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Search term: YLR193C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name UPS1
SGD link S000004183
Alternative ID YLR193C
Description Mitochondrial intermembrane space protein that regulates mitochondrial cardiolipin levels, null has defects in Mgm1p processing, integrity of mitochondrial inner membrane complexes, and mitochondrial morphology; ortholog of human PRELI
Synonyms YLR193C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3337 -CDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Protein similar to predicted member of the intramitochondrial sorting protein family

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE02936
(WBGene00007144)
GI:17531303 Q17476
Drosophila melanogaster (Dme) 7303894 GI:20129823
Homo sapiens (Hsa) Hs17477769 GI:17477769
Homo sapiens (Hsa) Hs20473176 GI:20473176
Homo sapiens (Hsa) Hs22044072 GI:22044072
Homo sapiens (Hsa) Hs7019509
(PRELID1)
GI:7019509 Q9Y255
Saccharomyces cerevisiae (Sce) YLR193c
(S000004183)
GI:6323222 Q05776
Schizosaccharomyces pombe (Spo) SPAP8A3.10 GI:19115861 Q9UT07


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaPRELID1
SpoSPAP8A3.10
GO:0005739 mitochondrion C
IDA
HsaPRELID1
SceS000004183
SpoSPAP8A3.10
ISS
HsaPRELID1
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000004183
ISS
SpoSPAP8A3.10
GO:0005829 cytosol C
IDA
SpoSPAP8A3.10
GO:0031314 extrinsic to mitochondrial inner
membrane
C
IDA
SceS000004183
ISS
SpoSPAP8A3.10
GO:0003674 molecular_function F
ND
SceS000004183
SpoSPAP8A3.10
GO:0000003 reproduction P
IMP
CelWBGene00007144
GO:0006627 protein processing involved in protein targeting
to mitochondrion
P
ISS
SpoSPAP8A3.10
GO:0006955 immune response P
TAS
HsaPRELID1
GO:0007275 multicellular organismal development P
TAS
HsaPRELID1
GO:0032048 cardiolipin metabolic process P
IMP
SceS000004183

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40859

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PRELID1 GI:7019509 Q9Y255
Pan troglodytes (Ptr) PRELID1 GI:114577641
Canis familiaris (Cfa) PRELID1 GI:73953256
Mus musculus (Mmu) Prelid1
(MGI:1913744)
GI:46518501 Q8R107
Rattus norvegicus (Rno) Prelid1 GI:57526905
Gallus gallus (Gga) PRELID1 GI:45384458
Drosophila melanogaster (Dme) prel
(FBgn0033413)
GI:22024092
Anopheles gambiae (Aga) AgaP_AGAP010959 GI:158287846
Caenorhabditis elegans (Cel) B0334.4
(CE02936;
WBGene00007144)
GI:17531303 Q17476
Schizosaccharomyces pombe (Spo) SPAP8A3.10 GI:19115861 Q9UT07
Saccharomyces cerevisiae (Sce) UPS1
(S000004183)
GI:6323222 Q05776
Kluyveromyces lactis (Kla) KLLA0E19679g GI:50309651
Eremothecium gossypii (Ego) AGOS_AAR075C GI:45184898


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaPRELID1
SpoSPAP8A3.10
GO:0005739 mitochondrion C
IDA
DmeFBgn0033413
HsaPRELID1
MmuMGI:1913744
SceS000004183
SpoSPAP8A3.10
ISS
HsaPRELID1
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000004183
ISS
SpoSPAP8A3.10
GO:0005829 cytosol C
IDA
SpoSPAP8A3.10
GO:0030061 mitochondrial crista C
IDA
DmeFBgn0033413
GO:0031314 extrinsic to mitochondrial inner
membrane
C
IDA
SceS000004183
ISS
SpoSPAP8A3.10
GO:0003674 molecular_function F
ND
DmeFBgn0033413
SceS000004183
SpoSPAP8A3.10
GO:0000003 reproduction P
IMP
CelWBGene00007144
GO:0006627 protein processing involved in protein targeting
to mitochondrion
P
ISS
SpoSPAP8A3.10
GO:0006955 immune response P
TAS
HsaPRELID1
GO:0007275 multicellular organismal development P
TAS
HsaPRELID1
GO:0032048 cardiolipin metabolic process P
IMP
SceS000004183
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0033413
GO:0070584 mitochondrion morphogenesis P
IMP
DmeFBgn0033413

