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Search term: YLR372W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SUR4
SGD link S000004364
Alternative ID YLR372W
Description Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis
Synonyms YLR372W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3071 A-DHYP-

KOGs classification KOGs description
METABOLISM Fatty acyl-CoA elongase/Polyunsaturated fatty acid specific elongation enzyme

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g75000 GI:15222085
Arabidopsis thaliana (Ath) At3g06460 GI:15230725
Arabidopsis thaliana (Ath) At3g06470 GI:15230729
Arabidopsis thaliana (Ath) At4g36830 GI:15234538
Drosophila melanogaster (Dme) 7294765 GI:7294765
Drosophila melanogaster (Dme) 7294766 GI:7294766
Drosophila melanogaster (Dme) 7296847 GI:7296847
Drosophila melanogaster (Dme) 7298969 GI:7298969
Drosophila melanogaster (Dme) 7299264 GI:7299264 Q9VH59
Drosophila melanogaster (Dme) 7299265 GI:7299265
Drosophila melanogaster (Dme) 7299266 GI:7299266
Drosophila melanogaster (Dme) 7299267 GI:7299267
Drosophila melanogaster (Dme) 7299268 GI:7299268
Drosophila melanogaster (Dme) 7300874 GI:7300874
Drosophila melanogaster (Dme) 7300877 GI:7300877 Q9VCY7
Drosophila melanogaster (Dme) 7300878 GI:7300878 Q9VCY6
Drosophila melanogaster (Dme) 7300879 GI:7300879
Drosophila melanogaster (Dme) 7300880 GI:7300880
Drosophila melanogaster (Dme) 7300933 GI:7300933 Q9VCT3
Drosophila melanogaster (Dme) 7302564 GI:20130133
Drosophila melanogaster (Dme) 7302565 GI:7302565
Drosophila melanogaster (Dme) 7303830 GI:7303830
Homo sapiens (Hsa) Hs11464975
(ELOVL5)		 GI:11464975 Q9NYP7
Homo sapiens (Hsa) Hs12232379
(ELOVL4)		 GI:12232379 Q9GZR5
Homo sapiens (Hsa) Hs13489093
(ELOVL1)		 GI:13489093 Q9BW60
Homo sapiens (Hsa) Hs18561450 GI:18561450
Homo sapiens (Hsa) Hs8923312 GI:8923312
Homo sapiens (Hsa) HsM7705799 GI:7705799
Saccharomyces cerevisiae (Sce) YCR034w
(S000000630)		 GI:6319882 P25358
Saccharomyces cerevisiae (Sce) YJL196c
(S000003732)		 GI:6322265 P39540
Saccharomyces cerevisiae (Sce) YLR372w
(S000004364)		 GI:6323404 P40319
Schizosaccharomyces pombe (Spo) SPAC1B2.03c GI:19114842 Q9UTF7
Schizosaccharomyces pombe (Spo) SPAC806.09c GI:19113771


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaELOVL4
GO:0005783 endoplasmic reticulum C
IDA
SceS000000630
S000004364
SpoSPAC1B2.03c
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC1B2.03c
TAS
SceS000000630
GO:0016020 membrane C
ISS
SceS000003732
GO:0016021 integral to membrane C
ISS
AthAt3g06470
At4g36830
At3g06460
At1g75000
GO:0003674 molecular_function F
ND
AthAt3g06470
At4g36830
At3g06460
At1g75000
GO:0005515 protein binding F
IPI
HsaELOVL1
GO:0008020 G-protein coupled photoreceptor
activity		 F
NAS
HsaELOVL4
GO:0009922 fatty acid elongase activity F
IMP
SceS000003732
S000000630
S000004364
ISS
SpoSPAC1B2.03c
TAS
SceS000000630
GO:0006633 fatty acid biosynthetic process P
IMP
SceS000004364
NAS
HsaELOVL4
GO:0006892 post-Golgi vesicle-mediated transport P
IGI
SceS000004364
GO:0008150 biological_process P
ND
AthAt1g75000
At4g36830
At3g06470
At3g06460
GO:0016192 vesicle-mediated transport P
IMP
SceS000000630
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000630
S000004364
GO:0019368 fatty acid elongation, unsaturated fatty
acid		 P
IMP
SceS000003732
ISS
SpoSPAC1B2.03c
GO:0030148 sphingolipid biosynthetic process P
IMP
SceS000000630
S000004364
ISS
SpoSPAC1B2.03c
GO:0030497 fatty acid elongation P
IMP
SceS000004364
S000000630

