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Search term: YLR174W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name IDP2
SGD link S000004164
Alternative ID YLR174W
Description Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose
Synonyms YLR174W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1526 ACDHYP-

KOGs classification KOGs description
METABOLISM NADP-dependent isocitrate dehydrogenase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g54340 GI:15221788
Arabidopsis thaliana (Ath) At1g65930 GI:15218869
Arabidopsis thaliana (Ath) At5g14590 GI:15241443
Caenorhabditis elegans (Cel) CE03436
(WBGene00010317)		 GI:17540874 Q21032
Caenorhabditis elegans (Cel) CE15677
(WBGene00007942)		 GI:17550822 O17643
Drosophila melanogaster (Dme) 7295108 GI:7295108 Q7KUB1
Homo sapiens (Hsa) Hs5174471 GI:5174471
Homo sapiens (Hsa) Hs4504575 GI:4504575
Homo sapiens (Hsa) Hs14729950 GI:14729950
Homo sapiens (Hsa) Hs17463070 GI:17463070
Saccharomyces cerevisiae (Sce) YDL066w
(S000002224)		 GI:6320137 P21954
Saccharomyces cerevisiae (Sce) YLR174w
(S000004164)		 GI:6323203 P41939
Saccharomyces cerevisiae (Sce) YNL009w
(S000004954)		 GI:6324319 P53982
Schizosaccharomyces pombe (Spo) SPAC6G10.08 GI:19115017 O14254


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000004954
ISS
SpoSPAC6G10.08
GO:0005739 mitochondrion C
IDA
AthAt5g14590
SceS000002224
S000004954
SpoSPAC6G10.08
ISS
SpoSPAC6G10.08
GO:0005777 peroxisome C
IDA
AthAt1g54340
SceS000004954
TAS
SceS000004954
GO:0005829 cytosol C
IDA
SceS000004164
NAS
AthAt1g65930
GO:0005886 plasma membrane C
IDA
AthAt1g65930
At1g54340
GO:0009507 chloroplast C
IDA
AthAt5g14590
GO:0042645 mitochondrial nucleoid C
IDA
SceS000002224
GO:0048046 apoplast C
IDA
AthAt1g65930
GO:0004450 isocitrate dehydrogenase (NADP+)
activity		 F
IMP
AthAt1g65930
ISS
AthAt1g65930
At5g14590
At1g54340
SpoSPAC6G10.08
TAS
SceS000002224
S000004164
S000004954
GO:0005507 copper ion binding F
IDA
AthAt1g65930
GO:0006082 organic acid metabolic process P
RCA
SceS000002224
GO:0006099 tricarboxylic acid cycle P
IC
SpoSPAC6G10.08
GO:0006102 isocitrate metabolic process P
IGI
SceS000004164
IMP
AthAt1g65930
SceS000004164
ISS
SpoSPAC6G10.08
TAS
SceS000002224
S000004954
GO:0006414 translational elongation P
RCA
SceS000002224
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000002224
GO:0006537 glutamate biosynthetic process P
IGI
SceS000002224
IMP
SceS000002224
ISS
SpoSPAC6G10.08
TAS
SceS000004164
GO:0006635 fatty acid beta-oxidation P
IMP
SceS000004954
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000002224
GO:0006739 NADP metabolic process P
IMP
AthAt1g65930
GO:0006740 NADPH regeneration P
ISS
SpoSPAC6G10.08
TAS
SceS000004954
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000002224
GO:0008152 metabolic process P
ISS
AthAt1g65930
At1g54340
At5g14590
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00010317
GO:0009651 response to salt stress P
IEP
AthAt1g65930
GO:0010043 response to zinc ion P
IEP
AthAt1g65930
GO:0042742 defense response to bacterium P
IMP
AthAt1g65930
GO:0046686 response to cadmium ion P
IEP
AthAt1g65930
GO:0055114 oxidation reduction P
RCA
SceS000002224

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
37590

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) IDH2 GI:28178832
Pan troglodytes (Ptr) IDH2 GI:114658862
Canis familiaris (Cfa) IDH2 GI:73951496
Mus musculus (Mmu) Idh2
(MGI:96414)		 GI:27370516 P54071
Rattus norvegicus (Rno) Idh2 GI:62079055
Anopheles gambiae (Aga) AgaP_AGAP003168 GI:158291350
Caenorhabditis elegans (Cel) C34F6.8
(CE15677;
WBGene00007942)		 GI:17550822 O17643
Saccharomyces cerevisiae (Sce) IDP2
(S000004164)		 GI:6323203 P41939
Kluyveromyces lactis (Kla) KLLA0F12342g GI:50311227
Eremothecium gossypii (Ego) AGOS_AAL022W GI:45184802
Arabidopsis thaliana (Ath) ICDH GI:15221788
Oryza sativa (Osa) Os01g0248400 GI:115435650
Plasmodium falciparum (Pfa) PF13_0242 GI:124513630


