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Search term: YLR429W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name CRN1
SGD link S000004421
Alternative ID YLR429W
Description Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity; plays a role in regulation of actin patch assembly
Synonyms YLR429W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0303 -CDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Actin-binding protein Coronin, contains WD40 repeats

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE00590
(WBGene00000768)		 GI:17554434
Drosophila melanogaster (Dme) 7302313 GI:7302313 Q7JVY0
Homo sapiens (Hsa) Hs14149734
(CORO1B)		 GI:14149734 Q9NSK3
Homo sapiens (Hsa) Hs14249582 GI:14249582
Homo sapiens (Hsa) Hs16554583 GI:16554583
Homo sapiens (Hsa) Hs16554585 GI:16554585 Q92828
Homo sapiens (Hsa) Hs22041131 GI:22041131
Homo sapiens (Hsa) Hs22054763 GI:22054763
Homo sapiens (Hsa) Hs5902134
(CORO1A)		 GI:5902134 P31146
Homo sapiens (Hsa) Hs7656991
(CORO1C)		 GI:7656991 Q9ULV4
Saccharomyces cerevisiae (Sce) YLR429w
(S000004421)		 GI:6323460 Q06440
Schizosaccharomyces pombe (Spo) SPAC23C4.02 GI:19114087 O13923
Caenorhabditis elegans (Cel) CE00590
(WBGene00000768)		 GI:17554434
Drosophila melanogaster (Dme) 7302313 GI:7302313 Q7JVY0
Homo sapiens (Hsa) Hs14149734
(CORO1B)		 GI:14149734 Q9NSK3
Homo sapiens (Hsa) Hs14249582 GI:14249582
Homo sapiens (Hsa) Hs16554583 GI:16554583
Homo sapiens (Hsa) Hs16554585 GI:16554585 Q92828
Homo sapiens (Hsa) Hs22041131 GI:22041131
Homo sapiens (Hsa) Hs22054763 GI:22054763
Homo sapiens (Hsa) Hs5902134
(CORO1A)		 GI:5902134 P31146
Homo sapiens (Hsa) Hs7656991
(CORO1C)		 GI:7656991 Q9ULV4
Saccharomyces cerevisiae (Sce) YLR429w
(S000004421)		 GI:6323460 Q06440
Schizosaccharomyces pombe (Spo) SPAC23C4.02 GI:19114087 O13923
Caenorhabditis elegans (Cel) CE00590
(WBGene00000768)		 GI:17554434
Drosophila melanogaster (Dme) 7302313 GI:7302313 Q7JVY0
Homo sapiens (Hsa) Hs14149734
(CORO1B)		 GI:14149734 Q9NSK3
Homo sapiens (Hsa) Hs14249582 GI:14249582
Homo sapiens (Hsa) Hs16554583 GI:16554583
Homo sapiens (Hsa) Hs16554585 GI:16554585 Q92828
Homo sapiens (Hsa) Hs22041131 GI:22041131
Homo sapiens (Hsa) Hs22054763 GI:22054763
Homo sapiens (Hsa) Hs5902134
(CORO1A)		 GI:5902134 P31146
Homo sapiens (Hsa) Hs7656991
(CORO1C)		 GI:7656991 Q9ULV4
Saccharomyces cerevisiae (Sce) YLR429w
(S000004421)		 GI:6323460 Q06440
Schizosaccharomyces pombe (Spo) SPAC23C4.02 GI:19114087 O13923


