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Search term: YLR099C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ICT1
SGD link S000004089
Alternative ID YLR099C
Description Lysophosphatidic acid acyltransferase, responsible for enhanced phospholipid synthesis during organic solvent stress; null displays increased sensitivity to Calcofluor white; highly expressed during organic solvent stress
Synonyms YLR099C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4409 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Predicted hydrolase/acyltransferase (alpha/beta hydrolase superfamily)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g24160 GI:15233712
Arabidopsis thaliana (Ath) At4g33190 GI:15234101
Caenorhabditis elegans (Cel) CE08378 GI:17505715
Caenorhabditis elegans (Cel) CE08626 GI:17558490
Caenorhabditis elegans (Cel) CE08627
(WBGene00016507)		 GI:17558492 P91141
Drosophila melanogaster (Dme) 7304150 GI:7304150
Homo sapiens (Hsa) Hs11545767 GI:11545767
Homo sapiens (Hsa) Hs7705771 GI:7705771
Saccharomyces cerevisiae (Sce) YDR125c
(S000002532)		 GI:6320330 Q04623
Saccharomyces cerevisiae (Sce) YGR110w
(S000003342)		 GI:6321548 P53264
Saccharomyces cerevisiae (Sce) YLR099c
(S000004089)		 GI:6323128 Q12385
Schizosaccharomyces pombe (Spo) SPAC6G10.03c GI:19115012 O14249


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004089
GO:0005737 cytoplasm C
IDA
SpoSPAC6G10.03c
GO:0005739 mitochondrion C
IDA
SceS000002532
S000003342
ISS
SpoSPAC6G10.03c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC6G10.03c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC6G10.03c
GO:0003674 molecular_function F
ND
SceS000002532
GO:0004623 phospholipase A2 activity F
IDA
AthAt4g24160
SceS000003342
IMP
SceS000003342
ISS
SpoSPAC6G10.03c
GO:0016298 lipase activity F
IDA
AthAt4g24160
GO:0016787 hydrolase activity F
ISS
AthAt4g24160
GO:0042171 lysophosphatidic acid acyltransferase
activity		 F
IDA
AthAt4g24160
SceS000004089
GO:0006654 phosphatidic acid biosynthetic
process		 P
IMP
SceS000004089
GO:0019915 lipid storage P
IMP
CelWBGene00016507
GO:0031505 fungal-type cell wall organization P
IMP
SceS000002532
GO:0032048 cardiolipin metabolic process P
IDA
SceS000003342
IGI
SceS000003342
ISS
SpoSPAC6G10.03c
GO:0033554 cellular response to stress P
IEP
SpoSPAC6G10.03c
GO:0040011 locomotion P
IMP
CelWBGene00016507

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74750

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) ICT1
(S000004089)		 GI:6323128 Q12385
Eremothecium gossypii (Ego) AGOS_AGR062C GI:45201157


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004089
GO:0042171 lysophosphatidic acid acyltransferase
activity		 F
IDA
SceS000004089
GO:0006654 phosphatidic acid biosynthetic
process		 P
IMP
SceS000004089

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_861

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10148 ENSANGP00000010452
Anopheles gambiae (Aga) aga15456 ENSANGP00000017492
Ashbya gossypii (Ago) ago573 ABL019W
Ashbya gossypii (Ago) ago4372 AGR062C
Arabidopsis thaliana (Ath) ath20372 At4g24160.1
Arabidopsis thaliana (Ath) ath20373 At4g24160.2
Caenorhabditis elegans (Cel) cel2620 C25A1.12
(CE41871;
WBGene00007711)
Caenorhabditis elegans (Cel) cel3662 C37H5.3a
(CE08627;
WBGene00016507)
Caenorhabditis elegans (Cel) cel3663 C37H5.3b
(CE32824)
Candida glabrata (Cgl) cgl4283 CAGL0L04686g
Candida glabrata (Cgl) cgl5153 CAGL0M11462g
Cryptococcus neoformans (Cne) cne2927 167.m03213
Debaryomyces hansenii (Dha) dha1275 DEHA0B13695g
Debaryomyces hansenii (Dha) dha5467 DEHA0F24211g
Debaryomyces hansenii (Dha) dha5954 DEHA0G05742g
Drosophila melanogaster (Dme) dme3737 CG1882-PA
(FBgn0033226)
Drosophila melanogaster (Dme) dme3740 CG1882-PB
(FBgn0033226)
Drosophila melanogaster (Dme) dme3738 CG1882-PC
(FBgn0033226)
Drosophila melanogaster (Dme) dme3739 CG1882-PD
(FBgn0033226)
Danio rerio (Dre) dre11814 ENSDARP00000003897
Danio rerio (Dre) dre11812 ENSDARP00000011009
Danio rerio (Dre) dre11813 ENSDARP00000028738
(zgc:110267)		 Q568J2
Takifugu rubripes (Fru) fru28512 SINFRUP00000139105
Takifugu rubripes (Fru) fru59 SINFRUP00000149708
Takifugu rubripes (Fru) fru29722 SINFRUP00000155355
Gallus gallus (Gga) gga10015 ENSGALP00000018741
(ABHD5)		 Q5ZKV3
Homo sapiens (Hsa) hsa22324 ENSP00000013894
(ABHD5)		 C9JBE4
Homo sapiens (Hsa) hsa9214 ENSP00000216327
(ABHD4)		 Q8TB40
Kluyveromyces lactis (Kla) kla1104 KLLA0B12914g
Mus musculus (Mmu) mmu28516 ENSMUSP00000035128
(MGI:1914719)		 Q9DBL9-1
Mus musculus (Mmu) mmu8151 ENSMUSP00000044134
(MGI:1915938)		 Q3U7M5
Neurospora crassa (Ncr) ncr6151 NCU06332.2
Oryza sativa (Osa) osa66099 6777.m00063
Rattus norvegicus (Rno) rno29426 ENSRNOP00000000239
(RGD:1303237)		 Q6QA69
Rattus norvegicus (Rno) rno11320 ENSRNOP00000012837
(RGD:1311858)
Saccharomyces cerevisiae (Sce) sce2480 YGR110W
(S000003342)
Saccharomyces cerevisiae (Sce) sce4180 YLR099C
(S000004089)
Schizosaccharomyces pombe (Spo) spo1517 SPAC6G10.03c O14249
Yarrowia lipolytica (Yli) yli2015 YALI0C07326g
Yarrowia lipolytica (Yli) yli3446 YALI0D17842g
Yarrowia lipolytica (Yli) yli5321 YALI0E34881g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004089
GO:0005737 cytoplasm C
IDA
SpoSPAC6G10.03c
GO:0005739 mitochondrion C
IDA
SceS000003342
ISS
SpoSPAC6G10.03c
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC6G10.03c
GO:0005794 Golgi apparatus C
IDA
SpoSPAC6G10.03c
GO:0005811 lipid particle C
EXP
MmuMGI:1914719
IDA
DmeFBgn0033226
MmuMGI:1914719
GO:0005829 cytosol C
EXP
MmuMGI:1914719
IDA
MmuMGI:1914719
GO:0004623 phospholipase A2 activity F
IDA
AthAt4g24160
SceS000003342
IMP
SceS000003342
ISS
SpoSPAC6G10.03c
GO:0005515 protein binding F
IPI
MmuMGI:1914719
GO:0016298 lipase activity F
IDA
AthAt4g24160
GO:0016787 hydrolase activity F
ISS
AthAt4g24160
GO:0042171 lysophosphatidic acid acyltransferase
activity		 F
IDA
AthAt4g24160
SceS000004089
GO:0006629 lipid metabolic process P
ISA
MmuMGI:1914719
ISO
MmuMGI:1914719
GO:0006654 phosphatidic acid biosynthetic
process		 P
IMP
SceS000004089
GO:0010891 negative regulation of sequestering of
triglyceride		 P
IDA
MmuMGI:1914719
GO:0010898 positive regulation of triglyceride catabolic
process		 P
IDA
MmuMGI:1914719
GO:0019915 lipid storage P
IMP
CelWBGene00016507
GO:0032048 cardiolipin metabolic process P
IDA
SceS000003342
IGI
SceS000003342
ISS
SpoSPAC6G10.03c
GO:0033554 cellular response to stress P
IEP
SpoSPAC6G10.03c
GO:0040011 locomotion P
IMP
CelWBGene00016507
GO:0051006 positive regulation of lipoprotein lipase
activity		 P
IDA
MmuMGI:1914719

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s.khadayate@ucl.ac.uk