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Search term: YLR304C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ACO1
SGD link S000004295
Alternative ID YLR304C
Description Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy
Synonyms YLR304C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0453 -CDHYP-

KOGs classification KOGs description
METABOLISMMETABOLISM Aconitase/homoaconitase (aconitase superfamily)

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE25005
(WBGene00000041)		 GI:17553624
Drosophila melanogaster (Dme) 7298762 GI:7298762
Drosophila melanogaster (Dme) 7299398 GI:7299398
Homo sapiens (Hsa) Hs17450976 GI:17450976
Homo sapiens (Hsa) Hs17489116 GI:17489116
Homo sapiens (Hsa) Hs22051976 GI:22051976
Homo sapiens (Hsa) Hs22068703 GI:22068703
Homo sapiens (Hsa) Hs4501867
(ACO2)		 GI:4501867 Q71UF1
Saccharomyces cerevisiae (Sce) YDR234w
(S000002642)		 GI:6320440 P49367
Saccharomyces cerevisiae (Sce) YJL200c
(S000003736)		 GI:6322261 P39533
Saccharomyces cerevisiae (Sce) YLR304c
(S000004295)		 GI:6323335 P19414
Schizosaccharomyces pombe (Spo) SPAC24C9.06c GI:19114943 O13966
Schizosaccharomyces pombe (Spo) SPAC343.16 GI:19114349 Q9UT74
Schizosaccharomyces pombe (Spo) SPBP4H10.15 GI:19112981 Q9P7D4
Caenorhabditis elegans (Cel) CE25005
(WBGene00000041)		 GI:17553624
Drosophila melanogaster (Dme) 7298762 GI:7298762
Drosophila melanogaster (Dme) 7299398 GI:7299398
Homo sapiens (Hsa) Hs17450976 GI:17450976
Homo sapiens (Hsa) Hs17489116 GI:17489116
Homo sapiens (Hsa) Hs22051976 GI:22051976
Homo sapiens (Hsa) Hs22068703 GI:22068703
Homo sapiens (Hsa) Hs4501867
(ACO2)		 GI:4501867 Q71UF1
Saccharomyces cerevisiae (Sce) YDR234w
(S000002642)		 GI:6320440 P49367
Saccharomyces cerevisiae (Sce) YJL200c
(S000003736)		 GI:6322261 P39533
Saccharomyces cerevisiae (Sce) YLR304c
(S000004295)		 GI:6323335 P19414
Schizosaccharomyces pombe (Spo) SPAC24C9.06c GI:19114943 O13966
Schizosaccharomyces pombe (Spo) SPAC343.16 GI:19114349 Q9UT74
Schizosaccharomyces pombe (Spo) SPBP4H10.15 GI:19112981 Q9P7D4
Caenorhabditis elegans (Cel) CE25005
(WBGene00000041)		 GI:17553624
Drosophila melanogaster (Dme) 7298762 GI:7298762
Drosophila melanogaster (Dme) 7299398 GI:7299398
Homo sapiens (Hsa) Hs17450976 GI:17450976
Homo sapiens (Hsa) Hs17489116 GI:17489116
Homo sapiens (Hsa) Hs22051976 GI:22051976
Homo sapiens (Hsa) Hs22068703 GI:22068703
Homo sapiens (Hsa) Hs4501867
(ACO2)		 GI:4501867 Q71UF1
Saccharomyces cerevisiae (Sce) YDR234w
(S000002642)		 GI:6320440 P49367
Saccharomyces cerevisiae (Sce) YJL200c
(S000003736)		 GI:6322261 P39533
Saccharomyces cerevisiae (Sce) YLR304c
