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| KOG name | Phylogenetic pattern (and link to KOGs with this pattern) |
| KOG0198 | AC-HYP-![]() |
| KOGs classification | KOGs description |
| CELLULAR PROCESSES AND SIGNALING | MEKK and related serine/threonine protein kinases |
| HomoloGene cluster | Phylogenetic pattern |
| 56264 | ![]() |
| Species | Gene ID | NCBI link | UniProt link |
| Schizosaccharomyces pombe (Spo) | byr2 (SPBC1D7.05) | GI:19112506 | P28829 |
| Saccharomyces cerevisiae (Sce) | STE11 (S000004354) | GI:6323394 | P23561 |
| Kluyveromyces lactis (Kla) | KLLA0B13112g | GI:50304331 | |
| Eremothecium gossypii (Ego) | AGOS_ABL011C | GI:45185219 | |
| Magnaporthe grisea (Mgr) | MGG_12855 | GI:145608830 | |
| Neurospora crassa (Ncr) | NCU06182.1 | GI:32411113 |
| GO ID | GO term | GO aspect | Evidence codes and associations | ||||||||||||
| GO:0005737 | cytoplasm | C |
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| GO:0005886 | plasma membrane | C |
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| GO:0004709 | MAP kinase kinase kinase activity | F |
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| GO:0005515 | protein binding | F |
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| GO:0032093 | SAM domain binding | F |
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| GO:0000161 | MAPKKK cascade involved in osmosensory signaling pathway | P |
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| GO:0000165 | MAPKKK cascade | P |
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| GO:0000186 | activation of MAPKK activity | P |
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| GO:0000196 | MAPKKK cascade involved in cell wall biogenesis | P |
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| GO:0000746 | conjugation | P |
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| GO:0000750 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | P |
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| GO:0000751 | cell cycle arrest in response to pheromone | P |
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| GO:0001402 | signal transduction involved in filamentous growth | P |
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| GO:0001403 | invasive growth in response to glucose limitation | P |
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| GO:0006468 | protein amino acid phosphorylation | P |
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| GO:0007124 | pseudohyphal growth | P |
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| GO:0007166 | cell surface receptor linked signaling pathway | P |
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| GO:0007232 | osmosensory signaling pathway via Sho1 osmosensor | P |
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| GO:0009966 | regulation of signal transduction | P |
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| GO:0010525 | regulation of transposition, RNA-mediated | P |
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| GO:0019236 | response to pheromone | P |
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| GO:0019953 | sexual reproduction | P |
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| GO:0030447 | filamentous growth | P |
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| GO:0031142 | induction of conjugation upon nitrogen starvation | P |
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| GO:0032005 | regulation of conjugation with cellular fusion by signal transduction | P |
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| GO:0050790 | regulation of catalytic activity | P |
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| OrthoMCL cluster | Phylogenetic pattern |
| OG1_927 | ![]() |
| Species | OrthoMCL sequence | Model organism protein page | UniProt link |
| Ashbya gossypii (Ago) | ago581 | ABL011C | |
| Arabidopsis thaliana (Ath) | ath915 | At1g09000.1 | |
| Arabidopsis thaliana (Ath) | ath4655 | At1g53570.1 | |
| Arabidopsis thaliana (Ath) | ath4656 | At1g53570.2 | |
| Arabidopsis thaliana (Ath) | ath4817 | At1g54960.1 | |
| Arabidopsis thaliana (Ath) | ath12671 | At3g06030.1 | |
| Candida glabrata (Cgl) | cgl324 | CAGL0B02739g | |
| Cryptococcus neoformans (Cne) | cne927 | 163.m06364 | |
| Dictyostelium discoideum (Ddi) | ddi12318 | DDB0220118 | |
