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Search term: YLR298C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name YHC1
SGD link S000004289
Alternative ID YLR298C
Description Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C protein, which is involved in formation of a complex between U1 snRNP and the pre-mRNA 5' splice site
Synonyms YLR298C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3454 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING U1 snRNP-specific protein C

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g03120 GI:4262140
Caenorhabditis elegans (Cel) CE09232
(WBGene00017238)		 GI:17539712 P90815
Drosophila melanogaster (Dme) 7300460 GI:7300460
Homo sapiens (Hsa) Hs22052125 GI:22052125
Homo sapiens (Hsa) Hs4507127
(SNRPC)		 GI:4507127 P09234
Homo sapiens (Hsa) Hs9506863 GI:9506863 Q9UDW3
Saccharomyces cerevisiae (Sce) YLR298c
(S000004289)		 GI:6323329 Q05900
Schizosaccharomyces pombe (Spo) SPBP35G2.09 GI:19112176 Q9P794
Encephalitozoon cuniculi (Ecu) ECU10g0290 GI:19074638 Q8SR72


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000243 commitment complex C
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0005634 nucleus C
IDA
SpoSPBP35G2.09
GO:0005685 U1 snRNP C
IDA
HsaSNRPC
SceS000004289
SpoSPBP35G2.09
GO:0005829 cytosol C
IDA
SpoSPBP35G2.09
GO:0015030 Cajal body C
IDA
HsaSNRPC
GO:0071004 U2-type prespliceosome C
IDA
SceS000004289
GO:0003727 single-stranded RNA binding F
IDA
HsaSNRPC
GO:0003729 mRNA binding F
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0005515 protein binding F
IPI
HsaSNRPC
GO:0008270 zinc ion binding F
IDA
HsaSNRPC
GO:0042803 protein homodimerization activity F
IPI
HsaSNRPC
GO:0000003 reproduction P
IMP
CelWBGene00017238
GO:0000387 spliceosomal snRNP assembly P
IDA
HsaSNRPC
GO:0000395 nuclear mRNA 5'-splice site recognition P
IC
SpoSPBP35G2.09
GO:0000398 nuclear mRNA splicing, via spliceosome P
IDA
HsaSNRPC
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00017238
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00017238
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00017238
GO:0016071 mRNA metabolic process P
RCA
SceS000004289
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00017238

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48905

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) YHC1
(S000004289)		 GI:6323329 Q05900
Kluyveromyces lactis (Kla) KLLA0C05192g GI:50304949
Kluyveromyces lactis (Kla) KLLA0A04565g GI:50302531
Eremothecium gossypii (Ego) AGOS_AAR142C GI:45184966


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000243 commitment complex C
IPI
SceS000004289
GO:0005685 U1 snRNP C
IDA
SceS000004289
GO:0071004 U2-type prespliceosome C
IDA
SceS000004289
GO:0003729 mRNA binding F
IPI
SceS000004289
GO:0000398 nuclear mRNA splicing, via spliceosome P
IPI
SceS000004289
GO:0016071 mRNA metabolic process P
RCA
SceS000004289

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2397

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3688 ENSANGP00000018169
Ashbya gossypii (Ago) ago329 AAR142C
Arabidopsis thaliana (Ath) ath18207 At4g03120.1
Caenorhabditis elegans (Cel) cel5626 F08B4.7
(CE09232;
WBGene00017238)
Candida glabrata (Cgl) cgl2547 CAGL0I00528g
Cryptococcus neoformans (Cne) cne153 162.m02633
Dictyostelium discoideum (Ddi) ddi5824 DDB0205382
Drosophila melanogaster (Dme) dme13321 CG5454-PA
(FBgn0038667)
Danio rerio (Dre) dre27756 ENSDARP00000010253
(snrpc)		 Q8JGS0
Gallus gallus (Gga) gga13590 ENSGALP00000004369
(SNRPC)
Gallus gallus (Gga) gga13591 ENSGALP00000004370
Homo sapiens (Hsa) hsa26988 ENSP00000244520
(SNRPC)		 P09234
Homo sapiens (Hsa) hsa25407 ENSP00000305492
Kluyveromyces lactis (Kla) kla197 KLLA0A04565g
Kluyveromyces lactis (Kla) kla1431 KLLA0C05192g
Mus musculus (Mmu) mmu11258 ENSMUSP00000025056
Mus musculus (Mmu) mmu11259 ENSMUSP00000063976
(MGI:109489)		 Q62241
Mus musculus (Mmu) mmu9054 ENSMUSP00000076754
Neurospora crassa (Ncr) ncr1300 NCU01341.2
Oryza sativa (Osa) osa20811 3635.m00289
Plasmodium falciparum (Pfa) pfa2178 PF08_0084
Rattus norvegicus (Rno) rno17572 ENSRNOP00000000586
(RGD:1306065)
Rattus norvegicus (Rno) rno4656 ENSRNOP00000023626
Saccharomyces cerevisiae (Sce) sce4407 YLR298C
(S000004289)
Schizosaccharomyces pombe (Spo) spo376 SPBP35G2.09 Q9P794


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000243 commitment complex C
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0005575 cellular_component C
ND
MmuMGI:109489
GO:0005634 nucleus C
IDA
SpoSPBP35G2.09
GO:0005685 U1 snRNP C
IDA
SceS000004289
SpoSPBP35G2.09
GO:0005829 cytosol C
IDA
SpoSPBP35G2.09
GO:0071004 U2-type prespliceosome C
IDA
SceS000004289
GO:0003674 molecular_function F
ND
MmuMGI:109489
GO:0003729 mRNA binding F
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0000003 reproduction P
IMP
CelWBGene00017238
GO:0000395 nuclear mRNA 5'-splice site recognition P
IC
SpoSPBP35G2.09
GO:0000398 nuclear mRNA splicing, via spliceosome P
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00017238
GO:0008150 biological_process P
ND
MmuMGI:109489
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00017238
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00017238
GO:0016071 mRNA metabolic process P
RCA
SceS000004289
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00017238

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBP35G2.09
(Q9P794)		 YLR298C
(S000004289)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000243 commitment complex C
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0005634 nucleus C
IDA
SpoSPBP35G2.09
GO:0005685 U1 snRNP C
IDA
SceS000004289
SpoSPBP35G2.09
GO:0005829 cytosol C
IDA
SpoSPBP35G2.09
GO:0071004 U2-type prespliceosome C
IDA
SceS000004289
GO:0003729 mRNA binding F
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0000395 nuclear mRNA 5'-splice site recognition P
IC
SpoSPBP35G2.09
GO:0000398 nuclear mRNA splicing, via spliceosome P
IPI
SceS000004289
ISS
SpoSPBP35G2.09
GO:0016071 mRNA metabolic process P
RCA
SceS000004289

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GO info in one table:

s.khadayate@ucl.ac.uk