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Search term: YLR348C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DIC1
SGD link S000004340
Alternative ID YLR348C
Description Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
Synonyms YLR348C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0759 ACDHY--

KOGs classification KOGs description
METABOLISM Mitochondrial oxoglutarate/malate carrier proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g22500 GI:15227225
Arabidopsis thaliana (Ath) At4g24570 GI:15233884
Arabidopsis thaliana (Ath) At5g09470 GI:15242423
Arabidopsis thaliana (Ath) At5g19760 GI:15241167
Caenorhabditis elegans (Cel) CE02827
(WBGene00019656)		 GI:17568881 Q27322
Caenorhabditis elegans (Cel) CE07742 GI:17531323
Drosophila melanogaster (Dme) 7292529 GI:7292529
Drosophila melanogaster (Dme) 7292530 GI:7292530
Drosophila melanogaster (Dme) 7293873 GI:7293873
Drosophila melanogaster (Dme) 7293874 GI:7293874
Drosophila melanogaster (Dme) 7299149 GI:7299149 Q9VHG7
Drosophila melanogaster (Dme) 7299751 GI:5052494
Drosophila melanogaster (Dme) 7300617 GI:7300617
Drosophila melanogaster (Dme) 7301797 GI:7301797
Drosophila melanogaster (Dme) 7304116 GI:7304116
Homo sapiens (Hsa) Hs20149598
(SLC25A10)		 GI:20149598 Q9UBX3
Homo sapiens (Hsa) Hs21361114 GI:20141580 Q02978
Homo sapiens (Hsa) HsM4506997 GI:4506997
Saccharomyces cerevisiae (Sce) YLR348c
(S000004340)		 GI:6323381 Q06143
Arabidopsis thaliana (Ath) At2g22500 GI:15227225
Arabidopsis thaliana (Ath) At4g24570 GI:15233884
Arabidopsis thaliana (Ath) At5g09470 GI:15242423
Arabidopsis thaliana (Ath) At5g19760 GI:15241167
Caenorhabditis elegans (Cel) CE02827
(WBGene00019656)		 GI:17568881 Q27322
Caenorhabditis elegans (Cel) CE07742 GI:17531323
Drosophila melanogaster (Dme) 7292529 GI:7292529
Drosophila melanogaster (Dme) 7292530 GI:7292530
Drosophila melanogaster (Dme) 7293873 GI:7293873
Drosophila melanogaster (Dme) 7293874 GI:7293874
Drosophila melanogaster (Dme) 7299149 GI:7299149 Q9VHG7
Drosophila melanogaster (Dme) 7299751 GI:5052494
Drosophila melanogaster (Dme) 7300617 GI:7300617
Drosophila melanogaster (Dme) 7301797 GI:7301797
Drosophila melanogaster (Dme) 7304116 GI:7304116
Homo sapiens (Hsa) Hs20149598
(SLC25A10)		 GI:20149598 Q9UBX3
Homo sapiens (Hsa) Hs21361114 GI:20141580 Q02978
Homo sapiens (Hsa) HsM4506997 GI:4506997
Saccharomyces cerevisiae (Sce) YLR348c
(S000004340)		 GI:6323381 Q06143


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt5g19760
GO:0005739 mitochondrion C
IDA
AthAt5g19760
SceS000004340
GO:0005740 mitochondrial envelope C
IDA
SceS000004340
GO:0005743 mitochondrial inner membrane C
EXP
HsaSLC25A10
ISS
AthAt2g22500
At5g09470
At4g24570
At5g19760
GO:0005886 plasma membrane C
IDA
AthAt5g19760
GO:0009507 chloroplast C
IDA
AthAt5g19760
GO:0009941 chloroplast envelope C
IDA
AthAt5g19760
GO:0005310 dicarboxylic acid transmembrane transporter
activity		 F
EXP
HsaSLC25A10
IDA
AthAt5g09470
At4g24570
At2g22500
SceS000004340
GO:0005488 binding F
ISS
AthAt5g09470
At4g24570
At5g19760
At2g22500
GO:0005515 protein binding F
IPI
HsaSLC25A10
GO:0017077 oxidative phosphorylation uncoupler
activity		 F
ISS
AthAt5g09470
At5g19760
GO:0006094 gluconeogenesis P
TAS
HsaSLC25A10
GO:0006414 translational elongation P
RCA
SceS000004340
GO:0006810 transport P
ISS
AthAt5g09470
At4g24570
At5g19760
At2g22500
GO:0006835 dicarboxylic acid transport P
IDA
SceS000004340
TAS
HsaSLC25A10
GO:0006839 mitochondrial transport P
IDA
AthAt2g22500
At4g24570
At5g09470
ISS
AthAt4g24570
At5g19760
At5g09470
At2g22500