| Debaryomyces hansenii (Dha) | dha904 | DEHA0B04895g | |
| Danio rerio (Dre) | dre16075 | ENSDARP00000007519 | |
| Danio rerio (Dre) | dre20254 | ENSDARP00000015150 | |
| Danio rerio (Dre) | dre16076 | ENSDARP00000021037 | |
| Danio rerio (Dre) | dre20255 | ENSDARP00000025810 | |
| Danio rerio (Dre) | dre16074 | ENSDARP00000041994 | |
| Takifugu rubripes (Fru) | fru16764 | SINFRUP00000141140 | |
| Takifugu rubripes (Fru) | fru24149 | SINFRUP00000161599 | |
| Takifugu rubripes (Fru) | fru24148 | SINFRUP00000161603 | |
| Takifugu rubripes (Fru) | fru7998 | SINFRUP00000175270 | |
| Gallus gallus (Gga) | gga13719 | ENSGALP00000000722 | |
| Gallus gallus (Gga) | gga13720 | ENSGALP00000000723 (MAP3K3) | |
| Gallus gallus (Gga) | gga13721 | ENSGALP00000000724 | |
| Gallus gallus (Gga) | gga9351 | ENSGALP00000009443 (RCJMB04_4j19) | Q5ZLW4 |
| Gallus gallus (Gga) | gga9352 | ENSGALP00000009444 | |
| Gallus gallus (Gga) | gga9350 | ENSGALP00000009445 | |
| Gallus gallus (Gga) | gga21786 | ENSGALP00000018718 (MAP3K2) | |
| Gallus gallus (Gga) | gga21787 | ENSGALP00000018719 (MAP3K2) | |
| Homo sapiens (Hsa) | hsa18553 | ENSP00000343463 (MAP3K2) | Q9Y2U5 |
| Homo sapiens (Hsa) | hsa14146 | ENSP00000354485 (MAP3K3) | Q99759-1 |
| Homo sapiens (Hsa) | hsa18554 | ENSP00000354595 | |
| Homo sapiens (Hsa) | hsa14145 | ENSP00000354927 (MAP3K3) | Q99759-2 |
| Kluyveromyces lactis (Kla) | kla1113 | KLLA0B13112g | |
| Mus musculus (Mmu) | mmu4998 | ENSMUSP00000002044 (MGI:1346874) | Q61084 |
| Mus musculus (Mmu) | mmu12456 | ENSMUSP00000025242 (MGI:1346873) | Q61083 |
| Neurospora crassa (Ncr) | ncr6007 | NCU06182.2 | |
| Oryza sativa (Osa) | osa6185 | 2441.m00104 | |
| Oryza sativa (Osa) | osa6036 | 2469.m00150 | |
| Oryza sativa (Osa) | osa6938 | 2488.m00124 | |
| Oryza sativa (Osa) | osa38225 | 4888.m00129 | |
| Oryza sativa (Osa) | osa38248 | 4888.m00171 | |
| Oryza sativa (Osa) | osa36099 | 4923.m00139 | |
| Oryza sativa (Osa) | osa44324 | 5590.m00126 | |
| Oryza sativa (Osa) | osa44343 | 5590.m00164 | |
| Oryza sativa (Osa) | osa66768 | 6936.m00131 | |
| Rattus norvegicus (Rno) | rno6297 | ENSRNOP00000011406 (RGD:1304575) | B5DF98 |
| Rattus norvegicus (Rno) | rno13902 | ENSRNOP00000018975 | |
| Saccharomyces cerevisiae (Sce) | sce4478 | YLR362W (S000004354) | |
| Schizosaccharomyces pombe (Spo) | spo4671 | SPBC1D7.05 | P28829 |
| Yarrowia lipolytica (Yli) | yli5917 | YALI0F13629g |
| GO ID | GO term | GO aspect | Evidence codes and associations | ||||||||||||||||
| GO:0005575 | cellular_component | C |
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| GO:0005634 | nucleus | C |
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| GO:0005737 | cytoplasm | C |
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| GO:0005829 | cytosol | C |
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| GO:0005886 | plasma membrane | C |
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| GO:0048046 | apoplast | C |
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| GO:0004672 | protein kinase activity | F |
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| GO:0004709 | MAP kinase kinase kinase activity | F |
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| GO:0005515 | protein binding | F |
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| GO:0016301 | kinase activity | F |
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| GO:0032093 | SAM domain binding | F |
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| GO:0000161 | MAPKKK cascade involved in osmosensory signaling pathway | P |
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| GO:0000165 | MAPKKK cascade | P |
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| GO:0000186 | activation of MAPKK activity | P |
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| GO:0000196 | MAPKKK cascade involved in cell wall biogenesis | P |
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| GO:0000746 | conjugation | P |
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| GO:0000750 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | P |
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| GO:0000751 | cell cycle arrest in response to pheromone | P |
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| GO:0000910 | cytokinesis | P |
