YOGY Home YOGY Help

Search term: YLR056W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERG3
SGD link S000004046
Alternative ID YLR056W
Description C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources
Synonyms YLR056W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0872 AC-HYP-

KOGs classification KOGs description
METABOLISM Sterol C5 desaturase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g02580 GI:15232935
Arabidopsis thaliana (Ath) At3g02590 GI:15232937
Caenorhabditis elegans (Cel) CE15565 GI:17551916
Homo sapiens (Hsa) Hs5902070 GI:5902070
Homo sapiens (Hsa) Hs20558831 GI:20558831
Saccharomyces cerevisiae (Sce) YLR056w
(S000004046)		 GI:6323085 P32353
Schizosaccharomyces pombe (Spo) SPAC1687.16c GI:19114047 O94457
Arabidopsis thaliana (Ath) At3g02580 GI:15232935
Arabidopsis thaliana (Ath) At3g02590 GI:15232937
Caenorhabditis elegans (Cel) CE15565 GI:17551916
Homo sapiens (Hsa) Hs5902070 GI:5902070
Homo sapiens (Hsa) Hs20558831 GI:20558831
Saccharomyces cerevisiae (Sce) YLR056w
(S000004046)		 GI:6323085 P32353
Schizosaccharomyces pombe (Spo) SPAC1687.16c GI:19114047 O94457


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000004046
SpoSPAC1687.16c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC1687.16c
GO:0030176 integral to endoplasmic reticulum
membrane		 C
ISS
SpoSPAC1687.16c
GO:0000248 C-5 sterol desaturase activity F
IDA
SceS000004046
IGI
AthAt3g02580
IMP
AthAt3g02580
ISS
AthAt3g02590
SpoSPAC1687.16c
GO:0005506 iron ion binding F
ISS
SpoSPAC1687.16c
GO:0006066 alcohol metabolic process P
RCA
SceS000004046
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPAC1687.16c
IMP
SceS000004046
GO:0016126 sterol biosynthetic process P
IMP
AthAt3g02580
ISS
AthAt3g02590
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004046
GO:0044255 cellular lipid metabolic process P
RCA
SceS000004046
GO:0071210 protein insertion into membrane
raft		 P
IMP
SpoSPAC1687.16c
GO:0090002 establishment of protein localization in plasma
membrane		 P
IMP
SpoSPAC1687.16c

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5044

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SC5DL GI:68160945
Pan troglodytes (Ptr) SC5DL GI:114640840
Canis familiaris (Cfa) SC5DL GI:73955000
Mus musculus (Mmu) Sc5d
(MGI:1353611)		 GI:27777693 O88822
Rattus norvegicus (Rno) Sc5dl GI:25742651
Schizosaccharomyces pombe (Spo) erg3 GI:19114047
Saccharomyces cerevisiae (Sce) ERG3
(S000004046)		 GI:6323085 P32353
Kluyveromyces lactis (Kla) KLLA0F08855g GI:50310919
Eremothecium gossypii (Ego) AGOS_AFR151C GI:45198669
Magnaporthe grisea (Mgr) MGG_08832 GI:39953467
Neurospora crassa (Ncr) NCU06207.1 GI:32411163
Arabidopsis thaliana (Ath) AT3G02590 GI:15232937
Arabidopsis thaliana (Ath) STE1 GI:15232935
Oryza sativa (Osa) Os01g0134500 GI:115434372


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
AthSTE1
SceS000004046
GO:0005792 microsome C
ISO
MmuMGI:1353611
GO:0000248 C-5 sterol desaturase activity F
IDA
SceS000004046
IGI
AthSTE1
IMP
AthSTE1
ISO
MmuMGI:1353611
ISS
AthAt3g02590
TAS
HsaSC5DL
GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl
O-methyltransferase activity		 F
IDA
AthSTE1
IGI
AthSTE1
ISS
AthSTE1
GO:0010340 carboxyl-O-methyltransferase activity F
IMP
AthSTE1
GO:0006066 alcohol metabolic process P
RCA
SceS000004046
GO:0006481 C-terminal protein amino acid methylation P
IDA
AthSTE1
IMP
AthSTE1
ISS
AthSTE1
GO:0006629 lipid metabolic process P
TAS
HsaSC5DL
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000004046
GO:0009788 negative regulation of abscisic acid mediated
signaling pathway		 P
NAS
AthSTE1
GO:0009908 flower development P
IMP
AthSTE1
GO:0016126 sterol biosynthetic process P
IMP
AthSTE1
ISS
AthAt3g02590
GO:0033490 cholesterol biosynthetic process via
lathosterol		 P
ISO
MmuMGI:1353611
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004046
GO:0044255 cellular lipid metabolic process P
RCA
SceS000004046
GO:0048367 shoot development P
IMP
AthSTE1