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
81785

Species Gene ID NCBI link UniProt link
Caenorhabditis elegans (Cel) elo-1
(CE05979;
WBGene00001239)		 GI:17540774 Q20901
Caenorhabditis elegans (Cel) elo-5
(CE10284;
WBGene00001243)		 GI:17540336 Q20300
Caenorhabditis elegans (Cel) elo-6
(CE10286;
WBGene00001244)		 GI:17540338 Q20303
Caenorhabditis elegans (Cel) elo-7
(CE35559;
WBGene00001245)		 GI:71989832
Saccharomyces cerevisiae (Sce) SUR4
(S000004364)		 GI:6323404 P40319
Kluyveromyces lactis (Kla) KLLA0B07777g GI:50303859
Eremothecium gossypii (Ego) AGOS_AFR586W GI:45199104


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000004364
GO:0009922 fatty acid elongase activity F
IMP
SceS000004364
GO:0006633 fatty acid biosynthetic process P
IMP
SceS000004364
GO:0006636 unsaturated fatty acid biosynthetic
process		 P
IMP
CelWBGene00001239
GO:0006892 post-Golgi vesicle-mediated transport P
IGI
SceS000004364
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00001243
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004364
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00001243
GO:0030148 sphingolipid biosynthetic process P
IMP
SceS000004364
GO:0030497 fatty acid elongation P
IMP
SceS000004364
GO:0040007 growth P
IMP
CelWBGene00001243
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001243
WBGene00001244