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| GO:0001402 | signal transduction involved in filamentous growth | P |
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| GO:0001403 | invasive growth in response to glucose limitation | P |
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| GO:0006468 | protein amino acid phosphorylation | P |
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| GO:0006979 | response to oxidative stress | P |
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| GO:0007124 | pseudohyphal growth | P |
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| GO:0007166 | cell surface receptor linked signaling pathway | P |
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| GO:0007232 | osmosensory signaling pathway via Sho1 osmosensor | P |
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| GO:0007243 | intracellular protein kinase cascade | P |
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| GO:0009908 | flower development | P |
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| GO:0009966 | regulation of signal transduction | P |
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| GO:0010525 | regulation of transposition, RNA-mediated | P |
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| GO:0016310 | phosphorylation | P |
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| GO:0019236 | response to pheromone | P |
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| GO:0019953 | sexual reproduction | P |
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| GO:0030447 | filamentous growth | P |
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| GO:0031142 | induction of conjugation upon nitrogen starvation | P |
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| GO:0032005 | regulation of conjugation with cellular fusion by signal transduction | P |
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| GO:0043622 | cortical microtubule organization | P |
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| GO:0046777 | protein amino acid autophosphorylation | P |
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| GO:0050790 | regulation of catalytic activity | P |
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Curated yeast ortholog results:
| S. pombe systematic ID | S. cerevisiae systematic ID |
| SPBC1D7.05 (P28829) | YLR362W (S000004354) |
| GO ID | GO term | GO aspect | Evidence codes and associations | ||||||||||||
| GO:0005737 | cytoplasm | C |
| ||||||||||||
| GO:0005886 | plasma membrane | C |
| ||||||||||||
| GO:0004709 | MAP kinase kinase kinase activity | F |
| ||||||||||||
| GO:0005515 | protein binding | F |
| ||||||||||||
| GO:0032093 | SAM domain binding | F |
| ||||||||||||
| GO:0000161 | MAPKKK cascade involved in osmosensory signaling pathway | P |
| ||||||||||||
| GO:0000165 | MAPKKK cascade | P |
| ||||||||||||
| GO:0000186 | activation of MAPKK activity | P |
| ||||||||||||
| GO:0000196 | MAPKKK cascade involved in cell wall biogenesis | P |
| ||||||||||||
| GO:0000746 | conjugation | P |
| ||||||||||||
| GO:0000750 | pheromone-dependent signal transduction involved in conjugation with cellular fusion | P |
| ||||||||||||
| GO:0000751 | cell cycle arrest in response to pheromone | P |
| ||||||||||||
| GO:0001402 | signal transduction involved in filamentous growth | P |
| ||||||||||||
| GO:0001403 | invasive growth in response to glucose limitation | P |
| ||||||||||||
| GO:0006468 | protein amino acid phosphorylation | P |
| ||||||||||||
| GO:0007124 | pseudohyphal growth | P |
| ||||||||||||
| GO:0007166 | cell surface receptor linked signaling pathway | P |
| ||||||||||||
| GO:0007232 | osmosensory signaling pathway via Sho1 osmosensor | P |
| ||||||||||||
| GO:0009966 | regulation of signal transduction | P |
| ||||||||||||
| GO:0010525 | regulation of transposition, RNA-mediated | P |
| ||||||||||||
| GO:0019236 | response to pheromone | P |
| ||||||||||||
| GO:0019953 | sexual reproduction | P |
| ||||||||||||
| GO:0030447 | filamentous growth | P |
| ||||||||||||
| GO:0031142 | induction of conjugation upon nitrogen starvation | P |
| ||||||||||||
| GO:0032005 | regulation of conjugation with cellular fusion by signal transduction | P |
| ||||||||||||
| GO:0050790 | regulation of catalytic activity | P |
|
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