Bahler Lab

Search term: YLR259C

Gene summary:

Species Saccharomyces cerevisiae (Sce)

Primary name HSP60

SGD link S000004249

Alternative ID YLR259C

Description Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated

Synonyms YLR259C

Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)

KOG0356 ACDHYP-

KOGs classification KOGs description

CELLULAR PROCESSES AND SIGNALING Mitochondrial chaperonin, Cpn60/Hsp60p

GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005634 nucleus C
IDA
Ath At3g13470

GO:0005730 nucleolus C
IDA
Ath At3g13470

GO:0005739 mitochondrion C
IDA
Ath At3g13470
At3g13860
At2g28000
At2g33210
At3g23990
At5g56500
Cel WBGene00002025
Sce S000000248
S000004249
Spo SPAC12G12.04
ISS
Ath At2g33210
Spo SPAC12G12.04

GO:0005743 mitochondrial inner membrane C
IDA
Sce S000000248

GO:0005759 mitochondrial matrix C
IDA
Ath At3g23990

GO:0005829 cytosol C
IDA
Ath At3g23990

GO:0005886 plasma membrane C
IDA
Ath At2g33210
At1g55490
At3g13860
At3g23990

GO:0009507 chloroplast C
IDA
Ath At2g33210
At1g55490
At3g13470
At1g26230
At5g56500
At2g28000
ISS
Ath At2g28000
NAS
Ath At1g55490

GO:0009570 chloroplast stroma C
IDA
Ath At1g55490
At3g13470
At2g28000
At5g56500

GO:0009579 thylakoid C
IDA
Ath At2g28000

GO:0009941 chloroplast envelope C
IDA
Ath At1g55490
At3g13470
At2g28000

GO:0010319 stromule C
IDA
Ath At1g55490

GO:0016020 membrane C
IDA
Ath At1g55490
At2g28000
At5g56500

GO:0022626 cytosolic ribosome C
IDA
Ath At1g55490
At3g13470
At2g28000
At3g23990

GO:0031966 mitochondrial membrane C
RCA
Sce S000004249

GO:0042645 mitochondrial nucleoid C
IDA
Sce S000004249
ISS
Spo SPAC12G12.04

GO:0048046 apoplast C
IDA
Ath At1g55490
At2g28000

GO:0003688 DNA replication origin binding F
IDA
Sce S000004249

GO:0003697 single-stranded DNA binding F
IDA
Sce S000004249
ISS
Spo SPAC12G12.04

GO:0005507 copper ion binding F
IDA
Ath At2g33210
At3g23990

GO:0005515 protein binding F
IPI
Ath At1g55490

GO:0005524 ATP binding F
IDA
Ath At2g33210
At3g23990
ISS
Spo SPAC12G12.04

GO:0008134 transcription factor binding F
IPI
Cel WBGene00002025

GO:0016887 ATPase activity F
IDA
Sce S000004249

GO:0051082 unfolded protein binding F
IMP
Sce S000000248
S000004249
ISS
Cel WBGene00002025

GO:0051087 chaperone binding F
IPI
Sce S000004249

GO:0000003 reproduction P
IMP
Cel WBGene00002025

GO:0000302 response to reactive oxygen species P
IEP
Cel WBGene00002025

GO:0002119 nematode larval development P
IMP
Cel WBGene00002025

GO:0006082 organic acid metabolic process P
RCA
Sce S000004249

GO:0006457 protein folding P
ISS
Spo SPAC12G12.04
TAS
Ath At1g55490
At2g28000

GO:0006458 'de novo' protein folding P
IMP
Sce S000004249

GO:0006954 inflammatory response P
ISS
Ath At2g33210

GO:0007005 mitochondrion organization P
IMP
Cel WBGene00002025
TAS
Ath At3g23990

GO:0008219 cell death P
IMP
Ath At1g55490

GO:0009408 response to heat P
IEP
Ath At3g23990

GO:0009409 response to cold P
IEP
Ath At1g55490

GO:0009627 systemic acquired resistance P
IMP
Ath At1g55490

GO:0009658 chloroplast organization P
IMP
Ath At2g28000

GO:0009790 embryo development P
IMP
Ath At2g28000

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00002025

GO:0009793 embryo development ending in seed
dormancy P
NAS
Ath At5g18820

GO:0030150 protein import into mitochondrial
matrix P
ISS
Spo SPAC12G12.04

GO:0034514 mitochondrial unfolded protein
response P
IEP
Cel WBGene00002025

GO:0034553 mitochondrial respiratory chain complex II
assembly P
IMP
Sce S000000248
IPI
Sce S000000248

