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Search term: YLR383W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SMC6
SGD link S000004375
Alternative ID YLR383W
Description Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 complex; required for growth, DNA repair, interchromosomal and sister chromatid recombination; homologous to S. pombe rad18
Synonyms YLR383W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0250 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA repair protein RAD18 (SMC family protein)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g07660 GI:15240835
Arabidopsis thaliana (Ath) At5g61460 GI:15240258
Caenorhabditis elegans (Cel) CE08332
(WBGene00007694)		 GI:17550582 Q93250
Caenorhabditis elegans (Cel) CE18730
(WBGene00010056)		 GI:17534363 Q9XTI9
Drosophila melanogaster (Dme) 7301120 GI:7301120
Homo sapiens (Hsa) Hs13375848 GI:13375848 Q96SB8
Saccharomyces cerevisiae (Sce) YLR383w
(S000004375)		 GI:6323415 Q12749
Schizosaccharomyces pombe (Spo) SPCC5E4.06 GI:19075406 P53692
Encephalitozoon cuniculi (Ecu) ECU07g0390 GI:19074461 Q8SRL3
Arabidopsis thaliana (Ath) At5g07660 GI:15240835
Arabidopsis thaliana (Ath) At5g61460 GI:15240258
Caenorhabditis elegans (Cel) CE08332
(WBGene00007694)		 GI:17550582 Q93250
Caenorhabditis elegans (Cel) CE18730
(WBGene00010056)		 GI:17534363 Q9XTI9
Drosophila melanogaster (Dme) 7301120 GI:7301120
Homo sapiens (Hsa) Hs13375848 GI:13375848 Q96SB8
Saccharomyces cerevisiae (Sce) YLR383w
(S000004375)		 GI:6323415 Q12749
Schizosaccharomyces pombe (Spo) SPCC5E4.06 GI:19075406 P53692
Encephalitozoon cuniculi (Ecu) ECU07g0390 GI:19074461 Q8SRL3
Arabidopsis thaliana (Ath) At5g07660 GI:15240835
Arabidopsis thaliana (Ath) At5g61460 GI:15240258
Caenorhabditis elegans (Cel) CE08332
(WBGene00007694)		 GI:17550582 Q93250
Caenorhabditis elegans (Cel) CE18730
(WBGene00010056)		 GI:17534363 Q9XTI9
Drosophila melanogaster (Dme) 7301120 GI:7301120
Homo sapiens (Hsa) Hs13375848 GI:13375848 Q96SB8
Saccharomyces cerevisiae (Sce) YLR383w
(S000004375)		 GI:6323415 Q12749
Schizosaccharomyces pombe (Spo) SPCC5E4.06 GI:19075406 P53692
Encephalitozoon cuniculi (Ecu) ECU07g0390 GI:19074461 Q8SRL3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SpoSPCC5E4.06
IDA
SceS000004375
SpoSPCC5E4.06
ISS
AthAt5g07660
At5g61460
GO:0005739 mitochondrion C
IDA
SceS000004375
GO:0030915 Smc5-Smc6 complex C
IDA
SpoSPCC5E4.06
IPI
SceS000004375
GO:0003674 molecular_function F
ND
SceS000004375
GO:0005515 protein binding F
IPI
SpoSPCC5E4.06
GO:0005524 ATP binding F
ISS
AthAt5g61460
At5g07660
GO:0046982 protein heterodimerization activity F
IPI
SpoSPCC5E4.06
GO:0000724 double-strand break repair via homologous
recombination		 P
IMP
AthAt5g61460
At5g07660
TAS
SpoSPCC5E4.06
GO:0006281 DNA repair P
IDA
SceS000004375
IMP
SceS000004375
SpoSPCC5E4.06
GO:0006302 double-strand break repair P
IMP
AthAt5g61460
GO:0006974 response to DNA damage stimulus P
IMP
SpoSPCC5E4.06
GO:0007059 chromosome segregation P
ISS
AthAt5g07660
At5g61460
GO:0007062 sister chromatid cohesion P
IMP
AthAt5g61460
At5g07660
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010056
GO:0010165 response to X-ray P
IMP
AthAt5g61460
At5g07660
GO:0048478 replication fork protection P
IC
SpoSPCC5E4.06

