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Search term: YML056C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name IMD4
SGD link S000004520
Alternative ID YML056C
Description Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
Synonyms YML056C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2550 ACDHYP-

KOGs classification KOGs description
METABOLISM IMP dehydrogenase/GMP reductase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g16350 GI:15219217
Arabidopsis thaliana (Ath) At1g79470 GI:15219385
Caenorhabditis elegans (Cel) CE09869
(WBGene00017984)		 GI:17560440 O16294
Caenorhabditis elegans (Cel) CE17247 GI:17542500
Drosophila melanogaster (Dme) 7291188 GI:17864202
Homo sapiens (Hsa) Hs11321611 GI:11321611
Homo sapiens (Hsa) Hs17445211 GI:17445211
Homo sapiens (Hsa) Hs18572586 GI:18572586
Homo sapiens (Hsa) Hs18576335 GI:18576335
Homo sapiens (Hsa) Hs18595147 GI:17481452
Homo sapiens (Hsa) Hs18595370 GI:18595370
Homo sapiens (Hsa) Hs20540918 GI:20540918
Homo sapiens (Hsa) Hs20555980 GI:20555980
Homo sapiens (Hsa) Hs20556041 GI:20556041
Homo sapiens (Hsa) Hs22044392 GI:22044392
Homo sapiens (Hsa) Hs22049703 GI:22049703
Homo sapiens (Hsa) Hs4504687 GI:4504687
Homo sapiens (Hsa) Hs4504689 GI:4504689
Homo sapiens (Hsa) Hs7706109 GI:7706109
Saccharomyces cerevisiae (Sce) YAR073w
(S000000095)		 GI:6319352
Saccharomyces cerevisiae (Sce) YAR075w GI:6319353
Saccharomyces cerevisiae (Sce) YHR216w
(S000001259)		 GI:6322012 P38697
Saccharomyces cerevisiae (Sce) YLR432w
(S000004424)		 GI:6323464 P50095
Saccharomyces cerevisiae (Sce) YML056c
(S000004520)		 GI:6323585 P50094
Schizosaccharomyces pombe (Spo) SPBC2F12.14c GI:19112494 O14344


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
SceS000001259
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000004424
GO:0005575 cellular_component C
ND
AthAt1g16350
GO:0005737 cytoplasm C
IDA
SceS000004520
S000004424
S000001259
GO:0005829 cytosol C
IDA
SpoSPBC2F12.14c
GO:0003682 chromatin binding F
IDA
SceS000001259
GO:0003938 IMP dehydrogenase activity F
ISS
AthAt1g79470
At1g16350
SceS000004520
SpoSPBC2F12.14c
TAS
SceS000004424
S000001259
GO:0002119 nematode larval development P
IMP
CelWBGene00017984
GO:0006177 GMP biosynthetic process P
ISS
AthAt1g16350
At1g79470
SpoSPBC2F12.14c
GO:0006183 GTP biosynthetic process P
TAS
SceS000001259
S000004424
GO:0006417 regulation of translation P
RCA
SceS000004520
S000004424
S000001259
GO:0008150 biological_process P
ND
SceS000004520
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00017984
GO:0040007 growth P
IMP
CelWBGene00017984

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68096

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) IMPDH1 GI:34328930
Canis familiaris (Cfa) IMPDH1 GI:73975841
Mus musculus (Mmu) Impdh1
(MGI:96567)		 GI:34328209 P50096
Rattus norvegicus (Rno) Impdh1 GI:109471841
Drosophila melanogaster (Dme) ras
(FBgn0003204)		 GI:24641073
Anopheles gambiae (Aga) AgaP_AGAP011133 GI:58377269
Caenorhabditis elegans (Cel) T22D1.3
(CE30188;
WBGene00020682)		 GI:71994385
Schizosaccharomyces pombe (Spo) gua1
(SPBC2F12.14c)		 GI:19112494 O14344
Saccharomyces cerevisiae (Sce) IMD4
(S000004520)		 GI:6323585 P50094
Saccharomyces cerevisiae (Sce) IMD2
(S000001259)		 GI:6322012 P38697
Saccharomyces cerevisiae (Sce) IMD3
(S000004424)		 GI:6323464 P50095
Kluyveromyces lactis (Kla) KLLA0B05511g GI:50303677
Eremothecium gossypii (Ego) AGOS_AER117W GI:45190723
Magnaporthe grisea (Mgr) MGG_03699 GI:145615920
Neurospora crassa (Ncr) NCU03117.1 GI:32420219
Plasmodium falciparum (Pfa) PFI1020c GI:124506964


