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Search term: YLR128W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DCN1
SGD link S000004118
Alternative ID YLR128W
Description Scaffold-type E3 ligase required for cullin neddylation and ubiquitin ligase activation; contains a ubiquitin-binding domain (UBA) for ubiquitin and Nedd8 (Rub1p) interaction and a PONY domain involved in cullin binding and neddylation
Synonyms YLR128W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3077 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g15860 GI:15218337
Arabidopsis thaliana (Ath) At3g12760 GI:18399737
Arabidopsis thaliana (Ath) At3g28970 GI:15228555
Caenorhabditis elegans (Cel) CE23836 GI:17553918
Caenorhabditis elegans (Cel) CE23837 GI:17553916
Drosophila melanogaster (Dme) 7293667 GI:7293667
Drosophila melanogaster (Dme) 7294266 GI:7294266
Drosophila melanogaster (Dme) 7303381 GI:20129935
Homo sapiens (Hsa) Hs10190678 GI:10190678
Homo sapiens (Hsa) Hs8922603 GI:8922603
Homo sapiens (Hsa) Hs14725791 GI:14725791
Homo sapiens (Hsa) Hs17447631 GI:17447631
Homo sapiens (Hsa) Hs14150015
(DCUN1D5)		 GI:14150015 Q9BTE7
Saccharomyces cerevisiae (Sce) YLR128w
(S000004118)		 GI:6323157 Q12395
Schizosaccharomyces pombe (Spo) SPBC839.03c GI:19112035 Q8WZK4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g12760
SceS000004118
GO:0005634 nucleus C
IDA
SpoSPBC839.03c
ISS
AthAt3g28970
GO:0005829 cytosol C
IDA
SpoSPBC839.03c
GO:0003674 molecular_function F
ND
AthAt3g12760
At3g28970
GO:0008047 enzyme activator activity F
ISS
SpoSPBC839.03c
GO:0019788 NEDD8 ligase activity F
IDA
SceS000004118
IMP
SceS000004118
GO:0032182 small conjugating protein binding F
IDA
SceS000004118
GO:0043130 ubiquitin binding F
IDA
SceS000004118
GO:0008150 biological_process P
ND
AthAt1g15860
At3g12760
GO:0009734 auxin mediated signaling pathway P
IMP
AthAt3g28970
GO:0045116 protein neddylation P
IDA
SceS000004118
IGI
SceS000004118
IMP
SceS000004118
ISS
SpoSPBC839.03c
GO:0051443 positive regulation of ubiquitin-protein ligase
activity		 P
IMP
SceS000004118
IPI
SceS000004118
ISS
SpoSPBC839.03c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
10773

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DCUN1D1 GI:36030883
Pan troglodytes (Ptr) DCUN1D1 GI:114590611
Canis familiaris (Cfa) DCUN1D1 GI:74003224
Mus musculus (Mmu) Dcun1d1
(MGI:2150386)		 GI:86476044 Q3TMV8
Rattus norvegicus (Rno) Dcun1d1 GI:109464685
Gallus gallus (Gga) DCUN1D1 GI:71896947
Drosophila melanogaster (Dme) CG7427
(FBgn0036510)		 GI:24664675
Anopheles gambiae (Aga) AgaP_AGAP004420 GI:158292152
Saccharomyces cerevisiae (Sce) DCN1
(S000004118)		 GI:6323157 Q12395
Kluyveromyces lactis (Kla) KLLA0D16346g GI:50307603
Eremothecium gossypii (Ego) AGOS_AGL194C GI:45200903


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000151 ubiquitin ligase complex C
IDA
HsaDCUN1D1
GO:0005575 cellular_component C
ND
SceS000004118
GO:0005515 protein binding F
IPI
HsaDCUN1D1
GO:0019788 NEDD8 ligase activity F
IDA
SceS000004118
IMP
SceS000004118
GO:0032182 small conjugating protein binding F
IDA
SceS000004118
GO:0043130 ubiquitin binding F
IDA
SceS000004118
GO:0008150 biological_process P
ND
HsaDCUN1D1
GO:0045116 protein neddylation P
IDA
SceS000004118
IGI
SceS000004118
IMP
SceS000004118
GO:0051443 positive regulation of ubiquitin-protein ligase
activity		 P
IMP
SceS000004118
IPI
SceS000004118

