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Search term: YLR176C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RFX1
SGD link S000004166
Alternative ID YLR176C
Description Major transcriptional repressor of DNA-damage-regulated genes, recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins
Synonyms YLR176C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3712 -CDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING RFX family transcription factor

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE17763
(WBGene00000914)		 GI:17532719
Caenorhabditis elegans (Cel) CE28019 GI:17532721
Drosophila melanogaster (Dme) 7299332 GI:7299332
Homo sapiens (Hsa) Hs4506495 GI:4506495 P48380
Homo sapiens (Hsa) Hs4557843
(RFX5)		 GI:4557843 P48382
Homo sapiens (Hsa) Hs19743877 GI:19743877
Homo sapiens (Hsa) Hs20533412_3 GI:20533412
Homo sapiens (Hsa) Hs19743881
(RFX2)		 GI:19743881 Q75MR3
Homo sapiens (Hsa) Hs20551991 GI:20551991
Homo sapiens (Hsa) Hs15011898 GI:15011898 Q8NDF9
Homo sapiens (Hsa) Hs19743879 GI:19743879 Q75MR3
Homo sapiens (Hsa) Hs19743884
(RFX3)		 GI:19743884 P48380
Homo sapiens (Hsa) Hs19743886 GI:19743886 Q8NDF9
Saccharomyces cerevisiae (Sce) YLR176c
(S000004166)		 GI:6323205 P48743
Schizosaccharomyces pombe (Spo) SPAC3G9.14 GI:19114998 P48383


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC3G9.14
GO:0005634 nucleus C
IDA
SceS000004166
SpoSPAC3G9.14
ISS
SpoSPAC3G9.14
GO:0005737 cytoplasm C
IDA
SceS000004166
ISS
SpoSPAC3G9.14
GO:0003677 DNA binding F
TAS
SpoSPAC3G9.14
GO:0003700 transcription factor activity F
NAS
HsaRFX5
GO:0005515 protein binding F
IPI
HsaRFX5
GO:0016563 transcription activator activity F
IMP
SceS000004166
GO:0016566 specific transcriptional repressor
activity		 F
IDA
SceS000004166
IGI
SceS000004166
IMP
SceS000004166
ISS
SpoSPAC3G9.14
GO:0043565 sequence-specific DNA binding F
IDA
SceS000004166
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
SceS000004166
IGI
SceS000004166
IMP
SceS000004166
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
CelWBGene00000914
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPAC3G9.14
GO:0016481 negative regulation of transcription P
ISS
SpoSPAC3G9.14
GO:0031536 positive regulation of exit from
mitosis		 P
IMP
SpoSPAC3G9.14
GO:0032569 gene-specific transcription from RNA polymerase II
promoter		 P
IC
SpoSPAC3G9.14
GO:0043053 dauer entry P
IMP
CelWBGene00000914
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000004166

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117872

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) RFX1
(S000004166)		 GI:6323205 P48743
Kluyveromyces lactis (Kla) KLLA0D04862g GI:50306605
Eremothecium gossypii (Ego) AGOS_AAL010W GI:45184814


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004166
GO:0005737 cytoplasm C
IDA
SceS000004166
GO:0016563 transcription activator activity F
IMP
SceS000004166
GO:0016566 specific transcriptional repressor
activity		 F
IDA
SceS000004166
IGI
SceS000004166
IMP
SceS000004166
GO:0043565 sequence-specific DNA binding F
IDA
SceS000004166
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
SceS000004166
IGI
SceS000004166
IMP
SceS000004166
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000004166

