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Search term: YLR209C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PNP1
SGD link S000004199
Alternative ID YLR209C
Description Purine nucleoside phosphorylase, specifically metabolizes inosine and guanosine nucleosides; involved in the nicotinamide riboside salvage pathway
Synonyms YLR209C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3984 -CDHYP-

KOGs classification KOGs description
METABOLISM Purine nucleoside phosphorylase

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE17994
(WBGene00019298)		 GI:17541190 O61217
Drosophila melanogaster (Dme) 7291629 GI:7291629
Drosophila melanogaster (Dme) 7292245 GI:7292245 Q9W004
Homo sapiens (Hsa) Hs4557801 GI:4557801
Homo sapiens (Hsa) Hs18550128 GI:18550128
Saccharomyces cerevisiae (Sce) YLR209c
(S000004199)		 GI:6323238 Q05788
Schizosaccharomyces pombe (Spo) SPAC1805.16c GI:19114839 Q9UTG1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
IC
SceS000004199
GO:0005634 nucleus C
IDA
SpoSPAC1805.16c
GO:0005829 cytosol C
IDA
SpoSPAC1805.16c
GO:0004731 purine-nucleoside phosphorylase
activity		 F
IDA
SceS000004199
IMP
SceS000004199
ISS
SceS000004199
SpoSPAC1805.16c
GO:0047724 inosine nucleosidase activity F
IDA
SceS000004199
GO:0070635 nicotinamide riboside hydrolase
activity		 F
IDA
SceS000004199
GO:0006148 inosine catabolic process P
IMP
SceS000004199
GO:0006152 purine nucleoside catabolic process P
ISS
SpoSPAC1805.16c
GO:0019358 nicotinate nucleotide salvage P
IGI
SceS000004199
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage
pathway		 P
IGI
SceS000004199
ISS
SpoSPAC1805.16c
GO:0040011 locomotion P
IMP
CelWBGene00019298
GO:0046115 guanosine catabolic process P
IMP
SceS000004199

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
227

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NP GI:157168362
Pan troglodytes (Ptr) NP GI:114651774
Canis familiaris (Cfa) NP GI:73977271
Mus musculus (Mmu) Pnp2
(MGI:3712328)		 GI:94397057 Q9D8C9
Mus musculus (Mmu) Pnp1
(MGI:97365)		 GI:7305395 P23492
Rattus norvegicus (Rno) Np GI:34869683
Drosophila melanogaster (Dme) CG16758
(FBgn0035348)		 GI:24656093
Anopheles gambiae (Aga) AgaP_AGAP005945 GI:158295053
Anopheles gambiae (Aga) AgaP_AGAP005944 GI:158295049
Caenorhabditis elegans (Cel) phosphorylase GI:17541190 O61217
Schizosaccharomyces pombe (Spo) SPAC1805.16c GI:19114839 Q9UTG1
Saccharomyces cerevisiae (Sce) PNP1
(S000004199)		 GI:6323238 Q05788
Kluyveromyces lactis (Kla) KLLA0C16621g GI:50305965
Eremothecium gossypii (Ego) AGOS_ACR198W GI:45185884