GO:0034605 cellular response to heat P
IEP
Spo SPAC12G12.04

GO:0042026 protein refolding P
IDA
Sce S000004249
IMP
Sce S000004249

GO:0045041 protein import into mitochondrial intermembrane
space P
IMP
Sce S000004249

GO:0046686 response to cadmium ion P
IEP
Ath At3g13860
At3g23990

GO:0050821 protein stabilization P
IMP
Sce S000004249

GO:0051085 chaperone mediated protein folding requiring
cofactor P
IDA
Ath At1g55490

GO:0051131 chaperone-mediated protein complex
assembly P
IMP
Sce S000004249
TAS
Ath At3g23990

GO:0051604 protein maturation P
IMP
Sce S000004249

GO:0061077 chaperone-mediated protein folding P
NAS
Spo SPAC12G12.04

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern

1626

Species Gene ID NCBI link UniProt link

Homo sapiens (Hsa) HSPD1 GI:41399285

Pan troglodytes (Ptr) HSPD1 GI:114582386

Canis familiaris (Cfa) HSPD1 GI:74005078

Mus musculus (Mmu) Hspd1
(MGI:96242) GI:31981679 P63038

Rattus norvegicus (Rno) Hspd1
(RGD:621314) GI:11560024

Gallus gallus (Gga) HSPD1 GI:61098372

Drosophila melanogaster (Dme) Hsp60
(FBgn0015245) GI:24641191

Anopheles gambiae (Aga) AgaP_AGAP004002 GI:58391242

Caenorhabditis elegans (Cel) hsp-60
(CE27244;
WBGene00002025) GI:17555558 P50140

Schizosaccharomyces pombe (Spo) hsp60 GI:19113806

Saccharomyces cerevisiae (Sce) HSP60
(S000004249) GI:6323288 P19882

Kluyveromyces lactis (Kla) KLLA0F09449g GI:50310975

Eremothecium gossypii (Ego) AGOS_AFR155W GI:45198673

Magnaporthe grisea (Mgr) MGG_03165 GI:145608376

Neurospora crassa (Ncr) NCU01589.1 GI:32415097

Arabidopsis thaliana (Ath) HSP60-2 GI:30685604

GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005615 extracellular space C
IDA
Hsa HSPD1

GO:0005737 cytoplasm C
ISO
Mmu MGI:96242

GO:0005739 mitochondrion C
IDA
Ath HSP60-2
Cel WBGene00002025
Dme FBgn0015245
Hsa HSPD1
Mmu MGI:96242
Sce S000004249
ISO
Mmu MGI:96242
ISS
Ath HSP60-2

GO:0005743 mitochondrial inner membrane C
IDA
Mmu MGI:96242
ISS
Hsa HSPD1

GO:0005759 mitochondrial matrix C
ISS
Dme FBgn0015245
NAS
Dme FBgn0015245
TAS
Hsa HSPD1

GO:0005769 early endosome C
IDA
Hsa HSPD1

GO:0005791 rough endoplasmic reticulum C
ISO
Mmu MGI:96242

GO:0005794 Golgi apparatus C
ISO
Mmu MGI:96242

GO:0005811 lipid particle C
IDA
Dme FBgn0015245

GO:0005829 cytosol C
IDA
Hsa HSPD1
ISO
Mmu MGI:96242

GO:0005875 microtubule associated complex C
IDA
Dme FBgn0015245

GO:0005886 plasma membrane C
IDA
Ath HSP60-2

GO:0005905 coated pit C
IDA
Hsa HSPD1

GO:0009507 chloroplast C
IDA
Ath HSP60-2

GO:0009986 cell surface C
IDA
Hsa HSPD1
ISO
Mmu MGI:96242

GO:0019907 cyclin-dependent protein kinase activating kinase
holoenzyme complex C
IDA
Hsa HSPD1

GO:0030061 mitochondrial crista C
ISO
Mmu MGI:96242

GO:0030135 coated vesicle C
IDA
Hsa HSPD1

GO:0030141 stored secretory granule C
IDA
Mmu MGI:96242
ISO
Mmu MGI:96242
ISS
Hsa HSPD1

