YOGY Home YOGY Help

Search term: YML013W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name UBX2
SGD link S000004475
Alternative ID YML013W
Description Protein involved in ER-associated protein degradation; proposed to coordinate the assembly of proteins involved in ERAD; contains a UBX (ubiquitin regulatory X) domain and a ubiquitin-associated (UBA) domain
Synonyms YML013W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1363 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Predicted regulator of the ubiquitin pathway (contains UAS and UBX domains)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g10790 GI:15236931
Arabidopsis thaliana (Ath) At4g11740 GI:7487672
Arabidopsis thaliana (Ath) At4g23040 GI:7486575
Caenorhabditis elegans (Cel) CE04118_1 GI:17550674
Caenorhabditis elegans (Cel) CE10730
(WBGene00018586)
GI:17534191
Drosophila melanogaster (Dme) 7298477
(FBgn0005632)
GI:17137596
Drosophila melanogaster (Dme) 7303003 GI:20130031 Q7JUP3
Homo sapiens (Hsa) Hs19528655 GI:19528655
Homo sapiens (Hsa) Hs5031651
(UBXN8)
GI:5031651 O00124
Homo sapiens (Hsa) Hs5901948
(FAF1)
GI:5901948 Q9UNN5
Saccharomyces cerevisiae (Sce) YDL091c
(S000002249)
GI:6320112 Q12229
Saccharomyces cerevisiae (Sce) YML013w
(S000004475)
GI:6323628 Q04228
Schizosaccharomyces pombe (Spo) SPCC285.11 GI:19075839 O74498


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000837 Doa10p ubiquitin ligase complex C
IDA
SceS000004475
GO:0005575 cellular_component C
ND
AthAt4g10790
GO:0005634 nucleus C
IDA
AthAt4g11740
HsaFAF1
GO:0005737 cytoplasm C
IDA
DmeFBgn0005632
SceS000002249
GO:0005741 mitochondrial outer membrane C
IDA
SceS000004475
GO:0005783 endoplasmic reticulum C
IDA
SceS000004475
SpoSPCC285.11
ISS
SpoSPCC285.11
GO:0005829 cytosol C
IDA
AthAt4g23040
At4g11740
HsaFAF1
GO:0030176 integral to endoplasmic reticulum
membrane
C
IDA
SceS000004475
GO:0031265 CD95 death-inducing signaling complex C
NAS
HsaFAF1
GO:0048471 perinuclear region of cytoplasm C
IDA
HsaFAF1
GO:0003674 molecular_function F
ND
AthAt4g23040
SceS000002249
SpoSPCC285.11
GO:0004843 ubiquitin-specific protease activity F
NAS
DmeFBgn0005632
TAS
DmeFBgn0005632
GO:0005515 protein binding F
IPI
HsaFAF1
GO:0019887 protein kinase regulator activity F
NAS
HsaFAF1
GO:0019901 protein kinase binding F
IDA
HsaFAF1
GO:0030674 protein binding, bridging F
IPI
SceS000004475
GO:0031072 heat shock protein binding F
IDA
HsaFAF1
GO:0051059 NF-kappaB binding F
IPI
HsaFAF1
GO:0006511 ubiquitin-dependent protein catabolic
process
P
IGI
DmeFBgn0005632
GO:0006897 endocytosis P
NAS
DmeFBgn0005632
GO:0007097 nuclear migration P
IMP
DmeFBgn0005632
GO:0007253 cytoplasmic sequestering of NF-kappaB P
IMP
HsaFAF1
GO:0007338 single fertilization P
TAS
HsaUBXN8
GO:0007349 cellularization P
IMP
DmeFBgn0005632
GO:0008150 biological_process P
ND
AthAt4g23040
At4g10790
SceS000002249
GO:0008219 cell death P
IMP
HsaFAF1
GO:0008354 germ cell migration P
TAS
DmeFBgn0005632
GO:0008583 mystery cell fate differentiation P
IMP
DmeFBgn0005632
TAS
DmeFBgn0005632
GO:0009306 protein secretion P
IMP
SceS000004475
GO:0009790 embryo development P
IMP
DmeFBgn0005632
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00018586
GO:0016192 vesicle-mediated transport P
TAS
AthAt4g11740
GO:0016579 protein deubiquitination P
IDA
DmeFBgn0005632
IMP
DmeFBgn0005632
NAS
DmeFBgn0005632
TAS
DmeFBgn0005632
GO:0030433 ER-associated protein catabolic
process
P
IMP
SceS000004475
IPI
SceS000004475
GO:0031334 positive regulation of protein complex
assembly
P
IMP
HsaFAF1
GO:0033554 cellular response to stress P
IEP
SpoSPCC285.11
GO:0042176 regulation of protein catabolic
process
P
IMP
HsaFAF1
GO:0043065 positive regulation of apoptosis P
NAS
HsaFAF1
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
IMP
SceS000004475
ISS
SpoSPCC285.11
NAS
HsaFAF1
GO:0045861 negative regulation of proteolysis P
NAS
DmeFBgn0005632
GO:0048749 compound eye development P
IMP
DmeFBgn0005632

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39872

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) UBX2
(S000004475)
GI:6323628 Q04228
Kluyveromyces lactis (Kla) KLLA0B01001g GI:50303267
Eremothecium gossypii (Ego) AGOS_ADR182W GI:45188055


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000837 Doa10p ubiquitin ligase complex C
IDA
SceS000004475
GO:0005741 mitochondrial outer membrane C
IDA
SceS000004475
GO:0005783 endoplasmic reticulum C
IDA
SceS000004475
GO:0030176 integral to endoplasmic reticulum
membrane
C
IDA
SceS000004475
GO:0030674 protein binding, bridging F
IPI
SceS000004475
GO:0009306 protein secretion P
IMP
SceS000004475
GO:0030433 ER-associated protein catabolic
process
P
IMP
SceS000004475
IPI
SceS000004475
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
IMP
SceS000004475

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24767

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago1923 ADR182W
Candida glabrata (Cgl) cgl2270 CAGL0H04785g
Debaryomyces hansenii (Dha) dha3648 DEHA0E09185g
Kluyveromyces lactis (Kla) kla573 KLLA0B01001g
Saccharomyces cerevisiae (Sce) sce4612 YML013W
(S000004475)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000837 Doa10p ubiquitin ligase complex C
IDA
SceS000004475
GO:0005741 mitochondrial outer membrane C
IDA
SceS000004475
GO:0005783 endoplasmic reticulum C
IDA
SceS000004475
GO:0030176 integral to endoplasmic reticulum
membrane
C
IDA
SceS000004475
GO:0030674 protein binding, bridging F
IPI
SceS000004475
GO:0009306 protein secretion P
IMP
SceS000004475
GO:0030433 ER-associated protein catabolic
process
P
IMP
SceS000004475
IPI
SceS000004475
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process
P
IMP
SceS000004475

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC285.11
(O74498)
YML013W
(S000004475)