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6519

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SLC25A10 GI:20149598 Q9UBX3
Pan troglodytes (Ptr) SLC25A10 GI:114670955
Mus musculus (Mmu) Slc25a10
(MGI:1353497)		 GI:7305501 Q9QZD8
Rattus norvegicus (Rno) Slc25a10
(RGD:621430)		 GI:19173788
Gallus gallus (Gga) SLC25A10 GI:118099879
Drosophila melanogaster (Dme) CG8790
(FBgn0027610)		 GI:21357545
Anopheles gambiae (Aga) AgaP_AGAP003074 GI:158291225
Caenorhabditis elegans (Cel) K11G12.5
(CE02827;
WBGene00019656)		 GI:17568881 Q27322
Saccharomyces cerevisiae (Sce) DIC1
(S000004340)		 GI:6323381 Q06143
Magnaporthe grisea (Mgr) MGG_03216 GI:145608302
Neurospora crassa (Ncr) NCU01514.1 GI:32414947


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
MmuMGI:1353497
SceS000004340
ISS
DmeFBgn0027610
GO:0005740 mitochondrial envelope C
IDA
SceS000004340
ISS
DmeFBgn0027610
GO:0005743 mitochondrial inner membrane C
EXP
HsaSLC25A10
IDA
MmuMGI:1353497
GO:0005310 dicarboxylic acid transmembrane transporter
activity		 F
EXP
HsaSLC25A10
IDA
SceS000004340
ISS
DmeFBgn0027610
GO:0005515 protein binding F
IPI
HsaSLC25A10
GO:0015114 phosphate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015116 sulfate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015117 thiosulfate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015140 malate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015141 succinate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015291 secondary active transmembrane transporter
activity		 F
IDA
MmuMGI:1353497
GO:0015297 antiporter activity F
ISO
MmuMGI:1353497
GO:0022857 transmembrane transporter activity F
ISS
DmeFBgn0027610
GO:0006094 gluconeogenesis P
TAS
HsaSLC25A10
GO:0006414 translational elongation P
RCA
SceS000004340
GO:0006817 phosphate transport P
ISO
MmuMGI:1353497
GO:0006835 dicarboxylic acid transport P
IDA
SceS000004340
TAS
HsaSLC25A10
GO:0006839 mitochondrial transport P
ISA
MmuMGI:1353497
GO:0008272 sulfate transport P
ISO
MmuMGI:1353497
GO:0015709 thiosulfate transport P
ISO
MmuMGI:1353497
GO:0015743 malate transport P
ISO
MmuMGI:1353497
GO:0015744 succinate transport P
ISO
MmuMGI:1353497
GO:0055085 transmembrane transport P
IDA
MmuMGI:1353497

