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Search term: YLR133W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CKI1
SGD link S000004123
Alternative ID YLR133W
Description Choline kinase, catalyzing the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway); exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway
Synonyms YLR133W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2686 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Choline kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g34100_2 GI:15218502
Arabidopsis thaliana (Ath) At1g71697 GI:15217543
Arabidopsis thaliana (Ath) At1g74320 GI:15221196
Arabidopsis thaliana (Ath) At4g09760 GI:15234032
Caenorhabditis elegans (Cel) CE00647 GI:17551794
Caenorhabditis elegans (Cel) CE00648 GI:17551796
Caenorhabditis elegans (Cel) CE00649 GI:17551798
Caenorhabditis elegans (Cel) CE17695
(WBGene00000514)
GI:17560074 Q9GZF3
Caenorhabditis elegans (Cel) CE20533
(WBGene00000509)
GI:17538854 O17610
Caenorhabditis elegans (Cel) CE27113
(WBGene00000510)
GI:17551102
Drosophila melanogaster (Dme) 7302122 GI:7302122
Homo sapiens (Hsa) Hs22043135_1 GI:22043135
Homo sapiens (Hsa) Hs4557455 GI:4557455
Homo sapiens (Hsa) Hs6978649
(CHKB)
GI:6978649 O15094
Saccharomyces cerevisiae (Sce) YDR147w
(S000002554)
GI:6320351 Q03764
Saccharomyces cerevisiae (Sce) YLR133w
(S000004123)
GI:6323162 P20485
Schizosaccharomyces pombe (Spo) SPAC13G7.12c GI:19114626 Q10276


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g74320
At1g71697
GO:0005634 nucleus C
IDA
SpoSPAC13G7.12c
GO:0005737 cytoplasm C
IDA
CelWBGene00000509
SceS000002554
S000004123
GO:0005829 cytosol C
IDA
SpoSPAC13G7.12c
ISS
SpoSPAC13G7.12c
GO:0005938 cell cortex C
IDA
CelWBGene00000509
GO:0004103 choline kinase activity F
IDA
HsaCHKB
SceS000004123
S000002554
IGI
SceS000004123
S000002554
IMP
SceS000004123
ISS
AthAt1g74320
At1g71697
At4g09760
SceS000002554
SpoSPAC13G7.12c
GO:0004305 ethanolamine kinase activity F
IDA
HsaCHKB
SceS000002554
IGI
SceS000002554
S000004123
IMP
SceS000002554
S000004123
ISS
SceS000002554
GO:0006646 phosphatidylethanolamine biosynthetic
process
P
IDA
HsaCHKB
IGI
SceS000004123
S000002554
IMP
SceS000004123
S000002554
GO:0006656 phosphatidylcholine biosynthetic
process
P
IGI
SceS000004123
S000002554
IMP
SceS000002554
S000004123
ISS
SpoSPAC13G7.12c
GO:0006657 CDP-choline pathway P
ISS
SpoSPAC13G7.12c
GO:0009611 response to wounding P
IEP
AthAt1g71697

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101618

Species Gene ID NCBI link UniProt link
Caenorhabditis elegans (Cel) cka-1
(CE20533;
WBGene00000509)
GI:17538854 O17610
Schizosaccharomyces pombe (Spo) SPAC13G7.12c GI:19114626 Q10276
Saccharomyces cerevisiae (Sce) CKI1
(S000004123)
GI:6323162 P20485
Kluyveromyces lactis (Kla) KLLA0D16500g GI:50307617
Eremothecium gossypii (Ego) AGOS_AGL199C GI:45200898
Magnaporthe grisea (Mgr) MGG_03007 GI:39971081
Neurospora crassa (Ncr) NCU03176.1 GI:32420337