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
SceS000001259
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000004424
GO:0005737 cytoplasm C
IDA
SceS000004520
S000004424
S000001259
GO:0005829 cytosol C
EXP
HsaIMPDH1
IDA
SpoSPBC2F12.14c
GO:0003682 chromatin binding F
IDA
SceS000001259
GO:0003938 IMP dehydrogenase activity F
IDA
MmuMGI:96567
ISS
DmeFBgn0003204
SceS000004520
SpoSPBC2F12.14c
NAS
DmeFBgn0003204
TAS
SceS000004424
S000001259
GO:0006164 purine nucleotide biosynthetic
process		 P
IMP
MmuMGI:96567
GO:0006177 GMP biosynthetic process P
ISS
SpoSPBC2F12.14c
NAS
DmeFBgn0003204
GO:0006183 GTP biosynthetic process P
TAS
SceS000001259
S000004424
GO:0006417 regulation of translation P
RCA
SceS000004520
S000004424
S000001259
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0003204
GO:0007411 axon guidance P
IMP
DmeFBgn0003204
GO:0008150 biological_process P
ND
SceS000004520
GO:0008152 metabolic process P
IDA
MmuMGI:96567
GO:0009168 purine ribonucleoside monophosphate biosynthetic
process		 P
EXP
HsaIMPDH1
GO:0046651 lymphocyte proliferation P
IMP
MmuMGI:96567
GO:0048477 oogenesis P
TAS
DmeFBgn0003204