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_212

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga2592 ENSANGP00000007555
Anopheles gambiae (Aga) aga1976 ENSANGP00000010068
Anopheles gambiae (Aga) aga10832 ENSANGP00000012448
Anopheles gambiae (Aga) aga9003 ENSANGP00000021118
Anopheles gambiae (Aga) aga3168 ENSANGP00000022632
Ashbya gossypii (Ago) ago3778 AFR586W
Ashbya gossypii (Ago) ago3816 AFR624W
Arabidopsis thaliana (Ath) ath12722 At3g06460.1
Arabidopsis thaliana (Ath) ath12723 At3g06470.1
Caenorhabditis elegans (Cel) cel3800 C40H1.4
(CE00112;
WBGene00001242)
Caenorhabditis elegans (Cel) cel5076 D2024.3
(CE34783;
WBGene00001241)
Caenorhabditis elegans (Cel) cel6054 F11E6.5
(CE19785;
WBGene00001240)
Caenorhabditis elegans (Cel) cel8851 F41H10.8
(CE10286;
WBGene00001244)
Caenorhabditis elegans (Cel) cel10665 F56H11.3
(CE35559;
WBGene00001245)
Caenorhabditis elegans (Cel) cel10666 F56H11.4
(CE05979;
WBGene00001239)
Candida glabrata (Cgl) cgl1832 CAGL0G04851g
Candida glabrata (Cgl) cgl4436 CAGL0L08184g
Cryptococcus neoformans (Cne) cne5167 179.m00013
Dictyostelium discoideum (Ddi) ddi2780 DDB0168618
Dictyostelium discoideum (Ddi) ddi5599 DDB0169275
Dictyostelium discoideum (Ddi) ddi10337 DDB0191679
Dictyostelium discoideum (Ddi) ddi2277 DDB0203216
Dictyostelium discoideum (Ddi) ddi12763 DDB0214890
Debaryomyces hansenii (Dha) dha5972 DEHA0G06116g
Debaryomyces hansenii (Dha) dha6183 DEHA0G10912g
Drosophila melanogaster (Dme) dme13878 CG33110-PA
(FBgn0053110)
Drosophila melanogaster (Dme) dme9853 CG3971-PA
(FBgn0036650)
Drosophila melanogaster (Dme) dme9854 CG3971-PB
(FBgn0036650)
Drosophila melanogaster (Dme) dme13935 CG6660-PA
(FBgn0039030)
Drosophila melanogaster (Dme) dme13875 CG6921-PA
(FBgn0038985)
Drosophila melanogaster (Dme) dme13874 CG6921-PB
(FBgn0038985)
Drosophila melanogaster (Dme) dme13876 CG6921-PC
(FBgn0038985)
Danio rerio (Dre) dre25798 ENSDARP00000015023
Danio rerio (Dre) dre1280 ENSDARP00000016309
(zgc:92749)		 Q503U9
Danio rerio (Dre) dre3386 ENSDARP00000027516
(elovl5)		 Q8AX86
Takifugu rubripes (Fru) fru30081 SINFRUP00000132732
Takifugu rubripes (Fru) fru24028 SINFRUP00000158121
Takifugu rubripes (Fru) fru27396 SINFRUP00000160508
Takifugu rubripes (Fru) fru25034 SINFRUP00000164405
Gallus gallus (Gga) gga20524 ENSGALP00000008983
(ELOVL3)
Gallus gallus (Gga) gga17925 ENSGALP00000019792
(RCJMB04_16d24)		 Q5ZJR8
Gallus gallus (Gga) gga10473 ENSGALP00000020774
(ELOVL2)
Gallus gallus (Gga) gga15760 ENSGALP00000025545
Gallus gallus (Gga) gga15881 ENSGALP00000026271
(ELOVL5)
Homo sapiens (Hsa) hsa4518 ENSP00000238970
Homo sapiens (Hsa) hsa24528 ENSP00000304736
(ELOVL6)		 Q9H5J4
Homo sapiens (Hsa) hsa27317 ENSP00000306640
(ELOVL5)		 Q9NYP7
Homo sapiens (Hsa) hsa26445 ENSP00000346693
(ELOVL2)		 Q9NXB9
Kluyveromyces lactis (Kla) kla874 KLLA0B07777g
Kluyveromyces lactis (Kla) kla1353 KLLA0C03542g
Mus musculus (Mmu) mmu6877 ENSMUSP00000021793
(MGI:1858960)		 Q9JLJ4
Mus musculus (Mmu) mmu27965 ENSMUSP00000034904
(MGI:1916051)		 Q8BHI7
Mus musculus (Mmu) mmu13841 ENSMUSP00000036357
(MGI:1195976)		 O35949
Mus musculus (Mmu) mmu17544 ENSMUSP00000071351
(MGI:2156528)		 Q920L5
Mus musculus (Mmu) mmu17545 ENSMUSP00000072692
Neurospora crassa (Ncr) ncr6510 NCU06694.2
Oryza sativa (Osa) osa18758 3216.m00161
Oryza sativa (Osa) osa20339 3540.m00100
Oryza sativa (Osa) osa87445 9233.m00075
Plasmodium falciparum (Pfa) pfa2601 PFA0455c
Rattus norvegicus (Rno) rno28960 ENSRNOP00000010409
(RGD:620583)		 Q920L7
Rattus norvegicus (Rno) rno17001 ENSRNOP00000014155
(RGD:620585)		 Q920L6
