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Search term: YLR303W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MET17
SGD link S000004294
Alternative ID YLR303W
Description Methionine and cysteine synthase (O-acetyl homoserine-O-acetyl serine sulfhydrylase), required for sulfur amino acid synthesis
Synonyms YLR303W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0053 ACDHYP-

KOGs classification KOGs description
METABOLISM Cystathionine beta-lyases/cystathionine gamma-synthases

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g33320 GI:15217498
Arabidopsis thaliana (Ath) At1g64660 GI:15217709
Arabidopsis thaliana (Ath) At3g01120 GI:15232042
Arabidopsis thaliana (Ath) At3g57050 GI:15230203
Caenorhabditis elegans (Cel) CE07648
(WBGene00022856)		 GI:17538055 P55216
Caenorhabditis elegans (Cel) CE15884
(WBGene00009048)		 GI:17560056 O45391
Caenorhabditis elegans (Cel) CE17400 GI:17505573
Drosophila melanogaster (Dme) 7302582
(FBgn0000566)		 GI:19922554
Homo sapiens (Hsa) Hs21361334 GI:12314252 P32929
Homo sapiens (Hsa) HsM4503125 GI:4503125
Saccharomyces cerevisiae (Sce) YAL012w
(S000000010)		 GI:6319307 P31373
Saccharomyces cerevisiae (Sce) YFR055w
(S000001952)		 GI:14318580 P43623
Saccharomyces cerevisiae (Sce) YGL184c
(S000003152)		 GI:6321254 P53101
Saccharomyces cerevisiae (Sce) YHR112c GI:6321904 P38716
Saccharomyces cerevisiae (Sce) YJR130c
(S000003891)		 GI:6322590 P47164
Saccharomyces cerevisiae (Sce) YLL058w GI:6322970 Q12198
Saccharomyces cerevisiae (Sce) YLR303w
(S000004294)		 GI:6323333 P06106
Saccharomyces cerevisiae (Sce) YML082w GI:6323557 Q04533
Schizosaccharomyces pombe (Spo) SPAC23A1.14c GI:19115355 O42851
Schizosaccharomyces pombe (Spo) SPBC15D4.09c GI:19113041 O74314
Schizosaccharomyces pombe (Spo) SPBC428.11 GI:19111981 O13326
Schizosaccharomyces pombe (Spo) SPCC11E10.01 GI:19075697 O94350
Arabidopsis thaliana (Ath) At1g33320 GI:15217498
Arabidopsis thaliana (Ath) At1g64660 GI:15217709
Arabidopsis thaliana (Ath) At3g01120 GI:15232042
Arabidopsis thaliana (Ath) At3g57050 GI:15230203
Caenorhabditis elegans (Cel) CE07648
(WBGene00022856)		 GI:17538055 P55216
Caenorhabditis elegans (Cel) CE15884
(WBGene00009048)		 GI:17560056 O45391
Caenorhabditis elegans (Cel) CE17400 GI:17505573
Drosophila melanogaster (Dme) 7302582
(FBgn0000566)		 GI:19922554
Homo sapiens (Hsa) Hs21361334 GI:12314252 P32929
Homo sapiens (Hsa) HsM4503125 GI:4503125
Saccharomyces cerevisiae (Sce) YAL012w
(S000000010)		 GI:6319307 P31373
Saccharomyces cerevisiae (Sce) YFR055w
(S000001952)		 GI:14318580 P43623
Saccharomyces cerevisiae (Sce) YGL184c
(S000003152)		 GI:6321254 P53101
Saccharomyces cerevisiae (Sce) YHR112c GI:6321904 P38716
Saccharomyces cerevisiae (Sce) YJR130c
(S000003891)		 GI:6322590 P47164
Saccharomyces cerevisiae (Sce) YLL058w GI:6322970 Q12198
Saccharomyces cerevisiae (Sce) YLR303w
(S000004294)		 GI:6323333 P06106
Saccharomyces cerevisiae (Sce) YML082w GI:6323557 Q04533
Schizosaccharomyces pombe (Spo) SPAC23A1.14c GI:19115355 O42851
Schizosaccharomyces pombe (Spo) SPBC15D4.09c GI:19113041 O74314
Schizosaccharomyces pombe (Spo) SPBC428.11 GI:19111981 O13326
Schizosaccharomyces pombe (Spo) SPCC11E10.01 GI:19075697 O94350
Arabidopsis thaliana (Ath) At1g33320 GI:15217498
Arabidopsis thaliana (Ath) At1g64660 GI:15217709
Arabidopsis thaliana (Ath) At3g01120 GI:15232042
Arabidopsis thaliana (Ath) At3g57050 GI:15230203
Caenorhabditis elegans (Cel) CE07648
(WBGene00022856)		 GI:17538055 P55216
Caenorhabditis elegans (Cel) CE15884
(WBGene00009048)		 GI:17560056 O45391
Caenorhabditis elegans (Cel) CE17400 GI:17505573
Drosophila melanogaster (Dme) 7302582
(FBgn0000566)		 GI:19922554
Homo sapiens (Hsa) Hs21361334 GI:12314252 P32929
Homo sapiens (Hsa) HsM4503125 GI:4503125
Saccharomyces cerevisiae (Sce) YAL012w
(S000000010)		 GI:6319307 P31373
Saccharomyces cerevisiae (Sce) YFR055w
(S000001952)		 GI:14318580 P43623
Saccharomyces cerevisiae (Sce) YGL184c
(S000003152)		 GI:6321254 P53101
Saccharomyces cerevisiae (Sce) YHR112c GI:6321904 P38716
Saccharomyces cerevisiae (Sce) YJR130c
(S000003891)		 GI:6322590 P47164
Saccharomyces cerevisiae (Sce) YLL058w GI:6322970 Q12198
Saccharomyces cerevisiae (Sce) YLR303w
(S000004294)		 GI:6323333 P06106
Saccharomyces cerevisiae (Sce) YML082w GI:6323557 Q04533
Schizosaccharomyces pombe (Spo) SPAC23A1.14c GI:19115355 O42851
Schizosaccharomyces pombe (Spo) SPBC15D4.09c GI:19113041 O74314
Schizosaccharomyces pombe (Spo) SPBC428.11 GI:19111981 O13326
Schizosaccharomyces pombe (Spo) SPCC11E10.01 GI:19075697 O94350


