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Search term: YLR135W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SLX4
SGD link S000004125
Alternative ID YLR135W
Description Endonuclease involved in processing DNA during recombination and repair; cleaves branched structures in a complex with Slx1p; involved in Rad1p/Rad10p-dependent removal of 3'-nonhomologous tails during DSBR via single-strand annealing
Synonyms YLR135W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48896

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SLX4
(S000004125)		 GI:6323164
Kluyveromyces lactis (Kla) KLLA0D16544g GI:50307621
Eremothecium gossypii (Ego) AGOS_AGR042W GI:45201137


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000004125
IMP
SceS000004125
GO:0033557 Slx1-Slx4 complex C
IPI
SceS000004125
GO:0017108 5'-flap endonuclease activity F
IDA
SceS000004125
GO:0000736 double-strand break repair via single-strand
annealing, removal of nonhomologous
ends		 P
IGI
SceS000004125
IMP
SceS000004125
GO:0006260 DNA replication P
IMP
SceS000004125
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000004125
GO:0006974 response to DNA damage stimulus P
IGI
SceS000004125

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24617

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago4352 AGR042W
Candida glabrata (Cgl) cgl4848 CAGL0M04389g
Debaryomyces hansenii (Dha) dha3982 DEHA0E16731g
Kluyveromyces lactis (Kla) kla2789 KLLA0D16544g
Saccharomyces cerevisiae (Sce) sce4218 YLR135W
(S000004125)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000004125
IMP
SceS000004125
GO:0033557 Slx1-Slx4 complex C
IPI
SceS000004125
GO:0017108 5'-flap endonuclease activity F
IDA
SceS000004125
GO:0000736 double-strand break repair via single-strand
annealing, removal of nonhomologous
ends		 P
IGI
SceS000004125
IMP
SceS000004125
GO:0006260 DNA replication P
IMP
SceS000004125
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000004125
GO:0006974 response to DNA damage stimulus P
IGI
SceS000004125

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC688.06c
(Q9P6M0)		 YLR135W
(S000004125)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000004125
IDA
SpoSPAC688.06c
IMP
SceS000004125
GO:0030874 nucleolar chromatin C
IDA
SpoSPAC688.06c
GO:0033557 Slx1-Slx4 complex C
IDA
SpoSPAC688.06c
IPI
SceS000004125
GO:0004519 endonuclease activity F
IMP
SpoSPAC688.06c
GO:0005515 protein binding F
IPI
SpoSPAC688.06c
GO:0017108 5'-flap endonuclease activity F
IDA
SceS000004125
GO:0000736 double-strand break repair via single-strand
annealing, removal of nonhomologous
ends		 P
IGI
SceS000004125
IMP
SceS000004125
GO:0006260 DNA replication P
IMP
SceS000004125
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000004125
ISS
SpoSPAC688.06c
GO:0006974 response to DNA damage stimulus P
IGI
SceS000004125
GO:0031297 replication fork processing P
TAS
SpoSPAC688.06c
GO:0034065 replication fork processing at rDNA
locus		 P
TAS
SpoSPAC688.06c
GO:0043007 maintenance of rDNA P
IMP
SpoSPAC688.06c

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