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Search term: YML061C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PIF1
SGD link S000004526
Alternative ID YML061C
Description DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA
Synonyms YML061C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0987 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING DNA helicase PIF1/RRM3

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g35940 GI:15220267
Arabidopsis thaliana (Ath) At1g49310 GI:15222100
Arabidopsis thaliana (Ath) At1g52960 GI:15219133
Arabidopsis thaliana (Ath) At1g54430 GI:15221815
Arabidopsis thaliana (Ath) At1g64410_2 GI:15217632
Arabidopsis thaliana (Ath) At2g05080 GI:15224467
Arabidopsis thaliana (Ath) At2g05640 GI:15224578
Arabidopsis thaliana (Ath) At2g07620 GI:15226033
Arabidopsis thaliana (Ath) At2g14300 GI:15225628
Arabidopsis thaliana (Ath) At2g14470 GI:15225944
Arabidopsis thaliana (Ath) At3g13250 GI:15231181
Arabidopsis thaliana (Ath) At3g30420 GI:15230775
Arabidopsis thaliana (Ath) At3g30560 GI:15230800
Arabidopsis thaliana (Ath) At3g31980 GI:15231996
Arabidopsis thaliana (Ath) At3g42100 GI:15228453
Arabidopsis thaliana (Ath) At3g42320 GI:15228514
Arabidopsis thaliana (Ath) At3g42340 GI:15228519
Arabidopsis thaliana (Ath) At3g42420_2 GI:15228541
Arabidopsis thaliana (Ath) At3g43330 GI:15229264
Arabidopsis thaliana (Ath) At3g43350 GI:15229268
Arabidopsis thaliana (Ath) At3g51690 GI:15230561
Arabidopsis thaliana (Ath) At3g51700 GI:15230563
Arabidopsis thaliana (Ath) At4g03690 GI:15236364
Arabidopsis thaliana (Ath) At4g04300 GI:15233448
Arabidopsis thaliana (Ath) At4g07800 GI:15235833
Arabidopsis thaliana (Ath) At5g28230_2 GI:15241731
Arabidopsis thaliana (Ath) At5g28670 GI:15241878
Arabidopsis thaliana (Ath) At5g28780 GI:15241916
Arabidopsis thaliana (Ath) At5g32630 GI:15242742
Arabidopsis thaliana (Ath) At5g34960_2 GI:15242901
Arabidopsis thaliana (Ath) At5g35130 GI:15238402
Arabidopsis thaliana (Ath) At5g37110 GI:15240111
Caenorhabditis elegans (Cel) CE05256
(WBGene00007523)
GI:17550334 Q17908
Caenorhabditis elegans (Cel) CE09347
(WBGene00008695)
GI:17506591
Caenorhabditis elegans (Cel) CE10858_1 GI:17568025 Q9GZI2
Caenorhabditis elegans (Cel) CE10860
(WBGene00018712)
GI:17568027 Q9GZI1
Caenorhabditis elegans (Cel) CE15283A GI:17536913 O17306
Caenorhabditis elegans (Cel) CE15283B GI:17536913 O17306
Caenorhabditis elegans (Cel) CE15285 GI:17537853
Caenorhabditis elegans (Cel) CE17043
(WBGene00018020)
GI:17533663 O44843
Caenorhabditis elegans (Cel) CE19929
(WBGene00010402)
GI:17507935 Q9XX93
Caenorhabditis elegans (Cel) CE20911
(WBGene00019136)
GI:17534623 Q9N5Q7
Caenorhabditis elegans (Cel) CE21950
(WBGene00021577)
GI:17537113 Q9N4X4
Caenorhabditis elegans (Cel) CE24155
(WBGene00013816)
GI:17566502 Q9U3T4
Caenorhabditis elegans (Cel) CE25406A GI:17537443 Q9N671
Caenorhabditis elegans (Cel) CE25406B GI:17537443 Q9N671
Caenorhabditis elegans (Cel) CE26057_1 GI:17536989
Caenorhabditis elegans (Cel) CE26961 GI:17509757
Caenorhabditis elegans (Cel) CE26962 GI:17509759
Drosophila melanogaster (Dme) 7295800
(FBgn0031540)
GI:19920652
Homo sapiens (Hsa) Hs13376578 GI:13376578
Homo sapiens (Hsa) Hs15300290 GI:15300290
Saccharomyces cerevisiae (Sce) YHR031c
(S000001073)
GI:6321820 P38766
Saccharomyces cerevisiae (Sce) YML061c
(S000004526)
GI:6323579 P07271
Schizosaccharomyces pombe (Spo) SPBC887.14c GI:19113280 Q9UUA2
Arabidopsis thaliana (Ath) At1g35940 GI:15220267
Arabidopsis thaliana (Ath) At1g49310 GI:15222100
Arabidopsis thaliana (Ath) At1g52960 GI:15219133
Arabidopsis thaliana (Ath) At1g54430 GI:15221815
Arabidopsis thaliana (Ath) At1g64410_2 GI:15217632
Arabidopsis thaliana (Ath) At2g05080 GI:15224467
Arabidopsis thaliana (Ath) At2g05640 GI:15224578
Arabidopsis thaliana (Ath) At2g07620 GI:15226033
Arabidopsis thaliana (Ath) At2g14300 GI:15225628
Arabidopsis thaliana (Ath) At2g14470 GI:15225944
Arabidopsis thaliana (Ath) At3g13250 GI:15231181
Arabidopsis thaliana (Ath) At3g30420 GI:15230775
Arabidopsis thaliana (Ath) At3g30560 GI:15230800
Arabidopsis thaliana (Ath) At3g31980 GI:15231996
