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Search term: YLR306W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name UBC12
SGD link S000004297
Alternative ID YLR306W
Description Enzyme that mediates the conjugation of Rub1p, a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes
Synonyms YLR306W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0420 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ubiquitin-protein ligase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g18600 GI:18398792
Arabidopsis thaliana (Ath) At4g36800 GI:15234531
Caenorhabditis elegans (Cel) CE16309
(WBGene00006707)
GI:17508589 Q9XVK5
Drosophila melanogaster (Dme) 7295143 GI:7295143
Homo sapiens (Hsa) Hs18087857
(UBE2F)
GI:18087857 Q969M7
Homo sapiens (Hsa) Hs4507791
(UBE2M)
GI:4507791 P61081
Saccharomyces cerevisiae (Sce) YLR306w
(S000004297)
GI:6323337 P52491
Schizosaccharomyces pombe (Spo) SPCC777.10c GI:19075756 O74549
Encephalitozoon cuniculi (Ecu) ECU10g1540 GI:19074764 Q8SR07
Arabidopsis thaliana (Ath) At2g18600 GI:18398792
Arabidopsis thaliana (Ath) At4g36800 GI:15234531
Caenorhabditis elegans (Cel) CE16309
(WBGene00006707)
GI:17508589 Q9XVK5
Drosophila melanogaster (Dme) 7295143 GI:7295143
Homo sapiens (Hsa) Hs18087857
(UBE2F)
GI:18087857 Q969M7
Homo sapiens (Hsa) Hs4507791
(UBE2M)
GI:4507791 P61081
Saccharomyces cerevisiae (Sce) YLR306w
(S000004297)
GI:6323337 P52491
Schizosaccharomyces pombe (Spo) SPCC777.10c GI:19075756 O74549
Encephalitozoon cuniculi (Ecu) ECU10g1540 GI:19074764 Q8SR07
Arabidopsis thaliana (Ath) At2g18600 GI:18398792
Arabidopsis thaliana (Ath) At4g36800 GI:15234531
Caenorhabditis elegans (Cel) CE16309
(WBGene00006707)
GI:17508589 Q9XVK5
Drosophila melanogaster (Dme) 7295143 GI:7295143
Homo sapiens (Hsa) Hs18087857
(UBE2F)
GI:18087857 Q969M7
Homo sapiens (Hsa) Hs4507791
(UBE2M)
GI:4507791 P61081
Saccharomyces cerevisiae (Sce) YLR306w
(S000004297)
GI:6323337 P52491
Schizosaccharomyces pombe (Spo) SPCC777.10c GI:19075756 O74549
Encephalitozoon cuniculi (Ecu) ECU10g1540 GI:19074764 Q8SR07


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g18600
At4g36800
HsaUBE2M
SceS000004297
GO:0005634 nucleus C
IDA
SpoSPCC777.10c
GO:0005829 cytosol C
IDA
SpoSPCC777.10c
GO:0004842 ubiquitin-protein ligase activity F
IMP
HsaUBE2M
ISS
AthAt2g18600
RCA
SceS000004297
TAS
HsaUBE2M
GO:0005515 protein binding F
IPI
HsaUBE2M
UBE2F
GO:0018169 ribosomal S6-glutamic acid ligase
activity
F
IDA
HsaUBE2M
GO:0019787 small conjugating protein ligase
activity
F
IDA
AthAt4g36800
ISS
AthAt2g18600
At4g36800
SpoSPCC777.10c
GO:0019788 NEDD8 ligase activity F
IC
SpoSPCC777.10c
IDA
HsaUBE2M
UBE2F
SceS000004297
IMP
SceS000004297
ISS
SceS000004297
TAS
AthAt4g36800
GO:0000003 reproduction P
IMP
CelWBGene00006707
GO:0000910 cytokinesis P
IMP
CelWBGene00006707
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00006707
GO:0006464 protein modification process P
IMP
HsaUBE2M
TAS
HsaUBE2M
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPCC777.10c
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00006707
GO:0009733 response to auxin stimulus P
IMP
AthAt4g36800
GO:0009790 embryo development P
IGI
AthAt4g36800
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00006707
GO:0016246 RNA interference P
IMP
CelWBGene00006707
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00006707
GO:0040011 locomotion P
IMP
CelWBGene00006707
GO:0040025 vulval development P
IMP
CelWBGene00006707
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00006707
GO:0045116 protein neddylation P
IDA
HsaUBE2M
UBE2F
SceS000004297
IMP
SceS000004297
ISS
SceS000004297
SpoSPCC777.10c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2952