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1908

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6963 ENSANGP00000016989
Ashbya gossypii (Ago) ago4118 AGL194C
Arabidopsis thaliana (Ath) ath13420 At3g12760.1
Caenorhabditis elegans (Cel) cel11490 H38K22.2a
(CE33527;
WBGene00010428)
Caenorhabditis elegans (Cel) cel11491 H38K22.2b
(CE33528)
Candida glabrata (Cgl) cgl4842 CAGL0M04257g
Cryptococcus neoformans (Cne) cne874 163.m06240
Dictyostelium discoideum (Ddi) ddi2782 DDB0168620
Dictyostelium discoideum (Ddi) ddi8228 DDB0188688
Debaryomyces hansenii (Dha) dha4615 DEHA0F05060g
Drosophila melanogaster (Dme) dme9626 CG7427-PA
(FBgn0036510)
Danio rerio (Dre) dre23801 ENSDARP00000044728
Danio rerio (Dre) dre25479 ENSDARP00000046549
Takifugu rubripes (Fru) fru3377 SINFRUP00000138429
Takifugu rubripes (Fru) fru16088 SINFRUP00000141869
Takifugu rubripes (Fru) fru27879 SINFRUP00000162932
Gallus gallus (Gga) gga23627 ENSGALP00000014299
Gallus gallus (Gga) gga23628 ENSGALP00000014300
(DCUN1D1)		 Q5ZKU1
Gallus gallus (Gga) gga2674 ENSGALP00000027113
(DCUN1D2)
Gallus gallus (Gga) gga2675 ENSGALP00000027114
Homo sapiens (Hsa) hsa23511 ENSP00000292782
(DCUN1D1)		 Q96GG9
Kluyveromyces lactis (Kla) kla2780 KLLA0D16346g
Mus musculus (Mmu) mmu16502 ENSMUSP00000029258
(MGI:2150386)		 Q3UT23
Mus musculus (Mmu) mmu6939 ENSMUSP00000052240
Neurospora crassa (Ncr) ncr5554 NCU05716.2
Oryza sativa (Osa) osa44883 5625.m00122
Oryza sativa (Osa) osa44939 5625.m00163
Oryza sativa (Osa) osa44940 5625.m00164
Rattus norvegicus (Rno) rno15933 ENSRNOP00000017710
(RGD:1309668)
Saccharomyces cerevisiae (Sce) sce4211 YLR128W
(S000004118)
Schizosaccharomyces pombe (Spo) spo1396 SPBC839.03c Q8WZK4
Yarrowia lipolytica (Yli) yli6437 YALI0F26147g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g12760
SceS000004118
GO:0005634 nucleus C
IDA
CelWBGene00010428
SpoSPBC839.03c
GO:0005737 cytoplasm C
IDA
CelWBGene00010428
GO:0005829 cytosol C
IDA
SpoSPBC839.03c
GO:0003674 molecular_function F
ND
AthAt3g12760
GO:0005515 protein binding F
IPI
CelWBGene00010428
GO:0008047 enzyme activator activity F
ISS
SpoSPBC839.03c
GO:0019788 NEDD8 ligase activity F
IDA
SceS000004118
IMP
SceS000004118
GO:0032182 small conjugating protein binding F
IDA
SceS000004118
GO:0043130 ubiquitin binding F
IDA
SceS000004118
GO:0000003 reproduction P
IMP
CelWBGene00010428
GO:0002119 nematode larval development P
IMP
CelWBGene00010428
GO:0008150 biological_process P
ND
AthAt3g12760
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010428
GO:0018991 oviposition P
IMP
CelWBGene00010428
GO:0030953 spindle astral microtubule organization P
IMP
CelWBGene00010428
GO:0040001 establishment of mitotic spindle
localization		 P
IMP
CelWBGene00010428
GO:0040007 growth P
IMP
CelWBGene00010428
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00010428
GO:0040011 locomotion P
IMP
CelWBGene00010428
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00010428
GO:0044254 multicellular organismal protein catabolic
process		 P
IGI
CelWBGene00010428
IMP
CelWBGene00010428
GO:0045116 protein neddylation P
IDA
SceS000004118
IGI
SceS000004118
IMP
CelWBGene00010428
SceS000004118
ISS
SpoSPBC839.03c
GO:0051443 positive regulation of ubiquitin-protein ligase
activity		 P
IMP
SceS000004118
IPI
SceS000004118
ISS
SpoSPBC839.03c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC839.03c
(Q8WZK4)		 YLR128W
(S000004118)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004118
GO:0005634 nucleus C
IDA
SpoSPBC839.03c
GO:0005829 cytosol C
IDA
SpoSPBC839.03c
GO:0008047 enzyme activator activity F
ISS
SpoSPBC839.03c
GO:0019788 NEDD8 ligase activity F
IDA
SceS000004118
IMP
SceS000004118
GO:0032182 small conjugating protein binding F
IDA
SceS000004118
GO:0043130 ubiquitin binding F
IDA
SceS000004118
GO:0045116 protein neddylation P
IDA
SceS000004118
IGI
SceS000004118
IMP
SceS000004118
ISS
SpoSPBC839.03c
GO:0051443 positive regulation of ubiquitin-protein ligase
activity		 P
IMP
SceS000004118
IPI
SceS000004118
ISS
SpoSPBC839.03c

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GO info in one table:

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