(S000004295)		 GI:6323335 P19414
Schizosaccharomyces pombe (Spo) SPAC24C9.06c GI:19114943 O13966
Schizosaccharomyces pombe (Spo) SPAC343.16 GI:19114349 Q9UT74
Schizosaccharomyces pombe (Spo) SPBP4H10.15 GI:19112981 Q9P7D4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaACO2
GO:0005739 mitochondrion C
IC
SpoSPBP4H10.15
IDA
HsaACO2
SceS000004295
S000003736
S000002642
SpoSPAC343.16
SPAC24C9.06c
SPBP4H10.15
IMP
SpoSPAC343.16
TAS
SceS000002642
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC24C9.06c
TAS
SceS000004295
GO:0005762 mitochondrial large ribosomal subunit C
ISS
SpoSPBP4H10.15
GO:0005829 cytosol C
ISS
SpoSPAC24C9.06c
TAS
SceS000004295
GO:0042645 mitochondrial nucleoid C
IDA
SceS000004295
GO:0003690 double-stranded DNA binding F
IDA
SceS000004295
GO:0003697 single-stranded DNA binding F
IDA
SceS000004295
GO:0003735 structural constituent of ribosome F
ISS
SpoSPBP4H10.15
GO:0003994 aconitate hydratase activity F
ISS
SceS000003736
SpoSPBP4H10.15
SPAC24C9.06c
TAS
SceS000004295
GO:0004409 homoaconitate hydratase activity F
IMP
SpoSPAC343.16
TAS
SceS000002642
GO:0005506 iron ion binding F
IDA
HsaACO2
GO:0000002 mitochondrial genome maintenance P
IMP
SceS000004295
GO:0000003 reproduction P
IMP
CelWBGene00000041
GO:0002119 nematode larval development P
IMP
CelWBGene00000041
GO:0006082 organic acid metabolic process P
RCA
SceS000003736
GO:0006091 generation of precursor metabolites and
energy		 P
NAS
SpoSPAC343.16
TAS
HsaACO2
GO:0006099 tricarboxylic acid cycle P
IDA
HsaACO2
ISS
SpoSPBP4H10.15
SPAC24C9.06c
TAS
SceS000004295
GO:0006101 citrate metabolic process P
IC
SpoSPBP4H10.15
IDA
HsaACO2
ISS
SpoSPAC24C9.06c
TAS
SceS000004295
GO:0006412 translation P
ISS
SpoSPBP4H10.15
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000003736
GO:0006536 glutamate metabolic process P
ISS
SpoSPAC24C9.06c
NAS
SpoSPAC343.16
SPBP4H10.15
GO:0006537 glutamate biosynthetic process P
TAS
SceS000004295
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000003736
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000003736
GO:0008150 biological_process P
ND
SceS000003736
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00000041
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000041
GO:0016246 RNA interference P
IMP
CelWBGene00000041
GO:0019541 propionate metabolic process P
IEP
SceS000004295
ISS
SpoSPAC24C9.06c
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SpoSPAC343.16
NAS
SceS000002642
GO:0032543 mitochondrial translation P
NAS
SpoSPBP4H10.15
GO:0040007 growth P
IMP
CelWBGene00000041
GO:0040011 locomotion P
IMP
CelWBGene00000041
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000041

