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Search term: YLR216C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CPR6
SGD link S000004206
Alternative ID YLR216C
Description Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity
Synonyms YLR216C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0546 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING HSP90 co-chaperone CPR7/Cyclophilin

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g15790 GI:15226623
Caenorhabditis elegans (Cel) CE03745
(WBGene00000885)		 GI:17552784 Q09637
Caenorhabditis elegans (Cel) CE04286
(WBGene00000884)		 GI:17551284 P52016
Caenorhabditis elegans (Cel) CE27892 GI:17551282 P52016
Drosophila melanogaster (Dme) 7294905 GI:7294905 Q9VT21
Drosophila melanogaster (Dme) 7301671_1 GI:7301671 Q9VAW1
Homo sapiens (Hsa) Hs4758106_1 GI:4758106
Homo sapiens (Hsa) Hs4826932
(PPID)		 GI:4826932 Q08752
Homo sapiens (Hsa) Hs6631100
(NKTR)		 GI:6631100 P30414
Saccharomyces cerevisiae (Sce) YJR032w
(S000003793)		 GI:6322492 P47103
Saccharomyces cerevisiae (Sce) YLR216c
(S000004206)		 GI:6323246 P53691
Schizosaccharomyces pombe (Spo) SPAC1B3.03c GI:19115699 Q11004
Arabidopsis thaliana (Ath) At2g15790 GI:15226623
Caenorhabditis elegans (Cel) CE03745
(WBGene00000885)		 GI:17552784 Q09637
Caenorhabditis elegans (Cel) CE04286
(WBGene00000884)		 GI:17551284 P52016
Caenorhabditis elegans (Cel) CE27892 GI:17551282 P52016
Drosophila melanogaster (Dme) 7294905 GI:7294905 Q9VT21
Drosophila melanogaster (Dme) 7301671_1 GI:7301671 Q9VAW1
Homo sapiens (Hsa) Hs4758106_1 GI:4758106
Homo sapiens (Hsa) Hs4826932
(PPID)		 GI:4826932 Q08752
Homo sapiens (Hsa) Hs6631100
(NKTR)		 GI:6631100 P30414
Saccharomyces cerevisiae (Sce) YJR032w
(S000003793)		 GI:6322492 P47103
Saccharomyces cerevisiae (Sce) YLR216c
(S000004206)		 GI:6323246 P53691
Schizosaccharomyces pombe (Spo) SPAC1B3.03c GI:19115699 Q11004


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
IDA
CelWBGene00000885
GO:0005634 nucleus C
IDA
CelWBGene00000884
SpoSPAC1B3.03c
GO:0005737 cytoplasm C
IDA
AthAt2g15790
SceS000004206
GO:0005829 cytosol C
IDA
SpoSPAC1B3.03c
IPI
SceS000003793
GO:0043234 protein complex C
NAS
SpoSPAC1B3.03c
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity		 F
IDA
CelWBGene00000884
SceS000003793
S000004206
ISS
AthAt2g15790
CelWBGene00000885
GO:0005515 protein binding F
IPI
HsaPPID
GO:0016018 cyclosporin A binding F
TAS
HsaPPID
NKTR
GO:0031072 heat shock protein binding F
IPI
HsaPPID
GO:0051082 unfolded protein binding F
IDA
SceS000004206
S000003793
GO:0006457 protein folding P
IDA
SceS000004206
IPI
SceS000004206
ISS
CelWBGene00000884
RCA
SceS000004206
TAS
CelWBGene00000885
GO:0006950 response to stress P
IGI
SceS000003793
IMP
SceS000003793
GO:0007088 regulation of mitosis P
IMP
SpoSPAC1B3.03c
GO:0010050 vegetative phase change P
IMP
AthAt2g15790
GO:0010582 floral meristem determinacy P
IGI
AthAt2g15790
GO:0030198 extracellular matrix organization P
TAS
CelWBGene00000885
GO:0033554 cellular response to stress P
NAS
SpoSPAC1B3.03c
GO:0042026 protein refolding P
IDA
SceS000004206
S000003793
GO:0051130 positive regulation of cellular component
organization		 P
RCA
SceS000004206

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31283

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PPID GI:4826932 Q08752
Pan troglodytes (Ptr) PPID GI:114596625
Canis familiaris (Cfa) PPID GI:57096873
Mus musculus (Mmu) Ppid
(MGI:1914988)		 GI:13385854 Q3UB60
Rattus norvegicus (Rno) Ppid
(RGD:1303174)		 GI:51948528
Rattus norvegicus (Rno) RGD1560149 GI:62655561
Gallus gallus (Gga) PPID GI:118089782
Drosophila melanogaster (Dme) CG8336
(FBgn0036020)		 GI:21355237
Anopheles gambiae (Aga) AgaP_AGAP003265 GI:118777240
Schizosaccharomyces pombe (Spo) cyp5 GI:19115699
Saccharomyces cerevisiae (Sce) CPR6
(S000004206)		 GI:6323246 P53691
Kluyveromyces lactis (Kla) KLLA0F05093g GI:50310583
Eremothecium gossypii (Ego) AGOS_ADR087C GI:45187960
Magnaporthe grisea (Mgr) MGG_08104 GI:39945968
Neurospora crassa (Ncr) NCU03853.1 GI:32405118
Arabidopsis thaliana (Ath) SQN GI:18397936
Oryza sativa (Osa) Os06g0216800 GI:115467098
Oryza sativa (Osa) Os02g0761100 GI:115448829


