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Search term: YLR409C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name UTP21
SGD link S000004401
Alternative ID YLR409C
Description Subunit of U3-containing 90S preribosome and Small Subunit (SSU) processome complexes involved in production of 18S rRNA and assembly of small ribosomal subunit; synthetic defect with STI1 Hsp90 cochaperone; human homolog linked to glaucoma
Synonyms YLR409C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1539 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED WD repeat protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g04940 GI:4325344
Caenorhabditis elegans (Cel) CE25731 GI:17543478
Drosophila melanogaster (Dme) 7299761 GI:7299761
Homo sapiens (Hsa) Hs21281677
(WDR36)
GI:21281677 Q8NI36
Saccharomyces cerevisiae (Sce) YLR409c
(S000004401)
GI:6323441 Q06078
Schizosaccharomyces pombe (Spo) SPCC1672.07 GI:19075378 O14053
Encephalitozoon cuniculi (Ecu) ECU06g0370i GI:19074287 Q8SVE1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaWDR36
GO:0005634 nucleus C
IDA
SceS000004401
SpoSPCC1672.07
GO:0005730 nucleolus C
IDA
SceS000004401
NAS
SpoSPCC1672.07
GO:0005732 small nucleolar ribonucleoprotein
complex
C
ISS
SpoSPCC1672.07
GO:0005816 spindle pole body C
IDA
SpoSPCC1672.07
GO:0005819 spindle C
IDA
SpoSPCC1672.07
GO:0005829 cytosol C
IDA
SpoSPCC1672.07
GO:0030686 90S preribosome C
IDA
SceS000004401
GO:0032040 small-subunit processome C
IDA
SceS000004401
GO:0032153 cell division site C
IDA
SpoSPCC1672.07
GO:0034388 Pwp2p-containing subcomplex of 90S
preribosome
C
IDA
SceS000004401
GO:0043234 protein complex C
NAS
SpoSPCC1672.07
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt4g04940
GO:0000166 nucleotide binding F
ISS
AthAt4g04940
GO:0003674 molecular_function F
ND
HsaWDR36
SceS000004401
SpoSPCC1672.07
GO:0030515 snoRNA binding F
RCA
SceS000004401
GO:0006364 rRNA processing P
IGI
SceS000004401
ISS
SpoSPCC1672.07
GO:0008150 biological_process P
ND
HsaWDR36
GO:0042274 ribosomal small subunit biogenesis P
IC
SceS000004401

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6536

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) WDR36 GI:21281677 Q8NI36
Pan troglodytes (Ptr) WDR36 GI:114601108
Canis familiaris (Cfa) WDR36 GI:73952167
Rattus norvegicus (Rno) LOC688637 GI:109506418
Gallus gallus (Gga) WDR36 GI:113206056
Drosophila melanogaster (Dme) CG9799
(FBgn0038146)
GI:24646564
Anopheles gambiae (Aga) AgaP_AGAP004557 GI:118784646
Schizosaccharomyces pombe (Spo) SPCC1672.07 GI:19075378 O14053
Saccharomyces cerevisiae (Sce) UTP21
(S000004401)
GI:6323441 Q06078
Kluyveromyces lactis (Kla) KLLA0B02827g GI:50303433
Eremothecium gossypii (Ego) AGOS_AER081C GI:45190687
Magnaporthe grisea (Mgr) MGG_06038 GI:145603462
Neurospora crassa (Ncr) NCU07011.1 GI:32413635
Arabidopsis thaliana (Ath) AT4G04940 GI:18412751
Oryza sativa (Osa) Os06g0644600 GI:115469178
Plasmodium falciparum (Pfa) PF13_0309 GI:124513864


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaWDR36
GO:0005634 nucleus C
IDA
SceS000004401
SpoSPCC1672.07
GO:0005730 nucleolus C
IDA
SceS000004401
NAS
SpoSPCC1672.07
GO:0005732 small nucleolar ribonucleoprotein
complex
C
ISS
SpoSPCC1672.07
GO:0005816 spindle pole body C
IDA
SpoSPCC1672.07
GO:0005819 spindle C
IDA
SpoSPCC1672.07
GO:0005829 cytosol C
IDA
SpoSPCC1672.07
GO:0030686 90S preribosome C
IDA
SceS000004401
GO:0032040 small-subunit processome C
IDA
SceS000004401
GO:0032153 cell division site C
IDA
SpoSPCC1672.07
GO:0034388 Pwp2p-containing subcomplex of 90S
preribosome
C
IDA
SceS000004401
GO:0043234 protein complex C
NAS
SpoSPCC1672.07
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt4g04940
GO:0000166 nucleotide binding F
ISS
AthAt4g04940
GO:0003674 molecular_function F
ND
HsaWDR36
SceS000004401
SpoSPCC1672.07
GO:0030515 snoRNA binding F
RCA
SceS000004401
GO:0006364 rRNA processing P
IGI
SceS000004401
ISS
SpoSPCC1672.07
GO:0008150 biological_process P
ND
HsaWDR36
GO:0042274 ribosomal small subunit biogenesis P
IC
SceS000004401