GO:0031966 mitochondrial membrane C
RCA
Sce S000004249

GO:0042588 zymogen granule C
ISO
Mmu MGI:96242

GO:0042645 mitochondrial nucleoid C
IDA
Sce S000004249

GO:0043231 intracellular membrane-bounded
organelle C
IDA
Mmu MGI:96242

GO:0044459 plasma membrane part C
IDA
Mmu MGI:96242

GO:0045121 membrane raft C
ISO
Mmu MGI:96242

GO:0046696 lipopolysaccharide receptor complex C
IDA
Hsa HSPD1

GO:0001530 lipopolysaccharide binding F
IDA
Hsa HSPD1
Mmu MGI:96242

GO:0002020 protease binding F
ISO
Mmu MGI:96242

GO:0002039 p53 binding F
IPI
Hsa HSPD1

GO:0003688 DNA replication origin binding F
IDA
Sce S000004249
ISS
Hsa HSPD1

GO:0003697 single-stranded DNA binding F
IDA
Sce S000004249
ISS
Hsa HSPD1

GO:0005507 copper ion binding F
IDA
Ath HSP60-2

GO:0005515 protein binding F
IPI
Hsa HSPD1

GO:0005524 ATP binding F
IDA
Ath HSP60-2

GO:0008134 transcription factor binding F
IPI
Cel WBGene00002025

GO:0016887 ATPase activity F
IDA
Sce S000004249
ISS
Hsa HSPD1

GO:0032403 protein complex binding F
ISO
Mmu MGI:96242

GO:0043498 cell surface binding F
IDA
Hsa HSPD1

GO:0043559 insulin binding F
ISO
Mmu MGI:96242

GO:0046982 protein heterodimerization activity F
ISO
Mmu MGI:96242

GO:0051082 unfolded protein binding F
IC
Hsa HSPD1
IMP
Sce S000004249
ISS
Cel WBGene00002025
Dme FBgn0015245
Hsa HSPD1

GO:0051087 chaperone binding F
IPI
Hsa HSPD1
Sce S000004249

GO:0051787 misfolded protein binding F
ISO
Mmu MGI:96242

GO:0000003 reproduction P
IMP
Cel WBGene00002025

GO:0000302 response to reactive oxygen species P
IEP
Cel WBGene00002025

GO:0002119 nematode larval development P
IMP
Cel WBGene00002025

GO:0002236 detection of misfolded protein P
ISO
Mmu MGI:96242

GO:0002368 B cell cytokine production P
IDA
Hsa HSPD1

GO:0002755 MyD88-dependent toll-like receptor signaling
pathway P
IDA
Hsa HSPD1

GO:0002842 positive regulation of T cell mediated immune
response to tumor cell P
IDA
Hsa HSPD1

GO:0006082 organic acid metabolic process P
RCA
Sce S000004249

GO:0006457 protein folding P
ISS
Dme FBgn0015245
NAS
Dme FBgn0015245

GO:0006458 'de novo' protein folding P
IMP
Sce S000004249
ISS
Dme FBgn0015245
Hsa HSPD1

GO:0006626 protein targeting to mitochondrion P
ISS
Dme FBgn0015245

GO:0006916 anti-apoptosis P
ISO
Mmu MGI:96242

GO:0006919 activation of caspase activity P
IDA
Hsa HSPD1

GO:0006950 response to stress P
NAS
Dme FBgn0015245

GO:0006954 inflammatory response P
ISS
Ath HSP60-2

GO:0006986 response to unfolded protein P
IDA
Hsa HSPD1

GO:0007005 mitochondrion organization P
IMP
Cel WBGene00002025

GO:0009408 response to heat P
ISS
Dme FBgn0015245
NAS
Dme FBgn0015245

GO:0009792 embryo development ending in birth or egg
hatching P
IMP
Cel WBGene00002025

GO:0032727 positive regulation of interferon-alpha
production P
IDA
Hsa HSPD1
Mmu MGI:96242

GO:0032729 positive regulation of interferon-gamma
production P
IDA
Hsa HSPD1
Mmu MGI:96242
IGI
Mmu MGI:96242
ISO
Mmu MGI:96242
ISS
Hsa HSPD1

GO:0032733 positive regulation of interleukin-10
production P
IDA
Hsa HSPD1

GO:0032735 positive regulation of interleukin-12
production P
IDA
Hsa HSPD1

GO:0032755 positive regulation of interleukin-6
production P
IDA
Hsa HSPD1

GO:0034514 mitochondrial unfolded protein
response P
IEP
Cel WBGene00002025

GO:0042026 protein refolding P
IDA
Hsa HSPD1
Sce S000004249
IMP
Sce S000004249
NAS
Dme FBgn0015245

GO:0042100 B cell proliferation P
IDA
Hsa HSPD1

GO:0042110 T cell activation P
IDA
Hsa HSPD1
Mmu MGI:96242
IGI
Mmu MGI:96242
ISO
Mmu MGI:96242

