
SpoSPCC1682.07
GO:0020011 apicoplast C
RCA
PfaMAL13P1.76
GO:0016251 general RNA polymerase II transcription factor
activity		 F
IDA
SceS000003995
IGI
AthAt1g05055
ISS
DmeFBgn0037202
SpoSPCC1682.07
GO:0002119 nematode larval development P
IMP
CelWBGene00011814
GO:0006281 DNA repair P
ISS
SpoSPCC1682.07
GO:0006289 nucleotide-excision repair P
IGI
AthAt1g05055
IMP
SceS000003995
GO:0006358 regulation of transcription from RNA polymerase II
promoter, global		 P
IGI
AthAt1g05055
GO:0006367 transcription initiation from RNA polymerase II
promoter		 P
IC
SpoSPCC1682.07
ISS
DmeFBgn0037202
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00011814
GO:0010171 body morphogenesis P
IMP
CelWBGene00011814
GO:0032568 general transcription from RNA polymerase II
promoter		 P
IDA
SceS000003995
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011814
GO:0040011 locomotion P
IMP
CelWBGene00011814
GO:0070816 phosphorylation of RNA polymerase II C-terminal
domain		 P
IDA
SceS000003995

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1682.07
(O74995)		 YLR005W
(S000003995)