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4777

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga7963 ENSANGP00000027384
Ashbya gossypii (Ago) ago261 AAR075C
Caenorhabditis elegans (Cel) cel356 B0334.4
(CE02936;
WBGene00007144)
Candida glabrata (Cgl) cgl172 CAGL0A04103g
Debaryomyces hansenii (Dha) dha6049 DEHA0G07799g
Drosophila melanogaster (Dme) dme4077 CG8806-PA
(FBgn0033413)
Danio rerio (Dre) dre5041 ENSDARP00000007653
Takifugu rubripes (Fru) fru10645 SINFRUP00000141833
Takifugu rubripes (Fru) fru21073 SINFRUP00000153464
Gallus gallus (Gga) gga5795 ENSGALP00000004724
(PRELID1)
Q90673
Homo sapiens (Hsa) hsa17887 ENSP00000238849
Homo sapiens (Hsa) hsa26224 ENSP00000302114
(PRELID1)
Q9Y255
Kluyveromyces lactis (Kla) kla3836 KLLA0E19679g
Mus musculus (Mmu) mmu7011 ENSMUSP00000021942
(MGI:1913744)
Q8R107
Neurospora crassa (Ncr) ncr6535 NCU06719.2
Rattus norvegicus (Rno) rno13021 ENSRNOP00000022134
(RGD:1308082)
Q5M829
Saccharomyces cerevisiae (Sce) sce4293 YLR193C
(S000004183)
Schizosaccharomyces pombe (Spo) spo4282 SPAP8A3.10 Q9UT07
Yarrowia lipolytica (Yli) yli2520 YALI0C20141g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAP8A3.10
GO:0005739 mitochondrion C
IDA
DmeFBgn0033413
MmuMGI:1913744
SceS000004183
SpoSPAP8A3.10
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000004183
ISS
SpoSPAP8A3.10
GO:0005829 cytosol C
IDA
SpoSPAP8A3.10
GO:0030061 mitochondrial crista C
IDA
DmeFBgn0033413
GO:0031314 extrinsic to mitochondrial inner
membrane
C
IDA
SceS000004183
ISS
SpoSPAP8A3.10
GO:0003674 molecular_function F
ND
DmeFBgn0033413
SceS000004183
SpoSPAP8A3.10
GO:0000003 reproduction P
IMP
CelWBGene00007144
GO:0006627 protein processing involved in protein targeting
to mitochondrion
P
ISS
SpoSPAP8A3.10
GO:0032048 cardiolipin metabolic process P
IMP
SceS000004183
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0033413
GO:0070584 mitochondrion morphogenesis P
IMP
DmeFBgn0033413

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAP8A3.10
(Q9UT07)
YLR193C
(S000004183)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAP8A3.10
GO:0005739 mitochondrion C
IDA
SceS000004183
SpoSPAP8A3.10
GO:0005758 mitochondrial intermembrane space C
IDA
SceS000004183
ISS
SpoSPAP8A3.10
GO:0005829 cytosol C
IDA
SpoSPAP8A3.10
GO:0031314 extrinsic to mitochondrial inner
membrane
C
IDA
SceS000004183
ISS
SpoSPAP8A3.10
GO:0003674 molecular_function F
ND
SceS000004183
SpoSPAP8A3.10
GO:0006627 protein processing involved in protein targeting
to mitochondrion
P
ISS
SpoSPAP8A3.10
GO:0032048 cardiolipin metabolic process P
IMP
SceS000004183

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GO info in one table:

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