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Search term: YML008C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERG6
SGD link S000004467
Alternative ID YML008C
Description Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to both lipid particles and mitochondrial outer membrane
Synonyms YML008C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1269 AC--YP-

KOGs classification KOGs description
METABOLISMPOORLY CHARACTERIZED SAM-dependent methyltransferases

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g20330 GI:15217917
Arabidopsis thaliana (Ath) At1g48600 GI:15221909
Arabidopsis thaliana (Ath) At1g64970 GI:15217804
Arabidopsis thaliana (Ath) At1g73600 GI:15219502
Arabidopsis thaliana (Ath) At1g76090 GI:15222955
Arabidopsis thaliana (Ath) At3g01660 GI:15232158
Arabidopsis thaliana (Ath) At3g17990 GI:15229562
Arabidopsis thaliana (Ath) At3g18000 GI:15229566
Arabidopsis thaliana (Ath) At5g13710 GI:15240691
Caenorhabditis elegans (Cel) CE05100 GI:17537907
Caenorhabditis elegans (Cel) CE11068
(WBGene00018811)		 GI:17561380 Q22993
Caenorhabditis elegans (Cel) CE12180
(WBGene00019675)		 GI:17562552 P91387
Caenorhabditis elegans (Cel) CE12576
(WBGene00019963)		 GI:17562972 O01593
Caenorhabditis elegans (Cel) CE12586
(WBGene00019968)		 GI:17562982 O01889
Caenorhabditis elegans (Cel) CE20965 GI:17553890
Caenorhabditis elegans (Cel) CE27431 GI:17562968
Caenorhabditis elegans (Cel) CE29162 GI:17537905 Q95PW7
Saccharomyces cerevisiae (Sce) YML008c
(S000004467)		 GI:6323635 P25087
Schizosaccharomyces pombe (Spo) SPAC1B3.06c GI:19115702 O13871
Schizosaccharomyces pombe (Spo) SPBC16E9.05 GI:19112579 O14321


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g01660
GO:0005634 nucleus C
IDA
SpoSPAC1B3.06c
SPBC16E9.05
GO:0005737 cytoplasm C
ISS
AthAt3g18000
GO:0005739 mitochondrion C
IDA
SceS000004467
GO:0005741 mitochondrial outer membrane C
IDA
SceS000004467
GO:0005773 vacuole C
IDA
AthAt5g13710
GO:0005783 endoplasmic reticulum C
IDA
AthAt1g20330
ISS
SpoSPBC16E9.05
TAS
AthAt1g76090
At1g20330
SceS000004467
GO:0005811 lipid particle C
IDA
SceS000004467
GO:0005829 cytosol C
IDA
SpoSPAC1B3.06c
GO:0009507 chloroplast C
ISS
AthAt1g64970
GO:0000234 phosphoethanolamine N-methyltransferase
activity		 F
IGI
AthAt3g18000
ISS
AthAt1g48600
At1g73600
At3g18000
GO:0003838 sterol 24-C-methyltransferase activity F
IDA
AthAt5g13710
SceS000004467
IGI
AthAt5g13710
ISS
SpoSPBC16E9.05
TAS
AthAt1g76090
GO:0008168 methyltransferase activity F
ISS
AthAt3g18000
GO:0008757 S-adenosylmethionine-dependent methyltransferase
activity		 F
IDA
AthAt1g20330
ISS
AthAt1g76090
GO:0050342 tocopherol O-methyltransferase
activity		 F
IDA
AthAt1g64970
GO:0006066 alcohol metabolic process P
RCA
SceS000004467
GO:0006656 phosphatidylcholine biosynthetic
process		 P
IGI
AthAt3g18000
GO:0006696 ergosterol biosynthetic process P
IMP
SpoSPBC16E9.05
ISS
SpoSPBC16E9.05
TAS
SceS000004467
GO:0007389 pattern specification process P
IMP
AthAt1g20330
GO:0009555 pollen development P
IMP
AthAt3g18000
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt5g13710
GO:0009825 multidimensional cell growth P
IMP
AthAt1g20330
GO:0009826 unidimensional cell growth P
IMP
AthAt3g18000
GO:0009860 pollen tube growth P
IMP
AthAt3g18000
GO:0010051 xylem and phloem pattern formation P
IMP
AthAt1g20330
GO:0010183 pollen tube guidance P
IMP
AthAt3g18000
GO:0010189 vitamin E biosynthetic process P
IMP
AthAt1g64970
GO:0016126 sterol biosynthetic process P
IDA
AthAt1g20330
IMP
AthAt5g13710
TAS
AthAt5g13710
At1g76090
GO:0032259 methylation P
ISS
SpoSPBC16E9.05
GO:0032876 negative regulation of DNA endoreduplication P
IMP
AthAt1g20330
GO:0033554 cellular response to stress P
IEP
SpoSPAC1B3.06c
GO:0042425 choline biosynthetic process P
IMP
AthAt3g18000
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004467
GO:0048528 post-embryonic root development P
IMP
AthAt3g18000
GO:0071210 protein insertion into membrane
raft		 P
IMP
SpoSPBC16E9.05
GO:0090002 establishment of protein localization in plasma
membrane		 P
IMP
SpoSPBC16E9.05

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39875

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) erg6
(SPBC16E9.05)		 GI:19112579 O14321
Saccharomyces cerevisiae (Sce) ERG6
(S000004467)		 GI:6323635 P25087
Kluyveromyces lactis (Kla) KLLA0A01738g GI:50302283
Eremothecium gossypii (Ego) AGOS_ADR196W GI:45188069
Magnaporthe grisea (Mgr) MGG_10568 GI:39969919
Neurospora crassa (Ncr) NCU03006.1 GI:32419499
Arabidopsis thaliana (Ath) SMT1 GI:145334395
Oryza sativa (Osa) Os07g0206700 GI:115471111


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthSMT1
GO:0005634 nucleus C
IDA
SpoSPBC16E9.05
GO:0005739 mitochondrion C
IDA
SceS000004467
GO:0005741 mitochondrial outer membrane C
IDA
SceS000004467
GO:0005773 vacuole C
IDA
AthSMT1
GO:0005783 endoplasmic reticulum C
ISS
SpoSPBC16E9.05
TAS
SceS000004467
GO:0005811 lipid particle C
IDA
SceS000004467
GO:0003838 sterol 24-C-methyltransferase activity F
IDA
AthSMT1
SceS000004467
IGI
AthSMT1
ISS
SpoSPBC16E9.05
GO:0008757 S-adenosylmethionine-dependent methyltransferase
activity		 F
IDA
AthSMT1
GO:0006066 alcohol metabolic process P
RCA
SceS000004467
GO:0006696 ergosterol biosynthetic process P
IMP
SpoSPBC16E9.05
ISS
SpoSPBC16E9.05
TAS
SceS000004467
GO:0006952 defense response P
IEP
AthSMT1
GO:0009611 response to wounding P
IEP
AthSMT1
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthSMT1
GO:0016126 sterol biosynthetic process P
IMP
AthSMT1
TAS
AthSMT1
GO:0032259 methylation P
ISS
SpoSPBC16E9.05
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004467
GO:0051707 response to other organism P
IEP
AthSMT1
GO:0071210 protein insertion into membrane
raft		 P
IMP
SpoSPBC16E9.05
GO:0090002 establishment of protein localization in plasma
membrane		 P
IMP
SpoSPBC16E9.05

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3933

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1937 ADR196W
Arabidopsis thaliana (Ath) ath23566 At5g13710.1
Caenorhabditis elegans (Cel) cel9672 F49C12.10
(CE03370;
WBGene00009879)
Caenorhabditis elegans (Cel) cel11319 H14E04.1
(CE29973;
WBGene00019198)
Candida glabrata (Cgl) cgl2264 CAGL0H04653g
Cryptococcus neoformans (Cne) cne4848 186.m03744
Dictyostelium discoideum (Ddi) ddi7219 DDB0188166
Debaryomyces hansenii (Dha) dha3156 DEHA0D19151g
Kluyveromyces lactis (Kla) kla73 KLLA0A01738g
Neurospora crassa (Ncr) ncr2911 NCU03006.2
Oryza sativa (Osa) osa63298 6728.m00183
Oryza sativa (Osa) osa81523 8219.m00097
Saccharomyces cerevisiae (Sce) sce4604 YML008C
(S000004467)
Schizosaccharomyces pombe (Spo) spo4908 SPBC16E9.05 O14321
Yarrowia lipolytica (Yli) yli5709 YALI0F08701g