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Search term: YLR417W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name VPS36
SGD link S000004409
Alternative ID YLR417W
Description Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome
Synonyms YLR417W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2760 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Vacuolar sorting protein VPS36

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g04920 GI:15238374
Caenorhabditis elegans (Cel) CE05655 GI:17559822
Drosophila melanogaster (Dme) 7294458 GI:7294458
Homo sapiens (Hsa) Hs7705640 GI:7705640
Saccharomyces cerevisiae (Sce) YLR417w
(S000004409)		 GI:6323449 Q06696
Schizosaccharomyces pombe (Spo) SPBC3B9.09 GI:19113459 O43038


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000814 ESCRT II complex C
IDA
SceS000004409
ISS
AthAt5g04920
SpoSPBC3B9.09
GO:0005737 cytoplasm C
IDA
SpoSPBC3B9.09
GO:0005794 Golgi apparatus C
IDA
SpoSPBC3B9.09
GO:0005215 transporter activity F
ISS
AthAt5g04920
GO:0043130 ubiquitin binding F
IDA
SceS000004409
GO:0000433 negative regulation of transcription from RNA
polymerase II promoter by glucose		 P
IMP
SceS000004409
GO:0006623 protein targeting to vacuole P
IMP
SceS000004409
IPI
SceS000004409
GO:0016192 vesicle-mediated transport P
ISS
AthAt5g04920
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IC
SceS000004409
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SpoSPBC3B9.09
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000004409
ISS
SpoSPBC3B9.09
GO:0045324 late endosome to vacuole transport P
IMP
SpoSPBC3B9.09

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
104097

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC3B9.09 GI:19113459 O43038
Saccharomyces cerevisiae (Sce) VPS36
(S000004409)		 GI:6323449 Q06696
Kluyveromyces lactis (Kla) KLLA0B02541g GI:50303407
Eremothecium gossypii (Ego) AGOS_AER092W GI:45190698


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000814 ESCRT II complex C
IDA
SceS000004409
ISS
SpoSPBC3B9.09
GO:0005737 cytoplasm C
IDA
SpoSPBC3B9.09
GO:0005794 Golgi apparatus C
IDA
SpoSPBC3B9.09
GO:0043130 ubiquitin binding F
IDA
SceS000004409
GO:0000433 negative regulation of transcription from RNA
polymerase II promoter by glucose		 P
IMP
SceS000004409
GO:0006623 protein targeting to vacuole P
IMP
SceS000004409
IPI
SceS000004409
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IC
SceS000004409
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SpoSPBC3B9.09
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000004409
ISS
SpoSPBC3B9.09
GO:0045324 late endosome to vacuole transport P
IMP
SpoSPBC3B9.09

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3375

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga88 ENSANGP00000026040
Ashbya gossypii (Ago) ago2597 AER092W
Arabidopsis thaliana (Ath) ath22662 At5g04920.1
Caenorhabditis elegans (Cel) cel6590 F17C11.8
(CE38502;
WBGene00008919)
Candida glabrata (Cgl) cgl3184 CAGL0J04488g
Cryptococcus neoformans (Cne) cne2019 181.m08000
Dictyostelium discoideum (Ddi) ddi5364 DDB0205116
Debaryomyces hansenii (Dha) dha2639 DEHA0D07733g
Drosophila melanogaster (Dme) dme9397 CG10711-PA
(FBgn0036375)
Danio rerio (Dre) dre1646 ENSDARP00000027551
Danio rerio (Dre) dre5157 ENSDARP00000046088
Takifugu rubripes (Fru) fru22415 SINFRUP00000141611
Gallus gallus (Gga) gga3021 ENSGALP00000027458
(VPS36)
Homo sapiens (Hsa) hsa8837 ENSP00000258599
Kluyveromyces lactis (Kla) kla643 KLLA0B02541g
Mus musculus (Mmu) mmu25724 ENSMUSP00000033866
(MGI:1917410)		 Q91XD6
Neurospora crassa (Ncr) ncr6413 NCU06595.2
Oryza sativa (Osa) osa13143 2918.m00139
Rattus norvegicus (Rno) rno12690 ENSRNOP00000016995
(RGD:1309754)		 B1H248
Saccharomyces cerevisiae (Sce) sce4540 YLR417W
(S000004409)
Schizosaccharomyces pombe (Spo) spo3942 SPBC3B9.09 O43038
Yarrowia lipolytica (Yli) yli2756 YALI0D01177g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000814 ESCRT II complex C
IDA
SceS000004409
ISS
AthAt5g04920
SpoSPBC3B9.09
GO:0005737 cytoplasm C
IDA
SpoSPBC3B9.09
GO:0005764 lysosome C
IDA
MmuMGI:1917410
GO:0005770 late endosome C
IDA
MmuMGI:1917410
GO:0005794 Golgi apparatus C
IDA
SpoSPBC3B9.09
GO:0005215 transporter activity F
ISS
AthAt5g04920
GO:0043130 ubiquitin binding F
IDA
MmuMGI:1917410
SceS000004409
GO:0000003 reproduction P
IMP
CelWBGene00008919
GO:0000433 negative regulation of transcription from RNA
polymerase II promoter by glucose		 P
IMP
SceS000004409
GO:0002119 nematode larval development P
IMP
CelWBGene00008919
GO:0006623 protein targeting to vacuole P
IMP
SceS000004409
IPI
SceS000004409
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00008919
GO:0016192 vesicle-mediated transport P
ISS
AthAt5g04920
GO:0016197 endosome transport P
IC
MmuMGI:1917410
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00008919
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IC
SceS000004409
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SpoSPBC3B9.09
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000004409
ISS
SpoSPBC3B9.09
GO:0045324 late endosome to vacuole transport P
IMP
SpoSPBC3B9.09

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC3B9.09
(O43038)		 YLR417W
(S000004409)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000814 ESCRT II complex C
IDA
SceS000004409
ISS
SpoSPBC3B9.09
GO:0005737 cytoplasm C
IDA
SpoSPBC3B9.09
GO:0005794 Golgi apparatus C
IDA
SpoSPBC3B9.09
GO:0043130 ubiquitin binding F
IDA
SceS000004409
GO:0000433 negative regulation of transcription from RNA
polymerase II promoter by glucose		 P
IMP
SceS000004409
GO:0006623 protein targeting to vacuole P
IMP
SceS000004409
IPI
SceS000004409
GO:0043162 ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IC
SceS000004409
GO:0043328 protein targeting to vacuole involved in
ubiquitin-dependent protein catabolic process via
the multivesicular body sorting
pathway		 P
IMP
SpoSPBC3B9.09
GO:0045053 protein retention in Golgi apparatus P
IMP
SceS000004409
ISS
SpoSPBC3B9.09
GO:0045324 late endosome to vacuole transport P
IMP
SpoSPBC3B9.09

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