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) UBE2M GI:4507791 P61081
Pan troglodytes (Ptr) UBE2M GI:114679462
Canis familiaris (Cfa) UBE2M GI:73947229
Mus musculus (Mmu) Ube2m
(MGI:108278)
GI:21704162 P61082
Rattus norvegicus (Rno) Ube2m GI:109458188
Drosophila melanogaster (Dme) CG7375
(FBgn0035853)
GI:24660710
Anopheles gambiae (Aga) AgaP_AGAP005916 GI:58387974
Schizosaccharomyces pombe (Spo) ubc12
(SPCC777.10c)
GI:19075756 O74549
Saccharomyces cerevisiae (Sce) UBC12
(S000004297)
GI:6323337 P52491
Kluyveromyces lactis (Kla) KLLA0C17248g GI:50306019
Eremothecium gossypii (Ego) AGOS_ADL035C GI:45187839
Magnaporthe grisea (Mgr) MGG_01807 GI:145613205
Neurospora crassa (Ncr) NCU03610.1 GI:32404598
Arabidopsis thaliana (Ath) AT2G18600 GI:18398792
Oryza sativa (Osa) Os08g0374100 GI:115476136
Oryza sativa (Osa) Os09g0321900 GI:115478528
Plasmodium falciparum (Pfa) PFL2175w GI:124806816


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g18600
DmeFBgn0035853
HsaUBE2M
PfaPFL2175w
SceS000004297
GO:0005634 nucleus C
IDA
SpoSPCC777.10c
GO:0005829 cytosol C
IDA
SpoSPCC777.10c
GO:0004842 ubiquitin-protein ligase activity F
IMP
HsaUBE2M
ISS
AthAt2g18600
DmeFBgn0035853
RCA
SceS000004297
TAS
HsaUBE2M
GO:0005515 protein binding F
IPI
HsaUBE2M
GO:0018169 ribosomal S6-glutamic acid ligase
activity
F
IDA
HsaUBE2M
GO:0019787 small conjugating protein ligase
activity
F
ISS
AthAt2g18600
SpoSPCC777.10c
GO:0019788 NEDD8 ligase activity F
IC
SpoSPCC777.10c
IDA
HsaUBE2M
SceS000004297
IMP
SceS000004297
ISS
SceS000004297
GO:0006464 protein modification process P
IMP
HsaUBE2M
TAS
HsaUBE2M
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPCC777.10c
GO:0043525 positive regulation of neuron apoptosis P
ISO
MmuMGI:108278
GO:0045116 protein neddylation P
IDA
HsaUBE2M
SceS000004297
IMP
SceS000004297
ISS
SceS000004297
SpoSPCC777.10c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1174