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000004294
GO:0005575 cellular_component C
ND
SceS000003152
YLL058w
S000001952
SpoSPAC23A1.14c
GO:0005634 nucleus C
IDA
SceS000003891
YML082w
SpoSPBC15D4.09c
SPBC428.11
ISS
SpoSPBC15D4.09c
GO:0005737 cytoplasm C
IDA
SceYHR112c
YML082w
S000003891
S000004294
S000000010
ISS
SpoSPBC15D4.09c
SPBC428.11
GO:0005777 peroxisome C
ISS
SpoSPCC11E10.01
GO:0005829 cytosol C
IDA
AthAt1g64660
SpoSPBC15D4.09c
SPBC428.11
GO:0009507 chloroplast C
IDA
AthAt3g57050
At3g01120
ISS
AthAt3g57050
GO:0003824 catalytic activity F
ISS
AthAt1g64660
GO:0003961 O-acetylhomoserine aminocarboxypropyltransferase
activity		 F
IDA
SceS000004294
TAS
SceS000004294
SpoSPBC428.11
GO:0003962 cystathionine gamma-synthase activity F
IDA
AthAt3g01120
IMP
SceS000003891
ISS
AthAt3g01120
At1g33320
SceYLL058w
SpoSPBC15D4.09c
GO:0004121 cystathionine beta-lyase activity F
IMP
AthAt3g57050
SceS000003152
ISS
SceYHR112c
S000001952
S000003152
SpoSPCC11E10.01
GO:0004123 cystathionine gamma-lyase activity F
IDA
SceS000000010
IMP
SceS000000010
NAS
DmeFBgn0000566
TAS
DmeFBgn0000566
GO:0004124 cysteine synthase activity F
IDA
SceS000004294
ISS
SpoSPBC428.11
GO:0016829 lyase activity F
RCA
SceS000003891
GO:0016846 carbon-sulfur lyase activity F
ISS
SceYML082w
GO:0018826 methionine gamma-lyase activity F
IDA
AthAt1g64660
GO:0000096 sulfur amino acid metabolic process P
NAS
DmeFBgn0000566
TAS
SceS000000010
GO:0006082 organic acid metabolic process P
RCA
SceS000003891
GO:0006312 mitotic recombination P
IMP
SceS000001952
GO:0006414 translational elongation P
RCA
SceS000000010
S000001952
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000003891
S000000010
GO:0006520 cellular amino acid metabolic process P
ISS
AthAt1g64660
GO:0006534 cysteine metabolic process P
ISS
SpoSPBC15D4.09c
TAS
SceS000000010
GO:0006555 methionine metabolic process P
IMP
SceS000004294
ISS
SpoSPBC428.11
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000003891
GO:0006790 sulfur metabolic process P
IMP
SceS000003891
ISS
SceYLL058w
YHR112c
S000001952
YML082w
RCA
SceS000000010
S000003152
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000003891
S000000010
GO:0006878 cellular copper ion homeostasis P
IEP
SceS000001952
GO:0009086 methionine biosynthetic process P
IMP
AthAt3g01120
SceS000003152
ISS
AthAt1g33320
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00022856
GO:0019279 L-methionine biosynthetic process from
L-homoserine via cystathionine		 P
IC
SpoSPCC11E10.01
TAS
AthAt3g57050
GO:0019281 L-methionine biosynthetic process from homoserine
via O-succinyl-L-homoserine and
cystathionine		 P
ISS
SpoSPBC15D4.09c
GO:0019343 cysteine biosynthetic process via
cystathionine		 P
IMP
SceS000000010
GO:0019344 cysteine biosynthetic process P
IMP
SceS000000010
ISS
SpoSPBC428.11
TAS
SceS000004294
GO:0019346 transsulfuration P
IMP
SceS000000010
S000003891
S000003152
GO:0019458 methionine catabolic process via
2-oxobutanoate		 P
TAS
AthAt1g64660
GO:0046483 heterocycle metabolic process P
RCA
SceS000000010
S000003152

