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Search term: YLR175W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CBF5
SGD link S000004165
Alternative ID YLR175W
Description Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), acts on both large and small rRNAs and on snRNA U2; mutations in human ortholog dyskerin cause the disorder dyskeratosis congenita
Synonyms YLR175W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2529 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Pseudouridine synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g57150 GI:15230232
Arabidopsis thaliana (Ath) At5g14460 GI:15241405
Caenorhabditis elegans (Cel) CE16195
(WBGene00010478)		 GI:17553978 O17919
Drosophila melanogaster (Dme) 7291757 GI:17975520
Homo sapiens (Hsa) Hs4503337
(DKC1)		 GI:4503337 O60832
Homo sapiens (Hsa) Hs21040257 GI:18575011
Saccharomyces cerevisiae (Sce) YLR175w
(S000004165)		 GI:6323204 P33322
Saccharomyces cerevisiae (Sce) YNL292w
(S000005236)		 GI:6324037 P48567
Schizosaccharomyces pombe (Spo) SPAC29A4.04c GI:19115790 O14007
Schizosaccharomyces pombe (Spo) SPBC11C11.10 GI:19113192 O59721
Encephalitozoon cuniculi (Ecu) ECU05g1020 GI:19173642 Q8SRW0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaDKC1
SpoSPBC11C11.10
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0005654 nucleoplasm C
EXP
HsaDKC1
GO:0005697 telomerase holoenzyme complex C
IDA
HsaDKC1
GO:0005730 nucleolus C
IC
SceS000004165
IDA
AthAt3g57150
HsaDKC1
GO:0005732 small nucleolar ribonucleoprotein
complex		 C
ISS
SpoSPAC29A4.04c
GO:0005739 mitochondrion C
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0005829 cytosol C
IDA
AthAt3g57150
SpoSPAC29A4.04c
GO:0030686 90S preribosome C
IDA
SceS000004165
GO:0031429 box H/ACA snoRNP complex C
IPI
SceS000004165
GO:0003720 telomerase activity F
IDA
HsaDKC1
GO:0004730 pseudouridylate synthase activity F
IMP
SceS000004165
ISS
SceS000004165
SpoSPAC29A4.04c
GO:0005215 transporter activity F
ISS
AthAt5g14460
GO:0005515 protein binding F
IPI
HsaDKC1
GO:0009982 pseudouridine synthase activity F
IDA
SceS000005236
S000004165
IGI
SceS000005236
ISS
AthAt3g57150
SpoSPBC11C11.10
TAS
AthAt5g14460
At3g57150
GO:0000003 reproduction P
IMP
CelWBGene00010478
GO:0000154 rRNA modification P
ISS
SpoSPAC29A4.04c
GO:0000495 box H/ACA snoRNA 3'-end processing P
IMP
SceS000004165
GO:0002119 nematode larval development P
IMP
CelWBGene00010478
GO:0006364 rRNA processing P
IMP
SceS000004165
ISS
SpoSPAC29A4.04c
GO:0006399 tRNA metabolic process P
NAS
SpoSPAC29A4.04c
GO:0006400 tRNA modification P
IDA
SceS000005236
GO:0007004 telomere maintenance via telomerase P
TAS
HsaDKC1
GO:0008283 cell proliferation P
TAS
HsaDKC1
GO:0009451 RNA modification P
ISS
AthAt5g14460
GO:0031118 rRNA pseudouridine synthesis P
IMP
SceS000004165
GO:0031119 tRNA pseudouridine synthesis P
IC
SpoSPBC11C11.10
GO:0031120 snRNA pseudouridine synthesis P
IDA
SceS000004165
IMP
SceS000004165
GO:0040007 growth P
IMP
CelWBGene00010478
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00010478