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_839

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6457 ENSANGP00000002747
Anopheles gambiae (Aga) aga6458 ENSANGP00000027850
Ashbya gossypii (Ago) ago177 AAL010W
Caenorhabditis elegans (Cel) cel8019 F33H1.1a
(CE17763;
WBGene00000914)
Caenorhabditis elegans (Cel) cel8020 F33H1.1b
(CE28019)
Candida glabrata (Cgl) cgl417 CAGL0B04895g
Candida glabrata (Cgl) cgl2224 CAGL0H03751g
Debaryomyces hansenii (Dha) dha6225 DEHA0G11814g
Drosophila melanogaster (Dme) dme16624 CG15772-PA
(FBgn0029799)
Drosophila melanogaster (Dme) dme11890 CG6312-PA
(FBgn0020379)
Danio rerio (Dre) dre1192 ENSDARP00000010260
(LOC555183)
Danio rerio (Dre) dre22642 ENSDARP00000012441
(LOC570981)
Danio rerio (Dre) dre22643 ENSDARP00000015449
Danio rerio (Dre) dre22641 ENSDARP00000039332
(zgc:91808)		 Q5EAP5
Takifugu rubripes (Fru) fru5795 SINFRUP00000136651
Takifugu rubripes (Fru) fru25535 SINFRUP00000137506
Takifugu rubripes (Fru) fru11419 SINFRUP00000155845
Takifugu rubripes (Fru) fru21154 SINFRUP00000156615
Takifugu rubripes (Fru) fru11421 SINFRUP00000165928
Takifugu rubripes (Fru) fru21153 SINFRUP00000171051
Takifugu rubripes (Fru) fru21155 SINFRUP00000172409
Takifugu rubripes (Fru) fru11420 SINFRUP00000173549
Takifugu rubripes (Fru) fru5794 SINFRUP00000175333
Takifugu rubripes (Fru) fru11422 SINFRUP00000175492
Gallus gallus (Gga) gga14095 ENSGALP00000002721
(RFX2)
Gallus gallus (Gga) gga14096 ENSGALP00000002722
Gallus gallus (Gga) gga14097 ENSGALP00000002723
Gallus gallus (Gga) gga28099 ENSGALP00000016528
Gallus gallus (Gga) gga28098 ENSGALP00000016529
Homo sapiens (Hsa) hsa15771 ENSP00000254325
(RFX1)		 P22670
Homo sapiens (Hsa) hsa30968 ENSP00000265775
Homo sapiens (Hsa) hsa8109 ENSP00000266774
(RFX4)		 Q33E94-4
Homo sapiens (Hsa) hsa30969 ENSP00000303847
(RFX3)		 P48380-2
Homo sapiens (Hsa) hsa15430 ENSP00000306335
(RFX2)		 P48378-1
Homo sapiens (Hsa) hsa30970 ENSP00000351574
(RFX3)		 P48380-2
Homo sapiens (Hsa) hsa15431 ENSP00000352076
(RFX2)		 P48378-2
Kluyveromyces lactis (Kla) kla2275 KLLA0D04862g
Mus musculus (Mmu) mmu11962 ENSMUSP00000002444
(MGI:106583)		 P48379-1
Mus musculus (Mmu) mmu26304 ENSMUSP00000005600
(MGI:105982)		 Q3V383
Mus musculus (Mmu) mmu13555 ENSMUSP00000038760
(MGI:106582)		 P48381-1
Neurospora crassa (Ncr) ncr6517 NCU06701.2
Rattus norvegicus (Rno) rno14777 ENSRNOP00000008104
(RGD:1306574)
Rattus norvegicus (Rno) rno3937 ENSRNOP00000019515
(RGD:1307779)
Saccharomyces cerevisiae (Sce) sce4276 YLR176C
(S000004166)
Schizosaccharomyces pombe (Spo) spo4074 SPAC3G9.14 P48383
Yarrowia lipolytica (Yli) yli4424 YALI0E13596g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC3G9.14
GO:0005634 nucleus C
IDA
SceS000004166
SpoSPAC3G9.14
ISS
SpoSPAC3G9.14
NAS
DmeFBgn0020379
GO:0005737 cytoplasm C
IDA
SceS000004166
ISS
SpoSPAC3G9.14
GO:0003677 DNA binding F
IDA
MmuMGI:105982
TAS
SpoSPAC3G9.14
GO:0003702 RNA polymerase II transcription factor
activity		 F
NAS
DmeFBgn0020379
GO:0005515 protein binding F
IPI
MmuMGI:106582
GO:0010843 promoter binding F
IDA
MmuMGI:106582
GO:0016563 transcription activator activity F
IMP
SceS000004166
GO:0016566 specific transcriptional repressor
activity		 F
IDA
SceS000004166
IGI
SceS000004166
IMP
SceS000004166
ISS
SpoSPAC3G9.14
GO:0030528 transcription regulator activity F
IMP
MmuMGI:106582
GO:0043565 sequence-specific DNA binding F
IDA
SceS000004166
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
SceS000004166
IGI
SceS000004166
IMP
SceS000004166
GO:0006355 regulation of transcription, DNA-dependent P
IMP
MmuMGI:106582
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
IMP
CelWBGene00000914
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPAC3G9.14
GO:0007368 determination of left/right symmetry P
IMP
MmuMGI:106582
GO:0007399 nervous system development P
IMP
DmeFBgn0020379
GO:0016481 negative regulation of transcription P
ISS
SpoSPAC3G9.14
GO:0031018 endocrine pancreas development P
IMP
MmuMGI:106582
GO:0031536 positive regulation of exit from
mitosis		 P
IMP
SpoSPAC3G9.14
GO:0032569 gene-specific transcription from RNA polymerase II
promoter		 P
IC
SpoSPAC3G9.14
GO:0043053 dauer entry P
IMP
CelWBGene00000914
GO:0045449 regulation of transcription P
TAS
DmeFBgn0020379
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000004166
GO:0048813 dendrite morphogenesis P
TAS
DmeFBgn0020379
GO:0050796 regulation of insulin secretion P
IMP
MmuMGI:106582
GO:0060285 ciliary cell motility P
IMP
MmuMGI:106582
GO:0060287 cilium movement involved in determination of
left/right asymmetry		 P
IMP
MmuMGI:106582

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC3G9.14
(P48383)		 YLR176C
(S000004166)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IC
SpoSPAC3G9.14
GO:0005634 nucleus C
IDA
SceS000004166
SpoSPAC3G9.14
ISS
SpoSPAC3G9.14
GO:0005737 cytoplasm C
IDA
SceS000004166
ISS
SpoSPAC3G9.14
GO:0003677 DNA binding F
TAS
SpoSPAC3G9.14
GO:0016563 transcription activator activity F
IMP
SceS000004166
GO:0016566 specific transcriptional repressor
activity		 F
IDA
SceS000004166
IGI
SceS000004166
IMP
SceS000004166
ISS
SpoSPAC3G9.14
GO:0043565 sequence-specific DNA binding F
IDA
SceS000004166
GO:0000122 negative regulation of transcription from RNA
polymerase II promoter		 P
IDA
SceS000004166
IGI
SceS000004166
IMP
SceS000004166
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPAC3G9.14
GO:0016481 negative regulation of transcription P
ISS
SpoSPAC3G9.14
GO:0031536 positive regulation of exit from
mitosis		 P
IMP
SpoSPAC3G9.14
GO:0032569 gene-specific transcription from RNA polymerase II
promoter		 P
IC
SpoSPAC3G9.14
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
SceS000004166

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GO info in one table:

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