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6509

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC428.11 GI:19111981 O13326
Saccharomyces cerevisiae (Sce) MET17
(S000004294)		 GI:6323333 P06106
Kluyveromyces lactis (Kla) MT17_KLULA GI:50306539
Eremothecium gossypii (Ego) AGOS_ADL031W GI:45187843
Magnaporthe grisea (Mgr) MGG_07195 GI:39971759
Neurospora crassa (Ncr) NCU01652.1 GI:32415223
Oryza sativa (Osa) Os10g0399200 GI:115481892
Oryza sativa (Osa) Os10g0399700 GI:115481894


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000004294
GO:0005634 nucleus C
IDA
SpoSPBC428.11
GO:0005737 cytoplasm C
IDA
SceS000004294
ISS
SpoSPBC428.11
GO:0005829 cytosol C
IDA
SpoSPBC428.11
GO:0003961 O-acetylhomoserine aminocarboxypropyltransferase
activity		 F
IDA
SceS000004294
TAS
SceS000004294
SpoSPBC428.11
GO:0004124 cysteine synthase activity F
IDA
SceS000004294
ISS
SpoSPBC428.11
GO:0006555 methionine metabolic process P
IMP
SceS000004294
ISS
SpoSPBC428.11
GO:0019344 cysteine biosynthetic process P
ISS
SpoSPBC428.11
TAS
SceS000004294

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4999

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1711 ADL031W
Candida glabrata (Cgl) cgl928 CAGL0D06402g
Debaryomyces hansenii (Dha) dha4681 DEHA0F06644g
Kluyveromyces lactis (Kla) kla2242 KLLA0D04037g
Neurospora crassa (Ncr) ncr1606 NCU01652.2
Saccharomyces cerevisiae (Sce) sce4413 YLR303W
(S000004294)
Schizosaccharomyces pombe (Spo) spo1145 SPBC428.11 O13326
Yarrowia lipolytica (Yli) yli3763 YALI0D25168g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000004294
GO:0005634 nucleus C
IDA
SpoSPBC428.11
GO:0005737 cytoplasm C
IDA
SceS000004294
ISS
SpoSPBC428.11
GO:0005829 cytosol C
IDA
SpoSPBC428.11
GO:0003961 O-acetylhomoserine aminocarboxypropyltransferase
activity		 F
IDA
SceS000004294
TAS
SceS000004294
SpoSPBC428.11
GO:0004124 cysteine synthase activity F
IDA
SceS000004294
ISS
SpoSPBC428.11
GO:0006555 methionine metabolic process P
IMP
SceS000004294
ISS
SpoSPBC428.11
GO:0019344 cysteine biosynthetic process P
ISS
SpoSPBC428.11
TAS
SceS000004294

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC428.11
(O13326)		 YLR303W
(S000004294)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000004294
GO:0005634 nucleus C
IDA
SpoSPBC428.11
GO:0005737 cytoplasm C
IDA
SceS000004294
ISS
SpoSPBC428.11
GO:0005829 cytosol C
IDA
SpoSPBC428.11
GO:0003961 O-acetylhomoserine aminocarboxypropyltransferase
activity		 F
IDA
SceS000004294
TAS
SceS000004294
SpoSPBC428.11
GO:0004124 cysteine synthase activity F
IDA
SceS000004294
ISS
SpoSPBC428.11
GO:0006555 methionine metabolic process P
IMP
SceS000004294
ISS
SpoSPBC428.11
GO:0019344 cysteine biosynthetic process P
ISS
SpoSPBC428.11
TAS
SceS000004294

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