GO:0042113 B cell activation P
IDA
Hsa HSPD1

GO:0043032 positive regulation of macrophage
activation P
IDA
Hsa HSPD1

GO:0043065 positive regulation of apoptosis P
IMP
Hsa HSPD1

GO:0043066 negative regulation of apoptosis P
IMP
Hsa HSPD1

GO:0045041 protein import into mitochondrial intermembrane
space P
IMP
Sce S000004249

GO:0045768 positive regulation of anti-apoptosis P
ISO
Mmu MGI:96242

GO:0048291 isotype switching to IgG isotypes P
IDA
Hsa HSPD1

GO:0050729 positive regulation of inflammatory
response P
ISO
Mmu MGI:96242

GO:0050821 protein stabilization P
IMP
Hsa HSPD1
Sce S000004249
ISS
Hsa HSPD1

GO:0050870 positive regulation of T cell activation P
IDA
Hsa HSPD1
Mmu MGI:96242
ISS
Hsa HSPD1

GO:0051085 chaperone mediated protein folding requiring
cofactor P
ISO
Mmu MGI:96242

GO:0051131 chaperone-mediated protein complex
assembly P
IMP
Sce S000004249
ISS
Hsa HSPD1

GO:0051604 protein maturation P
IMP
Sce S000004249
ISS
Hsa HSPD1

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern

OG1_552

Species OrthoMCL
sequence Model organism
protein page UniProt link

Anopheles gambiae (Aga) aga6512 ENSANGP00000014839

Ashbya gossypii (Ago) ago3347 AFR155W

Arabidopsis thaliana (Ath) ath10348 At2g33210.1

Arabidopsis thaliana (Ath) ath13572 At3g13860.1

Arabidopsis thaliana (Ath) ath14721 At3g23990.1

Caenorhabditis elegans (Cel) cel17979 Y22D7AL.5

Candida glabrata (Cgl) cgl3777 CAGL0K05973g

Cryptococcus neoformans (Cne) cne4915 186.m03822

Dictyostelium discoideum (Ddi) ddi13006 DDB0219929

Debaryomyces hansenii (Dha) dha3531 DEHA0E06589g

Drosophila melanogaster (Dme) dme17358 CG12101-PA
(FBgn0015245)

Drosophila melanogaster (Dme) dme17359 CG12101-PB
(FBgn0015245)

Danio rerio (Dre) dre23714 ENSDARP00000039630

Danio rerio (Dre) dre23713 ENSDARP00000046243

Escherichia coli (Eco) eco3987 16131968

Takifugu rubripes (Fru) fru32256 SINFRUP00000143901

Gallus gallus (Gga) gga21297 ENSGALP00000013122
(HSPD1) Q5ZL72

Homo sapiens (Hsa) hsa19047 ENSP00000272817

Homo sapiens (Hsa) hsa19048 ENSP00000340019
(HSPD1) P10809

Kluyveromyces lactis (Kla) kla4510 KLLA0F09449g

Mus musculus (Mmu) mmu351 ENSMUSP00000027123
(MGI:96242) P63038-1

Mus musculus (Mmu) mmu3449 ENSMUSP00000073606

Neurospora crassa (Ncr) ncr1543 NCU01589.2

Oryza sativa (Osa) osa40463 5187.m00183

Oryza sativa (Osa) osa73791 7279.m00120

Oryza sativa (Osa) osa78785 7390.m00132

Oryza sativa (Osa) osa77924 7478.m00108

Plasmodium falciparum (Pfa) pfa374 PF10_0153

Rattus norvegicus (Rno) rno30046 ENSRNOP00000019912
(RGD:621314) P63039

Saccharomyces cerevisiae (Sce) sce4363 YLR259C
(S000004249)

Schizosaccharomyces pombe (Spo) spo3031 SPAC12G12.04 Q09864

Yarrowia lipolytica (Yli) yli5454 YALI0F02805g

GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005737 cytoplasm C
ISO
Mmu MGI:96242

GO:0005739 mitochondrion C
IDA
Ath At3g13860
At2g33210
At3g23990
Dme FBgn0015245
Mmu MGI:96242
Sce S000004249
Spo SPAC12G12.04
ISO
Mmu MGI:96242
ISS
Ath At2g33210
Pfa PF10_0153
Spo SPAC12G12.04

GO:0005743 mitochondrial inner membrane C
IDA
Mmu MGI:96242

GO:0005759 mitochondrial matrix C
IDA
Ath At3g23990
ISS
Dme FBgn0015245
NAS
Dme FBgn0015245

