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Search term: YLR398C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SKI2
SGD link S000004390
Alternative ID YLR398C
Description Ski complex component and putative RNA helicase, mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay
Synonyms YLR398C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0947 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Cytoplasmic exosomal RNA helicase SKI2, DEAD-box superfamily

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g70070 GI:15223032
Arabidopsis thaliana (Ath) At3g46960 GI:15232685
Caenorhabditis elegans (Cel) CE20651 GI:17539644
Drosophila melanogaster (Dme) 7301051 GI:7301051
Homo sapiens (Hsa) Hs20631987 GI:20631987
Saccharomyces cerevisiae (Sce) YLR398c
(S000004390)		 GI:6323430 P35207
Schizosaccharomyces pombe (Spo) SPCC550.03c GI:19075595 O59801
Encephalitozoon cuniculi (Ecu) ECU04g1290 GI:19074207 Q8SS19
Arabidopsis thaliana (Ath) At1g70070 GI:15223032
Arabidopsis thaliana (Ath) At3g46960 GI:15232685
Caenorhabditis elegans (Cel) CE20651 GI:17539644
Drosophila melanogaster (Dme) 7301051 GI:7301051
Homo sapiens (Hsa) Hs20631987 GI:20631987
Saccharomyces cerevisiae (Sce) YLR398c
(S000004390)		 GI:6323430 P35207
Schizosaccharomyces pombe (Spo) SPCC550.03c GI:19075595 O59801
Encephalitozoon cuniculi (Ecu) ECU04g1290 GI:19074207 Q8SS19


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
ISS
SpoSPCC550.03c
GO:0005737 cytoplasm C
ISS
SpoSPCC550.03c
GO:0005773 vacuole C
IDA
AthAt3g46960
GO:0005829 cytosol C
IDA
SpoSPCC550.03c
GO:0009507 chloroplast C
IDA
AthAt1g70070
GO:0009570 chloroplast stroma C
IDA
AthAt1g70070
GO:0010494 stress granule C
IDA
AthAt1g70070
GO:0055087 Ski complex C
IDA
SceS000004390
IPI
SceS000004390
ISS
SpoSPCC550.03c
GO:0003724 RNA helicase activity F
ISS
AthAt1g70070
SceS000004390
SpoSPCC550.03c
GO:0008026 ATP-dependent helicase activity F
ISS
AthAt1g70070
At3g46960
GO:0006402 mRNA catabolic process P
ISS
SpoSPCC550.03c
GO:0006417 regulation of translation P
ISS
SpoSPCC550.03c
GO:0008150 biological_process P
ND
AthAt3g46960
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt1g70070
GO:0010497 plasmodesmata-mediated intercellular
transport		 P
IMP
AthAt1g70070
NAS
AthAt1g70070
GO:0016441 posttranscriptional gene silencing P
IMP
AthAt1g70070
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IMP
SceS000004390
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000004390
IMP
SceS000004390
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000004390

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6532

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SKIV2L GI:67782311
Pan troglodytes (Ptr) SKIV2L GI:114606536
Canis familiaris (Cfa) SKIV2L GI:73972333
Mus musculus (Mmu) Skiv2l
(MGI:1099835)		 GI:87252727 Q3TE28
Rattus norvegicus (Rno) Skiv2l
(RGD:1303059)		 GI:47087109
Drosophila melanogaster (Dme) tst
(FBgn0039117)		 GI:17933658
Anopheles gambiae (Aga) AgaP_AGAP003182 GI:118783278
Caenorhabditis elegans (Cel) F01G4.3
(CE40452;
WBGene00008502)		 GI:133930973
Schizosaccharomyces pombe (Spo) SPCC550.03c GI:19075595 O59801
Saccharomyces cerevisiae (Sce) SKI2
(S000004390)		 GI:6323430 P35207
Eremothecium gossypii (Ego) AGOS_AER067C GI:45190673
Magnaporthe grisea (Mgr) MGG_12704 GI:145610494
Neurospora crassa (Ncr) NCU01857.1 GI:32417138
Arabidopsis thaliana (Ath) AT3G46960 GI:79436763


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
DmeFBgn0039117
GO:0005730 nucleolus C
ISS
SpoSPCC550.03c
GO:0005737 cytoplasm C
ISS
SpoSPCC550.03c
GO:0005773 vacuole C
IDA
AthAt3g46960
GO:0005829 cytosol C
IDA
SpoSPCC550.03c
GO:0055087 Ski complex C
IDA
SceS000004390
IPI
SceS000004390
ISS
SpoSPCC550.03c
GO:0003724 RNA helicase activity F
ISS
SceS000004390
SpoSPCC550.03c
GO:0004004 ATP-dependent RNA helicase activity F
TAS
HsaSKIV2L
GO:0004386 helicase activity F
ISS
DmeFBgn0039117
GO:0005515 protein binding F
IPI
HsaSKIV2L
GO:0008026 ATP-dependent helicase activity F
ISS
AthAt3g46960
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IMP
DmeFBgn0039117
GO:0006402 mRNA catabolic process P
ISS
SpoSPCC550.03c
GO:0006417 regulation of translation P
ISS
SpoSPCC550.03c
GO:0008150 biological_process P
ND
AthAt3g46960
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IMP
SceS000004390
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000004390
IMP
SceS000004390
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000004390

