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Search term: YML065W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ORC1
SGD link S000004530
Alternative ID YML065W
Description Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity
Synonyms YML065W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1514 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Origin recognition complex, subunit 1, and related proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g12620 GI:15235420
Arabidopsis thaliana (Ath) At4g14700 GI:7488165
Caenorhabditis elegans (Cel) CE19131
(WBGene00012650)		 GI:17555708 Q9XX17
Drosophila melanogaster (Dme) 7304200
(FBgn0022772)		 GI:17137456
Homo sapiens (Hsa) Hs22057349 GI:22057349
Homo sapiens (Hsa) Hs4758850 GI:4758850
Saccharomyces cerevisiae (Sce) YLR442c
(S000004434)		 GI:6323475 P06701
Saccharomyces cerevisiae (Sce) YML065w
(S000004530)		 GI:6323575 P54784
Schizosaccharomyces pombe (Spo) SPBC29A10.15 GI:19112852 P54789
Encephalitozoon cuniculi (Ecu) ECU03g1030 GI:19173061 Q8SS92


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
SceS000004434
GO:0000783 nuclear telomere cap complex C
IDA
SceS000004434
GO:0000790 nuclear chromatin C
IDA
SpoSPBC29A10.15
GO:0000808 origin recognition complex C
ISS
AthAt4g14700
At4g12620
GO:0005634 nucleus C
IDA
SceS000004530
SpoSPBC29A10.15
ISS
AthAt4g14700
At4g12620
NAS
DmeFBgn0022772
GO:0005635 nuclear envelope C
RCA
SceS000004434
GO:0005656 pre-replicative complex C
IC
SpoSPBC29A10.15
IDA
SceS000004530
GO:0005664 nuclear origin of replication recognition
complex		 C
IDA
DmeFBgn0022772
SceS000004530
SpoSPBC29A10.15
IMP
SceS000004530
ISS
DmeFBgn0022772
NAS
DmeFBgn0022772
GO:0005677 chromatin silencing complex C
IDA
SceS000004434
GO:0005724 nuclear telomeric heterochromatin C
IDA
SceS000004434
GO:0005730 nucleolus C
IDA
SceS000004434
GO:0005739 mitochondrion C
IDA
SceS000004434
GO:0031261 DNA replication preinitiation complex C
IC
SpoSPBC29A10.15
IDA
SceS000004530
GO:0043596 nuclear replication fork C
IC
SpoSPBC29A10.15
GO:0003677 DNA binding F
ISS
AthAt4g14700
At4g12620
NAS
DmeFBgn0022772
GO:0003682 chromatin binding F
IDA
SceS000004530
S000004434
GO:0003688 DNA replication origin binding F
IDA
SceS000004530
SpoSPBC29A10.15
GO:0003690 double-stranded DNA binding F
IDA
SceS000004434
GO:0003697 single-stranded DNA binding F
IDA
SceS000004434
GO:0005515 protein binding F
IPI
AthAt4g12620
GO:0005524 ATP binding F
IDA
SceS000004530
IMP
SceS000004530
ISS
SpoSPBC29A10.15
GO:0010385 double-stranded methylated DNA
binding		 F
IDA
AthAt4g14700
At4g12620
GO:0016887 ATPase activity F
IMP
SceS000004530
ISS
SpoSPBC29A10.15
GO:0030527 structural constituent of chromatin F
TAS
SceS000004434
GO:0031491 nucleosome binding F
IDA
SceS000004434
GO:0031493 nucleosomal histone binding F
IDA
SceS000004434
GO:0042803 protein homodimerization activity F
IPI
SceS000004434
GO:0000003 reproduction P
IMP
CelWBGene00012650
GO:0000076 DNA replication checkpoint P
IMP
SpoSPBC29A10.15
GO:0001308 loss of chromatin silencing involved in
replicative cell aging		 P
IDA
SceS000004434
GO:0002119 nematode larval development P
IMP
CelWBGene00012650
GO:0006200 ATP catabolic process P
ISS
SpoSPBC29A10.15
GO:0006260 DNA replication P
IMP
SpoSPBC29A10.15
ISS
AthAt4g14700
At4g12620
GO:0006261 DNA-dependent DNA replication P
ISS
DmeFBgn0022772
NAS
DmeFBgn0022772
GO:0006267 pre-replicative complex assembly P
IDA
SceS000004530
IMP
SceS000004530
GO:0006270 DNA-dependent DNA replication initiation P
IDA
DmeFBgn0022772
IMP
SceS000004530
SpoSPBC29A10.15
GO:0006277 DNA amplification P
IMP
DmeFBgn0022772
GO:0006303 double-strand break repair via nonhomologous end
joining		 P
IDA
SceS000004434
GO:0006323 DNA packaging P
RCA
SceS000004434
GO:0006342 chromatin silencing P
NAS
DmeFBgn0022772
GO:0007090 regulation of S phase of mitotic cell
cycle		 P
IMP
SpoSPBC29A10.15
GO:0007568 aging P
RCA
SceS000004434
GO:0008283 cell proliferation P
IMP
DmeFBgn0022772
GO:0009567 double fertilization forming a zygote and
endosperm		 P
IMP
AthAt4g12620
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00012650
GO:0016458 gene silencing P
RCA
SceS000004530
S000004434
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IDA
SceS000004530
IGI
SceS000004434
S000004530
IMP
SceS000004434
GO:0031507 heterochromatin formation P
IMP
SceS000004434
GO:0040007 growth P
IMP
CelWBGene00012650
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000004434
S000004530
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00012650
GO:0045449 regulation of transcription P
IMP
AthAt4g12620
At4g14700
GO:0070481 nuclear-transcribed mRNA catabolic process,
non-stop decay		 P
IMP
SceS000004434

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117884

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) ORC1
(S000004530)		 GI:6323575 P54784
Kluyveromyces lactis (Kla) ORC1_KLULA GI:50303631
Eremothecium gossypii (Ego) AGOS_AER133C GI:45190738


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004530
GO:0005656 pre-replicative complex C
IDA
SceS000004530
GO:0005664 nuclear origin of replication recognition
complex		 C
IDA
SceS000004530
IMP
SceS000004530
GO:0031261 DNA replication preinitiation complex C
IDA
SceS000004530
GO:0003682 chromatin binding F
IDA
SceS000004530
GO:0003688 DNA replication origin binding F
IDA
SceS000004530
GO:0005524 ATP binding F
IDA
SceS000004530
IMP
SceS000004530
GO:0016887 ATPase activity F
IMP
SceS000004530
GO:0006267 pre-replicative complex assembly P
IDA
SceS000004530
IMP
SceS000004530
GO:0006270 DNA-dependent DNA replication initiation P
IMP
SceS000004530
GO:0016458 gene silencing P
RCA
SceS000004530
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IDA
SceS000004530
IGI
SceS000004530
GO:0040029 regulation of gene expression,
epigenetic		 P
RCA
SceS000004530

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1536

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga316 ENSANGP00000011420
Ashbya gossypii (Ago) ago2637 AER133C
Arabidopsis thaliana (Ath) ath19011 At4g12620.1
Arabidopsis thaliana (Ath) ath19260 At4g14700.1
Caenorhabditis elegans (Cel) cel18427 Y39A1A.12
(CE19131;
WBGene00012650)
Candida glabrata (Cgl) cgl4566 CAGL0L11264g
Cryptococcus neoformans (Cne) cne3153 167.m03490
Dictyostelium discoideum (Ddi) ddi6155 DDB0218435
Debaryomyces hansenii (Dha) dha2759 DEHA0D10439g
Drosophila melanogaster (Dme) dme3672 CG10667-PA
(FBgn0022772)
Danio rerio (Dre) dre19619 ENSDARP00000018115
Encephalitozoon cuniculi (Ecu) ecu468 19173061
Takifugu rubripes (Fru) fru32191 SINFRUP00000142134
Gallus gallus (Gga) gga22802 ENSGALP00000017266
(ORC1L)		 Q5ZMC5
Homo sapiens (Hsa) hsa1166 ENSP00000345877
Kluyveromyces lactis (Kla) kla755 KLLA0B05016g
Mus musculus (Mmu) mmu18590 ENSMUSP00000030325
Mus musculus (Mmu) mmu18591 ENSMUSP00000075232
(MGI:1328337)		 Q59IX2
Neurospora crassa (Ncr) ncr2870 NCU02965.2
Oryza sativa (Osa) osa23085 3722.m00153
Oryza sativa (Osa) osa62744 6511.m00164
Plasmodium falciparum (Pfa) pfa5342 PFL0150w
Rattus norvegicus (Rno) rno23616 ENSRNOP00000012492
(RGD:631435)		 Q80Z32
Rattus norvegicus (Rno) rno23617 ENSRNOP00000041406
Rattus norvegicus (Rno) rno23615 ENSRNOP00000050861
(RGD:631435)
Saccharomyces cerevisiae (Sce) sce4669 YML065W
(S000004530)
Schizosaccharomyces pombe (Spo) spo3910 SPBC29A10.15 P54789
Yarrowia lipolytica (Yli) yli522 YALI0A16038g
Yarrowia lipolytica (Yli) yli3129 YALI0D10104g