GO:0005791 rough endoplasmic reticulum C
ISO
Mmu MGI:96242

GO:0005794 Golgi apparatus C
ISO
Mmu MGI:96242

GO:0005811 lipid particle C
IDA
Dme FBgn0015245

GO:0005829 cytosol C
IDA
Ath At3g23990
ISO
Mmu MGI:96242

GO:0005875 microtubule associated complex C
IDA
Dme FBgn0015245

GO:0005886 plasma membrane C
IDA
Ath At2g33210
At3g13860
At3g23990

GO:0009507 chloroplast C
IDA
Ath At2g33210

GO:0009986 cell surface C
ISO
Mmu MGI:96242

GO:0022626 cytosolic ribosome C
IDA
Ath At3g23990

GO:0030061 mitochondrial crista C
ISO
Mmu MGI:96242

GO:0030141 stored secretory granule C
IDA
Mmu MGI:96242
ISO
Mmu MGI:96242

GO:0031966 mitochondrial membrane C
RCA
Sce S000004249

GO:0042588 zymogen granule C
ISO
Mmu MGI:96242

GO:0042645 mitochondrial nucleoid C
IDA
Sce S000004249
ISS
Spo SPAC12G12.04

GO:0043231 intracellular membrane-bounded
organelle C
IDA
Mmu MGI:96242

GO:0044459 plasma membrane part C
IDA
Mmu MGI:96242

GO:0045121 membrane raft C
ISO
Mmu MGI:96242

GO:0001530 lipopolysaccharide binding F
IDA
Mmu MGI:96242

GO:0002020 protease binding F
ISO
Mmu MGI:96242

GO:0003688 DNA replication origin binding F
IDA
Sce S000004249

GO:0003697 single-stranded DNA binding F
IDA
Sce S000004249
ISS
Spo SPAC12G12.04

GO:0005507 copper ion binding F
IDA
Ath At2g33210
At3g23990

GO:0005524 ATP binding F
IDA
Ath At2g33210
At3g23990
ISS
Spo SPAC12G12.04

GO:0016887 ATPase activity F
IDA
Sce S000004249

GO:0032403 protein complex binding F
ISO
Mmu MGI:96242

GO:0042623 ATPase activity, coupled F
ISS
Pfa PF10_0153

GO:0043559 insulin binding F
ISO
Mmu MGI:96242

GO:0046982 protein heterodimerization activity F
ISO
Mmu MGI:96242

GO:0051082 unfolded protein binding F
IMP
Sce S000004249
ISS
Dme FBgn0015245

GO:0051087 chaperone binding F
IPI
Sce S000004249

GO:0051787 misfolded protein binding F
ISO
Mmu MGI:96242

GO:0002236 detection of misfolded protein P
ISO
Mmu MGI:96242

GO:0006082 organic acid metabolic process P
RCA
Sce S000004249

GO:0006457 protein folding P
ISS
Dme FBgn0015245
Spo SPAC12G12.04
NAS
Dme FBgn0015245

GO:0006458 'de novo' protein folding P
IMP
Sce S000004249
ISS
Dme FBgn0015245

GO:0006626 protein targeting to mitochondrion P
ISS
Dme FBgn0015245
Pfa PF10_0153

GO:0006916 anti-apoptosis P
ISO
Mmu MGI:96242

GO:0006950 response to stress P
NAS
Dme FBgn0015245

GO:0006954 inflammatory response P
ISS
Ath At2g33210

GO:0006986 response to unfolded protein P
ISS
Pfa PF10_0153

GO:0007005 mitochondrion organization P
TAS
Ath At3g23990

GO:0009408 response to heat P
IEP
Ath At3g23990
ISS
Dme FBgn0015245
NAS
Dme FBgn0015245

GO:0030150 protein import into mitochondrial
matrix P
ISS
Spo SPAC12G12.04

GO:0032727 positive regulation of interferon-alpha
production P
IDA
Mmu MGI:96242

GO:0032729 positive regulation of interferon-gamma
production P
IDA
Mmu MGI:96242
IGI
Mmu MGI:96242
ISO
Mmu MGI:96242

GO:0034605 cellular response to heat P
IEP
Spo SPAC12G12.04

GO:0042026 protein refolding P
IDA
Sce S000004249
IMP
Sce S000004249
NAS
Dme FBgn0015245

GO:0042110 T cell activation P
IDA
Mmu MGI:96242
IGI
Mmu MGI:96242
ISO
Mmu MGI:96242

