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Search term: YLR008C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PAM18
SGD link S000003998
Alternative ID YLR008C
Description Constituent of the import motor (PAM complex) component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); essential J-protein cochaperone that stimulates Ssc1p ATPase activity to drive import; inhibited by Pam16p
Synonyms YLR008C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0723 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Molecular chaperone (DnaJ superfamily)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g35795 GI:15227499
Arabidopsis thaliana (Ath) At3g09700 GI:18398610
Arabidopsis thaliana (Ath) At5g03030 GI:15242611
Caenorhabditis elegans (Cel) CE13742
(WBGene00001039)
GI:17509089 P91454
Drosophila melanogaster (Dme) 7294713 GI:7294713
Homo sapiens (Hsa) Hs7019453 GI:7019453
Homo sapiens (Hsa) Hs21687102 GI:18553709
Homo sapiens (Hsa) Hs18597269 GI:18597269
Saccharomyces cerevisiae (Sce) YLR008c
(S000003998)
GI:6323036 Q07914
Saccharomyces cerevisiae (Sce) YNL328c
(S000005272)
GI:6324001 P42834
Schizosaccharomyces pombe (Spo) SPAC824.06 GI:19114357 Q9UT37
Encephalitozoon cuniculi (Ecu) ECU11g0700 GI:19074870 Q8SU56
Arabidopsis thaliana (Ath) At2g35795 GI:15227499
Arabidopsis thaliana (Ath) At3g09700 GI:18398610
Arabidopsis thaliana (Ath) At5g03030 GI:15242611
Caenorhabditis elegans (Cel) CE13742
(WBGene00001039)
GI:17509089 P91454
Drosophila melanogaster (Dme) 7294713 GI:7294713
Homo sapiens (Hsa) Hs7019453 GI:7019453
Homo sapiens (Hsa) Hs21687102 GI:18553709
Homo sapiens (Hsa) Hs18597269 GI:18597269
Saccharomyces cerevisiae (Sce) YLR008c
(S000003998)
GI:6323036 Q07914
Saccharomyces cerevisiae (Sce) YNL328c
(S000005272)
GI:6324001 P42834
Schizosaccharomyces pombe (Spo) SPAC824.06 GI:19114357 Q9UT37
Encephalitozoon cuniculi (Ecu) ECU11g0700 GI:19074870 Q8SU56


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001405 presequence translocase-associated import
motor
C
IDA
SceS000003998
IPI
SceS000005272
ISS
SpoSPAC824.06
GO:0005575 cellular_component C
ND
AthAt2g35795
GO:0005739 mitochondrion C
IDA
SceS000003998
SpoSPAC824.06
GO:0005743 mitochondrial inner membrane C
IDA
SceS000005272
GO:0005744 mitochondrial inner membrane presequence
translocase complex
C
IDA
SceS000003998
GO:0001671 ATPase activator activity F
IDA
SceS000005272
IMP
SceS000003998
ISS
SpoSPAC824.06
GO:0008565 protein transporter activity F
IGI
SceS000005272
IPI
SceS000005272
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity
F
ISS
SpoSPAC824.06
GO:0030544 Hsp70 protein binding F
ISS
SpoSPAC824.06
GO:0051082 unfolded protein binding F
ISS
SceS000003998
SpoSPAC824.06
GO:0000003 reproduction P
IMP
CelWBGene00001039
GO:0002119 nematode larval development P
IMP
CelWBGene00001039
GO:0006457 protein folding P
ISS
AthAt3g09700
At2g35795
At5g03030
NAS
SpoSPAC824.06
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00001039
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00001039
GO:0030150 protein import into mitochondrial
matrix
P
IGI
SceS000005272
IMP
SceS000003998
IPI
SceS000005272
ISS
SpoSPAC824.06
GO:0040007 growth P
IMP
CelWBGene00001039

