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Search term: YLR066W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SPC3
SGD link S000004056
Alternative ID YLR066W
Description Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23
Synonyms YLR066W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3372 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Signal peptidase complex subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g05230 GI:18397160
Arabidopsis thaliana (Ath) At5g27430 GI:15240934
Caenorhabditis elegans (Cel) CE00269
(WBGene00019679)		 GI:17554176 P34525
Drosophila melanogaster (Dme) 7301130 GI:17369766
Homo sapiens (Hsa) Hs11345462
(SPCS3)		 GI:11345462 P61009
Saccharomyces cerevisiae (Sce) YLR066w
(S000004056)		 GI:6323095 Q12133
Schizosaccharomyces pombe (Spo) SPAC56F8.11 GI:19114137 Q10259
Encephalitozoon cuniculi (Ecu) ECU09g0960 GI:19173218


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt3g05230
At5g27430
GO:0005783 endoplasmic reticulum C
IDA
AthAt3g05230
HsaSPCS3
SpoSPAC56F8.11
GO:0005787 signal peptidase complex C
IDA
SceS000004056
ISS
SpoSPAC56F8.11
GO:0008233 peptidase activity F
IMP
SceS000004056
GO:0000003 reproduction P
IMP
CelWBGene00019679
GO:0002119 nematode larval development P
IMP
CelWBGene00019679
GO:0006465 signal peptide processing P
IDA
SceS000004056
IGI
SceS000004056
IMP
SceS000004056
IPI
SceS000004056
ISS
AthAt5g27430
At3g05230
SceS000004056
SpoSPAC56F8.11
GO:0006518 peptide metabolic process P
RCA
SceS000004056
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00019679
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019679
GO:0016485 protein processing P
RCA
SceS000004056
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00019679
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019679
GO:0040011 locomotion P
IMP
CelWBGene00019679
GO:0045047 protein targeting to ER P
IMP
SceS000004056
ISS
SpoSPAC56F8.11
GO:0051604 protein maturation P
RCA
SceS000004056

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39669

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SPC3
(S000004056)		 GI:6323095 Q12133
Kluyveromyces lactis (Kla) KLLA0D05401g GI:50306655
Eremothecium gossypii (Ego) AGOS_ABR224W GI:45185456


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005787 signal peptidase complex C
IDA
SceS000004056
GO:0008233 peptidase activity F
IMP
SceS000004056
GO:0006465 signal peptide processing P
IDA
SceS000004056
IGI
SceS000004056
IMP
SceS000004056
IPI
SceS000004056
ISS
SceS000004056
GO:0006518 peptide metabolic process P
RCA
SceS000004056
GO:0016485 protein processing P
RCA
SceS000004056
GO:0045047 protein targeting to ER P
IMP
SceS000004056
GO:0051604 protein maturation P
RCA
SceS000004056

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1801

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8421 ENSANGP00000018480
Ashbya gossypii (Ago) ago818 ABR224W
Arabidopsis thaliana (Ath) ath12576 At3g05230.1
Arabidopsis thaliana (Ath) ath25016 At5g27430.1
Caenorhabditis elegans (Cel) cel12701 K12H4.4
(CE00269;
WBGene00019679)
Candida glabrata (Cgl) cgl1299 CAGL0F01595g
Cryptococcus neoformans (Cne) cne2793 183.m01733
Dictyostelium discoideum (Ddi) ddi8309 DDB0189116
Debaryomyces hansenii (Dha) dha3907 DEHA0E15026g
Drosophila melanogaster (Dme) dme14184 CG5677-PA
(FBgn0039172)
Danio rerio (Dre) dre4682 ENSDARP00000043294
Danio rerio (Dre) dre4681 ENSDARP00000050708
Takifugu rubripes (Fru) fru15885 SINFRUP00000149361
Gallus gallus (Gga) gga17585 ENSGALP00000017599
(SPCS3)
Homo sapiens (Hsa) hsa24880 ENSP00000264597
(SPCS3)		 P61009
Kluyveromyces lactis (Kla) kla2300 KLLA0D05401g
Mus musculus (Mmu) mmu29577 ENSMUSP00000051250
(MGI:1923469)		 Q9D365
Mus musculus (Mmu) mmu29578 ENSMUSP00000062660
(MGI:1923469)		 Q9D365
Mus musculus (Mmu) mmu25966 ENSMUSP00000070267
(MGI:1923937)		 Q6ZWQ7
Neurospora crassa (Ncr) ncr6493 NCU06677.2
Oryza sativa (Osa) osa10239 2747.m00128
Oryza sativa (Osa) osa59480 6523.m00194
Plasmodium falciparum (Pfa) pfa4510 PFI0215c
Rattus norvegicus (Rno) rno32028 ENSRNOP00000039058
(RGD:1563536)		 Q568Z4
Rattus norvegicus (Rno) rno32027 ENSRNOP00000045679
(RGD:1563536)		 Q568Z4
Saccharomyces cerevisiae (Sce) sce4147 YLR066W
(S000004056)
Schizosaccharomyces pombe (Spo) spo3349 SPAC56F8.11 Q10259
Yarrowia lipolytica (Yli) yli4869 YALI0E24321g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1923937
MGI:1923469
GO:0005618 cell wall C
IDA
AthAt3g05230
At5g27430
GO:0005783 endoplasmic reticulum C
IDA
AthAt3g05230
SpoSPAC56F8.11
GO:0005787 signal peptidase complex C
IDA
SceS000004056
ISS
DmeFBgn0039172
SpoSPAC56F8.11
NAS
DmeFBgn0039172
GO:0003674 molecular_function F
ND
MmuMGI:1923937
MGI:1923469
GO:0008233 peptidase activity F
IMP
SceS000004056
ISS
DmeFBgn0039172
NAS
DmeFBgn0039172
GO:0000003 reproduction P
IMP
CelWBGene00019679
GO:0002119 nematode larval development P
IMP
CelWBGene00019679
GO:0006465 signal peptide processing P
IDA
SceS000004056
IGI
SceS000004056
IMP
SceS000004056
IPI
SceS000004056
ISS
AthAt5g27430
At3g05230
DmeFBgn0039172
SceS000004056
SpoSPAC56F8.11
NAS
DmeFBgn0039172
GO:0006518 peptide metabolic process P
RCA
SceS000004056
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00019679
GO:0008150 biological_process P
ND
MmuMGI:1923937
MGI:1923469
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019679
GO:0016485 protein processing P
RCA
SceS000004056
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00019679
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019679
GO:0040011 locomotion P
IMP
CelWBGene00019679
GO:0045047 protein targeting to ER P
IMP
SceS000004056
ISS
SpoSPAC56F8.11
GO:0051604 protein maturation P
RCA
SceS000004056

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC56F8.11
(Q10259)		 YLR066W
(S000004056)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC56F8.11
GO:0005787 signal peptidase complex C
IDA
SceS000004056
ISS
SpoSPAC56F8.11
GO:0008233 peptidase activity F
IMP
SceS000004056
GO:0006465 signal peptide processing P
IDA
SceS000004056
IGI
SceS000004056
IMP
SceS000004056
IPI
SceS000004056
ISS
SceS000004056
SpoSPAC56F8.11
GO:0006518 peptide metabolic process P
RCA
SceS000004056
GO:0016485 protein processing P
RCA
SceS000004056
GO:0045047 protein targeting to ER P
IMP
SceS000004056
ISS
SpoSPAC56F8.11
GO:0051604 protein maturation P
RCA
SceS000004056

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