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Search term: YLR079W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SIC1
SGD link S000004069
Alternative ID YLR079W
Description Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1
Synonyms YLR079W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48889

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SIC1
(S000004069)
GI:6323108
Kluyveromyces lactis (Kla) KLLA0D05797g GI:50306693
Eremothecium gossypii (Ego) AGOS_ABR240W GI:45185472


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004069
GO:0005737 cytoplasm C
IDA
SceS000004069
GO:0004861 cyclin-dependent protein kinase inhibitor
activity
F
IDA
SceS000004069
IPI
SceS000004069
GO:0000079 regulation of cyclin-dependent protein kinase
activity
P
IDA
SceS000004069
IEP
SceS000004069
IMP
SceS000004069
IPI
SceS000004069
GO:0000082 G1/S transition of mitotic cell
cycle
P
IEP
SceS000004069
IGI
SceS000004069
GO:0016242 negative regulation of macroautophagy P
IMP
SceS000004069
GO:0050790 regulation of catalytic activity P
RCA
SceS000004069
GO:0051726 regulation of cell cycle P
RCA
SceS000004069

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_31388

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago834 ABR240W
Candida glabrata (Cgl) cgl4652 CAGL0L13222g
Kluyveromyces lactis (Kla) kla2319 KLLA0D05797g
Saccharomyces cerevisiae (Sce) sce4160 YLR079W
(S000004069)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004069
GO:0005737 cytoplasm C
IDA
SceS000004069
GO:0004861 cyclin-dependent protein kinase inhibitor
activity
F
IDA
SceS000004069
IPI
SceS000004069
GO:0000079 regulation of cyclin-dependent protein kinase
activity
P
IDA
SceS000004069
IEP
SceS000004069
IMP
SceS000004069
IPI
SceS000004069
GO:0000082 G1/S transition of mitotic cell
cycle
P
IEP
SceS000004069
IGI
SceS000004069
GO:0016242 negative regulation of macroautophagy P
IMP
SceS000004069
GO:0050790 regulation of catalytic activity P
RCA
SceS000004069
GO:0051726 regulation of cell cycle P
RCA
SceS000004069

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