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Search term: YLR452C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SST2
SGD link S000004444
Alternative ID YLR452C
Description GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family
Synonyms YLR452C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39822

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SST2
(S000004444)		 GI:6323485
Kluyveromyces lactis (Kla) KLLA0D10549g GI:50307105
Eremothecium gossypii (Ego) AGOS_ABR176C GI:45185407


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005886 plasma membrane C
IDA
SceS000004444
GO:0005096 GTPase activator activity F
IDA
SceS000004444
GO:0000746 conjugation P
RCA
SceS000004444
GO:0000754 adaptation of signaling pathway by response to
pheromone involved in conjugation with cellular
fusion		 P
IMP
SceS000004444
TAS
SceS000004444
GO:0006414 translational elongation P
RCA
SceS000004444
GO:0007165 signal transduction P
IMP
SceS000004444
GO:0009966 regulation of signal transduction P
RCA
SceS000004444
GO:0019236 response to pheromone P
RCA
SceS000004444
GO:0019953 sexual reproduction P
RCA
SceS000004444
GO:0051098 regulation of binding P
RCA
SceS000004444

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11569

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago769 ABR176C
Candida glabrata (Cgl) cgl2079 CAGL0H00374g
Cryptococcus neoformans (Cne) cne1920 181.m07892
Debaryomyces hansenii (Dha) dha3714 DEHA0E10692g
Kluyveromyces lactis (Kla) kla2530 KLLA0D10549g
Neurospora crassa (Ncr) ncr8108 NCU08319.2
Saccharomyces cerevisiae (Sce) sce4577 YLR452C
(S000004444)
Schizosaccharomyces pombe (Spo) spo2185 SPAC22F3.12c Q09777
Yarrowia lipolytica (Yli) yli3454 YALI0D18018g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC22F3.12c
GO:0005737 cytoplasm C
IDA
SpoSPAC22F3.12c
GO:0005829 cytosol C
IDA
SpoSPAC22F3.12c
GO:0005886 plasma membrane C
IDA
SceS000004444
ISS
SpoSPAC22F3.12c
GO:0005096 GTPase activator activity F
IDA
SceS000004444
ISS
SpoSPAC22F3.12c
GO:0000746 conjugation P
RCA
SceS000004444
GO:0000754 adaptation of signaling pathway by response to
pheromone involved in conjugation with cellular
fusion		 P
IMP
SceS000004444
TAS
SceS000004444
GO:0006414 translational elongation P
RCA
SceS000004444
GO:0007165 signal transduction P
IMP
SceS000004444
GO:0009966 regulation of signal transduction P
RCA
SceS000004444
GO:0010969 regulation of pheromone-dependent signal
transduction involved in conjugation with cellular
fusion		 P
IMP
SpoSPAC22F3.12c
GO:0019236 response to pheromone P
RCA
SceS000004444
GO:0019953 sexual reproduction P
RCA
SceS000004444
GO:0051098 regulation of binding P
RCA
SceS000004444
GO:0090029 negative regulation of pheromone-dependent signal
transduction involved in conjugation with cellular
fusion		 P
IMP
SpoSPAC22F3.12c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC22F3.12c
(Q09777)		 YLR452C
(S000004444)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC22F3.12c
GO:0005737 cytoplasm C
IDA
SpoSPAC22F3.12c
GO:0005829 cytosol C
IDA
SpoSPAC22F3.12c
GO:0005886 plasma membrane C
IDA
SceS000004444
ISS
SpoSPAC22F3.12c
GO:0005096 GTPase activator activity F
IDA
SceS000004444
ISS
SpoSPAC22F3.12c
GO:0000746 conjugation P
RCA
SceS000004444
GO:0000754 adaptation of signaling pathway by response to
pheromone involved in conjugation with cellular
fusion		 P
IMP
SceS000004444
TAS
SceS000004444
GO:0006414 translational elongation P
RCA
SceS000004444
GO:0007165 signal transduction P
IMP
SceS000004444
GO:0009966 regulation of signal transduction P
RCA
SceS000004444
GO:0010969 regulation of pheromone-dependent signal
transduction involved in conjugation with cellular
fusion		 P
IMP
SpoSPAC22F3.12c
GO:0019236 response to pheromone P
RCA
SceS000004444
GO:0019953 sexual reproduction P
RCA
SceS000004444
GO:0051098 regulation of binding P
RCA
SceS000004444
GO:0090029 negative regulation of pheromone-dependent signal
transduction involved in conjugation with cellular
fusion		 P
IMP
SpoSPAC22F3.12c

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