Arabidopsis thaliana (Ath) At3g42100 GI:15228453
Arabidopsis thaliana (Ath) At3g42320 GI:15228514
Arabidopsis thaliana (Ath) At3g42340 GI:15228519
Arabidopsis thaliana (Ath) At3g42420_2 GI:15228541
Arabidopsis thaliana (Ath) At3g43330 GI:15229264
Arabidopsis thaliana (Ath) At3g43350 GI:15229268
Arabidopsis thaliana (Ath) At3g51690 GI:15230561
Arabidopsis thaliana (Ath) At3g51700 GI:15230563
Arabidopsis thaliana (Ath) At4g03690 GI:15236364
Arabidopsis thaliana (Ath) At4g04300 GI:15233448
Arabidopsis thaliana (Ath) At4g07800 GI:15235833
Arabidopsis thaliana (Ath) At5g28230_2 GI:15241731
Arabidopsis thaliana (Ath) At5g28670 GI:15241878
Arabidopsis thaliana (Ath) At5g28780 GI:15241916
Arabidopsis thaliana (Ath) At5g32630 GI:15242742
Arabidopsis thaliana (Ath) At5g34960_2 GI:15242901
Arabidopsis thaliana (Ath) At5g35130 GI:15238402
Arabidopsis thaliana (Ath) At5g37110 GI:15240111
Caenorhabditis elegans (Cel) CE05256
(WBGene00007523)
GI:17550334 Q17908
Caenorhabditis elegans (Cel) CE09347
(WBGene00008695)
GI:17506591
Caenorhabditis elegans (Cel) CE10858_1 GI:17568025 Q9GZI2
Caenorhabditis elegans (Cel) CE10860
(WBGene00018712)
GI:17568027 Q9GZI1
Caenorhabditis elegans (Cel) CE15283A GI:17536913 O17306
Caenorhabditis elegans (Cel) CE15283B GI:17536913 O17306
Caenorhabditis elegans (Cel) CE15285 GI:17537853
Caenorhabditis elegans (Cel) CE17043
(WBGene00018020)
GI:17533663 O44843
Caenorhabditis elegans (Cel) CE19929
(WBGene00010402)
GI:17507935 Q9XX93
Caenorhabditis elegans (Cel) CE20911
(WBGene00019136)
GI:17534623 Q9N5Q7
Caenorhabditis elegans (Cel) CE21950
(WBGene00021577)
GI:17537113 Q9N4X4
Caenorhabditis elegans (Cel) CE24155
(WBGene00013816)
GI:17566502 Q9U3T4
Caenorhabditis elegans (Cel) CE25406A GI:17537443 Q9N671
Caenorhabditis elegans (Cel) CE25406B GI:17537443 Q9N671
Caenorhabditis elegans (Cel) CE26057_1 GI:17536989
Caenorhabditis elegans (Cel) CE26961 GI:17509757
Caenorhabditis elegans (Cel) CE26962 GI:17509759
Drosophila melanogaster (Dme) 7295800
(FBgn0031540)
GI:19920652
Homo sapiens (Hsa) Hs13376578 GI:13376578
Homo sapiens (Hsa) Hs15300290 GI:15300290
Saccharomyces cerevisiae (Sce) YHR031c
(S000001073)
GI:6321820 P38766
Saccharomyces cerevisiae (Sce) YML061c
(S000004526)
GI:6323579 P07271
Schizosaccharomyces pombe (Spo) SPBC887.14c GI:19113280 Q9UUA2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g51690
At3g51700
At5g28780
GO:0005634 nucleus C
IC
SceS000004526
IDA
SpoSPBC887.14c
GO:0005657 replication fork C
IDA
SceS000001073
IMP
SceS000001073
GO:0005724 nuclear telomeric heterochromatin C
IPI
SceS000001073
GO:0005730 nucleolus C
IDA
SpoSPBC887.14c
GO:0005739 mitochondrion C
IDA
SceS000004526
SpoSPBC887.14c
GO:0003674 molecular_function F
ND
AthAt5g28780
At3g51690
At1g49310
At3g51700
GO:0003678 DNA helicase activity F
IDA
SceS000004526
IMP
SceS000001073
ISS
SceS000001073
GO:0004003 ATP-dependent DNA helicase activity F
IDA
SceS000001073
GO:0005524 ATP binding F
ISS
SpoSPBC887.14c
GO:0010521 telomerase inhibitor activity F
IDA
SceS000004526
IMP
SceS000004526
GO:0043141 ATP-dependent 5'-3' DNA helicase
activity
F
IDA
SpoSPBC887.14c
GO:0000002 mitochondrial genome maintenance P
IGI
SceS000001073
IMP
SceS000004526
GO:0000723 telomere maintenance P
IMP
SceS000004526
SpoSPBC887.14c
GO:0006200 ATP catabolic process P
IDA
SpoSPBC887.14c
GO:0006260 DNA replication P
IGI
SceS000001073
IMP
SceS000001073
IPI
SceS000001073
GO:0006281 DNA repair P
IMP
SpoSPBC887.14c
GO:0006310 DNA recombination P
IMP
SceS000004526
ISS
SpoSPBC887.14c
GO:0008150 biological_process P
ND
AthAt1g49310
At3g51690
At5g28780
At3g51700
GO:0010389 regulation of G2/M transition of mitotic cell
cycle
P
IMP
SpoSPBC887.14c
GO:0032211 negative regulation of telomere maintenance via
telomerase
P
IDA
SceS000004526
IMP
SceS000004526
GO:0033567 DNA replication, Okazaki fragment
processing
P
IGI
SpoSPBC887.14c
GO:0043137 DNA replication, removal of RNA
primer
P
IGI
SpoSPBC887.14c
GO:0043504 mitochondrial DNA repair P
IMP
SpoSPBC887.14c
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000001073
GO:0051098 regulation of binding P
RCA
SceS000004526
GO:0051276 chromosome organization P
IMP
SceS000004526