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:3712328
GO:0005576 extracellular region C
ISO
MmuMGI:97365
GO:0005622 intracellular C
IC
SceS000004199
GO:0005634 nucleus C
IDA
SpoSPAC1805.16c
ISO
MmuMGI:97365
GO:0005737 cytoplasm C
ISO
MmuMGI:97365
GO:0005829 cytosol C
IDA
MmuMGI:97365
SpoSPAC1805.16c
GO:0003674 molecular_function F
ND
MmuMGI:3712328
GO:0004731 purine-nucleoside phosphorylase
activity		 F
IDA
MmuMGI:97365
SceS000004199
IMP
MmuMGI:97365
SceS000004199
ISO
MmuMGI:97365
ISS
DmeFBgn0035348
SceS000004199
SpoSPAC1805.16c
GO:0047724 inosine nucleosidase activity F
IDA
SceS000004199
GO:0070635 nicotinamide riboside hydrolase
activity		 F
IDA
SceS000004199
GO:0001916 positive regulation of T cell mediated
cytotoxicity		 P
IMP
MmuMGI:97365
GO:0006148 inosine catabolic process P
IMP
MmuMGI:97365
SceS000004199
ISO
MmuMGI:97365
GO:0006149 deoxyinosine catabolic process P
IMP
MmuMGI:97365
GO:0006152 purine nucleoside catabolic process P
ISS
SpoSPAC1805.16c
GO:0006161 deoxyguanosine catabolic process P
IMP
MmuMGI:97365
GO:0006183 GTP biosynthetic process P
IMP
MmuMGI:97365
GO:0008150 biological_process P
ND
MmuMGI:3712328
GO:0010332 response to gamma radiation P
IMP
MmuMGI:97365
GO:0019358 nicotinate nucleotide salvage P
IGI
SceS000004199
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage
pathway		 P
IGI
SceS000004199
ISS
SpoSPAC1805.16c
GO:0034418 urate biosynthetic process P
IMP
MmuMGI:97365
ISO
MmuMGI:97365
GO:0042102 positive regulation of T cell proliferation P
IMP
MmuMGI:97365
ISO
MmuMGI:97365
GO:0042278 purine nucleoside metabolic process P
IC
MmuMGI:97365
IDA
MmuMGI:97365
IMP
MmuMGI:97365
ISO
MmuMGI:97365
GO:0043066 negative regulation of apoptosis P
IMP
MmuMGI:97365
GO:0045579 positive regulation of B cell differentiation P
IMP
MmuMGI:97365
GO:0045739 positive regulation of DNA repair P
IMP
MmuMGI:97365
GO:0046070 dGTP metabolic process P
IMP
MmuMGI:97365
GO:0046115 guanosine catabolic process P
IMP
MmuMGI:97365
SceS000004199
GO:0046638 positive regulation of alpha-beta T cell
differentiation		 P
IMP
MmuMGI:97365
ISO
MmuMGI:97365