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001891 phagocytic cup C
IDA
HsaCORO1A
GO:0005737 cytoplasm C
IDA
HsaCORO1A
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC23C4.02
GO:0005885 Arp2/3 protein complex C
IDA
SceS000004421
IPI
SceS000004421
GO:0005886 plasma membrane C
IDA
HsaCORO1A
GO:0015629 actin cytoskeleton C
TAS
HsaCORO1C
GO:0030027 lamellipodium C
IDA
HsaCORO1A
GO:0030479 actin cortical patch C
IDA
SceS000004421
SpoSPAC23C4.02
GO:0030864 cortical actin cytoskeleton C
IDA
HsaCORO1A
GO:0031941 filamentous actin C
IDA
HsaCORO1A
GO:0043234 protein complex C
IDA
HsaCORO1A
NAS
SpoSPAC23C4.02
GO:0045335 phagocytic vesicle C
IDA
HsaCORO1A
GO:0003779 actin binding F
ISS
SpoSPAC23C4.02
GO:0005515 protein binding F
IPI
HsaCORO1A
CORO1B
GO:0008017 microtubule binding F
IDA
SceS000004421
GO:0008022 protein C-terminus binding F
IPI
HsaCORO1A
GO:0008092 cytoskeletal protein binding F
ISS
HsaCORO1A
GO:0030674 protein binding, bridging F
IDA
SceS000004421
GO:0042803 protein homodimerization activity F
IDA
HsaCORO1A
GO:0043548 phosphoinositide 3-kinase binding F
IDA
HsaCORO1A
GO:0051015 actin filament binding F
IDA
HsaCORO1A
SceS000004421
GO:0000003 reproduction P
IMP
CelWBGene00000768
GO:0001845 phagolysosome assembly P
IMP
HsaCORO1A
GO:0006415 translational termination P
RCA
SceS000004421
GO:0006909 phagocytosis P
IMP
HsaCORO1A
TAS
HsaCORO1C
GO:0006928 cellular component movement P
NAS
HsaCORO1A
GO:0007015 actin filament organization P
IMP
SceS000004421
IPI
SceS000004421
GO:0007017 microtubule-based process P
IPI
SceS000004421
GO:0007126 meiosis P
IMP
CelWBGene00000768
GO:0007165 signal transduction P
TAS
HsaCORO1C
GO:0030036 actin cytoskeleton organization P
IMP
HsaCORO1A
ISS
SpoSPAC23C4.02
GO:0030041 actin filament polymerization P
NAS
SpoSPAC23C4.02
GO:0031589 cell-substrate adhesion P
IMP
HsaCORO1A
GO:0034316 negative regulation of Arp2/3 complex-mediated
actin nucleation		 P
IDA
SceS000004421
IMP
SceS000004421
GO:0045087 innate immune response P
NAS
HsaCORO1A
GO:0050918 positive chemotaxis P
IDA
HsaCORO1A
GO:0051017 actin filament bundle assembly P
TAS
SpoSPAC23C4.02
GO:0051049 regulation of transport P
RCA
SceS000004421
GO:0051126 negative regulation of actin nucleation P
IDA
HsaCORO1A
GO:0051666 actin cortical patch localization P
IMP
SceS000004421

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
104099

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CORO6 GI:109627650
Pan troglodytes (Ptr) CORO6 GI:114668343
Canis familiaris (Cfa) CORO6 GI:73967084
Mus musculus (Mmu) Coro6
(MGI:2183448)		 GI:41281697 A1ILN2
Rattus norvegicus (Rno) Coro6
(RGD:708560)		 GI:20806171
Schizosaccharomyces pombe (Spo) crn1
(SPAC23C4.02)		 GI:19114087 O13923
Saccharomyces cerevisiae (Sce) CRN1
(S000004421)		 GI:6323460 Q06440
Kluyveromyces lactis (Kla) KLLA0D02530g GI:50306415
Eremothecium gossypii (Ego) AGOS_AER114W GI:45190720
Magnaporthe grisea (Mgr) MGG_06389 GI:145608772
Neurospora crassa (Ncr) NCU00202.1 GI:32403350
Plasmodium falciparum (Pfa) PFL2460w GI:124807051


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2183448
PfaPFL2460w
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC23C4.02
GO:0005885 Arp2/3 protein complex C
IDA
SceS000004421
IPI
SceS000004421
GO:0030479 actin cortical patch C
IDA
SceS000004421
SpoSPAC23C4.02
GO:0043234 protein complex C
NAS
SpoSPAC23C4.02
GO:0003674 molecular_function F
ND
MmuMGI:2183448
GO:0003779 actin binding F
ISS
PfaPFL2460w
SpoSPAC23C4.02
GO:0008017 microtubule binding F
IDA
SceS000004421
GO:0030674 protein binding, bridging F
IDA
SceS000004421
GO:0051015 actin filament binding F
IDA
SceS000004421
GO:0000910 cytokinesis P
ISS
PfaPFL2460w
GO:0006415 translational termination P
RCA
SceS000004421
GO:0006928 cellular component movement P
ISS
PfaPFL2460w
GO:0007015 actin filament organization P
IMP
SceS000004421
IPI
SceS000004421
GO:0007017 microtubule-based process P
IPI
SceS000004421
ISS
PfaPFL2460w
GO:0008150 biological_process P
ND
MmuMGI:2183448
GO:0030036 actin cytoskeleton organization P
ISS
SpoSPAC23C4.02
GO:0030041 actin filament polymerization P
NAS
SpoSPAC23C4.02
GO:0034316 negative regulation of Arp2/3 complex-mediated
actin nucleation		 P
IDA
SceS000004421
IMP
SceS000004421
GO:0051017 actin filament bundle assembly P
TAS
SpoSPAC23C4.02
GO:0051049 regulation of transport P
RCA
SceS000004421
GO:0051666 actin cortical patch localization P
IMP
SceS000004421

