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Search term: YLR017W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MEU1
SGD link S000004007
Alternative ID YLR017W
Description Methylthioadenosine phosphorylase (MTAP), catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression
Synonyms YLR017W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3985 -CDHYP-

KOGs classification KOGs description
METABOLISM Methylthioadenosine phosphorylase MTAP

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE01747 GI:17531237
Drosophila melanogaster (Dme) 7302794
(FBgn0034215)		 GI:20130079
Homo sapiens (Hsa) Hs4505273 GI:4505273
Saccharomyces cerevisiae (Sce) YLR017w
(S000004007)		 GI:6323045 Q07938
Schizosaccharomyces pombe (Spo) SPAC16C9.02c GI:19113988 Q09816


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DmeFBgn0034215
GO:0005634 nucleus C
IDA
SpoSPAC16C9.02c
GO:0005737 cytoplasm C
IDA
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0005829 cytosol C
IDA
SpoSPAC16C9.02c
GO:0017061 S-methyl-5-thioadenosine phosphorylase
activity		 F
IDA
SceS000004007
IMP
SceS000004007
ISS
DmeFBgn0034215
SpoSPAC16C9.02c
NAS
DmeFBgn0034215
GO:0006537 glutamate biosynthetic process P
IMP
SceS000004007
GO:0016310 phosphorylation P
NAS
DmeFBgn0034215
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004007
GO:0019509 L-methionine salvage from methylthioadenosine P
IDA
SceS000004007
IMP
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004007

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1838

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MTAP GI:47132622
Pan troglodytes (Ptr) MTAP GI:114623942
Canis familiaris (Cfa) MTAP GI:73971706
Mus musculus (Mmu) Mtap
(MGI:1914152)		 GI:45544618 Q9CQ65
Gallus gallus (Gga) MTAP GI:71896239
Drosophila melanogaster (Dme) CG4802
(FBgn0034215)		 GI:20130079
Anopheles gambiae (Aga) AgaP_AGAP005129 GI:158292620
Caenorhabditis elegans (Cel) B0228.7
(CE34630;
WBGene00015064)		 GI:71980569
Schizosaccharomyces pombe (Spo) SPAC16C9.02c GI:19113988 Q09816
Saccharomyces cerevisiae (Sce) MEU1
(S000004007)		 GI:6323045 Q07938
Kluyveromyces lactis (Kla) KLLA0F15664g GI:50311519
Magnaporthe grisea (Mgr) MGG_06498 GI:39977191
Neurospora crassa (Ncr) NCU03963.1 GI:32405338


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DmeFBgn0034215
GO:0005634 nucleus C
IDA
SpoSPAC16C9.02c
GO:0005737 cytoplasm C
IDA
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0005829 cytosol C
IDA
SpoSPAC16C9.02c
GO:0004645 phosphorylase activity F
TAS
HsaMTAP
GO:0017061 S-methyl-5-thioadenosine phosphorylase
activity		 F
IDA
SceS000004007
IMP
SceS000004007
ISS
DmeFBgn0034215
SpoSPAC16C9.02c
NAS
DmeFBgn0034215
GO:0006139 nucleobase, nucleoside, nucleotide and nucleic
acid metabolic process		 P
TAS
HsaMTAP
GO:0006537 glutamate biosynthetic process P
IMP
SceS000004007
GO:0016310 phosphorylation P
NAS
DmeFBgn0034215
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004007
GO:0019509 L-methionine salvage from methylthioadenosine P
IDA
SceS000004007
IMP
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004007

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2329

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga509 ENSANGP00000010010
Ashbya gossypii (Ago) ago27 AAL160W
Caenorhabditis elegans (Cel) cel203 B0228.7
(CE34630;
WBGene00015064)
Candida glabrata (Cgl) cgl800 CAGL0D03190g
Cryptococcus neoformans (Cne) cne1955 181.m07930
Debaryomyces hansenii (Dha) dha2010 DEHA0C13145g
Drosophila melanogaster (Dme) dme14347 CG31115-PA
(FBgn0051115)
Drosophila melanogaster (Dme) dme5631 CG4802-PA
(FBgn0034215)
Danio rerio (Dre) dre31251 ENSDARP00000042093
Takifugu rubripes (Fru) fru21072 SINFRUP00000153460
Takifugu rubripes (Fru) fru21071 SINFRUP00000166050
Gallus gallus (Gga) gga24028 ENSGALP00000013273
(MTAP)		 Q5ZHQ7
Gallus gallus (Gga) gga24029 ENSGALP00000013274
Homo sapiens (Hsa) hsa31089 ENSP00000297736
Kluyveromyces lactis (Kla) kla4784 KLLA0F15664g
Mus musculus (Mmu) mmu18411 ENSMUSP00000061092
(MGI:1914152)		 Q9CQ65
Neurospora crassa (Ncr) ncr3850 NCU03963.2
Rattus norvegicus (Rno) rno23414 ENSRNOP00000008686
(RGD:1310114)
Rattus norvegicus (Rno) rno23413 ENSRNOP00000031214
(RGD:1310114)		 Q7TP15
Saccharomyces cerevisiae (Sce) sce4097 YLR017W
(S000004007)
Schizosaccharomyces pombe (Spo) spo4505 SPAC16C9.02c Q09816
Yarrowia lipolytica (Yli) yli1292 YALI0B13420g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DmeFBgn0034215
GO:0005634 nucleus C
IDA
SpoSPAC16C9.02c
GO:0005737 cytoplasm C
IDA
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0005829 cytosol C
IDA
SpoSPAC16C9.02c
GO:0017061 S-methyl-5-thioadenosine phosphorylase
activity		 F
IDA
SceS000004007
IMP
SceS000004007
ISS
DmeFBgn0034215
FBgn0051115
SpoSPAC16C9.02c
NAS
DmeFBgn0034215
GO:0006537 glutamate biosynthetic process P
IMP
SceS000004007
GO:0016310 phosphorylation P
NAS
DmeFBgn0034215
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004007
GO:0019509 L-methionine salvage from methylthioadenosine P
IDA
SceS000004007
IMP
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004007

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC16C9.02c
(Q09816)		 YLR017W
(S000004007)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC16C9.02c
GO:0005737 cytoplasm C
IDA
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0005829 cytosol C
IDA
SpoSPAC16C9.02c
GO:0017061 S-methyl-5-thioadenosine phosphorylase
activity		 F
IDA
SceS000004007
IMP
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0006537 glutamate biosynthetic process P
IMP
SceS000004007
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004007
GO:0019509 L-methionine salvage from methylthioadenosine P
IDA
SceS000004007
IMP
SceS000004007
ISS
SpoSPAC16C9.02c
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004007

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GO info in one table:

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