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Search term: YLR449W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name FPR4
SGD link S000004441
Alternative ID YLR449W
Description Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones
Synonyms YLR449W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0552 A-D-YP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING FKBP-type peptidyl-prolyl cis-trans isomerase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g18170 GI:18394580
Arabidopsis thaliana (Ath) At1g20810 GI:15218039
Arabidopsis thaliana (Ath) At1g73650_1 GI:12324200
Arabidopsis thaliana (Ath) At2g43560 GI:15224305
Arabidopsis thaliana (Ath) At3g10060 GI:15232828
Arabidopsis thaliana (Ath) At3g12340 GI:15230464
Arabidopsis thaliana (Ath) At4g19830 GI:15235203
Arabidopsis thaliana (Ath) At4g25340 GI:7487577
Arabidopsis thaliana (Ath) At5g05420 GI:15239110
Arabidopsis thaliana (Ath) At5g13410 GI:15240623
Drosophila melanogaster (Dme) 7300000 GI:7300000
Saccharomyces cerevisiae (Sce) YLR449w
(S000004441)
GI:6323482 Q06205
Saccharomyces cerevisiae (Sce) YML074c
(S000004539)
GI:6323566 P38911
Schizosaccharomyces pombe (Spo) SPAC27F1.06c GI:19115447 Q10175
Schizosaccharomyces pombe (Spo) SPBC1347.02 GI:19113486 O74191
Arabidopsis thaliana (Ath) At1g18170 GI:18394580
Arabidopsis thaliana (Ath) At1g20810 GI:15218039
Arabidopsis thaliana (Ath) At1g73650_1 GI:12324200
Arabidopsis thaliana (Ath) At2g43560 GI:15224305
Arabidopsis thaliana (Ath) At3g10060 GI:15232828
Arabidopsis thaliana (Ath) At3g12340 GI:15230464
Arabidopsis thaliana (Ath) At4g19830 GI:15235203
Arabidopsis thaliana (Ath) At4g25340 GI:7487577
Arabidopsis thaliana (Ath) At5g05420 GI:15239110
Arabidopsis thaliana (Ath) At5g13410 GI:15240623
Drosophila melanogaster (Dme) 7300000 GI:7300000
Saccharomyces cerevisiae (Sce) YLR449w
(S000004441)
GI:6323482 Q06205
Saccharomyces cerevisiae (Sce) YML074c
(S000004539)
GI:6323566 P38911
Schizosaccharomyces pombe (Spo) SPAC27F1.06c GI:19115447 Q10175
Schizosaccharomyces pombe (Spo) SPBC1347.02 GI:19113486 O74191


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
SceS000004441
GO:0005634 nucleus C
IDA
AthAt4g25340
SceS000004441
GO:0005730 nucleolus C
IDA
AthAt4g25340
SceS000004539
SpoSPBC1347.02
SPAC27F1.06c
RCA
SceS000004441
GO:0005773 vacuole C
IDA
AthAt1g73650
GO:0005886 plasma membrane C
IDA
AthAt1g73650
GO:0009507 chloroplast C
IDA
AthAt1g20810
At1g18170
At5g13410
At3g10060
At2g43560
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt5g13410
At3g10060
At1g18170
GO:0009543 chloroplast thylakoid lumen C
IDA
AthAt3g10060
At5g13410
At2g43560
At1g20810
ISS
AthAt5g05420
At2g43560
At3g10060
At5g13410
At1g20810
At3g12340
At4g19830
GO:0009579 thylakoid C
IDA
AthAt5g13410
At3g10060
At2g43560
GO:0031977 thylakoid lumen C
IDA
AthAt2g43560
At1g20810
At5g13410
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
SceS000004539
S000004441
ISS
AthAt1g20810
At5g05420
At4g19830
At4g25340
At3g12340
At2g43560
At1g18170
At5g13410
At3g10060
GO:0005527 macrolide binding F
IDA
SceS000004539
S000004441
GO:0005528 FK506 binding F
ISS
AthAt1g18170
At5g05420
At1g20810
At5g13410
At3g10060
At4g25340
At2g43560
At4g19830
At3g12340
GO:0042393 histone binding F
IDA
AthAt4g25340
SceS000004441
GO:0000183 chromatin silencing at rDNA P
IMP
SceS000004441
GO:0000412 histone peptidyl-prolyl isomerization P
IDA
SceS000004441
GO:0000415 negative regulation of histone H3-K36
methylation
P
IMP
SceS000004441
GO:0006334 nucleosome assembly P
IDA
SceS000004441
IMP
AthAt4g25340
GO:0006457 protein folding P
NAS
SpoSPAC27F1.06c
SPBC1347.02
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IGI
SceS000004441
IMP
SceS000004441
GO:0051598 meiotic recombination checkpoint P
IDA
SceS000004539
IMP
SceS000004539

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_5291

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago2654 AER150W
Arabidopsis thaliana (Ath) ath20514 At4g25340.1
Candida glabrata (Cgl) cgl4575 CAGL0L11484g
Candida glabrata (Cgl) cgl4683 CAGL0M00638g
Cryptococcus neoformans (Cne) cne607 163.m02744
Dictyostelium discoideum (Ddi) ddi7932 DDB0186469
Debaryomyces hansenii (Dha) dha2754 DEHA0D10329g
Drosophila melanogaster (Dme) dme12741 CG6226-PA
(FBgn0013269)
Kluyveromyces lactis (Kla) kla739 KLLA0B04664g
Neurospora crassa (Ncr) ncr3141 NCU03241.2
Oryza sativa (Osa) osa84633 8274.m00137
Saccharomyces cerevisiae (Sce) sce4574 YLR449W
(S000004441)
Saccharomyces cerevisiae (Sce) sce4678 YML074C
(S000004539)
Schizosaccharomyces pombe (Spo) spo3557 SPAC27F1.06c Q10175
Schizosaccharomyces pombe (Spo) spo3727 SPBC1347.02 O74191
Yarrowia lipolytica (Yli) yli5009 YALI0E27808g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
SceS000004441
GO:0005634 nucleus C
IDA
AthAt4g25340
SceS000004441
ISS
DmeFBgn0013269
NAS
DmeFBgn0013269
GO:0005730 nucleolus C
IDA
AthAt4g25340
SceS000004539
SpoSPBC1347.02
SPAC27F1.06c
RCA
SceS000004441
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0013269
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
SceS000004539
S000004441
ISS
AthAt4g25340
DmeFBgn0013269
NAS
DmeFBgn0013269
GO:0005527 macrolide binding F
IDA
SceS000004539
S000004441
GO:0005528 FK506 binding F
IDA
DmeFBgn0013269
ISS
AthAt4g25340
DmeFBgn0013269
NAS
DmeFBgn0013269
GO:0042393 histone binding F
IDA
AthAt4g25340
SceS000004441
GO:0000183 chromatin silencing at rDNA P
IMP
SceS000004441
GO:0000412 histone peptidyl-prolyl isomerization P
IDA
SceS000004441
GO:0000415 negative regulation of histone H3-K36
methylation
P
IMP
SceS000004441
GO:0006334 nucleosome assembly P
IDA
SceS000004441
IMP
AthAt4g25340
GO:0006457 protein folding P
ISS
DmeFBgn0013269
NAS
DmeFBgn0013269
SpoSPAC27F1.06c
SPBC1347.02
GO:0010507 negative regulation of autophagy P
IMP
DmeFBgn0013269
GO:0016242 negative regulation of macroautophagy P
IMP
DmeFBgn0013269
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IGI
SceS000004441
IMP
SceS000004441
GO:0051598 meiotic recombination checkpoint P
IDA
SceS000004539
IMP
SceS000004539

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC27F1.06c
(Q10175)
YLR449W
(S000004441)
SPBC1347.02
(O74191)
YLR449W
(S000004441)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
SceS000004441
GO:0005634 nucleus C
IDA
SceS000004441
GO:0005730 nucleolus C
IDA
SpoSPBC1347.02
SPAC27F1.06c
RCA
SceS000004441
GO:0003755 peptidyl-prolyl cis-trans isomerase
activity
F
IDA
SceS000004441
GO:0005527 macrolide binding F
IDA
SceS000004441
GO:0042393 histone binding F
IDA
SceS000004441
GO:0000183 chromatin silencing at rDNA P
IMP
SceS000004441
GO:0000412 histone peptidyl-prolyl isomerization P
IDA
SceS000004441
GO:0000415 negative regulation of histone H3-K36
methylation
P
IMP
SceS000004441
GO:0006334 nucleosome assembly P
IDA
SceS000004441
GO:0006457 protein folding P
NAS
SpoSPAC27F1.06c
SPBC1347.02
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IGI
SceS000004441
IMP
SceS000004441

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GO info in one table:

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