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1045

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DKC1 GI:4503337 O60832
Pan troglodytes (Ptr) DKC1 GI:114690728
Canis familiaris (Cfa) DKC1 GI:74009203
Mus musculus (Mmu) Dkc1
(MGI:1861727)		 GI:91064867 Q3TI79
Gallus gallus (Gga) DKC1 GI:71895397
Drosophila melanogaster (Dme) Nop60B
(FBgn0023184)		 GI:62471759
Anopheles gambiae (Aga) AgaP_AGAP004739 GI:158297969
Caenorhabditis elegans (Cel) K01G5.5
(CE16195;
WBGene00010478)		 GI:17553978 O17919
Schizosaccharomyces pombe (Spo) SPAC29A4.04c GI:19115790 O14007
Saccharomyces cerevisiae (Sce) CBF5
(S000004165)		 GI:6323204 P33322
Kluyveromyces lactis (Kla) CBF5_KLULA GI:50306599
Eremothecium gossypii (Ego) AGOS_AAL007C GI:45184817
Magnaporthe grisea (Mgr) MGG_07518 GI:145609335
Neurospora crassa (Ncr) NCU01290.1 GI:32412606
Arabidopsis thaliana (Ath) NAP57 GI:15230232
Oryza sativa (Osa) Os07g0636000 GI:115473585
Oryza sativa (Osa) Os03g0370500 GI:115453197
Plasmodium falciparum (Pfa) PF14_0174 GI:124808563


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF14_0174
GO:0005634 nucleus C
IDA
HsaDKC1
GO:0005654 nucleoplasm C
EXP
HsaDKC1
GO:0005697 telomerase holoenzyme complex C
IDA
HsaDKC1
GO:0005730 nucleolus C
IC
MmuMGI:1861727
SceS000004165
IDA
AthNAP57
HsaDKC1
TAS
MmuMGI:1861727
GO:0005732 small nucleolar ribonucleoprotein
complex		 C
ISS
SpoSPAC29A4.04c
GO:0005829 cytosol C
IDA
AthNAP57
SpoSPAC29A4.04c
GO:0030686 90S preribosome C
IDA
SceS000004165
GO:0031429 box H/ACA snoRNP complex C
IPI
SceS000004165
GO:0003720 telomerase activity F
IDA
HsaDKC1
GO:0003723 RNA binding F
TAS
MmuMGI:1861727
GO:0004730 pseudouridylate synthase activity F
IMP
SceS000004165
ISS
SceS000004165
SpoSPAC29A4.04c
TAS
MmuMGI:1861727
GO:0005515 protein binding F
IPI
HsaDKC1
GO:0009982 pseudouridine synthase activity F
IDA
SceS000004165
ISS
AthNAP57
TAS
AthNAP57
GO:0030519 snoRNP binding F
ISS
MmuMGI:1861727
GO:0000003 reproduction P
IMP
CelWBGene00010478
GO:0000154 rRNA modification P
ISA
MmuMGI:1861727
ISS
SpoSPAC29A4.04c
TAS
MmuMGI:1861727
GO:0000495 box H/ACA snoRNA 3'-end processing P
IMP
SceS000004165
GO:0002119 nematode larval development P
IMP
CelWBGene00010478
GO:0006364 rRNA processing P
IMP
SceS000004165
ISS
SpoSPAC29A4.04c
GO:0006396 RNA processing P
TAS
MmuMGI:1861727
GO:0006399 tRNA metabolic process P
NAS
SpoSPAC29A4.04c
GO:0007004 telomere maintenance via telomerase P
TAS
HsaDKC1
GO:0008150 biological_process P
ND
PfaPF14_0174
GO:0008283 cell proliferation P
TAS
HsaDKC1
GO:0031118 rRNA pseudouridine synthesis P
IMP
SceS000004165
GO:0031120 snRNA pseudouridine synthesis P
IDA
SceS000004165
IMP
SceS000004165
GO:0040007 growth P
IMP
CelWBGene00010478
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00010478