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga14264 ENSANGP00000013475
Anopheles gambiae (Aga) aga1358 ENSANGP00000013586
Anopheles gambiae (Aga) aga9385 ENSANGP00000022922
Ashbya gossypii (Ago) ago1707 ADL035C
Arabidopsis thaliana (Ath) ath8716 At2g18600.1
Caenorhabditis elegans (Cel) cel13649 R09B3.4
(CE16309;
WBGene00006707)
Candida glabrata (Cgl) cgl931 CAGL0D06468g
Cryptococcus neoformans (Cne) cne3863 185.m02449
Dictyostelium discoideum (Ddi) ddi6199 DDB0204633
Debaryomyces hansenii (Dha) dha2032 DEHA0C13651g
Drosophila melanogaster (Dme) dme8511 CG7375-PA
(FBgn0035853)
Danio rerio (Dre) dre31202 ENSDARP00000022874
Danio rerio (Dre) dre49 ENSDARP00000031623
Encephalitozoon cuniculi (Ecu) ecu680 19074764
Takifugu rubripes (Fru) fru2605 SINFRUP00000159413
Gallus gallus (Gga) gga21141 ENSGALP00000006035
(UBE2F)
Q5ZKX6
Homo sapiens (Hsa) hsa17313 ENSP00000253023
(UBE2M)
P61081
Homo sapiens (Hsa) hsa19536 ENSP00000272930
(UBE2F)
Q969M7-1
Kluyveromyces lactis (Kla) kla1970 KLLA0C17248g
Mus musculus (Mmu) mmu30915 ENSMUSP00000005714
(MGI:108278)
P61082
Mus musculus (Mmu) mmu774 ENSMUSP00000054007
Mus musculus (Mmu) mmu773 ENSMUSP00000054303
(MGI:1915171)
Q3V3M0
Mus musculus (Mmu) mmu775 ENSMUSP00000071225
Neurospora crassa (Ncr) ncr3501 NCU03610.2
Oryza sativa (Osa) osa26057 3909.m00156
Oryza sativa (Osa) osa42524 5195.m00112
Oryza sativa (Osa) osa42567 5195.m00188
Oryza sativa (Osa) osa50846 5923.m00131
Oryza sativa (Osa) osa50881 5923.m00168
Oryza sativa (Osa) osa72342 7055.m00116
Plasmodium falciparum (Pfa) pfa5216 PFL2175w
Rattus norvegicus (Rno) rno30467 ENSRNOP00000027050
(RGD:1307608)
Q5U203-1
Rattus norvegicus (Rno) rno1043 ENSRNOP00000034271
(RGD:1307614)
Saccharomyces cerevisiae (Sce) sce4416 YLR306W
(S000004297)
Schizosaccharomyces pombe (Spo) spo4499 SPCC777.10c O74549
Yarrowia lipolytica (Yli) yli3036 YALI0D07890g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g18600
DmeFBgn0035853
MmuMGI:1915171
PfaPFL2175w
SceS000004297
GO:0005634 nucleus C
IDA
SpoSPCC777.10c
GO:0005829 cytosol C
IDA
SpoSPCC777.10c
GO:0004842 ubiquitin-protein ligase activity F
ISS
AthAt2g18600
DmeFBgn0035853
RCA
SceS000004297
GO:0019787 small conjugating protein ligase
activity
F
ISS
AthAt2g18600
SpoSPCC777.10c
GO:0019788 NEDD8 ligase activity F
IC
SpoSPCC777.10c
IDA
SceS000004297
IMP
SceS000004297
ISS
SceS000004297
GO:0000003 reproduction P
IMP
CelWBGene00006707
GO:0000910 cytokinesis P
IMP
CelWBGene00006707
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00006707
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPCC777.10c
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00006707
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00006707
GO:0016246 RNA interference P
IMP
CelWBGene00006707
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00006707
GO:0040011 locomotion P
IMP
CelWBGene00006707
GO:0040025 vulval development P
IMP
CelWBGene00006707
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00006707
GO:0043525 positive regulation of neuron apoptosis P
ISO
MmuMGI:108278
GO:0045116 protein neddylation P
IDA
SceS000004297
IMP
SceS000004297
ISS
SceS000004297
SpoSPCC777.10c

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC777.10c
(O74549)
YLR306W
(S000004297)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004297
GO:0005634 nucleus C
IDA
SpoSPCC777.10c
GO:0005829 cytosol C
IDA
SpoSPCC777.10c
GO:0004842 ubiquitin-protein ligase activity F
RCA
SceS000004297
GO:0019787 small conjugating protein ligase
activity
F
ISS
SpoSPCC777.10c
GO:0019788 NEDD8 ligase activity F
IC
SpoSPCC777.10c
IDA
SceS000004297
IMP
SceS000004297
ISS
SceS000004297
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPCC777.10c
GO:0045116 protein neddylation P
IDA
SceS000004297
IMP
SceS000004297
ISS
SceS000004297
SpoSPCC777.10c

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GO info in one table:

s.khadayate@ucl.ac.uk