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117885

Species Gene ID NCBI link UniProt link
Rattus norvegicus (Rno) LOC690796 GI:109513868
Rattus norvegicus (Rno) Pif1 GI:109483657
Gallus gallus (Gga) PIF1 GI:118094496
Saccharomyces cerevisiae (Sce) PIF1
(S000004526)
GI:6323579 P07271
Kluyveromyces lactis (Kla) KLLA0B05137g GI:50303643
Eremothecium gossypii (Ego) AGOS_AER128W GI:45190733


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000004526
GO:0005739 mitochondrion C
IDA
SceS000004526
GO:0003678 DNA helicase activity F
IDA
SceS000004526
GO:0010521 telomerase inhibitor activity F
IDA
SceS000004526
IMP
SceS000004526
GO:0000002 mitochondrial genome maintenance P
IMP
SceS000004526
GO:0000723 telomere maintenance P
IMP
SceS000004526
GO:0006310 DNA recombination P
IMP
SceS000004526
GO:0032211 negative regulation of telomere maintenance via
telomerase
P
IDA
SceS000004526
IMP
SceS000004526
GO:0051098 regulation of binding P
RCA
SceS000004526
GO:0051276 chromosome organization P
IMP
SceS000004526

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2490

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga9681 ENSANGP00000010202
Ashbya gossypii (Ago) ago2632 AER128W
Ashbya gossypii (Ago) ago2735 AER233C
Arabidopsis thaliana (Ath) ath15606 At3g43350.1
Caenorhabditis elegans (Cel) cel17929 Y18H1A.6
(CE30311;
WBGene00004028)
Candida glabrata (Cgl) cgl3015 CAGL0J00517g
Candida glabrata (Cgl) cgl4563 CAGL0L11198g
Cryptococcus neoformans (Cne) cne5405 179.m00258
Dictyostelium discoideum (Ddi) ddi566 DDB0202221
Dictyostelium discoideum (Ddi) ddi5604 DDB0204299
Debaryomyces hansenii (Dha) dha3468 DEHA0E05170g
Debaryomyces hansenii (Dha) dha4100 DEHA0E19404g
Drosophila melanogaster (Dme) dme593 CG3238-PA
(FBgn0031540)
Danio rerio (Dre) dre10946 ENSDARP00000022087
(zgc:56161)
Q7ZV90
Takifugu rubripes (Fru) fru22035 SINFRUP00000172011
Gallus gallus (Gga) gga22615 ENSGALP00000014682
(PIF1)
Homo sapiens (Hsa) hsa10770 ENSP00000268043
(PIF1)
Q9H611-1
Kluyveromyces lactis (Kla) kla761 KLLA0B05137g
Kluyveromyces lactis (Kla) kla2657 KLLA0D13354g
Mus musculus (Mmu) mmu27829 ENSMUSP00000048432
Mus musculus (Mmu) mmu27830 ENSMUSP00000049046
(MGI:2143057)
Q80SX8-1
Neurospora crassa (Ncr) ncr414 NCU00428.2
Rattus norvegicus (Rno) rno28820 ENSRNOP00000021265
(RGD:1586053)
Q1HG60
Rattus norvegicus (Rno) rno28819 ENSRNOP00000041741
Saccharomyces cerevisiae (Sce) sce2780 YHR031C
(S000001073)
Saccharomyces cerevisiae (Sce) sce4665 YML061C
(S000004526)
Schizosaccharomyces pombe (Spo) spo1498 SPBC887.14c Q9UUA2
Yarrowia lipolytica (Yli) yli1272 YALI0B12892g
Yarrowia lipolytica (Yli) yli2816 YALI0D02607g