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Search term: YLR146C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SPE4
SGD link S000004136
Alternative ID YLR146C
Description Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid
Synonyms YLR146C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1562 ACDHYP-

KOGs classification KOGs description
METABOLISM Spermidine synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g23820 GI:15220885
Arabidopsis thaliana (Ath) At1g70310 GI:15223115
Arabidopsis thaliana (Ath) At5g19530 GI:15239770
Arabidopsis thaliana (Ath) At5g53120 GI:9757993
Caenorhabditis elegans (Cel) CE21997 GI:17537153
Drosophila melanogaster (Dme) 7294595 GI:7294595
Drosophila melanogaster (Dme) 7294596 GI:7294596
Drosophila melanogaster (Dme) 7299220 GI:7299220 Q9VHA1
Drosophila melanogaster (Dme) 7299221 GI:7299221
Homo sapiens (Hsa) Hs21264341 GI:8247960 P52788
Homo sapiens (Hsa) Hs20545353 GI:20545353
Homo sapiens (Hsa) Hs4507209 GI:4507209
Homo sapiens (Hsa) HsM4759152 GI:4759152
Saccharomyces cerevisiae (Sce) YLR146c
(S000004136)		 GI:6323175 Q12455
Saccharomyces cerevisiae (Sce) YPR069c
(S000006273)		 GI:6325326 Q12074
Schizosaccharomyces pombe (Spo) SPBC12C2.07c GI:19112807 Q09741


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g23820
GO:0005634 nucleus C
IDA
SceS000006273
SpoSPBC12C2.07c
ISS
SpoSPBC12C2.07c
GO:0005737 cytoplasm C
IDA
SceS000004136
S000006273
ISS
SpoSPBC12C2.07c
TAS
AthAt5g19530
At5g53120
GO:0005829 cytosol C
IDA
SpoSPBC12C2.07c
GO:0005886 plasma membrane C
IDA
AthAt1g70310
GO:0004766 spermidine synthase activity F
IDA
AthAt1g23820
At5g53120
At1g70310
IMP
SceS000006273
ISS
AthAt5g53120
SceS000006273
SpoSPBC12C2.07c
GO:0010487 thermospermine synthase activity F
IDA
AthAt5g19530
GO:0016768 spermine synthase activity F
IDA
AthAt5g19530
At5g53120
IMP
SceS000004136
GO:0006596 polyamine biosynthetic process P
IDA
AthAt5g53120
GO:0006597 spermine biosynthetic process P
IMP
SceS000004136
GO:0008295 spermidine biosynthetic process P
IDA
AthAt1g23820
At1g70310
IMP
SceS000006273
ISS
SpoSPBC12C2.07c
GO:0009826 unidimensional cell growth P
IGI
AthAt5g19530
GO:0009926 auxin polar transport P
IMP
AthAt5g19530
GO:0010087 phloem or xylem histogenesis P
IMP
AthAt5g19530
GO:0015940 pantothenate biosynthetic process P
IMP
SceS000006273
S000004136
ISS
SpoSPBC12C2.07c
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004136
GO:0048759 vessel member cell differentiation P
IMP
AthAt5g19530

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
74752

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SPE4
(S000004136)		 GI:6323175 Q12455
Kluyveromyces lactis (Kla) KLLA0D17094g GI:50307673


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000004136
GO:0016768 spermine synthase activity F
IMP
SceS000004136
GO:0006597 spermine biosynthetic process P
IMP
SceS000004136
GO:0015940 pantothenate biosynthetic process P
IMP
SceS000004136
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004136

