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Search term: YML059C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NTE1
SGD link S000004524
Alternative ID YML059C
Description Serine esterase, homolog of human neuropathy target esterase (NTE); Nte1p-mediated phosphatidylcholine turnover influences transcription factor Opi1p localization, affecting transcriptional regulation of phospholipid biosynthesis genes
Synonyms YML059C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2968 -CDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Predicted esterase of the alpha-beta hydrolase superfamily (Neuropathy target esterase), contains cAMP-binding domains

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE03510 GI:17535221
Caenorhabditis elegans (Cel) CE25687 GI:17556915
Caenorhabditis elegans (Cel) CE29641 GI:17556917
Drosophila melanogaster (Dme) 7290863 GI:7290863
Homo sapiens (Hsa) Hs5729951 GI:5729951
Homo sapiens (Hsa) Hs22046677 GI:22046677
Homo sapiens (Hsa) Hs20537616 GI:20537616
Saccharomyces cerevisiae (Sce) YML059c
(S000004524)
GI:6323581 Q04958
Schizosaccharomyces pombe (Spo) SPCC4B3.04c GI:19075586 Q9USJ4
Encephalitozoon cuniculi (Ecu) ECU05g0070 GI:19173544 Q8SVN8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCC4B3.04c
GO:0005783 endoplasmic reticulum C
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0005789 endoplasmic reticulum membrane C
NAS
SpoSPCC4B3.04c
GO:0004091 carboxylesterase activity F
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0004622 lysophospholipase activity F
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0034638 phosphatidylcholine catabolic process P
IMP
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0044242 cellular lipid catabolic process P
ISS
SpoSPCC4B3.04c
GO:0071071 regulation of phospholipid biosynthetic
process
P
IMP
SceS000004524

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117886

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) nte1
(SPCC4B3.04c)
GI:19075586 Q9USJ4
Saccharomyces cerevisiae (Sce) NTE1
(S000004524)
GI:6323581 Q04958
Kluyveromyces lactis (Kla) KLLA0B05225g GI:50303651
Eremothecium gossypii (Ego) AGOS_AER124W GI:45190729
Magnaporthe grisea (Mgr) MGG_06143 GI:145603292
Neurospora crassa (Ncr) NCU08276.1 GI:32417008


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCC4B3.04c
GO:0005783 endoplasmic reticulum C
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0005789 endoplasmic reticulum membrane C
NAS
SpoSPCC4B3.04c
GO:0004091 carboxylesterase activity F
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0004622 lysophospholipase activity F
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0034638 phosphatidylcholine catabolic process P
IMP
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0044242 cellular lipid catabolic process P
ISS
SpoSPCC4B3.04c
GO:0071071 regulation of phospholipid biosynthetic
process
P
IMP
SceS000004524