GO:0045041 protein import into mitochondrial intermembrane
space P
IMP
Sce S000004249

GO:0045768 positive regulation of anti-apoptosis P
ISO
Mmu MGI:96242

GO:0046686 response to cadmium ion P
IEP
Ath At3g13860
At3g23990

GO:0050729 positive regulation of inflammatory
response P
ISO
Mmu MGI:96242

GO:0050821 protein stabilization P
IMP
Sce S000004249

GO:0050870 positive regulation of T cell activation P
IDA
Mmu MGI:96242

GO:0051085 chaperone mediated protein folding requiring
cofactor P
ISO
Mmu MGI:96242

GO:0051131 chaperone-mediated protein complex
assembly P
IMP
Sce S000004249
TAS
Ath At3g23990

GO:0051604 protein maturation P
IMP
Sce S000004249

GO:0061077 chaperone-mediated protein folding P
NAS
Spo SPAC12G12.04

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Curated yeast ortholog results:

S. pombe
systematic ID S. cerevisiae
systematic ID

SPAC12G12.04
(Q09864) YLR259C
(S000004249)

GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations

GO:0005739 mitochondrion C
IDA
Sce S000004249
Spo SPAC12G12.04
ISS
Spo SPAC12G12.04

GO:0031966 mitochondrial membrane C
RCA
Sce S000004249

GO:0042645 mitochondrial nucleoid C
IDA
Sce S000004249
ISS
Spo SPAC12G12.04

GO:0003688 DNA replication origin binding F
IDA
Sce S000004249

GO:0003697 single-stranded DNA binding F
IDA
Sce S000004249
ISS
Spo SPAC12G12.04

GO:0005524 ATP binding F
ISS
Spo SPAC12G12.04

GO:0016887 ATPase activity F
IDA
Sce S000004249

GO:0051082 unfolded protein binding F
IMP
Sce S000004249

GO:0051087 chaperone binding F
IPI
Sce S000004249

GO:0006082 organic acid metabolic process P
RCA
Sce S000004249

GO:0006457 protein folding P
ISS
Spo SPAC12G12.04

GO:0006458 'de novo' protein folding P
IMP
Sce S000004249

GO:0030150 protein import into mitochondrial
matrix P
ISS
Spo SPAC12G12.04

GO:0034605 cellular response to heat P
IEP
Spo SPAC12G12.04

GO:0042026 protein refolding P
IDA
Sce S000004249
IMP
Sce S000004249

GO:0045041 protein import into mitochondrial intermembrane
space P
IMP
Sce S000004249

GO:0050821 protein stabilization P
IMP
Sce S000004249

GO:0051131 chaperone-mediated protein complex
assembly P
IMP
Sce S000004249

GO:0051604 protein maturation P
IMP
Sce S000004249

GO:0061077 chaperone-mediated protein folding P
NAS
Spo SPAC12G12.04

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YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards: Yes No

Search for GO info: Yes No

GO info in one table: Yes No

s.khadayate@ucl.ac.uk

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG0356	ACDHYP-

KOGs classification	KOGs description
CELLULAR PROCESSES AND SIGNALING	Mitochondrial chaperonin, Cpn60/Hsp60p

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At1g26230	GI:15222666
Arabidopsis thaliana (Ath)	At1g55490	GI:15222729
Arabidopsis thaliana (Ath)	At2g28000	GI:15226314
Arabidopsis thaliana (Ath)	At2g33210	GI:15225813
Arabidopsis thaliana (Ath)	At3g13470	GI:15231255
Arabidopsis thaliana (Ath)	At3g13860	GI:15231389
Arabidopsis thaliana (Ath)	At3g23990	GI:15229559
Arabidopsis thaliana (Ath)	At5g18820	GI:15239580
Arabidopsis thaliana (Ath)	At5g56500	GI:15241234
Caenorhabditis elegans (Cel)	CE27244 (WBGene00002025)	GI:17555558	P50140
Drosophila melanogaster (Dme)	7292599	GI:12644042
Drosophila melanogaster (Dme)	7296174	GI:17864606
Drosophila melanogaster (Dme)	7297006	GI:20129251
Drosophila melanogaster (Dme)	7298068	GI:19921262	Q9VJX7
Homo sapiens (Hsa)	Hs12737357	GI:12737357
Homo sapiens (Hsa)	Hs17445889	GI:17445889
Homo sapiens (Hsa)	Hs17448210	GI:17448210
Homo sapiens (Hsa)	Hs17453047	GI:17453047
Homo sapiens (Hsa)	Hs17455076	GI:17455076
Homo sapiens (Hsa)	Hs18569024	GI:18569024
Homo sapiens (Hsa)	Hs18582452_1	GI:18582452
Homo sapiens (Hsa)	Hs22041202	GI:22041202
Homo sapiens (Hsa)	Hs20540570	GI:20540570
Homo sapiens (Hsa)	Hs4504521	GI:4504521
Saccharomyces cerevisiae (Sce)	YBR044c (S000000248)	GI:6319518	P38228
Saccharomyces cerevisiae (Sce)	YLR259c (S000004249)	GI:6323288	P19882
Schizosaccharomyces pombe (Spo)	SPAC12G12.04	GI:19113806	Q09864
Arabidopsis thaliana (Ath)	At1g26230	GI:15222666
Arabidopsis thaliana (Ath)	At1g55490	GI:15222729
Arabidopsis thaliana (Ath)	At2g28000	GI:15226314
Arabidopsis thaliana (Ath)	At2g33210	GI:15225813
Arabidopsis thaliana (Ath)	At3g13470	GI:15231255
Arabidopsis thaliana (Ath)	At3g13860	GI:15231389
Arabidopsis thaliana (Ath)	At3g23990	GI:15229559
Arabidopsis thaliana (Ath)	At5g18820	GI:15239580
Arabidopsis thaliana (Ath)	At5g56500	GI:15241234
Caenorhabditis elegans (Cel)	CE27244 (WBGene00002025)	GI:17555558	P50140
Drosophila melanogaster (Dme)	7292599	GI:12644042
Drosophila melanogaster (Dme)	7296174	GI:17864606
Drosophila melanogaster (Dme)	7297006	GI:20129251
Drosophila melanogaster (Dme)	7298068	GI:19921262	Q9VJX7
Homo sapiens (Hsa)	Hs12737357	GI:12737357
Homo sapiens (Hsa)	Hs17445889	GI:17445889
Homo sapiens (Hsa)	Hs17448210	GI:17448210
Homo sapiens (Hsa)	Hs17453047	GI:17453047
Homo sapiens (Hsa)	Hs17455076	GI:17455076
Homo sapiens (Hsa)	Hs18569024	GI:18569024
Homo sapiens (Hsa)	Hs18582452_1	GI:18582452
Homo sapiens (Hsa)	Hs22041202	GI:22041202
Homo sapiens (Hsa)	Hs20540570	GI:20540570
Homo sapiens (Hsa)	Hs4504521	GI:4504521
Saccharomyces cerevisiae (Sce)	YBR044c (S000000248)	GI:6319518	P38228
Saccharomyces cerevisiae (Sce)	YLR259c (S000004249)	GI:6323288	P19882
Schizosaccharomyces pombe (Spo)	SPAC12G12.04	GI:19113806	Q09864
Arabidopsis thaliana (Ath)	At1g26230	GI:15222666
Arabidopsis thaliana (Ath)	At1g55490	GI:15222729
Arabidopsis thaliana (Ath)	At2g28000	GI:15226314
Arabidopsis thaliana (Ath)	At2g33210	GI:15225813
Arabidopsis thaliana (Ath)	At3g13470	GI:15231255
Arabidopsis thaliana (Ath)	At3g13860	GI:15231389
Arabidopsis thaliana (Ath)	At3g23990	GI:15229559
Arabidopsis thaliana (Ath)	At5g18820	GI:15239580
Arabidopsis thaliana (Ath)	At5g56500	GI:15241234
Caenorhabditis elegans (Cel)	CE27244 (WBGene00002025)	GI:17555558	P50140
Drosophila melanogaster (Dme)	7292599	GI:12644042
Drosophila melanogaster (Dme)	7296174	GI:17864606
Drosophila melanogaster (Dme)	7297006	GI:20129251
Drosophila melanogaster (Dme)	7298068	GI:19921262	Q9VJX7
Homo sapiens (Hsa)	Hs12737357	GI:12737357
Homo sapiens (Hsa)	Hs17445889	GI:17445889
Homo sapiens (Hsa)	Hs17448210	GI:17448210
Homo sapiens (Hsa)	Hs17453047	GI:17453047
Homo sapiens (Hsa)	Hs17455076	GI:17455076
Homo sapiens (Hsa)	Hs18569024	GI:18569024
Homo sapiens (Hsa)	Hs18582452_1	GI:18582452
Homo sapiens (Hsa)	Hs22041202	GI:22041202
Homo sapiens (Hsa)	Hs20540570	GI:20540570
Homo sapiens (Hsa)	Hs4504521	GI:4504521
Saccharomyces cerevisiae (Sce)	YBR044c (S000000248)	GI:6319518	P38228
Saccharomyces cerevisiae (Sce)	YLR259c (S000004249)	GI:6323288	P19882
Schizosaccharomyces pombe (Spo)	SPAC12G12.04	GI:19113806	Q09864