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
41575

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SMC6 GI:214010216
Pan troglodytes (Ptr) SMC6 GI:114576261
Canis familiaris (Cfa) SMC6 GI:73980575
Mus musculus (Mmu) Smc6
(MGI:1914491)		 GI:24415998 Q924W5
Rattus norvegicus (Rno) Smc6l1 GI:109477990
Gallus gallus (Gga) SMC6 GI:50745053
Drosophila melanogaster (Dme) CG5524
(FBgn0039164)		 GI:24649575
Anopheles gambiae (Aga) AgaP_AGAP002985 GI:118781858
Caenorhabditis elegans (Cel) C23H4.6
(CE08332;
WBGene00007694)		 GI:17550582 Q93250
Caenorhabditis elegans (Cel) F54D5.14
(CE18730;
WBGene00010056)		 GI:17534363 Q9XTI9
Schizosaccharomyces pombe (Spo) rad18
(SPCC5E4.06)		 GI:19075406 P53692
Saccharomyces cerevisiae (Sce) SMC6
(S000004375)		 GI:6323415 Q12749
Kluyveromyces lactis (Kla) KLLA0E05247g GI:50308365
Eremothecium gossypii (Ego) AGOS_AER044W GI:45190650
Magnaporthe grisea (Mgr) MGG_13522 GI:145616092
Neurospora crassa (Ncr) NCU02402.1 GI:32421469
Arabidopsis thaliana (Ath) AT5G07660 GI:15240835
Arabidopsis thaliana (Ath) MIM GI:15240258
Oryza sativa (Osa) Os09g0121000 GI:115478002


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1914491
GO:0005622 intracellular C
IDA
HsaSMC6
GO:0005634 nucleus C
IC
SpoSPCC5E4.06
IDA
SceS000004375
SpoSPCC5E4.06
ISS
AthAt5g07660
MIM
GO:0005739 mitochondrion C
IDA
SceS000004375
GO:0030915 Smc5-Smc6 complex C
IDA
SpoSPCC5E4.06
IPI
SceS000004375
GO:0003674 molecular_function F
ND
MmuMGI:1914491
SceS000004375
GO:0005515 protein binding F
IPI
SpoSPCC5E4.06
GO:0005524 ATP binding F
ISS
AthAt5g07660
MIM
GO:0046982 protein heterodimerization activity F
IPI
SpoSPCC5E4.06
GO:0000724 double-strand break repair via homologous
recombination		 P
IMP
AthMIM
At5g07660
TAS
SpoSPCC5E4.06
GO:0006281 DNA repair P
IDA
SceS000004375
IMP
SceS000004375
SpoSPCC5E4.06
ISS
DmeFBgn0039164
GO:0006302 double-strand break repair P
IMP
AthMIM
GO:0006974 response to DNA damage stimulus P
IMP
SpoSPCC5E4.06
GO:0007059 chromosome segregation P
ISS
AthMIM
At5g07660
GO:0007062 sister chromatid cohesion P
IMP
AthMIM
At5g07660
GO:0008150 biological_process P
ND
MmuMGI:1914491
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010056
GO:0010165 response to X-ray P
IMP
AthAt5g07660
MIM
GO:0048478 replication fork protection P
IC
SpoSPCC5E4.06