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_649

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga12802 ENSANGP00000017169
Anopheles gambiae (Aga) aga15084 ENSANGP00000020064
Ashbya gossypii (Ago) ago2628 AER124W
Caenorhabditis elegans (Cel) cel21859 ZK370.4a
(CE34454;
WBGene00022718)
Caenorhabditis elegans (Cel) cel21860 ZK370.4b
(CE34455)
Candida glabrata (Cgl) cgl4561 CAGL0L11154g
Cryptococcus neoformans (Cne) cne537 163.m06480
Debaryomyces hansenii (Dha) dha3466 DEHA0E05126g
Drosophila melanogaster (Dme) dme16915 CG2212-PA
(FBgn0003656)
Danio rerio (Dre) dre19092 ENSDARP00000009731
Danio rerio (Dre) dre7415 ENSDARP00000010678
(im:7148262)
Q561Q2
Danio rerio (Dre) dre919 ENSDARP00000014347
Danio rerio (Dre) dre7414 ENSDARP00000027364
Danio rerio (Dre) dre915 ENSDARP00000035367
Danio rerio (Dre) dre917 ENSDARP00000040171
Danio rerio (Dre) dre918 ENSDARP00000045499
(LOC560986)
Danio rerio (Dre) dre916 ENSDARP00000049715
(LOC560986)
Escherichia coli (Eco) eco1197 16129195
Encephalitozoon cuniculi (Ecu) ecu1106 19173544
Takifugu rubripes (Fru) fru11315 SINFRUP00000135019
Takifugu rubripes (Fru) fru17513 SINFRUP00000155782
Takifugu rubripes (Fru) fru11316 SINFRUP00000176199
Takifugu rubripes (Fru) fru11317 SINFRUP00000176434
Gallus gallus (Gga) gga25491 ENSGALP00000012784
Gallus gallus (Gga) gga25490 ENSGALP00000012785
(LOC776539)
Gallus gallus (Gga) gga8175 ENSGALP00000014200
(PNPLA7)
Homo sapiens (Hsa) hsa15481 ENSP00000221249
(PNPLA6)
Q8IY17-2
Homo sapiens (Hsa) hsa32312 ENSP00000277531
(PNPLA7)
Q6ZV29-1
Kluyveromyces lactis (Kla) kla765 KLLA0B05225g
Mus musculus (Mmu) mmu25528 ENSMUSP00000004681
(MGI:1354723)
Q3TRM4-3
Mus musculus (Mmu) mmu14180 ENSMUSP00000043208
Mus musculus (Mmu) mmu14179 ENSMUSP00000044078
(MGI:2385325)
A2AJ88-1
Neurospora crassa (Ncr) ncr8065 NCU08276.2
Rattus norvegicus (Rno) rno7943 ENSRNOP00000001298
(RGD:1564611)
Rattus norvegicus (Rno) rno18247 ENSRNOP00000011140
Rattus norvegicus (Rno) rno18248 ENSRNOP00000011633
(RGD:708466)
Q5BK26
Rattus norvegicus (Rno) rno18249 ENSRNOP00000050420
(RGD:708466)
Saccharomyces cerevisiae (Sce) sce4663 YML059C
(S000004524)
Schizosaccharomyces pombe (Spo) spo1588 SPCC4B3.04c Q9USJ4
Yarrowia lipolytica (Yli) yli1192 YALI0B11044g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
ISS
MmuMGI:1354723
GO:0005737 cytoplasm C
IDA
SpoSPCC4B3.04c
GO:0005783 endoplasmic reticulum C
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0005789 endoplasmic reticulum membrane C
NAS
SpoSPCC4B3.04c
GO:0004091 carboxylesterase activity F
IDA
SceS000004524
ISO
MmuMGI:2385325
ISS
MmuMGI:1354723
SpoSPCC4B3.04c
GO:0004622 lysophospholipase activity F
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0001525 angiogenesis P
IMP
MmuMGI:1354723
GO:0006643 membrane lipid metabolic process P
IDA
DmeFBgn0003656
GO:0007420 brain development P
NAS
DmeFBgn0003656
GO:0007608 sensory perception of smell P
IMP
DmeFBgn0003656
GO:0008152 metabolic process P
ISS
MmuMGI:1354723
GO:0009887 organ morphogenesis P
IMP
MmuMGI:1354723
GO:0016044 cellular membrane organization P
IDA
DmeFBgn0003656
GO:0034638 phosphatidylcholine catabolic process P
IMP
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0044242 cellular lipid catabolic process P
ISS
SpoSPCC4B3.04c
GO:0046470 phosphatidylcholine metabolic process P
IDA
DmeFBgn0003656
GO:0051402 neuron apoptosis P
IMP
DmeFBgn0003656
GO:0071071 regulation of phospholipid biosynthetic
process
P
IMP
SceS000004524

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC4B3.04c
(Q9USJ4)
YML059C
(S000004524)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPCC4B3.04c
GO:0005783 endoplasmic reticulum C
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0005789 endoplasmic reticulum membrane C
NAS
SpoSPCC4B3.04c
GO:0004091 carboxylesterase activity F
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0004622 lysophospholipase activity F
IDA
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0034638 phosphatidylcholine catabolic process P
IMP
SceS000004524
ISS
SpoSPCC4B3.04c
GO:0044242 cellular lipid catabolic process P
ISS
SpoSPCC4B3.04c
GO:0071071 regulation of phospholipid biosynthetic
process
P
IMP
SceS000004524

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Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk