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Search term: YLR106C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MDN1
SGD link S000004096
Alternative ID YLR106C
Description Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm
Synonyms YLR106C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1808 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED AAA ATPase containing von Willebrand factor type A (vWA) domain

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g67120 GI:15219832
Caenorhabditis elegans (Cel) CE17878 GI:17540648
Caenorhabditis elegans (Cel) CE20666 GI:17551594
Caenorhabditis elegans (Cel) CE20667 GI:17551592
Caenorhabditis elegans (Cel) CE28973 GI:17543012
Drosophila melanogaster (Dme) 7303557 GI:7303557
Drosophila melanogaster (Dme) 7303558 GI:7303558
Homo sapiens (Hsa) Hs22053093 GI:22053093
Homo sapiens (Hsa) Hs20552711 GI:20552711
Saccharomyces cerevisiae (Sce) YLR106c
(S000004096)
GI:6323135 Q12019
Schizosaccharomyces pombe (Spo) SPCC737.08 GI:19075870 O94248
Encephalitozoon cuniculi (Ecu) ECU08g1900 GI:19173514 Q8SUI9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004096
SpoSPCC737.08
ISS
SpoSPCC737.08
GO:0005654 nucleoplasm C
IDA
SceS000004096
GO:0005739 mitochondrion C
IDA
SceS000004096
GO:0005816 spindle pole body C
IDA
SpoSPCC737.08
GO:0009941 chloroplast envelope C
IDA
AthAt1g67120
GO:0005509 calcium ion binding F
ISS
SpoSPCC737.08
GO:0005524 ATP binding F
IC
SpoSPCC737.08
GO:0016887 ATPase activity F
ISS
SceS000004096
SpoSPCC737.08
GO:0000027 ribosomal large subunit assembly P
IMP
SceS000004096
IPI
SceS000004096
ISS
SpoSPCC737.08
GO:0006200 ATP catabolic process P
ISS
SpoSPCC737.08
GO:0006364 rRNA processing P
IMP
SceS000004096
ISS
SpoSPCC737.08
GO:0042255 ribosome assembly P
RCA
SceS000004096
GO:0042273 ribosomal large subunit biogenesis P
RCA
SceS000004096

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39689

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MDN1 GI:24415404
Pan troglodytes (Ptr) MDN1 GI:114608501
Canis familiaris (Cfa) MDN1 GI:73973473
Mus musculus (Mmu) Mdn1
(MGI:1926159)
GI:124487133 Q3TPE2
Gallus gallus (Gga) MDN1 GI:118088812
Drosophila melanogaster (Dme) CG13185
(FBgn0033661)
GI:161076562
Anopheles gambiae (Aga) AgaP_AGAP007388 GI:158285754
Schizosaccharomyces pombe (Spo) SPCC737.08 GI:19075870 O94248
Saccharomyces cerevisiae (Sce) MDN1
(S000004096)
GI:6323135 Q12019
Kluyveromyces lactis (Kla) KLLA0F19888g GI:50311883
Eremothecium gossypii (Ego) AGOS_AGR074C GI:45201169
Magnaporthe grisea (Mgr) MGG_06379 GI:145608786
Neurospora crassa (Ncr) NCU06468.1 GI:32411685
Arabidopsis thaliana (Ath) AT1G67120 GI:186493633
Oryza sativa (Osa) Os10g0456900 GI:115482330


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1926159
GO:0005634 nucleus C
IDA
SceS000004096
SpoSPCC737.08
ISS
SpoSPCC737.08
NAS
HsaMDN1
GO:0005654 nucleoplasm C
IDA
SceS000004096
GO:0005739 mitochondrion C
IDA
SceS000004096
GO:0005816 spindle pole body C
IDA
SpoSPCC737.08
GO:0009941 chloroplast envelope C
IDA
AthAt1g67120
GO:0003674 molecular_function F
ND
MmuMGI:1926159
GO:0005509 calcium ion binding F
ISS
SpoSPCC737.08
GO:0005524 ATP binding F
IC
SpoSPCC737.08
GO:0016887 ATPase activity F
ISS
SceS000004096
SpoSPCC737.08
NAS
HsaMDN1
GO:0051082 unfolded protein binding F
NAS
HsaMDN1
GO:0000027 ribosomal large subunit assembly P
IMP
SceS000004096
IPI
SceS000004096
ISS
SpoSPCC737.08
GO:0006200 ATP catabolic process P
ISS
SpoSPCC737.08
GO:0006364 rRNA processing P
IMP
SceS000004096
ISS
SpoSPCC737.08
GO:0006461 protein complex assembly P
NAS
HsaMDN1
GO:0008150 biological_process P
ND
MmuMGI:1926159
GO:0042255 ribosome assembly P
RCA
SceS000004096
GO:0042273 ribosomal large subunit biogenesis P
RCA
SceS000004096

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_788

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga2812 ENSANGP00000017898
Ashbya gossypii (Ago) ago4384 AGR074C
Arabidopsis thaliana (Ath) ath5945 At1g67120.1
Caenorhabditis elegans (Cel) cel10433 F55F10.1
(CE30377;
WBGene00018898)
Candida glabrata (Cgl) cgl5160 CAGL0M11616g
Cryptococcus neoformans (Cne) cne3897 185.m02485
Dictyostelium discoideum (Ddi) ddi3234 DDB0217682
Debaryomyces hansenii (Dha) dha3962 DEHA0E16291g
Debaryomyces hansenii (Dha) dha3965 DEHA0E16324g
Drosophila melanogaster (Dme) dme4557 CG13185-PA
(FBgn0033661)
Danio rerio (Dre) dre12576 ENSDARP00000018762
(DKEYP-117E10.5)
Danio rerio (Dre) dre12586 ENSDARP00000025022
(si:dkeyp-117e10.5)
Q5RII8
Encephalitozoon cuniculi (Ecu) ecu345 19173514
Takifugu rubripes (Fru) fru7199 SINFRUP00000149074
Takifugu rubripes (Fru) fru7201 SINFRUP00000174175
Gallus gallus (Gga) gga15682 ENSGALP00000025127
Gallus gallus (Gga) gga15683 ENSGALP00000025327
(MDN1)
Gallus gallus (Gga) gga15684 ENSGALP00000025365
Gallus gallus (Gga) gga15686 ENSGALP00000025367
Gallus gallus (Gga) gga15688 ENSGALP00000025370
Homo sapiens (Hsa) hsa27497 ENSP00000251742
Kluyveromyces lactis (Kla) kla4973 KLLA0F19888g
Mus musculus (Mmu) mmu17919 ENSMUSP00000029949
Mus musculus (Mmu) mmu17915 ENSMUSP00000076764
Mus musculus (Mmu) mmu17913 ENSMUSP00000079157
Neurospora crassa (Ncr) ncr6287 NCU06468.2
Oryza sativa (Osa) osa36538 4841.m00181
Plasmodium falciparum (Pfa) pfa1777 PF14_0326
Rattus norvegicus (Rno) rno22916 ENSRNOP00000009271
(GI:362498)
Q5RJZ0
Rattus norvegicus (Rno) rno22914 ENSRNOP00000039195
Saccharomyces cerevisiae (Sce) sce4188 YLR106C
(S000004096)
Schizosaccharomyces pombe (Spo) spo4355 SPCC737.08 O94248
Yarrowia lipolytica (Yli) yli1081 YALI0B08338g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004096
SpoSPCC737.08
ISS
SpoSPCC737.08
GO:0005654 nucleoplasm C
IDA
SceS000004096
GO:0005739 mitochondrion C
IDA
SceS000004096
GO:0005816 spindle pole body C
IDA
SpoSPCC737.08
GO:0009941 chloroplast envelope C
IDA
AthAt1g67120
GO:0005509 calcium ion binding F
ISS
SpoSPCC737.08
GO:0005524 ATP binding F
IC
SpoSPCC737.08
GO:0016887 ATPase activity F
ISS
SceS000004096
SpoSPCC737.08
GO:0000003 reproduction P
IMP
CelWBGene00018898
GO:0000027 ribosomal large subunit assembly P
IMP
SceS000004096
IPI
SceS000004096
ISS
SpoSPCC737.08
GO:0002119 nematode larval development P
IMP
CelWBGene00018898
GO:0006200 ATP catabolic process P
ISS
SpoSPCC737.08
GO:0006364 rRNA processing P
IMP
SceS000004096
ISS
SpoSPCC737.08
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00018898
GO:0040007 growth P
IMP
CelWBGene00018898
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00018898
GO:0040039 inductive cell migration P
IMP
CelWBGene00018898
GO:0042255 ribosome assembly P
RCA
SceS000004096
GO:0042273 ribosomal large subunit biogenesis P
RCA
SceS000004096

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC737.08
(O94248)
YLR106C
(S000004096)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004096
SpoSPCC737.08
ISS
SpoSPCC737.08
GO:0005654 nucleoplasm C
IDA
SceS000004096
GO:0005739 mitochondrion C
IDA
SceS000004096
GO:0005816 spindle pole body C
IDA
SpoSPCC737.08
GO:0005509 calcium ion binding F
ISS
SpoSPCC737.08
GO:0005524 ATP binding F
IC
SpoSPCC737.08
GO:0016887 ATPase activity F
ISS
SceS000004096
SpoSPCC737.08
GO:0000027 ribosomal large subunit assembly P
IMP
SceS000004096
IPI
SceS000004096
ISS
SpoSPCC737.08
GO:0006200 ATP catabolic process P
ISS
SpoSPCC737.08
GO:0006364 rRNA processing P
IMP
SceS000004096
ISS
SpoSPCC737.08
GO:0042255 ribosome assembly P
RCA
SceS000004096
GO:0042273 ribosomal large subunit biogenesis P
RCA
SceS000004096

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Query species:

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GO info in one table:

s.khadayate@ucl.ac.uk