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_684

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8151 ENSANGP00000012620
Ashbya gossypii (Ago) ago1400 ADL340W
Arabidopsis thaliana (Ath) ath2563 At1g23820.1
Arabidopsis thaliana (Ath) ath2564 At1g23820.2
Arabidopsis thaliana (Ath) ath6305 At1g70310.1
Arabidopsis thaliana (Ath) ath24226 At5g19530.1
Caenorhabditis elegans (Cel) cel19001 Y46G5A.19
(CE31114;
WBGene00012909)
Candida glabrata (Cgl) cgl721 CAGL0D01408g
Candida glabrata (Cgl) cgl4858 CAGL0M04609g
Cryptococcus neoformans (Cne) cne4207 177.m02965
Dictyostelium discoideum (Ddi) ddi11582 DDB0191167
Debaryomyces hansenii (Dha) dha2804 DEHA0D11418g
Debaryomyces hansenii (Dha) dha3999 DEHA0E17149g
Drosophila melanogaster (Dme) dme11748 CG8327-PA
(FBgn0037723)
Drosophila melanogaster (Dme) dme11749 CG8327-PB
(FBgn0037723)
Danio rerio (Dre) dre15527 ENSDARP00000025783
Escherichia coli (Eco) eco122 16128114
Takifugu rubripes (Fru) fru12626 SINFRUP00000152096
Gallus gallus (Gga) gga12522 ENSGALP00000004799
(SRM)
Homo sapiens (Hsa) hsa264 ENSP00000235287
Kluyveromyces lactis (Kla) kla943 KLLA0B09372g
Kluyveromyces lactis (Kla) kla2815 KLLA0D17094g
Mus musculus (Mmu) mmu19438 ENSMUSP00000006611
(MGI:102690)		 Q64674
Neurospora crassa (Ncr) ncr6543 NCU06727.2
Oryza sativa (Osa) osa3553 2049.m00079
Oryza sativa (Osa) osa6126 2440.m00221
Oryza sativa (Osa) osa52305 5937.m00270
Oryza sativa (Osa) osa56365 6189.m00120
Oryza sativa (Osa) osa56382 6189.m00159
Plasmodium falciparum (Pfa) pfa752 PF11_0301
Rattus norvegicus (Rno) rno24420 ENSRNOP00000014934
(RGD:620796)		 Q99MI5
Saccharomyces cerevisiae (Sce) sce4229 YLR146C
(S000004136)
Saccharomyces cerevisiae (Sce) sce6524 YPR069C
(S000006273)
Schizosaccharomyces pombe (Spo) spo165 SPBC12C2.07c Q09741
Yarrowia lipolytica (Yli) yli4060 YALI0E04763g
Yarrowia lipolytica (Yli) yli5242 YALI0E33143g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g23820
DmeFBgn0037723
PfaPF11_0301
GO:0005634 nucleus C
IDA
SceS000006273
SpoSPBC12C2.07c
ISS
SpoSPBC12C2.07c
GO:0005737 cytoplasm C
IDA
SceS000004136
S000006273
ISS
SpoSPBC12C2.07c
TAS
AthAt5g19530
GO:0005829 cytosol C
IDA
SpoSPBC12C2.07c
GO:0005886 plasma membrane C
IDA
AthAt1g70310
GO:0004766 spermidine synthase activity F
IDA
AthAt1g23820
At1g70310
IMP
SceS000006273
ISO
MmuMGI:102690
ISS
DmeFBgn0037723
PfaPF11_0301
SceS000006273
SpoSPBC12C2.07c
GO:0010487 thermospermine synthase activity F
IDA
AthAt5g19530
GO:0016768 spermine synthase activity F
IDA
AthAt5g19530
IMP
SceS000004136
GO:0006597 spermine biosynthetic process P
IMP
SceS000004136
GO:0008295 spermidine biosynthetic process P
IDA
AthAt1g23820
At1g70310
IMP
SceS000006273
ISO
MmuMGI:102690
ISS
DmeFBgn0037723
PfaPF11_0301
SpoSPBC12C2.07c
GO:0009826 unidimensional cell growth P
IGI
AthAt5g19530
GO:0009926 auxin polar transport P
IMP
AthAt5g19530
GO:0010087 phloem or xylem histogenesis P
IMP
AthAt5g19530
GO:0015940 pantothenate biosynthetic process P
IMP
SceS000006273
S000004136
ISS
SpoSPBC12C2.07c
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004136
GO:0048759 vessel member cell differentiation P
IMP
AthAt5g19530

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC12C2.07c
(Q09741)		 YLR146C
(S000004136)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC12C2.07c
ISS
SpoSPBC12C2.07c
GO:0005737 cytoplasm C
IDA
SceS000004136
ISS
SpoSPBC12C2.07c
GO:0005829 cytosol C
IDA
SpoSPBC12C2.07c
GO:0004766 spermidine synthase activity F
ISS
SpoSPBC12C2.07c
GO:0016768 spermine synthase activity F
IMP
SceS000004136
GO:0006597 spermine biosynthetic process P
IMP
SceS000004136
GO:0008295 spermidine biosynthetic process P
ISS
SpoSPBC12C2.07c
GO:0015940 pantothenate biosynthetic process P
IMP
SceS000004136
ISS
SpoSPBC12C2.07c
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004136

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GO info in one table:

s.khadayate@ucl.ac.uk