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4534

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3343 AFR151C
Arabidopsis thaliana (Ath) ath12277 At3g02580.1
Arabidopsis thaliana (Ath) ath12278 At3g02590.1
Candida glabrata (Cgl) cgl1308 CAGL0F01793g
Cryptococcus neoformans (Cne) cne2236 181.m08258
Cryptococcus neoformans (Cne) cne2237 181.m08622
Debaryomyces hansenii (Dha) dha4817 DEHA0F09757g
Takifugu rubripes (Fru) fru17031 SINFRUP00000150345
Homo sapiens (Hsa) hsa6705 ENSP00000264027
(SC5DL)		 O75845
Kluyveromyces lactis (Kla) kla4482 KLLA0F08855g
Mus musculus (Mmu) mmu27447 ENSMUSP00000034516
Mus musculus (Mmu) mmu27448 ENSMUSP00000057354
(MGI:1353611)		 Q8BGI0
Neurospora crassa (Ncr) ncr4839 NCU04983.2
Neurospora crassa (Ncr) ncr6032 NCU06207.2
Oryza sativa (Osa) osa12396 2840.m00174
Rattus norvegicus (Rno) rno28418 ENSRNOP00000011284
(RGD:620775)		 Q9EQS5
Saccharomyces cerevisiae (Sce) sce4137 YLR056W
(S000004046)
Schizosaccharomyces pombe (Spo) spo4185 SPAC1687.16c O94457
Schizosaccharomyces pombe (Spo) spo117 SPBC27B12.03c O13666
Yarrowia lipolytica (Yli) yli3578 YALI0D20878g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000004046
SpoSPAC1687.16c
SPBC27B12.03c
GO:0005789 endoplasmic reticulum membrane C
NAS
SpoSPBC27B12.03c
GO:0005792 microsome C
ISO
MmuMGI:1353611
GO:0005794 Golgi apparatus C
IDA
SpoSPAC1687.16c
SPBC27B12.03c
GO:0030176 integral to endoplasmic reticulum
membrane		 C
ISS
SpoSPAC1687.16c
GO:0000248 C-5 sterol desaturase activity F
IDA
SceS000004046
IGI
AthAt3g02580
IMP
AthAt3g02580
ISO
MmuMGI:1353611
ISS
AthAt3g02590
SpoSPAC1687.16c
SPBC27B12.03c
GO:0005506 iron ion binding F
ISS
SpoSPAC1687.16c
SPBC27B12.03c
GO:0006066 alcohol metabolic process P
RCA
SceS000004046
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPAC1687.16c
SPBC27B12.03c
IMP
SceS000004046
SpoSPBC27B12.03c
GO:0016126 sterol biosynthetic process P
IMP
AthAt3g02580
ISS
AthAt3g02590
GO:0033490 cholesterol biosynthetic process via
lathosterol		 P
ISO
MmuMGI:1353611
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004046
GO:0044255 cellular lipid metabolic process P
RCA
SceS000004046
GO:0071210 protein insertion into membrane
raft		 P
IMP
SpoSPAC1687.16c
SPBC27B12.03c
GO:0090002 establishment of protein localization in plasma
membrane		 P
IMP
SpoSPAC1687.16c
SPBC27B12.03c

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC27B12.03c
(O13666)		 YLR056W
(S000004046)
SPAC1687.16c
(O94457)		 YLR056W
(S000004046)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000004046
SpoSPAC1687.16c
SPBC27B12.03c
GO:0005789 endoplasmic reticulum membrane C
NAS
SpoSPBC27B12.03c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC1687.16c
SPBC27B12.03c
GO:0030176 integral to endoplasmic reticulum
membrane		 C
ISS
SpoSPAC1687.16c
GO:0000248 C-5 sterol desaturase activity F
IDA
SceS000004046
ISS
SpoSPAC1687.16c
SPBC27B12.03c
GO:0005506 iron ion binding F
ISS
SpoSPAC1687.16c
SPBC27B12.03c
GO:0006066 alcohol metabolic process P
RCA
SceS000004046
GO:0006696 ergosterol biosynthetic process P
IGI
SpoSPAC1687.16c
SPBC27B12.03c
IMP
SceS000004046
SpoSPBC27B12.03c
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004046
GO:0044255 cellular lipid metabolic process P
RCA
SceS000004046
GO:0071210 protein insertion into membrane
raft		 P
IMP
SpoSPAC1687.16c
SPBC27B12.03c
GO:0090002 establishment of protein localization in plasma
membrane		 P
IMP
SpoSPAC1687.16c
SPBC27B12.03c

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk