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Search term: YML035C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name AMD1
SGD link S000004498
Alternative ID YML035C
Description AMP deaminase, tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; may be involved in regulation of intracellular adenine nucleotide pools
Synonyms YML035C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1096 ACDHYP-

KOGs classification KOGs description
METABOLISM Adenosine monophosphate deaminase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g38280 GI:7484807
Caenorhabditis elegans (Cel) CE04164 GI:17532315
Caenorhabditis elegans (Cel) CE27744 GI:17532313
Drosophila melanogaster (Dme) 7292938 GI:7292938
Homo sapiens (Hsa) Hs4557311
(AMPD1)		 GI:4557311 P23109
Homo sapiens (Hsa) Hs4502079
(AMPD3)		 GI:4502079 Q01432
Homo sapiens (Hsa) Hs21264318 GI:12644375 Q01433
Homo sapiens (Hsa) HsM19923098 GI:19923098
Saccharomyces cerevisiae (Sce) YBR284w GI:6319761 P38150
Saccharomyces cerevisiae (Sce) YJL070c GI:6322391 P40361
Saccharomyces cerevisiae (Sce) YML035c
(S000004498)		 GI:6323606 P15274
Schizosaccharomyces pombe (Spo) SPBC106.04 GI:19111945 P50998
Arabidopsis thaliana (Ath) At2g38280 GI:7484807
Caenorhabditis elegans (Cel) CE04164 GI:17532315
Caenorhabditis elegans (Cel) CE27744 GI:17532313
Drosophila melanogaster (Dme) 7292938 GI:7292938
Homo sapiens (Hsa) Hs4557311
(AMPD1)		 GI:4557311 P23109
Homo sapiens (Hsa) Hs4502079
(AMPD3)		 GI:4502079 Q01432
Homo sapiens (Hsa) Hs21264318 GI:12644375 Q01433
Homo sapiens (Hsa) HsM19923098 GI:19923098
Saccharomyces cerevisiae (Sce) YBR284w GI:6319761 P38150
Saccharomyces cerevisiae (Sce) YJL070c GI:6322391 P40361
Saccharomyces cerevisiae (Sce) YML035c
(S000004498)		 GI:6323606 P15274
Schizosaccharomyces pombe (Spo) SPBC106.04 GI:19111945 P50998


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceYBR284w
GO:0005634 nucleus C
IDA
AthAt2g38280
GO:0005737 cytoplasm C
IDA
SceS000004498
YJL070c
ISS
SpoSPBC106.04
GO:0005739 mitochondrion C
IDA
SceYJL070c
GO:0005792 microsome C
IDA
AthAt2g38280
GO:0005829 cytosol C
IDA
AthAt2g38280
SpoSPBC106.04
GO:0003674 molecular_function F
ND
SceYBR284w
YJL070c
GO:0003876 AMP deaminase activity F
IDA
SceS000004498
SpoSPBC106.04
IGI
AthAt2g38280
ISS
AthAt2g38280
GO:0006163 purine nucleotide metabolic process P
IC
SceS000004498
GO:0006188 IMP biosynthetic process P
ISS
SpoSPBC106.04
GO:0006196 AMP catabolic process P
TAS
HsaAMPD3
GO:0008150 biological_process P
ND
SceYBR284w
YJL070c
GO:0009168 purine ribonucleoside monophosphate biosynthetic
process		 P
ISS
AthAt2g38280
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt2g38280

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2979

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) AMPD2 GI:21264318
Canis familiaris (Cfa) AMPD2 GI:73959321
Mus musculus (Mmu) Ampd2
(MGI:88016)		 GI:21311925 Q9DBT5
Rattus norvegicus (Rno) Ampd2
(RGD:2110)		 GI:62644175
Drosophila melanogaster (Dme) CG32626
(FBgn0052626)		 GI:45551452
Anopheles gambiae (Aga) AgaP_AGAP000577 GI:158288649
Caenorhabditis elegans (Cel) C34F11.3
(CE33034;
WBGene00016415)		 GI:32564190
Schizosaccharomyces pombe (Spo) ada1
(SPBC106.04)		 GI:19111945 P50998
Saccharomyces cerevisiae (Sce) AMD1
(S000004498)		 GI:6323606 P15274
Kluyveromyces lactis (Kla) KLLA0D06171g GI:50306727
Eremothecium gossypii (Ego) AGOS_ABR204C GI:45185436
Magnaporthe grisea (Mgr) MGG_05630 GI:39941438
Neurospora crassa (Ncr) NCU02979.1 GI:32419447
Arabidopsis thaliana (Ath) FAC1 GI:30687456
Oryza sativa (Osa) Os07g0693500 GI:115474263
Plasmodium falciparum (Pfa) MAL13P1.146 GI:124513298


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
HsaAMPD2
MmuMGI:88016
GO:0005634 nucleus C
IDA
AthFAC1
GO:0005737 cytoplasm C
IDA
SceS000004498
ISS
SpoSPBC106.04
GO:0005792 microsome C
IDA
AthFAC1
GO:0005829 cytosol C
IDA
AthFAC1
SpoSPBC106.04
GO:0003674 molecular_function F
ND
MmuMGI:88016
GO:0003876 AMP deaminase activity F
IDA
SceS000004498
SpoSPBC106.04
IGI
AthFAC1
ISS
AthFAC1
DmeFBgn0052626
PfaMAL13P1.146
NAS
HsaAMPD2
GO:0005515 protein binding F
IPI
DmeFBgn0052626
GO:0002119 nematode larval development P
IMP
CelWBGene00016415
GO:0006163 purine nucleotide metabolic process P
IC
SceS000004498
NAS
HsaAMPD2
GO:0006188 IMP biosynthetic process P
ISS
SpoSPBC106.04
GO:0006196 AMP catabolic process P
ISS
PfaMAL13P1.146
GO:0008150 biological_process P
ND
MmuMGI:88016
GO:0009168 purine ribonucleoside monophosphate biosynthetic
process		 P
ISS
AthFAC1
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthFAC1
GO:0040007 growth P
IMP
CelWBGene00016415
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016415
GO:0040011 locomotion P
IMP
CelWBGene00016415

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_528

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15227 ENSANGP00000017310
Anopheles gambiae (Aga) aga15228 ENSANGP00000023647
Ashbya gossypii (Ago) ago798 ABR204C
Arabidopsis thaliana (Ath) ath10929 At2g38280.1
Arabidopsis thaliana (Ath) ath10930 At2g38280.2
Caenorhabditis elegans (Cel) cel3431 C34F11.3a
(CE33034;
WBGene00016415)
Caenorhabditis elegans (Cel) cel3432 C34F11.3b
(CE33035)
Candida glabrata (Cgl) cgl1945 CAGL0G07425g
Cryptococcus neoformans (Cne) cne5459 179.m00311
Dictyostelium discoideum (Ddi) ddi13623 DDB0191089
Debaryomyces hansenii (Dha) dha4213 DEHA0E22066g
Drosophila melanogaster (Dme) dme17764 CG32626-PA
(FBgn0052626)
Drosophila melanogaster (Dme) dme17765 CG32626-PB
(FBgn0052626)
Drosophila melanogaster (Dme) dme17763 CG32626-PC
(FBgn0052626)
Drosophila melanogaster (Dme) dme17766 CG32626-PD
(FBgn0052626)
Danio rerio (Dre) dre24592 ENSDARP00000011829
Danio rerio (Dre) dre4264 ENSDARP00000016754
Danio rerio (Dre) dre8917 ENSDARP00000024267
Danio rerio (Dre) dre24591 ENSDARP00000037627
Danio rerio (Dre) dre12020 ENSDARP00000042542
Danio rerio (Dre) dre12019 ENSDARP00000043969
Danio rerio (Dre) dre31901 ENSDARP00000045797
(LOC571355)		 Q3B749
Danio rerio (Dre) dre24593 ENSDARP00000047004
Takifugu rubripes (Fru) fru4317 SINFRUP00000136655
Takifugu rubripes (Fru) fru1452 SINFRUP00000136831
Takifugu rubripes (Fru) fru29932 SINFRUP00000145192
Takifugu rubripes (Fru) fru6733 SINFRUP00000148009
Gallus gallus (Gga) gga18767 ENSGALP00000009070
(AMPD3)
Homo sapiens (Hsa) hsa5194 ENSP00000256183
(AMPD3)		 Q01432-2
Homo sapiens (Hsa) hsa1642 ENSP00000256578
(AMPD2)		 Q01433-1
Homo sapiens (Hsa) hsa1641 ENSP00000345498
(AMPD2)		 Q01433-2
Homo sapiens (Hsa) hsa5195 ENSP00000349443
Homo sapiens (Hsa) hsa1643 ENSP00000351573
(AMPD2)		 Q01433-4
Kluyveromyces lactis (Kla) kla2336 KLLA0D06171g
Mus musculus (Mmu) mmu24896 ENSMUSP00000005829
(MGI:1096344)		 Q8CFR4
Mus musculus (Mmu) mmu17380 ENSMUSP00000029488
Mus musculus (Mmu) mmu24897 ENSMUSP00000063112
Mus musculus (Mmu) mmu17379 ENSMUSP00000077946
(MGI:88016)		 A2AE27
Neurospora crassa (Ncr) ncr2884 NCU02979.2
Oryza sativa (Osa) osa77236 7313.m00145
Plasmodium falciparum (Pfa) pfa3886 MAL13P1.146
Rattus norvegicus (Rno) rno2768 ENSRNOP00000024780
Rattus norvegicus (Rno) rno2767 ENSRNOP00000024933
(RGD:2111)		 O09178
Rattus norvegicus (Rno) rno16838 ENSRNOP00000026051
(RGD:2110)		 Q02356
Rattus norvegicus (Rno) rno16839 ENSRNOP00000050656
(RGD:2110)
Saccharomyces cerevisiae (Sce) sce4635 YML035C
(S000004498)
Schizosaccharomyces pombe (Spo) spo3967 SPBC106.04 P50998
Yarrowia lipolytica (Yli) yli4338 YALI0E11495g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:88016
GO:0005634 nucleus C
IDA
AthAt2g38280
GO:0005737 cytoplasm C
IDA
SceS000004498
ISS
SpoSPBC106.04
GO:0005792 microsome C
IDA
AthAt2g38280
GO:0005829 cytosol C
IDA
AthAt2g38280
SpoSPBC106.04
GO:0003674 molecular_function F
ND
MmuMGI:88016
GO:0003876 AMP deaminase activity F
IDA
SceS000004498
SpoSPBC106.04
IGI
AthAt2g38280
ISO
MmuMGI:1096344
ISS
AthAt2g38280
DmeFBgn0052626
PfaMAL13P1.146
GO:0005515 protein binding F
IPI
DmeFBgn0052626
GO:0002119 nematode larval development P
IMP
CelWBGene00016415
GO:0006163 purine nucleotide metabolic process P
IC
SceS000004498
GO:0006188 IMP biosynthetic process P
ISS
SpoSPBC106.04
GO:0006196 AMP catabolic process P
ISS
PfaMAL13P1.146
GO:0008150 biological_process P
ND
MmuMGI:88016
GO:0009168 purine ribonucleoside monophosphate biosynthetic
process		 P
ISS
AthAt2g38280
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt2g38280
GO:0040007 growth P
IMP
CelWBGene00016415
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00016415
GO:0040011 locomotion P
IMP
CelWBGene00016415

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC106.04
(P50998)		 YML035C
(S000004498)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000004498
ISS
SpoSPBC106.04
GO:0005829 cytosol C
IDA
SpoSPBC106.04
GO:0003876 AMP deaminase activity F
IDA
SceS000004498
SpoSPBC106.04
GO:0006163 purine nucleotide metabolic process P
IC
SceS000004498
GO:0006188 IMP biosynthetic process P
ISS
SpoSPBC106.04

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GO info in one table:

s.khadayate@ucl.ac.uk