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2115

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga7109 ENSANGP00000012199
Ashbya gossypii (Ago) ago2586 AER081C
Arabidopsis thaliana (Ath) ath18378 At4g04940.1
Caenorhabditis elegans (Cel) cel18928 Y45F10D.7
(CE39843;
WBGene00012887)
Candida glabrata (Cgl) cgl5086 CAGL0M09845g
Cryptococcus neoformans (Cne) cne596 163.m02731
Dictyostelium discoideum (Ddi) ddi2502 DDB0217865
Debaryomyces hansenii (Dha) dha2845 DEHA0D12342g
Drosophila melanogaster (Dme) dme12415 CG9799-PA
(FBgn0038146)
Danio rerio (Dre) dre31301 ENSDARP00000008668
(wdr36)
Q6DRC9
Encephalitozoon cuniculi (Ecu) ecu1514 19074287
Takifugu rubripes (Fru) fru10923 SINFRUP00000153742
Takifugu rubripes (Fru) fru10922 SINFRUP00000169604
Takifugu rubripes (Fru) fru10924 SINFRUP00000174480
Gallus gallus (Gga) gga4310 ENSGALP00000000325
(WDR36)
Q5ZHX4
Homo sapiens (Hsa) hsa25578 ENSP00000319771
(WDR36)
Q8NI36
Kluyveromyces lactis (Kla) kla656 KLLA0B02827g
Mus musculus (Mmu) mmu12463 ENSMUSP00000044409
Neurospora crassa (Ncr) ncr6823 NCU07011.2
Oryza sativa (Osa) osa1484 1926.m00126
Plasmodium falciparum (Pfa) pfa3825 PF13_0309
Rattus norvegicus (Rno) rno13913 ENSRNOP00000036935
(GI:688637)
Saccharomyces cerevisiae (Sce) sce4529 YLR409C
(S000004401)
Schizosaccharomyces pombe (Spo) spo1233 SPCC1672.07 O14053
Yarrowia lipolytica (Yli) yli1293 YALI0B13442g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004401
SpoSPCC1672.07
GO:0005730 nucleolus C
IDA
SceS000004401
NAS
SpoSPCC1672.07
GO:0005732 small nucleolar ribonucleoprotein
complex
C
ISS
SpoSPCC1672.07
GO:0005816 spindle pole body C
IDA
SpoSPCC1672.07
GO:0005819 spindle C
IDA
SpoSPCC1672.07
GO:0005829 cytosol C
IDA
SpoSPCC1672.07
GO:0030686 90S preribosome C
IDA
SceS000004401
GO:0032040 small-subunit processome C
IDA
SceS000004401
GO:0032153 cell division site C
IDA
SpoSPCC1672.07
GO:0034388 Pwp2p-containing subcomplex of 90S
preribosome
C
IDA
SceS000004401
GO:0043234 protein complex C
NAS
SpoSPCC1672.07
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt4g04940
GO:0000166 nucleotide binding F
ISS
AthAt4g04940
GO:0003674 molecular_function F
ND
SceS000004401
SpoSPCC1672.07
GO:0030515 snoRNA binding F
RCA
SceS000004401
GO:0002119 nematode larval development P
IMP
CelWBGene00012887
GO:0006364 rRNA processing P
IGI
SceS000004401
ISS
SpoSPCC1672.07
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00012887
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00012887
GO:0040007 growth P
IMP
CelWBGene00012887
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00012887
GO:0042274 ribosomal small subunit biogenesis P
IC
SceS000004401

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC1672.07
(O14053)
YLR409C
(S000004401)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004401
SpoSPCC1672.07
GO:0005730 nucleolus C
IDA
SceS000004401
NAS
SpoSPCC1672.07
GO:0005732 small nucleolar ribonucleoprotein
complex
C
ISS
SpoSPCC1672.07
GO:0005816 spindle pole body C
IDA
SpoSPCC1672.07
GO:0005819 spindle C
IDA
SpoSPCC1672.07
GO:0005829 cytosol C
IDA
SpoSPCC1672.07
GO:0030686 90S preribosome C
IDA
SceS000004401
GO:0032040 small-subunit processome C
IDA
SceS000004401
GO:0032153 cell division site C
IDA
SpoSPCC1672.07
GO:0034388 Pwp2p-containing subcomplex of 90S
preribosome
C
IDA
SceS000004401
GO:0043234 protein complex C
NAS
SpoSPCC1672.07
GO:0003674 molecular_function F
ND
SceS000004401
SpoSPCC1672.07
GO:0030515 snoRNA binding F
RCA
SceS000004401
GO:0006364 rRNA processing P
IGI
SceS000004401
ISS
SpoSPCC1672.07
GO:0042274 ribosomal small subunit biogenesis P
IC
SceS000004401

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s.khadayate@ucl.ac.uk