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1945

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1389 ENSANGP00000010803
Anopheles gambiae (Aga) aga1390 ENSANGP00000025345
Ashbya gossypii (Ago) ago1245 ACR198W
Caenorhabditis elegans (Cel) cel11650 K02D7.1
(CE17994;
WBGene00019298)
Candida glabrata (Cgl) cgl3376 CAGL0J08800g
Debaryomyces hansenii (Dha) dha6101 DEHA0G09031g
Drosophila melanogaster (Dme) dme7606 CG16758-PB
(FBgn0035348)
Drosophila melanogaster (Dme) dme7607 CG16758-PD
(FBgn0035348)
Drosophila melanogaster (Dme) dme7608 CG16758-PE
(FBgn0035348)
Drosophila melanogaster (Dme) dme7609 CG16758-PF
(FBgn0035348)
Danio rerio (Dre) dre5539 ENSDARP00000024352
Danio rerio (Dre) dre22208 ENSDARP00000026961
Danio rerio (Dre) dre2711 ENSDARP00000032177
(zgc:86889)		 Q6IQ95
Danio rerio (Dre) dre9230 ENSDARP00000039603
Danio rerio (Dre) dre9221 ENSDARP00000050469
Escherichia coli (Eco) eco2328 16130333
Takifugu rubripes (Fru) fru22241 SINFRUP00000157233
Takifugu rubripes (Fru) fru2450 SINFRUP00000159668
Gallus gallus (Gga) gga4460 ENSGALP00000003703
Homo sapiens (Hsa) hsa9149 ENSP00000354532
(PNP)		 Q8N7G1
Kluyveromyces lactis (Kla) kla1942 KLLA0C16621g
Mus musculus (Mmu) mmu8070 ENSMUSP00000022422
Mus musculus (Mmu) mmu8069 ENSMUSP00000043926
(MGI:97365)		 Q543K9
Mus musculus (Mmu) mmu8068 ENSMUSP00000076235
(MGI:97365)
Rattus norvegicus (Rno) rno11234 ENSRNOP00000013582
(RGD:1597189)
Saccharomyces cerevisiae (Sce) sce4309 YLR209C
(S000004199)
Schizosaccharomyces pombe (Spo) spo1566 SPAC1805.16c Q9UTG1
Yarrowia lipolytica (Yli) yli6578 YALI0F30129g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005576 extracellular region C
ISO
MmuMGI:97365
GO:0005622 intracellular C
IC
SceS000004199
GO:0005634 nucleus C
IDA
SpoSPAC1805.16c
ISO
MmuMGI:97365
GO:0005737 cytoplasm C
ISO
MmuMGI:97365
GO:0005829 cytosol C
IDA
MmuMGI:97365
SpoSPAC1805.16c
GO:0004731 purine-nucleoside phosphorylase
activity		 F
IDA
MmuMGI:97365
SceS000004199
IMP
MmuMGI:97365
SceS000004199
ISO
MmuMGI:97365
ISS
DmeFBgn0035348
SceS000004199
SpoSPAC1805.16c
GO:0047724 inosine nucleosidase activity F
IDA
SceS000004199
GO:0070635 nicotinamide riboside hydrolase
activity		 F
IDA
SceS000004199
GO:0001916 positive regulation of T cell mediated
cytotoxicity		 P
IMP
MmuMGI:97365
GO:0006148 inosine catabolic process P
IMP
MmuMGI:97365
SceS000004199
ISO
MmuMGI:97365
GO:0006149 deoxyinosine catabolic process P
IMP
MmuMGI:97365
GO:0006152 purine nucleoside catabolic process P
ISS
SpoSPAC1805.16c
GO:0006161 deoxyguanosine catabolic process P
IMP
MmuMGI:97365
GO:0006183 GTP biosynthetic process P
IMP
MmuMGI:97365
GO:0010332 response to gamma radiation P
IMP
MmuMGI:97365
GO:0019358 nicotinate nucleotide salvage P
IGI
SceS000004199
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage
pathway		 P
IGI
SceS000004199
ISS
SpoSPAC1805.16c
GO:0034418 urate biosynthetic process P
IMP
MmuMGI:97365
ISO
MmuMGI:97365
GO:0040011 locomotion P
IMP
CelWBGene00019298
GO:0042102 positive regulation of T cell proliferation P
IMP
MmuMGI:97365
ISO
MmuMGI:97365
GO:0042278 purine nucleoside metabolic process P
IC
MmuMGI:97365
IDA
MmuMGI:97365
IMP
MmuMGI:97365
ISO
MmuMGI:97365
GO:0043066 negative regulation of apoptosis P
IMP
MmuMGI:97365
GO:0045579 positive regulation of B cell differentiation P
IMP
MmuMGI:97365
GO:0045739 positive regulation of DNA repair P
IMP
MmuMGI:97365
GO:0046070 dGTP metabolic process P
IMP
MmuMGI:97365
GO:0046115 guanosine catabolic process P
IMP
MmuMGI:97365
SceS000004199
GO:0046638 positive regulation of alpha-beta T cell
differentiation		 P
IMP
MmuMGI:97365
ISO
MmuMGI:97365

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1805.16c
(Q9UTG1)		 YLR209C
(S000004199)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
IC
SceS000004199
GO:0005634 nucleus C
IDA
SpoSPAC1805.16c
GO:0005829 cytosol C
IDA
SpoSPAC1805.16c
GO:0004731 purine-nucleoside phosphorylase
activity		 F
IDA
SceS000004199
IMP
SceS000004199
ISS
SceS000004199
SpoSPAC1805.16c
GO:0047724 inosine nucleosidase activity F
IDA
SceS000004199
GO:0070635 nicotinamide riboside hydrolase
activity		 F
IDA
SceS000004199
GO:0006148 inosine catabolic process P
IMP
SceS000004199
GO:0006152 purine nucleoside catabolic process P
ISS
SpoSPAC1805.16c
GO:0019358 nicotinate nucleotide salvage P
IGI
SceS000004199
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage
pathway		 P
IGI
SceS000004199
ISS
SpoSPAC1805.16c
GO:0046115 guanosine catabolic process P
IMP
SceS000004199

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

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