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_990

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9286 ENSANGP00000002250
Anopheles gambiae (Aga) aga5353 ENSANGP00000020409
Anopheles gambiae (Aga) aga5352 ENSANGP00000028024
Arabidopsis thaliana (Ath) ath9146 At2g22500.1
Arabidopsis thaliana (Ath) ath20425 At4g24570.1
Arabidopsis thaliana (Ath) ath23140 At5g09470.1
Arabidopsis thaliana (Ath) ath24249 At5g19760.1
Caenorhabditis elegans (Cel) cel486 B0432.4
(CE32102;
WBGene00015186)
Caenorhabditis elegans (Cel) cel12636 K11G12.5
(CE02827;
WBGene00019656)
Candida glabrata (Cgl) cgl1673 CAGL0G01166g
Cryptococcus neoformans (Cne) cne3902 185.m02490
Dictyostelium discoideum (Ddi) ddi8369 DDB0185907
Debaryomyces hansenii (Dha) dha4168 DEHA0E20933g
Drosophila melanogaster (Dme) dme8021 CG18418-PA
(FBgn0035568)
Drosophila melanogaster (Dme) dme15031 CG1907-PA
(FBgn0039674)
Drosophila melanogaster (Dme) dme8020 CG7514-PA
(FBgn0035567)
Drosophila melanogaster (Dme) dme12399 CG8790-PA
(FBgn0027610)
Drosophila melanogaster (Dme) dme12398 CG8790-PB
(FBgn0027610)
Danio rerio (Dre) dre17278 ENSDARP00000044299
Takifugu rubripes (Fru) fru22564 SINFRUP00000139879
Takifugu rubripes (Fru) fru19995 SINFRUP00000149184
Homo sapiens (Hsa) hsa12866 ENSP00000225665
(SLC25A11)		 Q02978
Homo sapiens (Hsa) hsa14520 ENSP00000328403
(SLC25A10)		 Q9UBX3-2
Homo sapiens (Hsa) hsa14519 ENSP00000345580
(SLC25A10)		 Q9UBX3-1
Mus musculus (Mmu) mmu4094 ENSMUSP00000014750
(MGI:1915113)		 Q9CR62
Mus musculus (Mmu) mmu5318 ENSMUSP00000026899
(MGI:1353497)		 Q9QZD8
Neurospora crassa (Ncr) ncr1469 NCU01514.2
Neurospora crassa (Ncr) ncr10302 NCU10732.2
Oryza sativa (Osa) osa16166 3067.m00116
Oryza sativa (Osa) osa17739 3317.m00075
Oryza sativa (Osa) osa22089 3692.m00224
Oryza sativa (Osa) osa41089 5251.m00153
Plasmodium falciparum (Pfa) pfa2125 PF08_0031
Rattus norvegicus (Rno) rno5419 ENSRNOP00000005144
(RGD:708476)		 P97700
Saccharomyces cerevisiae (Sce) sce4463 YLR348C
(S000004340)
Yarrowia lipolytica (Yli) yli885 YALI0B03344g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt5g19760
GO:0005739 mitochondrion C
IDA
AthAt5g19760
MmuMGI:1353497
MGI:1915113
SceS000004340
ISO
MmuMGI:1915113
ISS
DmeFBgn0027610
GO:0005740 mitochondrial envelope C
IDA
SceS000004340
ISS
DmeFBgn0027610
FBgn0039674
FBgn0035568
FBgn0035567
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1353497
MGI:1915113
ISS
AthAt2g22500
At5g09470
At4g24570
At5g19760
DmeFBgn0035568
FBgn0039674
FBgn0035567
PfaPF08_0031
GO:0005811 lipid particle C
IDA
DmeFBgn0039674
GO:0005886 plasma membrane C
IDA
AthAt5g19760
GO:0009507 chloroplast C
IDA
AthAt5g19760
GO:0009941 chloroplast envelope C
IDA
AthAt5g19760
GO:0005215 transporter activity F
ISO
MmuMGI:1915113
GO:0005310 dicarboxylic acid transmembrane transporter
activity		 F
IDA
AthAt5g09470
At4g24570
At2g22500
SceS000004340
ISS
DmeFBgn0027610
PfaPF08_0031
GO:0005488 binding F
ISS
AthAt5g09470
At4g24570
At5g19760
At2g22500
GO:0015114 phosphate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015116 sulfate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015117 thiosulfate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015140 malate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015141 succinate transmembrane transporter
activity		 F
ISO
MmuMGI:1353497
GO:0015291 secondary active transmembrane transporter
activity		 F
IDA
MmuMGI:1353497
GO:0015297 antiporter activity F
ISO
MmuMGI:1353497
GO:0015367 oxoglutarate:malate antiporter
activity		 F
ISS
DmeFBgn0039674
FBgn0035567
FBgn0035568
PfaPF08_0031
GO:0017077 oxidative phosphorylation uncoupler
activity		 F
ISS
AthAt5g09470
At5g19760
GO:0022857 transmembrane transporter activity F
ISS
DmeFBgn0035568
FBgn0027610
FBgn0039674
FBgn0035567
GO:0006414 translational elongation P
RCA
SceS000004340
GO:0006810 transport P
ISS
AthAt5g09470
At4g24570
At5g19760
At2g22500
GO:0006817 phosphate transport P
ISO
MmuMGI:1353497
GO:0006835 dicarboxylic acid transport P
IDA
SceS000004340
GO:0006839 mitochondrial transport P
IDA
AthAt2g22500
At4g24570
At5g09470
ISA
MmuMGI:1353497
ISS
AthAt4g24570
At5g19760
At5g09470
At2g22500
DmeFBgn0035568
FBgn0039674
FBgn0035567
PfaPF08_0031
GO:0008272 sulfate transport P
ISO
MmuMGI:1353497
GO:0015709 thiosulfate transport P
ISO
MmuMGI:1353497
GO:0015742 alpha-ketoglutarate transport P
ISS
DmeFBgn0039674
FBgn0035567
FBgn0035568
PfaPF08_0031
GO:0015743 malate transport P
ISO
MmuMGI:1353497
ISS
DmeFBgn0039674
FBgn0035568
FBgn0035567
PfaPF08_0031
GO:0015744 succinate transport P
ISO
MmuMGI:1353497
GO:0055085 transmembrane transport P
IDA
MmuMGI:1353497

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