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1709

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5475 ENSANGP00000014710
Ashbya gossypii (Ago) ago2572 AER067C
Arabidopsis thaliana (Ath) ath15977 At3g46960.1
Caenorhabditis elegans (Cel) cel5418 F01G4.3
(CE40452;
WBGene00008502)
Candida glabrata (Cgl) cgl528 CAGL0C02563g
Cryptococcus neoformans (Cne) cne70 162.m02827
Dictyostelium discoideum (Ddi) ddi3370 DDB0169070
Debaryomyces hansenii (Dha) dha525 DEHA0A11715g
Drosophila melanogaster (Dme) dme14077 CG10210-PA
(FBgn0039117)
Danio rerio (Dre) dre10122 ENSDARP00000020964
Danio rerio (Dre) dre10123 ENSDARP00000028731
Danio rerio (Dre) dre26410 ENSDARP00000036170
Danio rerio (Dre) dre10124 ENSDARP00000046621
Danio rerio (Dre) dre10125 ENSDARP00000049670
Encephalitozoon cuniculi (Ecu) ecu845 19074207
Takifugu rubripes (Fru) fru1689 SINFRUP00000153955
Takifugu rubripes (Fru) fru1690 SINFRUP00000173752
Takifugu rubripes (Fru) fru1688 SINFRUP00000175902
Homo sapiens (Hsa) hsa26869 ENSP00000347346
Kluyveromyces lactis (Kla) kla672 KLLA0B03179g
Mus musculus (Mmu) mmu11506 ENSMUSP00000036265
(MGI:1099835)		 O70349
Neurospora crassa (Ncr) ncr1807 NCU01857.2
Oryza sativa (Osa) osa28249 4241.m00234
Plasmodium falciparum (Pfa) pfa4563 PFI0480w
Rattus norvegicus (Rno) rno17461 ENSRNOP00000000481
(RGD:1303059)		 Q6MG76
Saccharomyces cerevisiae (Sce) sce4516 YLR398C
(S000004390)
Schizosaccharomyces pombe (Spo) spo3197 SPCC550.03c O59801
Yarrowia lipolytica (Yli) yli402 YALI0A11869g
Yarrowia lipolytica (Yli) yli446 YALI0A13519g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
DmeFBgn0039117
GO:0005730 nucleolus C
ISS
SpoSPCC550.03c
GO:0005737 cytoplasm C
ISS
SpoSPCC550.03c
GO:0005773 vacuole C
IDA
AthAt3g46960
GO:0005829 cytosol C
IDA
SpoSPCC550.03c
GO:0055087 Ski complex C
IDA
SceS000004390
IPI
SceS000004390
ISS
SpoSPCC550.03c
GO:0003724 RNA helicase activity F
ISS
SceS000004390
SpoSPCC550.03c
GO:0004386 helicase activity F
ISS
DmeFBgn0039117
GO:0008026 ATP-dependent helicase activity F
ISS
AthAt3g46960
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IMP
DmeFBgn0039117
GO:0006402 mRNA catabolic process P
ISS
SpoSPCC550.03c
GO:0006417 regulation of translation P
ISS
SpoSPCC550.03c
GO:0008150 biological_process P
ND
AthAt3g46960
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IMP
SceS000004390
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000004390
IMP
SceS000004390
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000004390

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC550.03c
(O59801)		 YLR398C
(S000004390)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005730 nucleolus C
ISS
SpoSPCC550.03c
GO:0005737 cytoplasm C
ISS
SpoSPCC550.03c
GO:0005829 cytosol C
IDA
SpoSPCC550.03c
GO:0055087 Ski complex C
IDA
SceS000004390
IPI
SceS000004390
ISS
SpoSPCC550.03c
GO:0003724 RNA helicase activity F
ISS
SceS000004390
SpoSPCC550.03c
GO:0006402 mRNA catabolic process P
ISS
SpoSPCC550.03c
GO:0006417 regulation of translation P
ISS
SpoSPCC550.03c
GO:0034427 nuclear-transcribed mRNA catabolic process,
exonucleolytic, 3'-5'		 P
IMP
SceS000004390
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000004390
IMP
SceS000004390
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000004390

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GO info in one table:

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