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_365

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8158 ENSANGP00000012632
Ashbya gossypii (Ago) ago2622 AER117W
Arabidopsis thaliana (Ath) ath1745 At1g16350.1
Arabidopsis thaliana (Ath) ath7308 At1g79470.1
Caenorhabditis elegans (Cel) cel16015 T22D1.3a
(CE30188;
WBGene00020682)
Caenorhabditis elegans (Cel) cel16016 T22D1.3b
(CE33940)
Candida glabrata (Cgl) cgl3982 CAGL0K10780g
Cryptococcus neoformans (Cne) cne2165 181.m08182
Dictyostelium discoideum (Ddi) ddi12264 DDB0230098
Debaryomyces hansenii (Dha) dha4478 DEHA0F02068g
Drosophila melanogaster (Dme) dme17292 CG1799-PA
(FBgn0003204)
Drosophila melanogaster (Dme) dme17291 CG1799-PB
(FBgn0003204)
Drosophila melanogaster (Dme) dme17293 CG1799-PC
(FBgn0003204)
Danio rerio (Dre) dre18314 ENSDARP00000013901
Danio rerio (Dre) dre18312 ENSDARP00000024019
Danio rerio (Dre) dre31860 ENSDARP00000024354
Danio rerio (Dre) dre8754 ENSDARP00000042965
Danio rerio (Dre) dre18313 ENSDARP00000043648
Danio rerio (Dre) dre18311 ENSDARP00000044782
Danio rerio (Dre) dre8753 ENSDARP00000047276
Escherichia coli (Eco) eco2429 16130433
Takifugu rubripes (Fru) fru30848 SINFRUP00000132537
Takifugu rubripes (Fru) fru4327 SINFRUP00000145930
Takifugu rubripes (Fru) fru2950 SINFRUP00000147351
Gallus gallus (Gga) gga5355 ENSGALP00000011184
Gallus gallus (Gga) gga5353 ENSGALP00000011185
(RCJMB04_1j11)		 Q5F4A4
Homo sapiens (Hsa) hsa29380 ENSP00000265385
(IMPDH1)		 P20839-3
Homo sapiens (Hsa) hsa22465 ENSP00000321584
(IMPDH2)		 P12268
Homo sapiens (Hsa) hsa29382 ENSP00000342438
(IMPDH1)		 P20839-2
Homo sapiens (Hsa) hsa29381 ENSP00000345096
(IMPDH1)		 A4D0Z6
Homo sapiens (Hsa) hsa29383 ENSP00000346219
(IMPDH1)		 B3KRZ3
Kluyveromyces lactis (Kla) kla779 KLLA0B05511g
Mus musculus (Mmu) mmu26506 ENSMUSP00000059383
Mus musculus (Mmu) mmu21533 ENSMUSP00000077289
(MGI:96567)		 Q7TSG7
Mus musculus (Mmu) mmu28302 ENSMUSP00000079888
(MGI:109367)		 P24547
Neurospora crassa (Ncr) ncr3021 NCU03117.2
Oryza sativa (Osa) osa136 748.m00178
Oryza sativa (Osa) osa181 748.m00249
Plasmodium falciparum (Pfa) pfa4670 PFI1020c
Rattus norvegicus (Rno) rno20938 ENSRNOP00000027173
(RGD:1311108)
Rattus norvegicus (Rno) rno29288 ENSRNOP00000040635
(RGD:735092)		 Q6P9U9
Saccharomyces cerevisiae (Sce) sce3002 YHR216W
(S000001259)
Saccharomyces cerevisiae (Sce) sce4555 YLR432W
(S000004424)
Saccharomyces cerevisiae (Sce) sce4658 YML056C
(S000004520)
Schizosaccharomyces pombe (Spo) spo2405 SPBC2F12.14c O14344
Yarrowia lipolytica (Yli) yli3605 YALI0D21530g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
SceS000001259
GO:0001950 plasma membrane enriched fraction C
IDA
SceS000004424
GO:0005575 cellular_component C
ND
AthAt1g16350
GO:0005737 cytoplasm C
IDA
SceS000004520
S000004424
S000001259
GO:0005829 cytosol C
IDA
SpoSPBC2F12.14c
GO:0003682 chromatin binding F
IDA
SceS000001259
GO:0003938 IMP dehydrogenase activity F
IDA
MmuMGI:109367
MGI:96567
ISS
AthAt1g79470
At1g16350
DmeFBgn0003204
SceS000004520
SpoSPBC2F12.14c
NAS
DmeFBgn0003204
TAS
SceS000004424
S000001259
GO:0006164 purine nucleotide biosynthetic
process		 P
IMP
MmuMGI:109367
MGI:96567
GO:0006177 GMP biosynthetic process P
ISS
AthAt1g16350
At1g79470
SpoSPBC2F12.14c
NAS
DmeFBgn0003204
GO:0006183 GTP biosynthetic process P
TAS
SceS000001259
S000004424
GO:0006417 regulation of translation P
RCA
SceS000004520
S000004424
S000001259
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0003204
GO:0007411 axon guidance P
IMP
DmeFBgn0003204
GO:0008150 biological_process P
ND
SceS000004520
GO:0008152 metabolic process P
IDA
MmuMGI:96567
MGI:109367
GO:0046651 lymphocyte proliferation P
IMP
MmuMGI:109367
MGI:96567
GO:0048477 oogenesis P
TAS
DmeFBgn0003204

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC2F12.14c
(O14344)		 YML056C
(S000004520)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000004520
GO:0005829 cytosol C
IDA
SpoSPBC2F12.14c
GO:0003938 IMP dehydrogenase activity F
ISS
SceS000004520
SpoSPBC2F12.14c
GO:0006177 GMP biosynthetic process P
ISS
SpoSPBC2F12.14c
GO:0006417 regulation of translation P
RCA
SceS000004520
GO:0008150 biological_process P
ND
SceS000004520

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GO info in one table:

s.khadayate@ucl.ac.uk