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
87176

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DNAJC19 GI:21687102
Pan troglodytes (Ptr) DNAJC19 GI:55621546
Canis familiaris (Cfa) DNAJC19 GI:74003214
Mus musculus (Mmu) Dnajc19
(MGI:1914963)
GI:71061477 Q9CQV7
Gallus gallus (Gga) DNAJC19 GI:50752403
Gallus gallus (Gga) DNAJC19 GI:118116070
Drosophila melanogaster (Dme) CG7394
(FBgn0036173)
GI:24662741
Anopheles gambiae (Aga) AgaP_AGAP003533 GI:158291735
Caenorhabditis elegans (Cel) dnj-21
(CE13742;
WBGene00001039)
GI:17509089 P91454
Schizosaccharomyces pombe (Spo) tim14
(SPAC824.06)
GI:19114357 Q9UT37
Saccharomyces cerevisiae (Sce) PAM18
(S000003998)
GI:6323036 Q07914
Kluyveromyces lactis (Kla) KLLA0E09438g GI:50308745
Eremothecium gossypii (Ego) AGOS_ADR345C GI:45188218
Magnaporthe grisea (Mgr) MGG_10159 GI:39969097
Neurospora crassa (Ncr) NCU00075.1 GI:32403096
Arabidopsis thaliana (Ath) AT3G09700 GI:18398610
Arabidopsis thaliana (Ath) AT5G03030 GI:15242611
Arabidopsis thaliana (Ath) AT2G35795 GI:18403957
Oryza sativa (Osa) Os07g0192300 GI:115471001
Oryza sativa (Osa) Os01g0157800 GI:115434628


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001405 presequence translocase-associated import
motor
C
IDA
SceS000003998
ISS
SpoSPAC824.06
GO:0005575 cellular_component C
ND
AthAt2g35795
GO:0005739 mitochondrion C
IDA
HsaDNAJC19
MmuMGI:1914963
SceS000003998
SpoSPAC824.06
GO:0005744 mitochondrial inner membrane presequence
translocase complex
C
IDA
SceS000003998
GO:0016021 integral to membrane C
NAS
HsaDNAJC19
GO:0001671 ATPase activator activity F
IMP
SceS000003998
ISS
SpoSPAC824.06
GO:0003674 molecular_function F
ND
MmuMGI:1914963
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity
F
ISS
SpoSPAC824.06
GO:0030544 Hsp70 protein binding F
ISS
SpoSPAC824.06
GO:0051082 unfolded protein binding F
ISS
SceS000003998
SpoSPAC824.06
GO:0000003 reproduction P
IMP
CelWBGene00001039
GO:0002119 nematode larval development P
IMP
CelWBGene00001039
GO:0006457 protein folding P
ISS
AthAt3g09700
At2g35795
At5g03030
NAS
HsaDNAJC19
SpoSPAC824.06
GO:0006626 protein targeting to mitochondrion P
NAS
HsaDNAJC19
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00001039
GO:0007601 visual perception P
IMP
HsaDNAJC19
GO:0008150 biological_process P
ND
MmuMGI:1914963
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00001039
GO:0030150 protein import into mitochondrial
matrix
P
IMP
SceS000003998
ISS
SpoSPAC824.06
GO:0040007 growth P
IMP
CelWBGene00001039
GO:0048806 genitalia development P
IMP
HsaDNAJC19

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1519

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga5966 ENSANGP00000011025
Ashbya gossypii (Ago) ago2086 ADR345C
Arabidopsis thaliana (Ath) ath10642 At2g35795.1
Arabidopsis thaliana (Ath) ath13049 At3g09700.1
Arabidopsis thaliana (Ath) ath22455 At5g03030.1
Caenorhabditis elegans (Cel) cel15686 T19B4.4
(CE13742;
WBGene00001039)
Candida glabrata (Cgl) cgl3034 CAGL0J00935g
Cryptococcus neoformans (Cne) cne2007 181.m07988
Dictyostelium discoideum (Ddi) ddi4874 DDB0185657
Debaryomyces hansenii (Dha) dha6723 DEHA0G22946g
Drosophila melanogaster (Dme) dme9074 CG7394-PA
(FBgn0036173)
Danio rerio (Dre) dre6045 ENSDARP00000042271
Encephalitozoon cuniculi (Ecu) ecu958 19074870
Takifugu rubripes (Fru) fru1408 SINFRUP00000161414
Gallus gallus (Gga) gga23635 ENSGALP00000014367
(DNAJC19)
Gallus gallus (Gga) gga2927 ENSGALP00000027365
(DNAJC15)
Homo sapiens (Hsa) hsa8735 ENSP00000261490
Kluyveromyces lactis (Kla) kla3376 KLLA0E09438g
Mus musculus (Mmu) mmu8535 ENSMUSP00000022590
(MGI:1913398)
Q78YY6
Mus musculus (Mmu) mmu24678 ENSMUSP00000079403
Neurospora crassa (Ncr) ncr73 NCU00075.2
Oryza sativa (Osa) osa7751 2558.m00213
Oryza sativa (Osa) osa9726 2737.m00106
Oryza sativa (Osa) osa20494 3433.m00097
Oryza sativa (Osa) osa37031 4854.m00152
Plasmodium falciparum (Pfa) pfa2433 PF07_0103
Rattus norvegicus (Rno) rno11734 ENSRNOP00000012530
(RGD:1307154)
Saccharomyces cerevisiae (Sce) sce4088 YLR008C
(S000003998)
Schizosaccharomyces pombe (Spo) spo3432 SPAC824.06 Q9UT37
Yarrowia lipolytica (Yli) yli1275 YALI0B12958g
Yarrowia lipolytica (Yli) yli2468 YALI0C18733g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001405 presequence translocase-associated import
motor
C
IDA
SceS000003998
ISS
SpoSPAC824.06
GO:0005575 cellular_component C
ND
AthAt2g35795
GO:0005739 mitochondrion C
IDA
MmuMGI:1913398
SceS000003998
SpoSPAC824.06
GO:0005744 mitochondrial inner membrane presequence
translocase complex
C
IDA
SceS000003998
GO:0020011 apicoplast C
RCA
PfaPF07_0103
GO:0001671 ATPase activator activity F
IMP
SceS000003998
ISS
SpoSPAC824.06
GO:0003674 molecular_function F
ND
MmuMGI:1913398
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity
F
ISS
SpoSPAC824.06
GO:0030544 Hsp70 protein binding F
ISS
SpoSPAC824.06
GO:0051082 unfolded protein binding F
ISS
PfaPF07_0103
SceS000003998
SpoSPAC824.06
GO:0000003 reproduction P
IMP
CelWBGene00001039
GO:0002119 nematode larval development P
IMP
CelWBGene00001039
GO:0006457 protein folding P
ISS
AthAt3g09700
At2g35795
At5g03030
NAS
SpoSPAC824.06
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00001039
GO:0008150 biological_process P
ND
MmuMGI:1913398
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00001039
GO:0030150 protein import into mitochondrial
matrix
P
IMP
SceS000003998
ISS
SpoSPAC824.06
GO:0040007 growth P
IMP
CelWBGene00001039

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC824.06
(Q9UT37)
YLR008C
(S000003998)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001405 presequence translocase-associated import
motor
C
IDA
SceS000003998
ISS
SpoSPAC824.06
GO:0005739 mitochondrion C
IDA
SceS000003998
SpoSPAC824.06
GO:0005744 mitochondrial inner membrane presequence
translocase complex
C
IDA
SceS000003998
GO:0001671 ATPase activator activity F
IMP
SceS000003998
ISS
SpoSPAC824.06
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity
F
ISS
SpoSPAC824.06
GO:0030544 Hsp70 protein binding F
ISS
SpoSPAC824.06
GO:0051082 unfolded protein binding F
ISS
SceS000003998
SpoSPAC824.06
GO:0006457 protein folding P
NAS
SpoSPAC824.06
GO:0030150 protein import into mitochondrial
matrix
P
IMP
SceS000003998
ISS
SpoSPAC824.06

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk