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Search term: YLR288C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MEC3
SGD link S000004279
Alternative ID YLR288C
Description DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1
Synonyms YLR288C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39761

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MEC3
(S000004279)
GI:6323319
Kluyveromyces lactis (Kla) KLLA0C04840g GI:50304921
Eremothecium gossypii (Ego) AGOS_AGR289C GI:45201385


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
TAS
SceS000004279
GO:0030896 checkpoint clamp complex C
IDA
SceS000004279
GO:0003677 DNA binding F
IDA
SceS000004279
GO:0000077 DNA damage checkpoint P
IMP
SceS000004279
GO:0000722 telomere maintenance via recombination P
IGI
SceS000004279
GO:0006259 DNA metabolic process P
TAS
SceS000004279
GO:0006348 chromatin silencing at telomere P
IMP
SceS000004279

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24602

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago4600 AGR289C
Candida glabrata (Cgl) cgl5081 CAGL0M09735g
Debaryomyces hansenii (Dha) dha4495 DEHA0F02442g
Kluyveromyces lactis (Kla) kla1415 KLLA0C04840g
Saccharomyces cerevisiae (Sce) sce4397 YLR288C
(S000004279)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
TAS
SceS000004279
GO:0030896 checkpoint clamp complex C
IDA
SceS000004279
GO:0003677 DNA binding F
IDA
SceS000004279
GO:0000077 DNA damage checkpoint P
IMP
SceS000004279
GO:0000722 telomere maintenance via recombination P
IGI
SceS000004279
GO:0006259 DNA metabolic process P
TAS
SceS000004279
GO:0006348 chromatin silencing at telomere P
IMP
SceS000004279

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC20G4.04c
(P78955)
YLR288C
(S000004279)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC20G4.04c
TAS
SceS000004279
GO:0005730 nucleolus C
IDA
SpoSPAC20G4.04c
GO:0005816 spindle pole body C
IDA
SpoSPAC20G4.04c
GO:0005829 cytosol C
IDA
SpoSPAC20G4.04c
GO:0030896 checkpoint clamp complex C
IDA
SceS000004279
SpoSPAC20G4.04c
GO:0003677 DNA binding F
IDA
SceS000004279
GO:0005515 protein binding F
IPI
SpoSPAC20G4.04c
GO:0000076 DNA replication checkpoint P
TAS
SpoSPAC20G4.04c
GO:0000077 DNA damage checkpoint P
IMP
SceS000004279
TAS
SpoSPAC20G4.04c
GO:0000722 telomere maintenance via recombination P
IGI
SceS000004279
GO:0006259 DNA metabolic process P
TAS
SceS000004279
GO:0006348 chromatin silencing at telomere P
IMP
SceS000004279
GO:0031573 intra-S DNA damage checkpoint P
IMP
SpoSPAC20G4.04c
GO:0031574 S-M checkpoint P
IMP
SpoSPAC20G4.04c

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