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
856

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ACO2 GI:4501867 Q71UF1
Pan troglodytes (Ptr) ACO2 GI:114686100
Canis familiaris (Cfa) ACO2 GI:73968978
Mus musculus (Mmu) Aco2
(MGI:87880)		 GI:18079339 Q99KI0
Rattus norvegicus (Rno) Aco2
(RGD:621360)		 GI:40538860
Gallus gallus (Gga) ACO2 GI:45383738
Drosophila melanogaster (Dme) Acon
(FBgn0010100)		 GI:17864292
Anopheles gambiae (Aga) AgaP_AGAP007852 GI:158297404
Caenorhabditis elegans (Cel) aco-2
(CE25005;
WBGene00000041)		 GI:25149337
Schizosaccharomyces pombe (Spo) SPAC24C9.06c GI:19114943 O13966
Saccharomyces cerevisiae (Sce) ACO1
(S000004295)		 GI:6323335 P19414
Kluyveromyces lactis (Kla) KLLA0C17314g GI:50306025
Eremothecium gossypii (Ego) AGOS_ADL032W GI:45187842
Magnaporthe grisea (Mgr) MGG_03521 GI:39942882
Neurospora crassa (Ncr) NCU02366.1 GI:32421397


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaACO2
GO:0005739 mitochondrion C
IDA
HsaACO2
MmuMGI:87880
SceS000004295
SpoSPAC24C9.06c
ISO
MmuMGI:87880
ISS
DmeFBgn0010100
NAS
DmeFBgn0010100
GO:0005759 mitochondrial matrix C
ISS
SpoSPAC24C9.06c
TAS
SceS000004295
GO:0005811 lipid particle C
IDA
DmeFBgn0010100
GO:0005829 cytosol C
ISS
SpoSPAC24C9.06c
TAS
SceS000004295
GO:0042645 mitochondrial nucleoid C
IDA
SceS000004295
GO:0003690 double-stranded DNA binding F
IDA
SceS000004295
GO:0003697 single-stranded DNA binding F
IDA
SceS000004295
GO:0003994 aconitate hydratase activity F
IDA
MmuMGI:87880
ISO
MmuMGI:87880
ISS
DmeFBgn0010100
SpoSPAC24C9.06c
NAS
DmeFBgn0010100
TAS
SceS000004295
GO:0005506 iron ion binding F
IDA
HsaACO2
ISO
MmuMGI:87880
GO:0051538 3 iron, 4 sulfur cluster binding F
ISO
MmuMGI:87880
GO:0051539 4 iron, 4 sulfur cluster binding F
ISO
MmuMGI:87880
GO:0000002 mitochondrial genome maintenance P
IMP
SceS000004295
GO:0000003 reproduction P
IMP
CelWBGene00000041
GO:0002119 nematode larval development P
IMP
CelWBGene00000041
GO:0006091 generation of precursor metabolites and
energy		 P
TAS
HsaACO2
GO:0006099 tricarboxylic acid cycle P
IDA
HsaACO2
ISO
MmuMGI:87880
ISS
SpoSPAC24C9.06c
TAS
SceS000004295
GO:0006101 citrate metabolic process P
IDA
HsaACO2
ISO
MmuMGI:87880
ISS
SpoSPAC24C9.06c
TAS
SceS000004295
GO:0006102 isocitrate metabolic process P
ISO
MmuMGI:87880
GO:0006536 glutamate metabolic process P
ISS
SpoSPAC24C9.06c
GO:0006537 glutamate biosynthetic process P
TAS
SceS000004295
GO:0008152 metabolic process P
IDA
MmuMGI:87880
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00000041
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00000041
GO:0016246 RNA interference P
IMP
CelWBGene00000041
GO:0019541 propionate metabolic process P
IEP
SceS000004295
ISS
SpoSPAC24C9.06c
GO:0040007 growth P
IMP
CelWBGene00000041
GO:0040011 locomotion P
IMP
CelWBGene00000041
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000041

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2459

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9783 ENSANGP00000018525
Ashbya gossypii (Ago) ago1710 ADL032W
Caenorhabditis elegans (Cel) cel10291 F54H12.1a
(CE25005;
WBGene00000041)
Caenorhabditis elegans (Cel) cel10292 F54H12.1b
(CE30144)
Caenorhabditis elegans (Cel) cel10293 F54H12.1c
(CE32436)
Candida glabrata (Cgl) cgl929 CAGL0D06424g
Cryptococcus neoformans (Cne) cne614 163.m06211
Dictyostelium discoideum (Ddi) ddi12527 DDB0230168
Debaryomyces hansenii (Dha) dha3374 DEHA0E02948g
Drosophila melanogaster (Dme) dme11982 CG4706-PA
(FBgn0037862)
Drosophila melanogaster (Dme) dme3226 CG9244-PB
(FBgn0010100)
Danio rerio (Dre) dre3324 ENSDARP00000028117
(aco2)		 Q6PEI6
Danio rerio (Dre) dre9350 ENSDARP00000040200
Danio rerio (Dre) dre9349 ENSDARP00000041316
Escherichia coli (Eco) eco742 16128739
Takifugu rubripes (Fru) fru26224 SINFRUP00000149193
Takifugu rubripes (Fru) fru26223 SINFRUP00000176034
Gallus gallus (Gga) gga828 ENSGALP00000019468
(ACO2)		 Q5ZMW1
Homo sapiens (Hsa) hsa21743 ENSP00000216254
(ACO2)		 Q99798
Kluyveromyces lactis (Kla) kla1973 KLLA0C17314g
Mus musculus (Mmu) mmu9365 ENSMUSP00000023116
(MGI:87880)		 Q99KI0
Neurospora crassa (Ncr) ncr2299 NCU02366.2
Rattus norvegicus (Rno) rno27460 ENSRNOP00000029144
(RGD:621360)		 Q9ER34
Saccharomyces cerevisiae (Sce) sce4414 YLR304C
(S000004295)
Schizosaccharomyces pombe (Spo) spo4123 SPAC24C9.06c O13966
Yarrowia lipolytica (Yli) yli3100 YALI0D09361g