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1612

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga71 ENSANGP00000017710
Ashbya gossypii (Ago) ago180 AAL007C
Arabidopsis thaliana (Ath) ath17112 At3g57150.1
Caenorhabditis elegans (Cel) cel11593 K01G5.5
(CE16195;
WBGene00010478)
Candida glabrata (Cgl) cgl2221 CAGL0H03685g
Cryptococcus neoformans (Cne) cne589 163.m06243
Dictyostelium discoideum (Ddi) ddi4665 DDB0204297
Debaryomyces hansenii (Dha) dha6253 DEHA0G12430g
Drosophila melanogaster (Dme) dme6971 CG3333-PA
(FBgn0023184)
Danio rerio (Dre) dre13176 ENSDARP00000007628
(dkc1)		 Q7ZUT3
Encephalitozoon cuniculi (Ecu) ecu1204 19173642
Takifugu rubripes (Fru) fru14910 SINFRUP00000140014
Gallus gallus (Gga) gga16741 ENSGALP00000008091
(DKC1)		 Q5ZJH9
Gallus gallus (Gga) gga16742 ENSGALP00000008092
Homo sapiens (Hsa) hsa33669 ENSP00000253127
Kluyveromyces lactis (Kla) kla2272 KLLA0D04796g
Mus musculus (Mmu) mmu29193 ENSMUSP00000033776
(MGI:1861727)		 Q3TI79
Neurospora crassa (Ncr) ncr1250 NCU01290.2
Oryza sativa (Osa) osa19225 3473.m00148
Oryza sativa (Osa) osa33 385.m00224
Oryza sativa (Osa) osa54330 6075.m00086
Plasmodium falciparum (Pfa) pfa1537 PF14_0174
Rattus norvegicus (Rno) rno30210 ENSRNOP00000029509
Saccharomyces cerevisiae (Sce) sce4275 YLR175W
(S000004165)
Schizosaccharomyces pombe (Spo) spo3015 SPAC29A4.04c O14007
Yarrowia lipolytica (Yli) yli4419 YALI0E13486g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF14_0174
GO:0005730 nucleolus C
IC
MmuMGI:1861727
SceS000004165
IDA
AthAt3g57150
TAS
MmuMGI:1861727
GO:0005732 small nucleolar ribonucleoprotein
complex		 C
ISS
SpoSPAC29A4.04c
GO:0005829 cytosol C
IDA
AthAt3g57150
SpoSPAC29A4.04c
GO:0030686 90S preribosome C
IDA
SceS000004165
GO:0031429 box H/ACA snoRNP complex C
IPI
SceS000004165
GO:0003723 RNA binding F
TAS
MmuMGI:1861727
GO:0004730 pseudouridylate synthase activity F
IMP
SceS000004165
ISS
SceS000004165
SpoSPAC29A4.04c
TAS
MmuMGI:1861727
GO:0009982 pseudouridine synthase activity F
IDA
SceS000004165
ISS
AthAt3g57150
TAS
AthAt3g57150
GO:0030519 snoRNP binding F
ISS
MmuMGI:1861727
GO:0000003 reproduction P
IMP
CelWBGene00010478
GO:0000154 rRNA modification P
ISA
MmuMGI:1861727
ISS
SpoSPAC29A4.04c
TAS
MmuMGI:1861727
GO:0000495 box H/ACA snoRNA 3'-end processing P
IMP
SceS000004165
GO:0002119 nematode larval development P
IMP
CelWBGene00010478
GO:0006364 rRNA processing P
IMP
SceS000004165
ISS
SpoSPAC29A4.04c
GO:0006396 RNA processing P
TAS
MmuMGI:1861727
GO:0006399 tRNA metabolic process P
NAS
SpoSPAC29A4.04c
GO:0008150 biological_process P
ND
PfaPF14_0174
GO:0031118 rRNA pseudouridine synthesis P
IMP
SceS000004165
GO:0031120 snRNA pseudouridine synthesis P
IDA
SceS000004165
IMP
SceS000004165
GO:0040007 growth P
IMP
CelWBGene00010478
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00010478

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC29A4.04c
(O14007)		 YLR175W
(S000004165)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
IC
SceS000004165
GO:0005732 small nucleolar ribonucleoprotein
complex		 C
ISS
SpoSPAC29A4.04c
GO:0005829 cytosol C
IDA
SpoSPAC29A4.04c
GO:0030686 90S preribosome C
IDA
SceS000004165
GO:0031429 box H/ACA snoRNP complex C
IPI
SceS000004165
GO:0004730 pseudouridylate synthase activity F
IMP
SceS000004165
ISS
SceS000004165
SpoSPAC29A4.04c
GO:0009982 pseudouridine synthase activity F
IDA
SceS000004165
GO:0000154 rRNA modification P
ISS
SpoSPAC29A4.04c
GO:0000495 box H/ACA snoRNA 3'-end processing P
IMP
SceS000004165
GO:0006364 rRNA processing P
IMP
SceS000004165
ISS
SpoSPAC29A4.04c
GO:0006399 tRNA metabolic process P
NAS
SpoSPAC29A4.04c
GO:0031118 rRNA pseudouridine synthesis P
IMP
SceS000004165
GO:0031120 snRNA pseudouridine synthesis P
IDA
SceS000004165
IMP
SceS000004165

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GO info in one table:

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