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_675

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga1330 ENSANGP00000022450
Ashbya gossypii (Ago) ago2619 AER114W
Caenorhabditis elegans (Cel) cel13156 R01H10.3a
(CE00590;
WBGene00000768)
Caenorhabditis elegans (Cel) cel13157 R01H10.3b
(CE30350)
Caenorhabditis elegans (Cel) cel13158 R01H10.3c
(CE30351)
Caenorhabditis elegans (Cel) cel13159 R01H10.3d
(CE30352)
Candida glabrata (Cgl) cgl3198 CAGL0J04818g
Dictyostelium discoideum (Ddi) ddi11397 DDB0191115
Debaryomyces hansenii (Dha) dha2781 DEHA0D10912g
Drosophila melanogaster (Dme) dme3526 CG9446-PA
(FBgn0033109)
Drosophila melanogaster (Dme) dme3528 CG9446-PB
(FBgn0033109)
Drosophila melanogaster (Dme) dme3527 CG9446-PC
(FBgn0033109)
Danio rerio (Dre) dre21086 ENSDARP00000007696
(LOC560168)
Danio rerio (Dre) dre19024 ENSDARP00000019172
Danio rerio (Dre) dre31403 ENSDARP00000026454
(coro1c)		 Q7ZW06
Danio rerio (Dre) dre31404 ENSDARP00000039795
(LOC562849)
Danio rerio (Dre) dre21087 ENSDARP00000045879
(zgc:63634)		 Q7SZ58
Takifugu rubripes (Fru) fru28879 SINFRUP00000130259
Takifugu rubripes (Fru) fru8191 SINFRUP00000145769
Takifugu rubripes (Fru) fru11643 SINFRUP00000150127
Takifugu rubripes (Fru) fru8563 SINFRUP00000158926
Takifugu rubripes (Fru) fru10202 SINFRUP00000168484
Gallus gallus (Gga) gga7296 ENSGALP00000007822
(RCJMB04_2p8)		 Q5ZI60
Gallus gallus (Gga) gga7298 ENSGALP00000007824
(RCJMB04_2p8)
Homo sapiens (Hsa) hsa11987 ENSP00000219150
(CORO1A)		 P31146
Homo sapiens (Hsa) hsa8134 ENSP00000261401
(CORO1C)		 Q9ULV4
Homo sapiens (Hsa) hsa6072 ENSP00000340211
(CORO1B)		 Q9BR76
Homo sapiens (Hsa) hsa11988 ENSP00000354705
Kluyveromyces lactis (Kla) kla2180 KLLA0D02530g
Mus musculus (Mmu) mmu20709 ENSMUSP00000004646
(MGI:1345964)		 Q9WUM4
Mus musculus (Mmu) mmu13067 ENSMUSP00000008893
(MGI:1345963)		 Q9WUM3
Mus musculus (Mmu) mmu4283 ENSMUSP00000021190
(MGI:2183448)		 Q920M5-1
Mus musculus (Mmu) mmu25094 ENSMUSP00000032949
(MGI:1345961)		 O89053
Mus musculus (Mmu) mmu4284 ENSMUSP00000056862
(MGI:2183448)		 Q920M5-4
Neurospora crassa (Ncr) ncr195 NCU00202.2
Plasmodium falciparum (Pfa) pfa5273 PFL2460w
Rattus norvegicus (Rno) rno8763 ENSRNOP00000000886
(RGD:1564490)		 B2RYG0
Rattus norvegicus (Rno) rno5666 ENSRNOP00000019759
(RGD:708560)		 Q920J3
Rattus norvegicus (Rno) rno2989 ENSRNOP00000026496
(RGD:620009)		 Q91ZN1
Rattus norvegicus (Rno) rno3435 ENSRNOP00000035020
(RGD:2382)		 O89046
Rattus norvegicus (Rno) rno5667 ENSRNOP00000044817
(RGD:708560)
Saccharomyces cerevisiae (Sce) sce4552 YLR429W
(S000004421)
Schizosaccharomyces pombe (Spo) spo3282 SPAC23C4.02 O13923
Yarrowia lipolytica (Yli) yli659 YALI0A19470g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0001772 immunological synapse C
IDA
MmuMGI:1345961
GO:0005575 cellular_component C
ND
MmuMGI:2183448
MGI:1345963
PfaPFL2460w
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC23C4.02
GO:0005856 cytoskeleton C
TAS
MmuMGI:1345964
GO:0005885 Arp2/3 protein complex C
IDA
SceS000004421
IPI
SceS000004421
GO:0005886 plasma membrane C
IDA
MmuMGI:1345961
MGI:1345961
GO:0015629 actin cytoskeleton C
IDA
MmuMGI:1345961
NAS
DmeFBgn0033109
GO:0030479 actin cortical patch C
IDA
SceS000004421
SpoSPAC23C4.02
GO:0031252 cell leading edge C
IDA
MmuMGI:1345961
GO:0043234 protein complex C
NAS
SpoSPAC23C4.02
GO:0003674 molecular_function F
ND
MmuMGI:2183448
GO:0003779 actin binding F
ISS
DmeFBgn0033109
PfaPFL2460w
SpoSPAC23C4.02
GO:0005515 protein binding F
IPI
MmuMGI:1345963
MGI:1345961
GO:0008017 microtubule binding F
IDA
SceS000004421
GO:0008092 cytoskeletal protein binding F
IMP
MmuMGI:1345961
GO:0030674 protein binding, bridging F
IDA
SceS000004421
GO:0042802 identical protein binding F
IGI
MmuMGI:1345961
GO:0051015 actin filament binding F
IDA
MmuMGI:1345961
SceS000004421
GO:0000003 reproduction P
IMP
CelWBGene00000768
GO:0000147 actin cortical patch assembly P
TAS
MmuMGI:1345964
GO:0000910 cytokinesis P
ISS
PfaPFL2460w
GO:0006415 translational termination P
RCA
SceS000004421
GO:0006816 calcium ion transport P
IMP
MmuMGI:1345961
GO:0006909 phagocytosis P
TAS
MmuMGI:1345964
GO:0006928 cellular component movement P
ISS
PfaPFL2460w
GO:0007015 actin filament organization P
IMP
MmuMGI:1345961
SceS000004421
IPI
SceS000004421
GO:0007017 microtubule-based process P
IPI
SceS000004421
ISS
PfaPFL2460w
GO:0007126 meiosis P
IMP
CelWBGene00000768
GO:0008064 regulation of actin polymerization or
depolymerization		 P
IMP
MmuMGI:1345961
GO:0008150 biological_process P
ND
MmuMGI:2183448
MGI:1345963
GO:0008360 regulation of cell shape P
IMP
MmuMGI:1345961
GO:0016477 cell migration P
IMP
MmuMGI:1345961
GO:0030036 actin cytoskeleton organization P
ISS
SpoSPAC23C4.02
TAS
MmuMGI:1345964
GO:0030041 actin filament polymerization P
NAS
SpoSPAC23C4.02
GO:0030335 positive regulation of cell migration P
IMP
MmuMGI:1345961
GO:0030595 leukocyte chemotaxis P
IMP
MmuMGI:1345961
GO:0030833 regulation of actin filament polymerization P
IMP
MmuMGI:1345961
GO:0032796 uropod organization P
IMP
MmuMGI:1345961
GO:0034097 response to cytokine stimulus P
IMP
MmuMGI:1345961
GO:0034316 negative regulation of Arp2/3 complex-mediated
actin nucleation		 P
IDA
SceS000004421
IMP
SceS000004421
GO:0042102 positive regulation of T cell proliferation P
IMP
MmuMGI:1345961
GO:0043029 T cell homeostasis P
IMP
MmuMGI:1345961
GO:0048873 homeostasis of number of cells within a
tissue		 P
IMP
MmuMGI:1345961
GO:0050870 positive regulation of T cell activation P
IMP
MmuMGI:1345961
GO:0051017 actin filament bundle assembly P
TAS
SpoSPAC23C4.02
GO:0051049 regulation of transport P
RCA
SceS000004421
GO:0051666 actin cortical patch localization P
IMP
SceS000004421

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC23C4.02
(O13923)		 YLR429W
(S000004421)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC23C4.02
GO:0005885 Arp2/3 protein complex C
IDA
SceS000004421
IPI
SceS000004421
GO:0030479 actin cortical patch C
IDA
SceS000004421
SpoSPAC23C4.02
GO:0043234 protein complex C
NAS
SpoSPAC23C4.02
GO:0003779 actin binding F
ISS
SpoSPAC23C4.02
GO:0008017 microtubule binding F
IDA
SceS000004421
GO:0030674 protein binding, bridging F
IDA
SceS000004421
GO:0051015 actin filament binding F
IDA
SceS000004421
GO:0006415 translational termination P
RCA
SceS000004421
GO:0007015 actin filament organization P
IMP
SceS000004421
IPI
SceS000004421
GO:0007017 microtubule-based process P
IPI
SceS000004421
GO:0030036 actin cytoskeleton organization P
ISS
SpoSPAC23C4.02
GO:0030041 actin filament polymerization P
NAS
SpoSPAC23C4.02
GO:0034316 negative regulation of Arp2/3 complex-mediated
actin nucleation		 P
IDA
SceS000004421
IMP
SceS000004421
GO:0051017 actin filament bundle assembly P
TAS
SpoSPAC23C4.02
GO:0051049 regulation of transport P
RCA
SceS000004421
GO:0051666 actin cortical patch localization P
IMP
SceS000004421

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Query species:

Include wild-cards:   

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GO info in one table:

s.khadayate@ucl.ac.uk