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
HsaIDH2
MmuMGI:96414
ISS
PfaPF13_0242
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:96414
GO:0005777 peroxisome C
IDA
AthICDH
GO:0005829 cytosol C
IDA
SceS000004164
NAS
AthICDH
GO:0005886 plasma membrane C
IDA
AthICDH
GO:0000287 magnesium ion binding F
ISS
HsaIDH2
GO:0004450 isocitrate dehydrogenase (NADP+)
activity		 F
IDA
MmuMGI:96414
IMP
AthICDH
ISS
AthICDH
HsaIDH2
TAS
SceS000004164
GO:0005975 carbohydrate metabolic process P
NAS
HsaIDH2
GO:0006102 isocitrate metabolic process P
IGI
SceS000004164
IMP
AthICDH
SceS000004164
ISS
HsaIDH2
PfaPF13_0242
GO:0006103 2-oxoglutarate metabolic process P
ISS
HsaIDH2
GO:0006537 glutamate biosynthetic process P
TAS
SceS000004164
GO:0006739 NADP metabolic process P
IMP
AthICDH
GO:0008152 metabolic process P
IDA
MmuMGI:96414
ISS
AthICDH
GO:0010043 response to zinc ion P
IEP
AthICDH
GO:0042742 defense response to bacterium P
IMP
AthICDH

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_450

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5457 ENSANGP00000016660
Anopheles gambiae (Aga) aga2108 ENSANGP00000020939
Ashbya gossypii (Ago) ago165 AAL022W
Ashbya gossypii (Ago) ago2566 AER061C
Arabidopsis thaliana (Ath) ath4747 At1g54340.1
Arabidopsis thaliana (Ath) ath5813 At1g65930.1
Arabidopsis thaliana (Ath) ath23668 At5g14590.1
Caenorhabditis elegans (Cel) cel3449 C34F6.8
(CE15677;
WBGene00007942)
Caenorhabditis elegans (Cel) cel11065 F59B8.2
(CE03436;
WBGene00010317)
Candida glabrata (Cgl) cgl418 CAGL0B04917g
Candida glabrata (Cgl) cgl692 CAGL0D00770g
Candida glabrata (Cgl) cgl2220 CAGL0H03663g
Cryptococcus neoformans (Cne) cne4937 186.m03846
Cryptococcus neoformans (Cne) cne4938 186.m03847
Dictyostelium discoideum (Ddi) ddi11606 DDB0231401
Dictyostelium discoideum (Ddi) ddi11607 DDB0231402
Debaryomyces hansenii (Dha) dha3740 DEHA0E11286g
Debaryomyces hansenii (Dha) dha4302 DEHA0E24134g
Drosophila melanogaster (Dme) dme8548 CG7176-PA
(FBgn0001248)
Drosophila melanogaster (Dme) dme8551 CG7176-PB
(FBgn0001248)
Drosophila melanogaster (Dme) dme8552 CG7176-PC
(FBgn0001248)
Drosophila melanogaster (Dme) dme8553 CG7176-PD
(FBgn0001248)
Drosophila melanogaster (Dme) dme8554 CG7176-PE
(FBgn0001248)
Drosophila melanogaster (Dme) dme8549 CG7176-PF
(FBgn0001248)
Drosophila melanogaster (Dme) dme8550 CG7176-PG
(FBgn0001248)
Danio rerio (Dre) dre31106 ENSDARP00000023774
(idh1)		 Q802Y2
Danio rerio (Dre) dre17641 ENSDARP00000027389
(idh2)		 Q7ZUP6
Takifugu rubripes (Fru) fru7773 SINFRUP00000128662
Takifugu rubripes (Fru) fru17111 SINFRUP00000145570
Takifugu rubripes (Fru) fru16011 SINFRUP00000170653
Gallus gallus (Gga) gga21409 ENSGALP00000014317
(IDH1)
Homo sapiens (Hsa) hsa19199 ENSP00000260985
(IDH1)		 O75874
Homo sapiens (Hsa) hsa11174 ENSP00000331897
(IDH2)		 P48735
Kluyveromyces lactis (Kla) kla681 KLLA0B03355g
Kluyveromyces lactis (Kla) kla4638 KLLA0F12342g
Mus musculus (Mmu) mmu472 ENSMUSP00000027087
(MGI:96413)		 Q8C338
Mus musculus (Mmu) mmu24236 ENSMUSP00000053273
(MGI:96414)
Neurospora crassa (Ncr) ncr3746 NCU03857.2
Oryza sativa (Osa) osa8630 2643.m00157
Oryza sativa (Osa) osa9324 2702.m00151
Oryza sativa (Osa) osa14151 2881.m00154
Oryza sativa (Osa) osa17842 3321.m00205
Oryza sativa (Osa) osa264 34.m00165
Plasmodium falciparum (Pfa) pfa4425 PF13_0242
Rattus norvegicus (Rno) rno2162 ENSRNOP00000019059
(RGD:1597139)		 P56574
Rattus norvegicus (Rno) rno30167 ENSRNOP00000020322
(RGD:2862)		 P41562
Rattus norvegicus (Rno) rno30168 ENSRNOP00000044421
(RGD:2862)
Rattus norvegicus (Rno) rno2163 ENSRNOP00000045554
Saccharomyces cerevisiae (Sce) sce836 YDL066W
(S000002224)
Saccharomyces cerevisiae (Sce) sce4274 YLR174W
(S000004164)
Schizosaccharomyces pombe (Spo) spo3267 SPAC6G10.08 O14254
Yarrowia lipolytica (Yli) yli5514 YALI0F04095g