Rattus norvegicus (Rno) rno13172 ENSRNOP00000019756
(RGD:1308605)
Rattus norvegicus (Rno) rno4202 ENSRNOP00000025938
(RGD:1307263)
Saccharomyces cerevisiae (Sce) sce692 YCR034W
(S000000630)
Saccharomyces cerevisiae (Sce) sce3461 YJL196C
(S000003732)
Saccharomyces cerevisiae (Sce) sce4490 YLR372W
(S000004364)
Schizosaccharomyces pombe (Spo) spo2313 SPAC1639.01c Q7LKX0
Schizosaccharomyces pombe (Spo) spo3230 SPAC1B2.03c Q9UTF7
Yarrowia lipolytica (Yli) yli1580 YALI0B20196g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1639.01c
GO:0005783 endoplasmic reticulum C
IDA
SceS000000630
S000004364
SpoSPAC1B2.03c
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC1B2.03c
SPAC1639.01c
TAS
SceS000000630
GO:0005792 microsome C
IDA
MmuMGI:1858960
GO:0005829 cytosol C
IDA
SpoSPAC1639.01c
GO:0005886 plasma membrane C
ISS
PfaPFA0455c
GO:0016020 membrane C
ISS
SceS000003732
GO:0016021 integral to membrane C
ISS
AthAt3g06470
At3g06460
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IDA
MmuMGI:2156528
GO:0003674 molecular_function F
ND
AthAt3g06470
At3g06460
GO:0009922 fatty acid elongase activity F
IMP
SceS000003732
S000000630
S000004364
ISS
SpoSPAC1639.01c
SPAC1B2.03c
TAS
SceS000000630
GO:0016747 transferase activity, transferring acyl groups
other than amino-acyl groups		 F
IDA
MmuMGI:2156528
MGI:1858960
GO:0000003 reproduction P
IMP
CelWBGene00001240
GO:0000038 very long-chain fatty acid metabolic
process		 P
IDA
MmuMGI:1858960
ISS
DmeFBgn0053110
GO:0006629 lipid metabolic process P
IMP
CelWBGene00001240
GO:0006633 fatty acid biosynthetic process P
IMP
SceS000004364
ISS
DmeFBgn0053110
GO:0006636 unsaturated fatty acid biosynthetic
process		 P
IMP
CelWBGene00001239
GO:0006892 post-Golgi vesicle-mediated transport P
IGI
SceS000004364
GO:0008150 biological_process P
ND
AthAt3g06470
At3g06460
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00001240
GO:0010468 regulation of gene expression P
IMP
CelWBGene00001240
GO:0016192 vesicle-mediated transport P
IMP
SceS000000630
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000000630
S000004364
GO:0019368 fatty acid elongation, unsaturated fatty
acid		 P
IMP
SceS000003732
ISS
SpoSPAC1B2.03c
SPAC1639.01c
GO:0019915 lipid storage P
IMP
CelWBGene00001240
GO:0030148 sphingolipid biosynthetic process P
IMP
SceS000000630
S000004364
ISS
SpoSPAC1B2.03c
SPAC1639.01c
GO:0030497 fatty acid elongation P
IDA
MmuMGI:2156528
IMP
SceS000004364
S000000630
GO:0035264 multicellular organism growth P
IMP
CelWBGene00001240
GO:0040007 growth P
IMP
CelWBGene00001240
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001244
WBGene00001241
WBGene00001240

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1B2.03c
(Q9UTF7)		 YLR372W
(S000004364)
SPAC1639.01c
(Q7LKX0)		 YLR372W
(S000004364)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC1639.01c
GO:0005783 endoplasmic reticulum C
IDA
SceS000004364
SpoSPAC1B2.03c
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC1B2.03c
SPAC1639.01c
GO:0005829 cytosol C
IDA
SpoSPAC1639.01c
GO:0009922 fatty acid elongase activity F
IMP
SceS000004364
ISS
SpoSPAC1639.01c
SPAC1B2.03c
GO:0006633 fatty acid biosynthetic process P
IMP
SceS000004364
GO:0006892 post-Golgi vesicle-mediated transport P
IGI
SceS000004364
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004364
GO:0019368 fatty acid elongation, unsaturated fatty
acid		 P
ISS
SpoSPAC1B2.03c
SPAC1639.01c
GO:0030148 sphingolipid biosynthetic process P
IMP
SceS000004364
ISS
SpoSPAC1B2.03c
SPAC1639.01c
GO:0030497 fatty acid elongation P
IMP
SceS000004364

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