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1914988
GO:0005737 cytoplasm C
IDA
AthSQN
SceS000004206
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity		 F
IDA
SceS000004206
ISS
AthSQN
MmuMGI:1914988
GO:0005515 protein binding F
IPI
HsaPPID
GO:0005528 FK506 binding F
TAS
MmuMGI:1914988
GO:0016018 cyclosporin A binding F
TAS
HsaPPID
GO:0031072 heat shock protein binding F
IPI
HsaPPID
GO:0051082 unfolded protein binding F
IDA
SceS000004206
GO:0006457 protein folding P
IDA
SceS000004206
IPI
SceS000004206
RCA
SceS000004206
GO:0008152 metabolic process P
ISS
MmuMGI:1914988
GO:0010050 vegetative phase change P
IMP
AthSQN
GO:0010582 floral meristem determinacy P
IGI
AthSQN
GO:0042026 protein refolding P
IDA
SceS000004206
GO:0051130 positive regulation of cellular component
organization		 P
RCA
SceS000004206

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3968

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5585 ENSANGP00000013567
Ashbya gossypii (Ago) ago1828 ADR087C
Arabidopsis thaliana (Ath) ath8424 At2g15790.1
Candida glabrata (Cgl) cgl3383 CAGL0J08954g
Cryptococcus neoformans (Cne) cne1323 180.m00270
Dictyostelium discoideum (Ddi) ddi4841 DDB0185614
Debaryomyces hansenii (Dha) dha629 DEHA0A14058g
Drosophila melanogaster (Dme) dme8804 CG8336-PA
(FBgn0036020)
Drosophila melanogaster (Dme) dme8805 CG8336-PB
(FBgn0036020)
Drosophila melanogaster (Dme) dme8806 CG8336-PC
(FBgn0036020)
Takifugu rubripes (Fru) fru10307 SINFRUP00000127731
Gallus gallus (Gga) gga17234 ENSGALP00000015366
(PPID)
Homo sapiens (Hsa) hsa24798 ENSP00000303754
(PPID)		 Q08752
Kluyveromyces lactis (Kla) kla4311 KLLA0F05093g
Mus musculus (Mmu) mmu16787 ENSMUSP00000029382
(MGI:1914988)		 Q9CR16
Neurospora crassa (Ncr) ncr3742 NCU03853.2
Oryza sativa (Osa) osa7657 2525.m00097
Oryza sativa (Osa) osa20544 3441.m00151
Oryza sativa (Osa) osa23468 3772.m00149
Oryza sativa (Osa) osa29598 4331.m00189
Rattus norvegicus (Rno) rno16234 ENSRNOP00000035797
(RGD:1303174)		 Q6DGG0
Saccharomyces cerevisiae (Sce) sce4316 YLR216C
(S000004206)
Schizosaccharomyces pombe (Spo) spo2946 SPAC1B3.03c Q11004
Yarrowia lipolytica (Yli) yli2398 YALI0C16775g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1914988
GO:0005634 nucleus C
IDA
SpoSPAC1B3.03c
GO:0005737 cytoplasm C
IDA
AthAt2g15790
SceS000004206
GO:0005829 cytosol C
IDA
SpoSPAC1B3.03c
GO:0043234 protein complex C
NAS
SpoSPAC1B3.03c
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity		 F
IDA
SceS000004206
ISS
AthAt2g15790
MmuMGI:1914988
GO:0005528 FK506 binding F
TAS
MmuMGI:1914988
GO:0051082 unfolded protein binding F
IDA
SceS000004206
GO:0006457 protein folding P
IDA
SceS000004206
IPI
SceS000004206
RCA
SceS000004206
GO:0007088 regulation of mitosis P
IMP
SpoSPAC1B3.03c
GO:0008152 metabolic process P
ISS
MmuMGI:1914988
GO:0010050 vegetative phase change P
IMP
AthAt2g15790
GO:0010582 floral meristem determinacy P
IGI
AthAt2g15790
GO:0033554 cellular response to stress P
NAS
SpoSPAC1B3.03c
GO:0042026 protein refolding P
IDA
SceS000004206
GO:0051130 positive regulation of cellular component
organization		 P
RCA
SceS000004206

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1B3.03c
(Q11004)		 YLR216C
(S000004206)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1B3.03c
GO:0005737 cytoplasm C
IDA
SceS000004206
GO:0005829 cytosol C
IDA
SpoSPAC1B3.03c
GO:0043234 protein complex C
NAS
SpoSPAC1B3.03c
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity		 F
IDA
SceS000004206
GO:0051082 unfolded protein binding F
IDA
SceS000004206
GO:0006457 protein folding P
IDA
SceS000004206
IPI
SceS000004206
RCA
SceS000004206
GO:0007088 regulation of mitosis P
IMP
SpoSPAC1B3.03c
GO:0033554 cellular response to stress P
NAS
SpoSPAC1B3.03c
GO:0042026 protein refolding P
IDA
SceS000004206
GO:0051130 positive regulation of cellular component
organization		 P
RCA
SceS000004206

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GO info in one table:

s.khadayate@ucl.ac.uk