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC13G7.12c
GO:0005737 cytoplasm C
IDA
CelWBGene00000509
SceS000004123
GO:0005829 cytosol C
IDA
SpoSPAC13G7.12c
ISS
SpoSPAC13G7.12c
GO:0005938 cell cortex C
IDA
CelWBGene00000509
GO:0004103 choline kinase activity F
IDA
SceS000004123
IGI
SceS000004123
IMP
SceS000004123
ISS
SpoSPAC13G7.12c
GO:0004305 ethanolamine kinase activity F
IGI
SceS000004123
IMP
SceS000004123
GO:0006646 phosphatidylethanolamine biosynthetic
process
P
IGI
SceS000004123
IMP
SceS000004123
GO:0006656 phosphatidylcholine biosynthetic
process
P
IGI
SceS000004123
IMP
SceS000004123
ISS
SpoSPAC13G7.12c
GO:0006657 CDP-choline pathway P
ISS
SpoSPAC13G7.12c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_386

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga9918 ENSANGP00000009976
Anopheles gambiae (Aga) aga9919 ENSANGP00000026054
Ashbya gossypii (Ago) ago4113 AGL199C
Arabidopsis thaliana (Ath) ath3555 At1g34100.1
Arabidopsis thaliana (Ath) ath6451 At1g71697.1
Arabidopsis thaliana (Ath) ath6741 At1g74320.1
Arabidopsis thaliana (Ath) ath18699 At4g09760.1
Arabidopsis thaliana (Ath) ath18700 At4g09760.2
Arabidopsis thaliana (Ath) ath18701 At4g09760.3
Caenorhabditis elegans (Cel) cel2918 C28D4.2
(CE20533;
WBGene00000509)
Caenorhabditis elegans (Cel) cel4574 C52B9.1
Candida glabrata (Cgl) cgl998 CAGL0E01309g
Candida glabrata (Cgl) cgl4847 CAGL0M04367g
Cryptococcus neoformans (Cne) cne408 162.m04523
Dictyostelium discoideum (Ddi) ddi2337 DDB0217612
Debaryomyces hansenii (Dha) dha2878 DEHA0D13035g
Drosophila melanogaster (Dme) dme3279 CG2201-PA
(FBgn0032955)
Drosophila melanogaster (Dme) dme3280 CG2201-PB
(FBgn0032955)
Drosophila melanogaster (Dme) dme3281 CG2201-PC
(FBgn0032955)
Danio rerio (Dre) dre8739 ENSDARP00000039911
Danio rerio (Dre) dre9224 ENSDARP00000040195
(LOC558499)
Danio rerio (Dre) dre8740 ENSDARP00000040611
Danio rerio (Dre) dre9234 ENSDARP00000046697
Danio rerio (Dre) dre8742 ENSDARP00000048965
Takifugu rubripes (Fru) fru2339 SINFRUP00000135201
Takifugu rubripes (Fru) fru2337 SINFRUP00000135203
Takifugu rubripes (Fru) fru10402 SINFRUP00000136229
Takifugu rubripes (Fru) fru10403 SINFRUP00000136230
Takifugu rubripes (Fru) fru2338 SINFRUP00000166499
Takifugu rubripes (Fru) fru10401 SINFRUP00000175806
Gallus gallus (Gga) gga18959 ENSGALP00000011194
Gallus gallus (Gga) gga18960 ENSGALP00000011195
Gallus gallus (Gga) gga18958 ENSGALP00000011197
(CHKA)
Homo sapiens (Hsa) hsa6105 ENSP00000265689
(CHKA)
P35790-1
Homo sapiens (Hsa) hsa21944 ENSP00000312189
(CPT1B)
Q92523-1
Homo sapiens (Hsa) hsa6104 ENSP00000348454
(CHKA)
P35790-2
Kluyveromyces lactis (Kla) kla2787 KLLA0D16500g
Mus musculus (Mmu) mmu9498 ENSMUSP00000023289
(MGI:1328313)
O55229
Mus musculus (Mmu) mmu13030 ENSMUSP00000025760
(MGI:107760)
O54804-1
Mus musculus (Mmu) mmu13031 ENSMUSP00000071933
(MGI:107760)
O54804-2
Neurospora crassa (Ncr) ncr3078 NCU03176.2
Oryza sativa (Osa) osa9824 2713.m00106
Oryza sativa (Osa) osa14980 2981.m00127
Oryza sativa (Osa) osa31441 4384.m00160
Oryza sativa (Osa) osa35612 4732.m00299