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	HSPD1	GI:41399285
Pan troglodytes (Ptr)	HSPD1	GI:114582386
Canis familiaris (Cfa)	HSPD1	GI:74005078
Mus musculus (Mmu)	Hspd1 (MGI:96242)	GI:31981679	P63038
Rattus norvegicus (Rno)	Hspd1 (RGD:621314)	GI:11560024
Gallus gallus (Gga)	HSPD1	GI:61098372
Drosophila melanogaster (Dme)	Hsp60 (FBgn0015245)	GI:24641191
Anopheles gambiae (Aga)	AgaP_AGAP004002	GI:58391242
Caenorhabditis elegans (Cel)	hsp-60 (CE27244; WBGene00002025)	GI:17555558	P50140
Schizosaccharomyces pombe (Spo)	hsp60	GI:19113806
Saccharomyces cerevisiae (Sce)	HSP60 (S000004249)	GI:6323288	P19882
Kluyveromyces lactis (Kla)	KLLA0F09449g	GI:50310975
Eremothecium gossypii (Ego)	AGOS_AFR155W	GI:45198673
Magnaporthe grisea (Mgr)	MGG_03165	GI:145608376
Neurospora crassa (Ncr)	NCU01589.1	GI:32415097
Arabidopsis thaliana (Ath)	HSP60-2	GI:30685604

Species	OrthoMCL sequence	Model organism protein page	UniProt link
Anopheles gambiae (Aga)	aga6512	ENSANGP00000014839
Ashbya gossypii (Ago)	ago3347	AFR155W
Arabidopsis thaliana (Ath)	ath10348	At2g33210.1
Arabidopsis thaliana (Ath)	ath13572	At3g13860.1
Arabidopsis thaliana (Ath)	ath14721	At3g23990.1
Caenorhabditis elegans (Cel)	cel17979	Y22D7AL.5
Candida glabrata (Cgl)	cgl3777	CAGL0K05973g
Cryptococcus neoformans (Cne)	cne4915	186.m03822
Dictyostelium discoideum (Ddi)	ddi13006	DDB0219929
Debaryomyces hansenii (Dha)	dha3531	DEHA0E06589g
Drosophila melanogaster (Dme)	dme17358	CG12101-PA (FBgn0015245)
Drosophila melanogaster (Dme)	dme17359	CG12101-PB (FBgn0015245)
Danio rerio (Dre)	dre23714	ENSDARP00000039630
Danio rerio (Dre)	dre23713	ENSDARP00000046243
Escherichia coli (Eco)	eco3987	16131968
Takifugu rubripes (Fru)	fru32256	SINFRUP00000143901
Gallus gallus (Gga)	gga21297	ENSGALP00000013122 (HSPD1)	Q5ZL72
Homo sapiens (Hsa)	hsa19047	ENSP00000272817
Homo sapiens (Hsa)	hsa19048	ENSP00000340019 (HSPD1)	P10809
Kluyveromyces lactis (Kla)	kla4510	KLLA0F09449g
Mus musculus (Mmu)	mmu351	ENSMUSP00000027123 (MGI:96242)	P63038-1
Mus musculus (Mmu)	mmu3449	ENSMUSP00000073606
Neurospora crassa (Ncr)	ncr1543	NCU01589.2
Oryza sativa (Osa)	osa40463	5187.m00183
Oryza sativa (Osa)	osa73791	7279.m00120
Oryza sativa (Osa)	osa78785	7390.m00132
Oryza sativa (Osa)	osa77924	7478.m00108
Plasmodium falciparum (Pfa)	pfa374	PF10_0153
Rattus norvegicus (Rno)	rno30046	ENSRNOP00000019912 (RGD:621314)	P63039
Saccharomyces cerevisiae (Sce)	sce4363	YLR259C (S000004249)
Schizosaccharomyces pombe (Spo)	spo3031	SPAC12G12.04	Q09864
Yarrowia lipolytica (Yli)	yli5454	YALI0F02805g

S. pombe systematic ID	S. cerevisiae systematic ID
SPAC12G12.04 (Q09864)	YLR259C (S000004249)