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Search term: YLR380W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CSR1
SGD link S000004372
Alternative ID YLR380W
Description Phosphatidylinositol transfer protein with a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance
Synonyms YLR380W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1470 A---YP-

KOGs classification KOGs description
METABOLISM Phosphatidylinositol transfer protein PDR16 and related proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g01630 GI:15223439
Arabidopsis thaliana (Ath) At1g05370 GI:15220495
Arabidopsis thaliana (Ath) At1g14820 GI:15223912
Arabidopsis thaliana (Ath) At1g22180 GI:15219230
Arabidopsis thaliana (Ath) At1g75170 GI:15222153
Arabidopsis thaliana (Ath) At3g22410 GI:15228742
Arabidopsis thaliana (Ath) At4g08690 GI:15236573
Arabidopsis thaliana (Ath) At4g36640 GI:15234469
Arabidopsis thaliana (Ath) At5g04780_2 GI:15238326
Arabidopsis thaliana (Ath) At5g63060 GI:15242621
Saccharomyces cerevisiae (Sce) YLR380w
(S000004372)		 GI:6323412 Q06705
Saccharomyces cerevisiae (Sce) YNL231c
(S000005175)		 GI:6324098 P53860
Saccharomyces cerevisiae (Sce) YNL264c
(S000005208)		 GI:6324065 P53844
Schizosaccharomyces pombe (Spo) SPAC3H8.02 GI:19113907 Q10138
Schizosaccharomyces pombe (Spo) SPAC589.09 GI:19114969 Q9HDZ5
Schizosaccharomyces pombe (Spo) SPBC365.01 GI:19112822 Q9UUC2
Schizosaccharomyces pombe (Spo) SPCC23B6.04c_2 GI:19075627 Q9UU99


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000005175
GO:0005575 cellular_component C
ND
AthAt1g14820
At3g22410
At1g22180
At1g05370
At1g01630
SpoSPCC23B6.04c
GO:0005634 nucleus C
IDA
SpoSPBC365.01
GO:0005737 cytoplasm C
IDA
SceS000005208
S000004372
S000005175
ISS
SpoSPAC589.09
SPAC3H8.02
SPBC365.01
GO:0005739 mitochondrion C
IDA
SceS000004372
SpoSPAC589.09
GO:0005768 endosome C
IDA
SceS000005208
GO:0005792 microsome C
IDA
SceS000005175
S000004372
GO:0005811 lipid particle C
IDA
SceS000005175
S000004372
GO:0005829 cytosol C
IDA
SceS000004372
SpoSPBC365.01
GO:0009507 chloroplast C
IDA
AthAt5g04780
At5g63060
GO:0032153 cell division site C
IDA
SpoSPBC365.01
GO:0051286 cell tip C
IDA
SpoSPBC365.01
GO:0003674 molecular_function F
ND
AthAt3g22410
At1g22180
At1g05370
GO:0005215 transporter activity F
ISS
AthAt1g75170
At1g14820
At4g08690
At5g63060
At4g36640
At1g01630
GO:0008525 phosphatidylcholine transmembrane transporter
activity		 F
ISS
SpoSPBC365.01
SPAC589.09
GO:0008526 phosphatidylinositol transporter
activity		 F
IDA
SceS000004372
S000005175
S000005208
ISS
SpoSPBC365.01
SPCC23B6.04c
SPAC3H8.02
SPAC589.09
GO:0006810 transport P
ISS
AthAt1g14820
At5g63060
At1g75170
At4g08690
At4g36640
At1g01630
GO:0007047 cellular cell wall organization P
ISS
SpoSPAC3H8.02
SPAC589.09
SPBC365.01
GO:0008150 biological_process P
ND
AthAt1g22180
At5g04780
At1g05370
At3g22410
GO:0008654 phospholipid biosynthetic process P
IMP
SceS000005208
GO:0015914 phospholipid transport P
IDA
SceS000005175
S000004372
S000005208
ISS
SpoSPCC23B6.04c
SPAC589.09
SPAC3H8.02
SPBC365.01
GO:0016126 sterol biosynthetic process P
IMP
SceS000005175
ISS
SpoSPCC23B6.04c
GO:0019217 regulation of fatty acid metabolic
process		 P
IGI
SceS000004372
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000004372
GO:0031505 fungal-type cell wall organization P
IGI
SceS000004372
GO:0042493 response to drug P
IGI
SceS000005175
S000005208

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31808

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC3H8.02 GI:19113907 Q10138
Saccharomyces cerevisiae (Sce) CSR1
(S000004372)		 GI:6323412 Q06705
Kluyveromyces lactis (Kla) KLLA0E05313g GI:50308371
Eremothecium gossypii (Ego) AGOS_AER041W GI:45190647
Magnaporthe grisea (Mgr) MGG_00871 GI:39973965
Neurospora crassa (Ncr) NCU06877.1 GI:32413367


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000004372
ISS
SpoSPAC3H8.02
GO:0005739 mitochondrion C
IDA
SceS000004372
GO:0005792 microsome C
IDA
SceS000004372
GO:0005811 lipid particle C
IDA
SceS000004372
GO:0005829 cytosol C
IDA
SceS000004372
GO:0008526 phosphatidylinositol transporter
activity		 F
IDA
SceS000004372
ISS
SpoSPAC3H8.02
GO:0007047 cellular cell wall organization P
ISS
SpoSPAC3H8.02
GO:0015914 phospholipid transport P
IDA
SceS000004372
ISS
SpoSPAC3H8.02
GO:0019217 regulation of fatty acid metabolic
process		 P
IGI
SceS000004372
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000004372
GO:0031505 fungal-type cell wall organization P
IGI
SceS000004372

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2352

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga969 ENSANGP00000017770
Ashbya gossypii (Ago) ago2546 AER041W
Arabidopsis thaliana (Ath) ath71 At1g01630.1
Arabidopsis thaliana (Ath) ath28421 At5g63060.1
Caenorhabditis elegans (Cel) cel363 B0336.11a
(CE39202;
WBGene00015148)
Candida glabrata (Cgl) cgl700 CAGL0D00946g
Candida glabrata (Cgl) cgl2280 CAGL0H05005g
Dictyostelium discoideum (Ddi) ddi3984 DDB0169539
Debaryomyces hansenii (Dha) dha228 DEHA0A05148g
Drosophila melanogaster (Dme) dme8158 CG32407-PA
(FBgn0052407)
Drosophila melanogaster (Dme) dme7677 CG32485-PA
(FBgn0052485)
Danio rerio (Dre) dre8749 ENSDARP00000034076
(mospd2)		 Q5U377
Takifugu rubripes (Fru) fru29962 SINFRUP00000144789
Gallus gallus (Gga) gga2417 ENSGALP00000026692
(MOSPD2)
Homo sapiens (Hsa) hsa32470 ENSP00000252430
Kluyveromyces lactis (Kla) kla3186 KLLA0E05313g
Mus musculus (Mmu) mmu29865 ENSMUSP00000004715
(MGI:1924013)		 Q9CWP6-4
Neurospora crassa (Ncr) ncr6690 NCU06877.2
Oryza sativa (Osa) osa32060 4445.m00119
Oryza sativa (Osa) osa33969 4658.m00124
Oryza sativa (Osa) osa49634 5742.m00188
Oryza sativa (Osa) osa54068 6301.m00182
Rattus norvegicus (Rno) rno31281 ENSRNOP00000004494
(RGD:1563952)
Rattus norvegicus (Rno) rno31280 ENSRNOP00000004533
(RGD:1563952)
Rattus norvegicus (Rno) rno31279 ENSRNOP00000039067
Saccharomyces cerevisiae (Sce) sce4498 YLR380W
(S000004372)
Schizosaccharomyces pombe (Spo) spo4891 SPAC3H8.02 Q10138
Schizosaccharomyces pombe (Spo) spo3299 SPAC589.09 Q9HDZ5
Yarrowia lipolytica (Yli) yli1937 YALI0C05511g
Yarrowia lipolytica (Yli) yli2426 YALI0C17545g
Yarrowia lipolytica (Yli) yli4831 YALI0E23430g
Yarrowia lipolytica (Yli) yli5026 YALI0E28292g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g01630
MmuMGI:1924013
GO:0005737 cytoplasm C
IDA
SceS000004372
ISS
SpoSPAC589.09
SPAC3H8.02
GO:0005739 mitochondrion C
IDA
SceS000004372
SpoSPAC589.09
GO:0005792 microsome C
IDA
SceS000004372
GO:0005811 lipid particle C
IDA
SceS000004372
GO:0005829 cytosol C
IDA
SceS000004372
GO:0009507 chloroplast C
IDA
AthAt5g63060
GO:0003674 molecular_function F
ND
MmuMGI:1924013
GO:0005215 transporter activity F
ISS
AthAt5g63060
At1g01630
GO:0008525 phosphatidylcholine transmembrane transporter
activity		 F
ISS
SpoSPAC589.09
GO:0008526 phosphatidylinositol transporter
activity		 F
IDA
SceS000004372
ISS
SpoSPAC3H8.02
SPAC589.09
GO:0006810 transport P
ISS
AthAt5g63060
At1g01630
GO:0007047 cellular cell wall organization P
ISS
SpoSPAC3H8.02
SPAC589.09
GO:0008150 biological_process P
ND
MmuMGI:1924013
GO:0015914 phospholipid transport P
IDA
SceS000004372
ISS
SpoSPAC589.09
SPAC3H8.02
GO:0019217 regulation of fatty acid metabolic
process		 P
IGI
SceS000004372
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000004372
GO:0031505 fungal-type cell wall organization P
IGI
SceS000004372

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC365.01
(Q9UUC2)		 YLR380W
(S000004372)
SPAC589.09
(Q9HDZ5)		 YLR380W
(S000004372)
SPAC3H8.02
(Q10138)		 YLR380W
(S000004372)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC365.01
GO:0005737 cytoplasm C
IDA
SceS000004372
ISS
SpoSPAC589.09
SPAC3H8.02
SPBC365.01
GO:0005739 mitochondrion C
IDA
SceS000004372
SpoSPAC589.09
GO:0005792 microsome C
IDA
SceS000004372
GO:0005811 lipid particle C
IDA
SceS000004372
GO:0005829 cytosol C
IDA
SceS000004372
SpoSPBC365.01
GO:0032153 cell division site C
IDA
SpoSPBC365.01
GO:0051286 cell tip C
IDA
SpoSPBC365.01
GO:0008525 phosphatidylcholine transmembrane transporter
activity		 F
ISS
SpoSPBC365.01
SPAC589.09
GO:0008526 phosphatidylinositol transporter
activity		 F
IDA
SceS000004372
ISS
SpoSPBC365.01
SPAC3H8.02
SPAC589.09
GO:0007047 cellular cell wall organization P
ISS
SpoSPAC3H8.02
SPAC589.09
SPBC365.01
GO:0015914 phospholipid transport P
IDA
SceS000004372
ISS
SpoSPAC589.09
SPAC3H8.02
SPBC365.01
GO:0019217 regulation of fatty acid metabolic
process		 P
IGI
SceS000004372
GO:0030433 ER-associated protein catabolic
process		 P
IMP
SceS000004372
GO:0031505 fungal-type cell wall organization P
IGI
SceS000004372

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s.khadayate@ucl.ac.uk