Oryza sativa (Osa) osa77906 7477.m00076
Plasmodium falciparum (Pfa) pfa1240 PF14_0020
Rattus norvegicus (Rno) rno27601 ENSRNOP00000015374
(RGD:61826)
O54783
Rattus norvegicus (Rno) rno3407 ENSRNOP00000022824
(RGD:61944)
Q01134-2
Rattus norvegicus (Rno) rno3406 ENSRNOP00000023020
(RGD:61944)
Q01134-1
Saccharomyces cerevisiae (Sce) sce1185 YDR147W
(S000002554)
Saccharomyces cerevisiae (Sce) sce4216 YLR133W
(S000004123)
Schizosaccharomyces pombe (Spo) spo4697 SPAC13G7.12c Q10276
Yarrowia lipolytica (Yli) yli4559 YALI0E16907g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g74320
At1g71697
PfaPF14_0020
GO:0005634 nucleus C
IDA
SpoSPAC13G7.12c
GO:0005737 cytoplasm C
IDA
CelWBGene00000509
SceS000002554
S000004123
GO:0005829 cytosol C
IDA
SpoSPAC13G7.12c
ISS
SpoSPAC13G7.12c
GO:0005938 cell cortex C
IDA
CelWBGene00000509
GO:0004103 choline kinase activity F
IDA
MmuMGI:107760
SceS000004123
S000002554
IGI
SceS000004123
S000002554
IMP
MmuMGI:1328313
SceS000004123
ISO
MmuMGI:107760
MGI:1328313
ISS
AthAt1g74320
At1g71697
At4g09760
DmeFBgn0032955
PfaPF14_0020
SceS000002554
SpoSPAC13G7.12c
NAS
DmeFBgn0032955
GO:0004104 cholinesterase activity F
IDA
MmuMGI:107760
GO:0004305 ethanolamine kinase activity F
IDA
SceS000002554
IGI
SceS000002554
S000004123
IMP
SceS000002554
S000004123
ISS
SceS000002554
NAS
DmeFBgn0032955
GO:0005524 ATP binding F
ISO
MmuMGI:107760
GO:0033265 choline binding F
ISO
MmuMGI:107760
GO:0042803 protein homodimerization activity F
IPI
MmuMGI:107760
GO:0006629 lipid metabolic process P
ISS
PfaPF14_0020
GO:0006646 phosphatidylethanolamine biosynthetic
process
P
IGI
SceS000004123
S000002554
IMP
SceS000004123
S000002554
GO:0006656 phosphatidylcholine biosynthetic
process
P
IDA
MmuMGI:107760
IGI
SceS000004123
S000002554
IMP
MmuMGI:1328313
SceS000002554
S000004123
ISS
SpoSPAC13G7.12c
GO:0006657 CDP-choline pathway P
IDA
MmuMGI:107760
IMP
MmuMGI:1328313
ISS
SpoSPAC13G7.12c
GO:0007517 muscle organ development P
IMP
MmuMGI:1328313
GO:0009611 response to wounding P
IEP
AthAt1g71697
GO:0016310 phosphorylation P
IDA
MmuMGI:107760
IMP
MmuMGI:1328313
NAS
DmeFBgn0032955
GO:0019695 choline metabolic process P
ISO
MmuMGI:107760

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC13G7.12c
(Q10276)
YLR133W
(S000004123)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC13G7.12c
GO:0005737 cytoplasm C
IDA
SceS000004123
GO:0005829 cytosol C
IDA
SpoSPAC13G7.12c
ISS
SpoSPAC13G7.12c
GO:0004103 choline kinase activity F
IDA
SceS000004123
IGI
SceS000004123
IMP
SceS000004123
ISS
SpoSPAC13G7.12c
GO:0004305 ethanolamine kinase activity F
IGI
SceS000004123
IMP
SceS000004123
GO:0006646 phosphatidylethanolamine biosynthetic
process
P
IGI
SceS000004123
IMP
SceS000004123
GO:0006656 phosphatidylcholine biosynthetic
process
P
IGI
SceS000004123
IMP
SceS000004123
ISS
SpoSPAC13G7.12c
GO:0006657 CDP-choline pathway P
ISS
SpoSPAC13G7.12c

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Search for gene by ID or name:

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GO info in one table:

s.khadayate@ucl.ac.uk