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1524

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5239 ENSANGP00000018189
Anopheles gambiae (Aga) aga5240 ENSANGP00000018267
Ashbya gossypii (Ago) ago2549 AER044W
Arabidopsis thaliana (Ath) ath22980 At5g07660.1
Arabidopsis thaliana (Ath) ath28241 At5g61460.1
Caenorhabditis elegans (Cel) cel2510 C23H4.6
(CE08332;
WBGene00007694)
Caenorhabditis elegans (Cel) cel10208 F54D5.14
(CE18730;
WBGene00010056)
Candida glabrata (Cgl) cgl2283 CAGL0H05071g
Cryptococcus neoformans (Cne) cne546 163.m06459
Dictyostelium discoideum (Ddi) ddi12865 DDB0231143
Debaryomyces hansenii (Dha) dha237 DEHA0A05346g
Drosophila melanogaster (Dme) dme14169 CG5524-PA
(FBgn0039164)
Danio rerio (Dre) dre10763 ENSDARP00000015079
Danio rerio (Dre) dre10764 ENSDARP00000039138
Encephalitozoon cuniculi (Ecu) ecu1847 19074461
Takifugu rubripes (Fru) fru21261 SINFRUP00000134961
Gallus gallus (Gga) gga16009 ENSGALP00000026518
(SMC6)
Gallus gallus (Gga) gga16010 ENSGALP00000026519
Gallus gallus (Gga) gga16011 ENSGALP00000026520
Homo sapiens (Hsa) hsa17496 ENSP00000323439
(SMC6)		 Q96SB8-1
Kluyveromyces lactis (Kla) kla3183 KLLA0E05247g
Mus musculus (Mmu) mmu5474 ENSMUSP00000020931
(MGI:1914491)		 Q924W5-1
Neurospora crassa (Ncr) ncr2335 NCU02402.2
Oryza sativa (Osa) osa4537 2282.m00116
Oryza sativa (Osa) osa54589 6080.m00158
Rattus norvegicus (Rno) rno24888 ENSRNOP00000007073
(RGD:1311214)
Saccharomyces cerevisiae (Sce) sce4501 YLR383W
(S000004375)
Schizosaccharomyces pombe (Spo) spo3684 SPCC5E4.06 P53692
Yarrowia lipolytica (Yli) yli60 YALI0A01606g
Yarrowia lipolytica (Yli) yli59 YALI0A01606g
Yarrowia lipolytica (Yli) yli5433 YALI0F02365g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1914491
GO:0005634 nucleus C
IC
SpoSPCC5E4.06
IDA
SceS000004375
SpoSPCC5E4.06
ISS
AthAt5g07660
At5g61460
GO:0005739 mitochondrion C
IDA
SceS000004375
GO:0030915 Smc5-Smc6 complex C
IDA
SpoSPCC5E4.06
IPI
SceS000004375
GO:0003674 molecular_function F
ND
MmuMGI:1914491
SceS000004375
GO:0005515 protein binding F
IPI
SpoSPCC5E4.06
GO:0005524 ATP binding F
ISS
AthAt5g61460
At5g07660
GO:0046982 protein heterodimerization activity F
IPI
SpoSPCC5E4.06
GO:0000724 double-strand break repair via homologous
recombination		 P
IMP
AthAt5g61460
At5g07660
TAS
SpoSPCC5E4.06
GO:0006281 DNA repair P
IDA
SceS000004375
IMP
SceS000004375
SpoSPCC5E4.06
ISS
DmeFBgn0039164
GO:0006302 double-strand break repair P
IMP
AthAt5g61460
GO:0006974 response to DNA damage stimulus P
IMP
SpoSPCC5E4.06
GO:0007059 chromosome segregation P
ISS
AthAt5g07660
At5g61460
GO:0007062 sister chromatid cohesion P
IMP
AthAt5g61460
At5g07660
GO:0008150 biological_process P
ND
MmuMGI:1914491
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010056
GO:0010165 response to X-ray P
IMP
AthAt5g61460
At5g07660
GO:0048478 replication fork protection P
IC
SpoSPCC5E4.06

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC5E4.06
(P53692)		 YLR383W
(S000004375)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SpoSPCC5E4.06
IDA
SceS000004375
SpoSPCC5E4.06
GO:0005739 mitochondrion C
IDA
SceS000004375
GO:0030915 Smc5-Smc6 complex C
IDA
SpoSPCC5E4.06
IPI
SceS000004375
GO:0003674 molecular_function F
ND
SceS000004375
GO:0005515 protein binding F
IPI
SpoSPCC5E4.06
GO:0046982 protein heterodimerization activity F
IPI
SpoSPCC5E4.06
GO:0000724 double-strand break repair via homologous
recombination		 P
TAS
SpoSPCC5E4.06
GO:0006281 DNA repair P
IDA
SceS000004375
IMP
SceS000004375
SpoSPCC5E4.06
GO:0006974 response to DNA damage stimulus P
IMP
SpoSPCC5E4.06
GO:0048478 replication fork protection P
IC
SpoSPCC5E4.06

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GO info in one table:

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